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The map label for this gene is yngJ [H]

Identifier: 94314448

GI number: 94314448

Start: 2275726

End: 2276865

Strand: Reverse

Name: yngJ [H]

Synonym: Rmet_5529

Alternate gene names: 94314448

Gene position: 2276865-2275726 (Counterclockwise)

Preceding gene: 94314449

Following gene: 94314447

Centisome position: 88.25

GC content: 59.56

Gene sequence:

>1140_bases
GTGAATTTCGAACTGAACGAGGACCAGCGGGCTCTCCAGGAAAGCGTTCATCGGCTGCTAAACGAACGCTATGGATTTGA
GAATCGCCGGCAATACGTCGAAGCTGACGCCGGCCACGACGAGAAAACTTGGAGCGCGCTGTCAGAACTTGGACTGACGG
CGCTGTTGGTTCCCGAGGACCTCGAGGGATTCGGTGGGGGCGCTGTCGACCTGTTTCCGGTTATGCAGGAGCTCGGGGCA
GTCTTGTCCCTGGAGCCGCTCCTTGCAACCAATTTCCTCCCGGCCACGGCGCTTCGCACCTACGCGGGGGACGCTCGTGC
CAAGGAAGCACTGCAGTCCATTGCATCCGGAGAGCGTCGGATTGCGTGGGCTCACGATGAAGTCGAGGCGCGTCATACGG
ATTGGTGGATCAGCACTAGAGCAACCAAGACCGGCGAAAAGTGGCTGCTTAGCGGTCAAAAGTTCAACGTTGTTGGGGCC
AATGATGCCCATCAATACTTGGTCAGCGCGCGTGTCCAAGGCTCCACTGAGGACACCGACGGTTGCGCGCTGTTCCTGGT
GAATGCCGATGCAAAGGGGCTGAGTGTTCGCAACTACAAGCTCGTGGACGATACGCCTGCCGGTGAGCTGACCTTTAGCA
ACGTGTCGGCCTTGCCGCTAGGCGAGGCTGGGGACGGACATCAATCGCTAAGAGCCATCGAGAGCGCGTTGGCCATGGGC
ATTGCCGCCGCCTGTGCAGATATGGTCGGCGCAGCAGGTGCAGCGTTCCAACTCGCCATCGAGTACGTGAATACGCGAAA
GCAGTTCGGAAGGCTGATCGGCGAGAACCAAGCGCTCCGCCATCGCGCTTCGGAAATGCTTGTGAGCCTGGAGCTCGCGA
AAAGCATGGCCATTGCGGCGGCGGTTGCGGTGGACGATCAAGACTCGGAAGGTGCAGAGCTCGATTTGCACCGAGCGAAA
TTGTCAGTAGCAAAGCATGCCCGGGCGGTGGCTCATGGTGCGATTCAGCTGCACGGAGGCATTGGCATGACTGAGGAGTA
CGCGGTAGGACACTACCTACGCCGAGTCCACGTCCTTGACCAACTTTTCGGCGATGGAGAGGCGCATACGGCAAGACTGG
CCTCGCTGCTTCACGCATAG

Upstream 100 bases:

>100_bases
GCCACGCTATTTCTATTCGCGTGCTGCAAGCATCTATGGTGGGACGAGTGAAGTGCAAAAGGACATCCTGGCCAAGGCAA
TTGTAGGATAGGGAGACAAA

Downstream 100 bases:

>100_bases
CAGCCCAACAAATACTACATGGAGGGAGACAGATTATGAGCGAAGCCACAATCTATCTGGATGGCCGCGCGAAAGCGCGA
GATGAGGTCCTGCAGCAAGC

Product: putative acyl-CoA dehydrogenase

Products: 6-carboxyhex-2-enoyl-CoA; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MNFELNEDQRALQESVHRLLNERYGFENRRQYVEADAGHDEKTWSALSELGLTALLVPEDLEGFGGGAVDLFPVMQELGA
VLSLEPLLATNFLPATALRTYAGDARAKEALQSIASGERRIAWAHDEVEARHTDWWISTRATKTGEKWLLSGQKFNVVGA
NDAHQYLVSARVQGSTEDTDGCALFLVNADAKGLSVRNYKLVDDTPAGELTFSNVSALPLGEAGDGHQSLRAIESALAMG
IAAACADMVGAAGAAFQLAIEYVNTRKQFGRLIGENQALRHRASEMLVSLELAKSMAIAAAVAVDDQDSEGAELDLHRAK
LSVAKHARAVAHGAIQLHGGIGMTEEYAVGHYLRRVHVLDQLFGDGEAHTARLASLLHA

Sequences:

