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The map label for this gene is bcd [H]

Identifier: 94314449

GI number: 94314449

Start: 2276875

End: 2278035

Strand: Reverse

Name: bcd [H]

Synonym: Rmet_5530

Alternate gene names: 94314449

Gene position: 2278035-2276875 (Counterclockwise)

Preceding gene: 291481582

Following gene: 94314448

Centisome position: 88.29

GC content: 57.71

Gene sequence:

>1161_bases
ATGGATCTACGATTGTCGCCTGCACAAGAAGCCTTTCGTGCAGAAGTTCGTGCCTTTATTGAAGAGAGGCTGCCTGAGGA
CATCCGTGCTCGGCTGCGCGCAGGGCACCCGGCCCAAAAGGAAGACACGGTGACGTGGCAGCGGATTCTCAATGAGCGCG
GCTGGGCAGCGCCCCATTGGCCGCGGAAGTTTGGAGGAGCCGAGCTCGGGCAGTTGGAAAGGCTCATTCTGCTTGACGAG
ATGTTCCGCGCACCGACACCGCTTCCTCAGGTGTTCAACGTCACGATGCTGGGGCCGGTGCTGATGAAGTTCGGTACGCC
GGAGCAGTGCGAGTACTTCCTGCCCAAGCTAGCCAATCTCGACCTCTGGTTTTGCCAAGGCTTTTCCGAGCCAGGTTCGG
GCTCGGATCTGGCTTCCTTGCGGACCGCCGCCAAACGAGACGGCGACCACTATGTTGTCAATGGACAGAAGATCTGGACC
ACCACAGCTCATTGGGCGGATTGGGTGTTTGCACTTGTTCGGACCAATCCCGAGGCGAAGAAGCAGGAGGGGATTTCGTT
CCTGCTGATTGACCTGAAGTCGCCTGGCATCACGATCCGTCCTATCCGCTCCATTGATGGCGACCATCATTTGAATGAGG
TCTTCTTTGATGATGTCCGGGTGCCCGTCGAGAACCTTGTGGGCGAGGAGAACAAGGGCTGGAACTGCGCAAAGTTCCTT
CTTGGAAACGAGAGAACCGGCATTGCCAATGTGGGCCTGTGCCGAGAGCGTTTGGATTACGCGCGCGAGCTCGCAGATCG
CACTGTTCAGGGTGAAAACAGGCTCATCGACGACCCCAAGCTGCGATCGGAGATCGCGACGCTGGACGCCGAAGTACGAG
CTCTAGAGGTAACGAACTGGCGTTTTCTTCTTACCCCCAATGAGCAGGCGCGCATCCCCGCGTTCGCATCGGTGCTGAAA
CTCAAAGGTGTCGAGCTGCAACAAGACATCAATGCCCTGCTGGCTCGCCTTGCCGGACCACAGGGCTTGGAAAAGCGCGG
CAAGAGGGATACGGACCGTGGTCCGCTAACGCCACGCTATTTCTATTCGCGTGCTGCAAGCATCTATGGTGGGACGAGTG
AAGTGCAAAAGGACATCCTGGCCAAGGCAATTGTAGGATAG

Upstream 100 bases:

>100_bases
GCCTCCCACATCTCACAATCCTCTTGCGTTAAGTATAATGGTTGAACCAAAATAACGCACGTACTCGCACGGCGCGAGTC
GACGTAGGAGGAGAAGAAGG

Downstream 100 bases:

>100_bases
GGAGACAAAGTGAATTTCGAACTGAACGAGGACCAGCGGGCTCTCCAGGAAAGCGTTCATCGGCTGCTAAACGAACGCTA
TGGATTTGAGAATCGCCGGC

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; SCAD [H]

