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The map label for this gene is ycdF [H]

Identifier: 94314421

GI number: 94314421

Start: 2245215

End: 2246030

Strand: Direct

Name: ycdF [H]

Synonym: Rmet_5502

Alternate gene names: 94314421

Gene position: 2245215-2246030 (Clockwise)

Preceding gene: 94314420

Following gene: 94314422

Centisome position: 87.02

GC content: 57.11

Gene sequence:

>816_bases
ATGCGATCTCTCAAGAACAAGACGCTATTCGTCACCGGGGCGAGTCGCGGCATCGGCCTGGCAATCGCAAAGCGGGCGGC
TCAAGATGGTGCGAACATCGTCATCGCAGCCAAATCCGCCGAGCCTCACCCCAAGCTACCAGGAACAATCTTCACAGCGG
CTCGTGAAATCGAAGAGGCAGGCGGGACAGCTTTGCCTCTCGTCGTAGATATTCGTGACGAGCAACAAGTACAGTCGGCA
GTGGACAAGGCCGTTGAACATTTCGGAGGGATTGACGTCTGCATCAACAACGCCAGTGCAATCAGCAAGACTGGCACATT
GGCCACGGACATGAAACGGTTTGACTTGATGCATAGCATCAACACACGTGGCACGTATCTCGTCACGAGAACTTGCCTTC
CGCACCTTCTGAAGTCATCCAACCCTCATGTCCTGATGCTCTCGCCTCCTCTGAATATGGAGGCGCGCTGGTTCTCGCCC
AATGTCGCTTACACGATGGCGAAATTCGGCATGAGCATGTGCGTGCTCGGGATGGCCGGGGAGTTTCGTGGACAGGTGGC
GATCAACGCTTTGTGGCCTCGGACCTTCGTTGGAACGGCGGCCGTCCAGAACATCTTGGGCGGCGAGACGACTATGAAGC
GCACCCGTCACCCGGAGATCGTCGCCGACGCTGCCTATGCCATCCTGACGAAGGACACATCCTTCACCGGGAACTTCTGC
GTCGACGAATCCGTCCTCCGTCAGGAAGGCGTTACCGATTTCAGCCAATACAGCGACTGCCCCGAATCCGACCTGATCCC
GGACTCGTTCGTTTAA

Upstream 100 bases:

>100_bases
AAGCTGCAGCTTTCTCGACGAAGGAACCGCGCGCTGCAATCGAAGCACTCCTGTCCAAACAACCTCCTCCGTTTCGCGGA
TTTCCACGGCGTTCGTAATC

Downstream 100 bases:

>100_bases
TCCTCTCGTACCATTACACCAGGAGCAACCGACCCTGCTCCTTCCCCGCATCCCTCTGTTTTGCAATCGCGTTCGGAAGT
CAGGACGCTCCGTCATGCGG

Product: short chain dehydrogenase

Products: NA

Alternate protein names: GLCDH-II; GDH-II; General stress protein 74; GSP74 [H]

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MRSLKNKTLFVTGASRGIGLAIAKRAAQDGANIVIAAKSAEPHPKLPGTIFTAAREIEEAGGTALPLVVDIRDEQQVQSA
VDKAVEHFGGIDVCINNASAISKTGTLATDMKRFDLMHSINTRGTYLVTRTCLPHLLKSSNPHVLMLSPPLNMEARWFSP
NVAYTMAKFGMSMCVLGMAGEFRGQVAINALWPRTFVGTAAVQNILGGETTMKRTRHPEIVADAAYAILTKDTSFTGNFC
VDESVLRQEGVTDFSQYSDCPESDLIPDSFV

Sequences:

