BacMap

Definition	Cupriavidus metallidurans CH34 megaplasmid, complete sequence.
Accession	NC_007974
Length	2,580,084

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The map label for this gene is ucpA [C]

Identifier: 94314298

GI number: 94314298

Start: 2105338

End: 2106147

Strand: Reverse

Name: ucpA [C]

Synonym: Rmet_5379

Alternate gene names: 94314298

Gene position: 2106147-2105338 (Counterclockwise)

Preceding gene: 94314299

Following gene: 94314290

Centisome position: 81.63

GC content: 68.15

Gene sequence:

>810_bases
ATGAACGCGCTGCCGCTCAGTCTGGCGGATCGCACCGTGTTTGTGGCGGGCGGTGGATCGGCGGGCCCCGGCTGGAGCAT
CGGGCGCGCCGCCAGCGTGACCTATGCCCGGCTTGGCGCCCGCGTCTGCGTGGTGGACCGCGACGCCGCCTCGGCTGCGG
AGACGACGGCGCTGATTCGGGCCGAGGGTGGCGCGGCGGAGACCTTCGTCGGCGACGTGGCGGAAGAGGCGGAGATCGCG
CGCCTGTTCGCGGAGGCGCGCGAACACTTCGGCCCCATCGATGTGCTGCATCACAACGTTGGCATCGGCAAGACCGGCGG
GGTTCTGGACACCGATGTGCGGGATTTCGATGCGGCCCACAACGTGAACGTGCGAAGCCTGCTGCTGGCGTCGCAGCAGG
TGCTGCCGTCAATGGTCGAGCGGGGCCGGGGTGCCATCGTCACGGTTTCCTCGGTGGCGGGGCTACGCTATATCGGCTAT
CCGCACCTGTCGTACAGCGTCAGCAAGGCCGCGCTGATCCAGTTCACGCGGATGATCGCGCAGCAGTACGCGGGCAGCGG
CATCCGTGCAAATTGCGTGGTGCCGGGTTTGATCGACACGCCACGCATCGCCCATACCGTGGCGAAGCAGTTCTCGGCGG
ACAGTCTCGACGACGCCCGCGCGGCGCGTGCGAGACAGGTGCCGATGCAGCGGATGGGCACCGCGTGGGACGTGGCACAC
GCCTGTGCGTTCCTGGCGTCGGATGCAGCGGCCTACATTACCGGCACCGAGCTGGTGGTCGATGGAGGGATAACGGGGAA
GTACGCATAG

Upstream 100 bases:

>100_bases
ATATCGTCGAGGAGCAGCAGAGCCCGTCGGGACGCTATATCTGGGACGTGGTCGAGGAGGCCATCCCGTACGTCGGCAAC
GCGCCGCACGGAGACCACGC

Downstream 100 bases:

>100_bases
GTGCGTCCCCCATGGGCGCCGCTCAGCTGCTCAGCCGCTCAGCCGAATCAGCCAAACACCACCATCGGCACGCCCCGGTG
AACTGGCGATTCCATGACGG

Product: short-chain dehydrogenase; putative 3-oxoacyl-(acyl-carrier-protein) reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MNALPLSLADRTVFVAGGGSAGPGWSIGRAASVTYARLGARVCVVDRDAASAAETTALIRAEGGAAETFVGDVAEEAEIA
RLFAEAREHFGPIDVLHHNVGIGKTGGVLDTDVRDFDAAHNVNVRSLLLASQQVLPSMVERGRGAIVTVSSVAGLRYIGY
PHLSYSVSKAALIQFTRMIAQQYAGSGIRANCVVPGLIDTPRIAHTVAKQFSADSLDDARAARARQVPMQRMGTAWDVAH
ACAFLASDAAAYITGTELVVDGGITGKYA

Sequences:

>Translated_269_residues
MNALPLSLADRTVFVAGGGSAGPGWSIGRAASVTYARLGARVCVVDRDAASAAETTALIRAEGGAAETFVGDVAEEAEIA
RLFAEAREHFGPIDVLHHNVGIGKTGGVLDTDVRDFDAAHNVNVRSLLLASQQVLPSMVERGRGAIVTVSSVAGLRYIGY
PHLSYSVSKAALIQFTRMIAQQYAGSGIRANCVVPGLIDTPRIAHTVAKQFSADSLDDARAARARQVPMQRMGTAWDVAH
ACAFLASDAAAYITGTELVVDGGITGKYA
>Mature_269_residues
MNALPLSLADRTVFVAGGGSAGPGWSIGRAASVTYARLGARVCVVDRDAASAAETTALIRAEGGAAETFVGDVAEEAEIA
RLFAEAREHFGPIDVLHHNVGIGKTGGVLDTDVRDFDAAHNVNVRSLLLASQQVLPSMVERGRGAIVTVSSVAGLRYIGY
PHLSYSVSKAALIQFTRMIAQQYAGSGIRANCVVPGLIDTPRIAHTVAKQFSADSLDDARAARARQVPMQRMGTAWDVAH
ACAFLASDAAAYITGTELVVDGGITGKYA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI66933014, Length=229, Percent_Identity=34.4978165938865, Blast_Score=123, Evalue=1e-28,
Organism=Homo sapiens, GI40254992, Length=248, Percent_Identity=32.6612903225806, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI32483357, Length=239, Percent_Identity=32.2175732217573, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI5031737, Length=256, Percent_Identity=33.984375, Blast_Score=105, Evalue=3e-23,
Organism=Homo sapiens, GI15277342, Length=252, Percent_Identity=33.3333333333333, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI33667109, Length=252, Percent_Identity=33.7301587301587, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI126723750, Length=249, Percent_Identity=30.1204819277108, Blast_Score=94, Evalue=9e-20,
Organism=Homo sapiens, GI210032110, Length=198, Percent_Identity=28.7878787878788, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI7705925, Length=262, Percent_Identity=29.0076335877863, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI142976729, Length=183, Percent_Identity=26.775956284153, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI59889578, Length=231, Percent_Identity=28.1385281385281, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI126723191, Length=169, Percent_Identity=31.3609467455621, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI40254986, Length=199, Percent_Identity=27.6381909547739, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI19923817, Length=262, Percent_Identity=25.1908396946565, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI109715829, Length=199, Percent_Identity=27.1356783919598, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI31542939, Length=196, Percent_Identity=25.5102040816327, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI87082100, Length=239, Percent_Identity=33.8912133891213, Blast_Score=137, Evalue=8e-34,
Organism=Escherichia coli, GI1787335, Length=243, Percent_Identity=33.3333333333333, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1789378, Length=260, Percent_Identity=31.5384615384615, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI2367175, Length=254, Percent_Identity=31.8897637795276, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1787905, Length=242, Percent_Identity=32.2314049586777, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI87082160, Length=259, Percent_Identity=28.1853281853282, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1789208, Length=222, Percent_Identity=28.3783783783784, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1786812, Length=273, Percent_Identity=30.4029304029304, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790717, Length=266, Percent_Identity=27.0676691729323, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1789057, Length=259, Percent_Identity=29.3436293436293, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1788459, Length=243, Percent_Identity=27.5720164609054, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI2367365, Length=172, Percent_Identity=30.8139534883721, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1787545, Length=204, Percent_Identity=30.3921568627451, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17555706, Length=258, Percent_Identity=32.5581395348837, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17559104, Length=254, Percent_Identity=33.0708661417323, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI71994604, Length=257, Percent_Identity=33.4630350194552, Blast_Score=107, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI71994600, Length=260, Percent_Identity=33.0769230769231, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17544670, Length=263, Percent_Identity=30.0380228136882, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17562910, Length=270, Percent_Identity=30, Blast_Score=101, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17560150, Length=252, Percent_Identity=31.3492063492063, Blast_Score=101, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI25147288, Length=267, Percent_Identity=31.0861423220974, Blast_Score=100, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI193204405, Length=261, Percent_Identity=29.8850574712644, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17531453, Length=250, Percent_Identity=30.8, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17562908, Length=255, Percent_Identity=32.156862745098, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17538480, Length=255, Percent_Identity=29.4117647058824, Blast_Score=97, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17551412, Length=280, Percent_Identity=28.5714285714286, Blast_Score=97, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17562906, Length=262, Percent_Identity=30.5343511450382, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17560220, Length=261, Percent_Identity=31.0344827586207, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17560332, Length=258, Percent_Identity=29.8449612403101, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17562990, Length=250, Percent_Identity=29.6, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17562904, Length=266, Percent_Identity=27.8195488721804, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI115534694, Length=265, Percent_Identity=30.5660377358491, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17560676, Length=263, Percent_Identity=28.1368821292776, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17564282, Length=198, Percent_Identity=31.3131313131313, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI72000259, Length=262, Percent_Identity=29.0076335877863, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17561402, Length=231, Percent_Identity=28.1385281385281, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17538486, Length=253, Percent_Identity=30.8300395256917, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17563726, Length=265, Percent_Identity=26.7924528301887, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17565030, Length=257, Percent_Identity=30.7392996108949, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17536025, Length=264, Percent_Identity=28.030303030303, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193203117, Length=198, Percent_Identity=28.7878787878788, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI193203115, Length=222, Percent_Identity=26.5765765765766, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17561272, Length=245, Percent_Identity=26.9387755102041, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=208, Percent_Identity=26.9230769230769, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17567345, Length=208, Percent_Identity=25.9615384615385, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17508651, Length=210, Percent_Identity=28.0952380952381, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17536651, Length=258, Percent_Identity=24.8062015503876, Blast_Score=68, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6324126, Length=271, Percent_Identity=25.4612546125461, Blast_Score=76, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6322861, Length=199, Percent_Identity=26.6331658291457, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI23397609, Length=261, Percent_Identity=38.3141762452107, Blast_Score=143, Evalue=1e-34,
Organism=Drosophila melanogaster, GI28571526, Length=262, Percent_Identity=38.5496183206107, Blast_Score=134, Evalue=8e-32,
Organism=Drosophila melanogaster, GI21357041, Length=260, Percent_Identity=37.3076923076923, Blast_Score=132, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24644339, Length=268, Percent_Identity=33.5820895522388, Blast_Score=129, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24639444, Length=262, Percent_Identity=32.824427480916, Blast_Score=121, Evalue=5e-28,
Organism=Drosophila melanogaster, GI21355319, Length=245, Percent_Identity=33.8775510204082, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24644337, Length=232, Percent_Identity=34.051724137931, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24640492, Length=185, Percent_Identity=29.1891891891892, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI221510726, Length=166, Percent_Identity=28.9156626506024, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24581726, Length=203, Percent_Identity=27.0935960591133, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI21357673, Length=200, Percent_Identity=27.5, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI281364892, Length=217, Percent_Identity=30.4147465437788, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24649181, Length=211, Percent_Identity=27.4881516587678, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI21355631, Length=146, Percent_Identity=26.7123287671233, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24643142, Length=173, Percent_Identity=27.1676300578035, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI18859837, Length=183, Percent_Identity=28.4153005464481, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 28066; Mature: 28066

