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The map label for this gene is 94314418

Identifier: 94314418

GI number: 94314418

Start: 2242829

End: 2244004

Strand: Direct

Name: 94314418

Synonym: Rmet_5499

Alternate gene names: NA

Gene position: 2242829-2244004 (Clockwise)

Preceding gene: 94314416

Following gene: 94314419

Centisome position: 86.93

GC content: 60.54

Gene sequence:

>1176_bases
ATGACGATCAAAGGTAAGGCATGCATCGTGGGTGCTTACGAGCACCCAACACGCAAGGCACCGGATAAGACGGTTGCGCA
GTTGCACGCAGAGTGCGCGAAGGGGGCACTGGAGGACGCAGGACTGACGCTGCAGGATGTTGACGGCTACTTTTGCGCAG
GAGACGCTCCTGGCCTTGGCGCGAACAGCATGGCCGATTACCTCGGCCTCACGAACTTGCGGCATGTCGACACGACGGAC
ACCGGAGGCTCCGCATATCTAATCCACGTCTCTCACGCAGCGCAAGCGATTGCGGCGGGCAAGTGCAACGTTGCGCTCAT
TACGCTCGCGGGGCGGCCCCGCACGGAAGGCGCCAGCGGTGTTGGCGTCGGCGCGCGACTGGTGACAGCTGCGACGCCCG
ATGCATCTTGGGAGATGCCCTATAGCCCGGTCACGGTGAACATGTACGCCCTTGCAGCGGCAAGGCATATGTACGAGTTC
GGCACTACTTCCGAACAACTCGCATGGATCAAGGTGGCGGCTGCCACCCATGCGCAGCACAACCCGAATGCGATGCTCCG
CGACCTCGTTAGCGTCGAGGATGTGCTCGGCTCAGCTCTGATCTCTGACCCGCTGCATAAACTTGACTGCTGCGTTGTCA
GTGACGGTGGCGGCGCGCTTGTCGTAGCGCGACCCGAAATCGCCCGAAAGCTCAACCGTCCCATCGTGAAAGTACTGGGT
GCGGGCGAGACGATCAAAGGCCAACTGGGCGGGAACGTCGACCTCACCTATTCCGGGGCAGCGGTGTCGGGACCGGTCGC
CTTTGAAGAAGCCGGAATCAAGCCGTCTGACATCCAGTACGCATCAATCTACGACAGCTTCACCATCACCGTTCTGATGC
AGTTGGAAGACCTTGGCTTCTGCAAGAAAGGCGAAGGTGGCAAGTTCGTCGCTGATGGAAATCTGATCTCCGGCGTAGGC
AAGCTGCCCTTCAACACGGATGGCGGTGGCCTTTGCAACAACCACCCGGCAAACCGCGGTGGCATCACCAAAGTCATCGA
GGCAGTCCGTCAGTTGCGCGGGGAGGCACATCCCAAGGTGCAAGTTCCCAACTGCACTCTCGCGCTTGCTCAAGGTACCG
GCGGCCTCCTCGGTTCGCGCCACGGTAGCGCAACTCTCATCTTGGAAAGGGAATGA

Upstream 100 bases:

>100_bases
CGCCTTTGCATGAGCCATCGAAAACTGCCTCGCCGCTCATTTCATTATGGTTGAACCAATGATATCATCGACTACGGAGA
CTGACTCAACTGGAGTAGAC

Downstream 100 bases:

>100_bases
GCCATGACTACACCCCACGTTGATCGCCCTCTTGCTGCCCCAGTTGTTGACGCAAGCAACGAAAGCTACTGGCGCTATGC
GCGTGAAGGCATGCTCAGCT

Product: acetyl-CoA acetyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 390

Protein sequence:

>391_residues
MTIKGKACIVGAYEHPTRKAPDKTVAQLHAECAKGALEDAGLTLQDVDGYFCAGDAPGLGANSMADYLGLTNLRHVDTTD
TGGSAYLIHVSHAAQAIAAGKCNVALITLAGRPRTEGASGVGVGARLVTAATPDASWEMPYSPVTVNMYALAAARHMYEF
GTTSEQLAWIKVAAATHAQHNPNAMLRDLVSVEDVLGSALISDPLHKLDCCVVSDGGGALVVARPEIARKLNRPIVKVLG
AGETIKGQLGGNVDLTYSGAAVSGPVAFEEAGIKPSDIQYASIYDSFTITVLMQLEDLGFCKKGEGGKFVADGNLISGVG
KLPFNTDGGGLCNNHPANRGGITKVIEAVRQLRGEAHPKVQVPNCTLALAQGTGGLLGSRHGSATLILERE

Sequences:

>Translated_391_residues
MTIKGKACIVGAYEHPTRKAPDKTVAQLHAECAKGALEDAGLTLQDVDGYFCAGDAPGLGANSMADYLGLTNLRHVDTTD
TGGSAYLIHVSHAAQAIAAGKCNVALITLAGRPRTEGASGVGVGARLVTAATPDASWEMPYSPVTVNMYALAAARHMYEF
GTTSEQLAWIKVAAATHAQHNPNAMLRDLVSVEDVLGSALISDPLHKLDCCVVSDGGGALVVARPEIARKLNRPIVKVLG
AGETIKGQLGGNVDLTYSGAAVSGPVAFEEAGIKPSDIQYASIYDSFTITVLMQLEDLGFCKKGEGGKFVADGNLISGVG
KLPFNTDGGGLCNNHPANRGGITKVIEAVRQLRGEAHPKVQVPNCTLALAQGTGGLLGSRHGSATLILERE
>Mature_390_residues
TIKGKACIVGAYEHPTRKAPDKTVAQLHAECAKGALEDAGLTLQDVDGYFCAGDAPGLGANSMADYLGLTNLRHVDTTDT
GGSAYLIHVSHAAQAIAAGKCNVALITLAGRPRTEGASGVGVGARLVTAATPDASWEMPYSPVTVNMYALAAARHMYEFG
TTSEQLAWIKVAAATHAQHNPNAMLRDLVSVEDVLGSALISDPLHKLDCCVVSDGGGALVVARPEIARKLNRPIVKVLGA
GETIKGQLGGNVDLTYSGAAVSGPVAFEEAGIKPSDIQYASIYDSFTITVLMQLEDLGFCKKGEGGKFVADGNLISGVGK
LPFNTDGGGLCNNHPANRGGITKVIEAVRQLRGEAHPKVQVPNCTLALAQGTGGLLGSRHGSATLILERE

Specific function: Unknown

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI19923233, Length=377, Percent_Identity=28.6472148541114, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI302344760, Length=338, Percent_Identity=28.4023668639053, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI302344762, Length=241, Percent_Identity=31.1203319502075, Blast_Score=102, Evalue=9e-22,
Organism=Homo sapiens, GI302344767, Length=241, Percent_Identity=31.1203319502075, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI55956775, Length=203, Percent_Identity=29.5566502463054, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17537653, Length=236, Percent_Identity=29.2372881355932, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI19921506, Length=390, Percent_Identity=27.9487179487179, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24585051, Length=388, Percent_Identity=27.319587628866, Blast_Score=115, Evalue=5e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020617
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: NA

Molecular weight: Translated: 40506; Mature: 40374

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIKGKACIVGAYEHPTRKAPDKTVAQLHAECAKGALEDAGLTLQDVDGYFCAGDAPGLG
CCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCHHHCCCEEEECCCEEECCCCCCCC
ANSMADYLGLTNLRHVDTTDTGGSAYLIHVSHAAQAIAAGKCNVALITLAGRPRTEGASG
CHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCHHHHHHCCCCCEEEEEECCCCCCCCCCC
VGVGARLVTAATPDASWEMPYSPVTVNMYALAAARHMYEFGTTSEQLAWIKVAAATHAQH
CCCCEEEEEECCCCCCCCCCCCCEEEEHHHHHHHHHHHHCCCCCHHEEEEEEEEHHCCCC
NPNAMLRDLVSVEDVLGSALISDPLHKLDCCVVSDGGGALVVARPEIARKLNRPIVKVLG
CCHHHHHHHHHHHHHHHHHHHHCCHHHCEEEEEECCCCEEEEECHHHHHHHCCCCEEHHC
AGETIKGQLGGNVDLTYSGAAVSGPVAFEEAGIKPSDIQYASIYDSFTITVLMQLEDLGF
CCCEEEECCCCCEEEEECCCCCCCCCCHHHCCCCCCCEEEEEECCCEEEEEEEEEHHCCC
CKKGEGGKFVADGNLISGVGKLPFNTDGGGLCNNHPANRGGITKVIEAVRQLRGEAHPKV
CCCCCCCEEEECCCEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCE
QVPNCTLALAQGTGGLLGSRHGSATLILERE
ECCCEEEEEECCCCCCCCCCCCCEEEEEECC
>Mature Secondary Structure 
TIKGKACIVGAYEHPTRKAPDKTVAQLHAECAKGALEDAGLTLQDVDGYFCAGDAPGLG
CCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCHHHCCCEEEECCCEEECCCCCCCC
ANSMADYLGLTNLRHVDTTDTGGSAYLIHVSHAAQAIAAGKCNVALITLAGRPRTEGASG
CHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCHHHHHHCCCCCEEEEEECCCCCCCCCCC
VGVGARLVTAATPDASWEMPYSPVTVNMYALAAARHMYEFGTTSEQLAWIKVAAATHAQH
CCCCEEEEEECCCCCCCCCCCCCEEEEHHHHHHHHHHHHCCCCCHHEEEEEEEEHHCCCC
NPNAMLRDLVSVEDVLGSALISDPLHKLDCCVVSDGGGALVVARPEIARKLNRPIVKVLG
CCHHHHHHHHHHHHHHHHHHHHCCHHHCEEEEEECCCCEEEEECHHHHHHHCCCCEEHHC
AGETIKGQLGGNVDLTYSGAAVSGPVAFEEAGIKPSDIQYASIYDSFTITVLMQLEDLGF
CCCEEEECCCCCEEEEECCCCCCCCCCHHHCCCCCCCEEEEEECCCEEEEEEEEEHHCCC
CKKGEGGKFVADGNLISGVGKLPFNTDGGGLCNNHPANRGGITKVIEAVRQLRGEAHPKV
CCCCCCCEEEECCCEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCE
QVPNCTLALAQGTGGLLGSRHGSATLILERE
ECCCEEEEEECCCCCCCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]