>Translated_271_residues
MRSLKNKTLFVTGASRGIGLAIAKRAAQDGANIVIAAKSAEPHPKLPGTIFTAAREIEEAGGTALPLVVDIRDEQQVQSA
VDKAVEHFGGIDVCINNASAISKTGTLATDMKRFDLMHSINTRGTYLVTRTCLPHLLKSSNPHVLMLSPPLNMEARWFSP
NVAYTMAKFGMSMCVLGMAGEFRGQVAINALWPRTFVGTAAVQNILGGETTMKRTRHPEIVADAAYAILTKDTSFTGNFC
VDESVLRQEGVTDFSQYSDCPESDLIPDSFV
>Mature_271_residues
MRSLKNKTLFVTGASRGIGLAIAKRAAQDGANIVIAAKSAEPHPKLPGTIFTAAREIEEAGGTALPLVVDIRDEQQVQSA
VDKAVEHFGGIDVCINNASAISKTGTLATDMKRFDLMHSINTRGTYLVTRTCLPHLLKSSNPHVLMLSPPLNMEARWFSP
NVAYTMAKFGMSMCVLGMAGEFRGQVAINALWPRTFVGTAAVQNILGGETTMKRTRHPEIVADAAYAILTKDTSFTGNFC
VDESVLRQEGVTDFSQYSDCPESDLIPDSFV

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254986, Length=264, Percent_Identity=58.7121212121212, Blast_Score=331, Evalue=3e-91,
Organism=Homo sapiens, GI10190704, Length=211, Percent_Identity=28.9099526066351, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI33667109, Length=134, Percent_Identity=29.8507462686567, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI5031737, Length=134, Percent_Identity=29.8507462686567, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI87082100, Length=206, Percent_Identity=28.1553398058252, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1789208, Length=193, Percent_Identity=25.9067357512953, Blast_Score=64, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI71982365, Length=269, Percent_Identity=60.9665427509294, Blast_Score=342, Evalue=1e-94,
Organism=Caenorhabditis elegans, GI17558628, Length=268, Percent_Identity=64.1791044776119, Blast_Score=332, Evalue=2e-91,
Organism=Caenorhabditis elegans, GI17544670, Length=143, Percent_Identity=30.7692307692308, Blast_Score=64, Evalue=9e-11,
Organism=Drosophila melanogaster, GI21357673, Length=272, Percent_Identity=62.1323529411765, Blast_Score=344, Evalue=3e-95,
Organism=Drosophila melanogaster, GI23397609, Length=204, Percent_Identity=31.3725490196078, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28571526, Length=222, Percent_Identity=30.6306306306306, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI21357041, Length=222, Percent_Identity=28.3783783783784, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21355319, Length=219, Percent_Identity=24.2009132420091, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24644339, Length=216, Percent_Identity=27.7777777777778, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.47 [H]

Molecular weight: Translated: 29252; Mature: 29252

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSLKNKTLFVTGASRGIGLAIAKRAAQDGANIVIAAKSAEPHPKLPGTIFTAAREIEEA
CCCCCCCEEEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHC
GGTALPLVVDIRDEQQVQSAVDKAVEHFGGIDVCINNASAISKTGTLATDMKRFDLMHSI
CCCEEEEEEECCCHHHHHHHHHHHHHHHCCEEEEECCCHHHHCCCCHHHHHHHHHHHHHC
NTRGTYLVTRTCLPHLLKSSNPHVLMLSPPLNMEARWFSPNVAYTMAKFGMSMCVLGMAG
CCCCEEEEHHHHHHHHHHCCCCCEEEECCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCC
EFRGQVAINALWPRTFVGTAAVQNILGGETTMKRTRHPEIVADAAYAILTKDTSFTGNFC
CCCCEEEEEEECCHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHEEEEEECCCCCCCCEE
VDESVLRQEGVTDFSQYSDCPESDLIPDSFV
CCHHHHHHCCCCCHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MRSLKNKTLFVTGASRGIGLAIAKRAAQDGANIVIAAKSAEPHPKLPGTIFTAAREIEEA
CCCCCCCEEEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHC
GGTALPLVVDIRDEQQVQSAVDKAVEHFGGIDVCINNASAISKTGTLATDMKRFDLMHSI
CCCEEEEEEECCCHHHHHHHHHHHHHHHCCEEEEECCCHHHHCCCCHHHHHHHHHHHHHC
NTRGTYLVTRTCLPHLLKSSNPHVLMLSPPLNMEARWFSPNVAYTMAKFGMSMCVLGMAG
CCCCEEEEHHHHHHHHHHCCCCCEEEECCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCC
EFRGQVAINALWPRTFVGTAAVQNILGGETTMKRTRHPEIVADAAYAILTKDTSFTGNFC
CCCCEEEEEEECCHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHEEEEEECCCCCCCCEE
VDESVLRQEGVTDFSQYSDCPESDLIPDSFV
CCHHHHHHCCCCCHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9298659 [H]