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MDLRLSPAQEAFRAEVRAFIEERLPEDIRARLRAGHPAQKEDTVTWQRILNERGWAAPHWPRKFGGAELGQLERLILLDE
MFRAPTPLPQVFNVTMLGPVLMKFGTPEQCEYFLPKLANLDLWFCQGFSEPGSGSDLASLRTAAKRDGDHYVVNGQKIWT
TTAHWADWVFALVRTNPEAKKQEGISFLLIDLKSPGITIRPIRSIDGDHHLNEVFFDDVRVPVENLVGEENKGWNCAKFL
LGNERTGIANVGLCRERLDYARELADRTVQGENRLIDDPKLRSEIATLDAEVRALEVTNWRFLLTPNEQARIPAFASVLK
LKGVELQQDINALLARLAGPQGLEKRGKRDTDRGPLTPRYFYSRAASIYGGTSEVQKDILAKAIVG

Sequences:

>Translated_386_residues
MDLRLSPAQEAFRAEVRAFIEERLPEDIRARLRAGHPAQKEDTVTWQRILNERGWAAPHWPRKFGGAELGQLERLILLDE
MFRAPTPLPQVFNVTMLGPVLMKFGTPEQCEYFLPKLANLDLWFCQGFSEPGSGSDLASLRTAAKRDGDHYVVNGQKIWT
TTAHWADWVFALVRTNPEAKKQEGISFLLIDLKSPGITIRPIRSIDGDHHLNEVFFDDVRVPVENLVGEENKGWNCAKFL
LGNERTGIANVGLCRERLDYARELADRTVQGENRLIDDPKLRSEIATLDAEVRALEVTNWRFLLTPNEQARIPAFASVLK
LKGVELQQDINALLARLAGPQGLEKRGKRDTDRGPLTPRYFYSRAASIYGGTSEVQKDILAKAIVG
>Mature_386_residues
MDLRLSPAQEAFRAEVRAFIEERLPEDIRARLRAGHPAQKEDTVTWQRILNERGWAAPHWPRKFGGAELGQLERLILLDE
MFRAPTPLPQVFNVTMLGPVLMKFGTPEQCEYFLPKLANLDLWFCQGFSEPGSGSDLASLRTAAKRDGDHYVVNGQKIWT
TTAHWADWVFALVRTNPEAKKQEGISFLLIDLKSPGITIRPIRSIDGDHHLNEVFFDDVRVPVENLVGEENKGWNCAKFL
LGNERTGIANVGLCRERLDYARELADRTVQGENRLIDDPKLRSEIATLDAEVRALEVTNWRFLLTPNEQARIPAFASVLK
LKGVELQQDINALLARLAGPQGLEKRGKRDTDRGPLTPRYFYSRAASIYGGTSEVQKDILAKAIVG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=336, Percent_Identity=27.9761904761905, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI187960098, Length=399, Percent_Identity=25.5639097744361, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI4557231, Length=398, Percent_Identity=25.1256281407035, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI4501857, Length=400, Percent_Identity=26.5, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI4501859, Length=348, Percent_Identity=25.8620689655172, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI7656849, Length=203, Percent_Identity=30.0492610837438, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI226958412, Length=263, Percent_Identity=27.7566539923954, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI4557235, Length=249, Percent_Identity=32.1285140562249, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI76496475, Length=248, Percent_Identity=32.258064516129, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI226958414, Length=207, Percent_Identity=29.951690821256, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI21361497, Length=265, Percent_Identity=25.6603773584906, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI38505218, Length=204, Percent_Identity=29.9019607843137, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI87081958, Length=237, Percent_Identity=27.4261603375527, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1786223, Length=276, Percent_Identity=23.1884057971014, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17506239, Length=347, Percent_Identity=28.2420749279539, Blast_Score=115, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17508101, Length=340, Percent_Identity=27.3529411764706, Blast_Score=114, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI17570075, Length=408, Percent_Identity=24.7549019607843, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17569725, Length=351, Percent_Identity=23.6467236467236, Blast_Score=104, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI71990804, Length=249, Percent_Identity=28.1124497991968, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17534899, Length=258, Percent_Identity=29.4573643410853, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI32563615, Length=230, Percent_Identity=30, Blast_Score=98, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17505929, Length=352, Percent_Identity=27.2727272727273, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17551932, Length=234, Percent_Identity=30.3418803418803, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71985192, Length=241, Percent_Identity=28.6307053941909, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI71985184, Length=213, Percent_Identity=30.0469483568075, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17538396, Length=234, Percent_Identity=27.3504273504274, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI71982178, Length=226, Percent_Identity=28.7610619469027, Blast_Score=88, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17533517, Length=221, Percent_Identity=27.1493212669683, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17562446, Length=314, Percent_Identity=25.1592356687898, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24666513, Length=352, Percent_Identity=26.9886363636364, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24660351, Length=355, Percent_Identity=27.3239436619718, Blast_Score=108, Evalue=8e-24,
Organism=Drosophila melanogaster, GI281363737, Length=304, Percent_Identity=27.9605263157895, Blast_Score=108, Evalue=8e-24,
Organism=Drosophila melanogaster, GI21356377, Length=346, Percent_Identity=26.3005780346821, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI21355753, Length=225, Percent_Identity=31.5555555555556, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24646207, Length=346, Percent_Identity=26.5895953757225, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI19920834, Length=343, Percent_Identity=26.2390670553936, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 43533; Mature: 43533