>Translated_379_residues
MNFELNEDQRALQESVHRLLNERYGFENRRQYVEADAGHDEKTWSALSELGLTALLVPEDLEGFGGGAVDLFPVMQELGA
VLSLEPLLATNFLPATALRTYAGDARAKEALQSIASGERRIAWAHDEVEARHTDWWISTRATKTGEKWLLSGQKFNVVGA
NDAHQYLVSARVQGSTEDTDGCALFLVNADAKGLSVRNYKLVDDTPAGELTFSNVSALPLGEAGDGHQSLRAIESALAMG
IAAACADMVGAAGAAFQLAIEYVNTRKQFGRLIGENQALRHRASEMLVSLELAKSMAIAAAVAVDDQDSEGAELDLHRAK
LSVAKHARAVAHGAIQLHGGIGMTEEYAVGHYLRRVHVLDQLFGDGEAHTARLASLLHA
>Mature_379_residues
MNFELNEDQRALQESVHRLLNERYGFENRRQYVEADAGHDEKTWSALSELGLTALLVPEDLEGFGGGAVDLFPVMQELGA
VLSLEPLLATNFLPATALRTYAGDARAKEALQSIASGERRIAWAHDEVEARHTDWWISTRATKTGEKWLLSGQKFNVVGA
NDAHQYLVSARVQGSTEDTDGCALFLVNADAKGLSVRNYKLVDDTPAGELTFSNVSALPLGEAGDGHQSLRAIESALAMG
IAAACADMVGAAGAAFQLAIEYVNTRKQFGRLIGENQALRHRASEMLVSLELAKSMAIAAAVAVDDQDSEGAELDLHRAK
LSVAKHARAVAHGAIQLHGGIGMTEEYAVGHYLRRVHVLDQLFGDGEAHTARLASLLHA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7656849, Length=319, Percent_Identity=25.705329153605, Blast_Score=86, Evalue=8e-17,
Organism=Homo sapiens, GI4501859, Length=362, Percent_Identity=25.1381215469613, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI4557231, Length=393, Percent_Identity=24.9363867684478, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI187960098, Length=393, Percent_Identity=24.9363867684478, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI226958412, Length=384, Percent_Identity=24.7395833333333, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI4557233, Length=332, Percent_Identity=25.3012048192771, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI226958414, Length=344, Percent_Identity=24.7093023255814, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI21361497, Length=377, Percent_Identity=24.9336870026525, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI87081958, Length=363, Percent_Identity=25.6198347107438, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1786223, Length=370, Percent_Identity=24.8648648648649, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17533517, Length=323, Percent_Identity=25.3869969040248, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17538396, Length=383, Percent_Identity=25.5874673629243, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17570075, Length=407, Percent_Identity=25.3071253071253, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17506239, Length=338, Percent_Identity=26.0355029585799, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17508101, Length=317, Percent_Identity=26.813880126183, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71985184, Length=329, Percent_Identity=25.531914893617, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17569725, Length=395, Percent_Identity=23.2911392405063, Blast_Score=71, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17534899, Length=392, Percent_Identity=23.7244897959184, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71990804, Length=264, Percent_Identity=26.8939393939394, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21355753, Length=363, Percent_Identity=26.7217630853994, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21356377, Length=377, Percent_Identity=25.7294429708223, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24666513, Length=366, Percent_Identity=24.8633879781421, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24660351, Length=400, Percent_Identity=25.75, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24646207, Length=382, Percent_Identity=25.6544502617801, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.1.62

Molecular weight: Translated: 40859; Mature: 40859

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFELNEDQRALQESVHRLLNERYGFENRRQYVEADAGHDEKTWSALSELGLTALLVPED
CCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHHHHHCCCEEEEECCC
LEGFGGGAVDLFPVMQELGAVLSLEPLLATNFLPATALRTYAGDARAKEALQSIASGERR
CCCCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHCCCCE
IAWAHDEVEARHTDWWISTRATKTGEKWLLSGQKFNVVGANDAHQYLVSARVQGSTEDTD
EEEECCHHCCCCCCEEEEECCCCCCCHHEECCCEEEEECCCHHHHHHHHHHCCCCCCCCC
GCALFLVNADAKGLSVRNYKLVDDTPAGELTFSNVSALPLGEAGDGHQSLRAIESALAMG
CEEEEEEECCCCCCEEEEEEEECCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHH
IAAACADMVGAAGAAFQLAIEYVNTRKQFGRLIGENQALRHRASEMLVSLELAKSMAIAA
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
AVAVDDQDSEGAELDLHRAKLSVAKHARAVAHGAIQLHGGIGMTEEYAVGHYLRRVHVLD
HEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHH
QLFGDGEAHTARLASLLHA
HHHCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MNFELNEDQRALQESVHRLLNERYGFENRRQYVEADAGHDEKTWSALSELGLTALLVPED
CCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHHHHHCCCEEEEECCC
LEGFGGGAVDLFPVMQELGAVLSLEPLLATNFLPATALRTYAGDARAKEALQSIASGERR
CCCCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHCCCCE
IAWAHDEVEARHTDWWISTRATKTGEKWLLSGQKFNVVGANDAHQYLVSARVQGSTEDTD
EEEECCHHCCCCCCEEEEECCCCCCCHHEECCCEEEEECCCHHHHHHHHHHCCCCCCCCC
GCALFLVNADAKGLSVRNYKLVDDTPAGELTFSNVSALPLGEAGDGHQSLRAIESALAMG
CEEEEEEECCCCCCEEEEEEEECCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHH
IAAACADMVGAAGAAFQLAIEYVNTRKQFGRLIGENQALRHRASEMLVSLELAKSMAIAA
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
AVAVDDQDSEGAELDLHRAKLSVAKHARAVAHGAIQLHGGIGMTEEYAVGHYLRRVHVLD
HEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHH
QLFGDGEAHTARLASLLHA
HHHCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: pimeloyl-CoA; NAD+

Specific reaction: pimeloyl-CoA + NAD+ = 6-carboxyhex-2-enoyl-CoA + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]