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNALPLSLADRTVFVAGGGSAGPGWSIGRAASVTYARLGARVCVVDRDAASAAETTALIR
CCCCCCEECCCEEEEECCCCCCCCCCCCCHHHHHHHHHCCEEEEEECCCHHHHHHEEEEE
AEGGAAETFVGDVAEEAEIARLFAEAREHFGPIDVLHHNVGIGKTGGVLDTDVRDFDAAH
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHC
NVNVRSLLLASQQVLPSMVERGRGAIVTVSSVAGLRYIGYPHLSYSVSKAALIQFTRMIA
CCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHH
QQYAGSGIRANCVVPGLIDTPRIAHTVAKQFSADSLDDARAARARQVPMQRMGTAWDVAH
HHHCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHCCCHHHHHH
ACAFLASDAAAYITGTELVVDGGITGKYA
HHHHHHCCCCEEEECCEEEEECCCCCCCC
>Mature Secondary Structure
MNALPLSLADRTVFVAGGGSAGPGWSIGRAASVTYARLGARVCVVDRDAASAAETTALIR
CCCCCCEECCCEEEEECCCCCCCCCCCCCHHHHHHHHHCCEEEEEECCCHHHHHHEEEEE
AEGGAAETFVGDVAEEAEIARLFAEAREHFGPIDVLHHNVGIGKTGGVLDTDVRDFDAAH
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHC
NVNVRSLLLASQQVLPSMVERGRGAIVTVSSVAGLRYIGYPHLSYSVSKAALIQFTRMIA
CCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHH
QQYAGSGIRANCVVPGLIDTPRIAHTVAKQFSADSLDDARAARARQVPMQRMGTAWDVAH
HHHCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHCCCHHHHHH
ACAFLASDAAAYITGTELVVDGGITGKYA
HHHHHHCCCCEEEECCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]