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLRLSPAQEAFRAEVRAFIEERLPEDIRARLRAGHPAQKEDTVTWQRILNERGWAAPHW
CCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCC
PRKFGGAELGQLERLILLDEMFRAPTPLPQVFNVTMLGPVLMKFGTPEQCEYFLPKLANL
CHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
DLWFCQGFSEPGSGSDLASLRTAAKRDGDHYVVNGQKIWTTTAHWADWVFALVRTNPEAK
CEEEECCCCCCCCCCHHHHHHHHHHCCCCEEEECCCEEEEEHHHHHHHHHHHHHCCCHHH
KQEGISFLLIDLKSPGITIRPIRSIDGDHHLNEVFFDDVRVPVENLVGEENKGWNCAKFL
HHCCCEEEEEEECCCCEEEEEHHCCCCCHHHHHHHHHHHCCCHHHHCCCCCCCCCHHHHH
LGNERTGIANVGLCRERLDYARELADRTVQGENRLIDDPKLRSEIATLDAEVRALEVTNW
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHEEEEEECE
RFLLTPNEQARIPAFASVLKLKGVELQQDINALLARLAGPQGLEKRGKRDTDRGPLTPRY
EEEECCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCHHH
FYSRAASIYGGTSEVQKDILAKAIVG
HHHHHHHHCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDLRLSPAQEAFRAEVRAFIEERLPEDIRARLRAGHPAQKEDTVTWQRILNERGWAAPHW
CCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCC
PRKFGGAELGQLERLILLDEMFRAPTPLPQVFNVTMLGPVLMKFGTPEQCEYFLPKLANL
CHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
DLWFCQGFSEPGSGSDLASLRTAAKRDGDHYVVNGQKIWTTTAHWADWVFALVRTNPEAK
CEEEECCCCCCCCCCHHHHHHHHHHCCCCEEEECCCEEEEEHHHHHHHHHHHHHCCCHHH
KQEGISFLLIDLKSPGITIRPIRSIDGDHHLNEVFFDDVRVPVENLVGEENKGWNCAKFL
HHCCCEEEEEEECCCCEEEEEHHCCCCCHHHHHHHHHHHCCCHHHHCCCCCCCCCHHHHH
LGNERTGIANVGLCRERLDYARELADRTVQGENRLIDDPKLRSEIATLDAEVRALEVTNW
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHEEEEEECE
RFLLTPNEQARIPAFASVLKLKGVELQQDINALLARLAGPQGLEKRGKRDTDRGPLTPRY
EEEECCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCHHH
FYSRAASIYGGTSEVQKDILAKAIVG
HHHHHHHHCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]