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The map label for this gene is zniR [H]

Identifier: 94314242

GI number: 94314242

Start: 2033310

End: 2033930

Strand: Direct

Name: zniR [H]

Synonym: Rmet_5323

Alternate gene names: 94314242

Gene position: 2033310-2033930 (Clockwise)

Preceding gene: 94314240

Following gene: 94314244

Centisome position: 78.81

GC content: 62.96

Gene sequence:

>621_bases
ATGGTCACATCCGCAGACAATACTCCCCACCAGATTCTATGCATCGAAGACGATGCAGAGACCGCTACGCTCATCGCGGA
AGAACTGACCGAGCGAGGCTTCGCCGTGACCGTCGCCCATGACGGCCAGGAAGGCTTTGCCGCCATTCTGCGCATGCCAC
CCGATCTTGTCCTGTGCGATGTGGGCATGCCTGTCATGGACGGCTTCGAGGTGCTCGCGAAACTGCGCGCGCTGGCCCCG
CGCTATGCTGAAGTGCCTTTCGTTTTCCTAACCGCACTGGCCCAGCGCGATGCCGAACTCAAGGGACGCCGTCTGGGCGC
GGACGACTACGTCGCCAAACCCGTGGATTTTGACATCCTTGAGAGCATTATCGAAGCGCGGCTGTCGCGCGCTGTCAAAC
CGCAACAACGCACCCCGCAGAACGTCACGCTGAGCGAGCGCGAGATCGAGGCGCTTTCATGGTCCGCGCGCGGCAAGACG
TCGGGCGAGATCGCGACGATCCTGGGGCTGTCGAAGCGGACGGTCGATTTCCATATCGACCGCGCCAGGGAGAAACTGGG
CGTGGCCACGCGGGTCGAAGCCGTGGTGCGCGCGGCCACCGAGGGGTTCATCAAACCGTAG

Upstream 100 bases:

>100_bases
TCCCTCTGCGCTAGACAAGTGGCGCATACATTACCTTGAAGTTGCAAGATGCCGTTCGATTGACGGGTTGCGGCCCGCTC
CCCTACAGTAGTGCCCCTAC

Downstream 100 bases:

>100_bases
GCGCCGATCAGTCGTCGTCGTGCCAGCGGTGCCACTCACGACGGCGGTACTCGTGCTCGCGCCATTCGTGCTCGCGCCAC
TCCCGGCCGCGCCAGCCATC

Product: transcriptional regulator two component heavy metal regulatory response ZniR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MVTSADNTPHQILCIEDDAETATLIAEELTERGFAVTVAHDGQEGFAAILRMPPDLVLCDVGMPVMDGFEVLAKLRALAP
RYAEVPFVFLTALAQRDAELKGRRLGADDYVAKPVDFDILESIIEARLSRAVKPQQRTPQNVTLSEREIEALSWSARGKT
SGEIATILGLSKRTVDFHIDRAREKLGVATRVEAVVRAATEGFIKP

Sequences:

>Translated_206_residues
MVTSADNTPHQILCIEDDAETATLIAEELTERGFAVTVAHDGQEGFAAILRMPPDLVLCDVGMPVMDGFEVLAKLRALAP
RYAEVPFVFLTALAQRDAELKGRRLGADDYVAKPVDFDILESIIEARLSRAVKPQQRTPQNVTLSEREIEALSWSARGKT
SGEIATILGLSKRTVDFHIDRAREKLGVATRVEAVVRAATEGFIKP
>Mature_206_residues
MVTSADNTPHQILCIEDDAETATLIAEELTERGFAVTVAHDGQEGFAAILRMPPDLVLCDVGMPVMDGFEVLAKLRALAP
RYAEVPFVFLTALAQRDAELKGRRLGADDYVAKPVDFDILESIIEARLSRAVKPQQRTPQNVTLSEREIEALSWSARGKT
SGEIATILGLSKRTVDFHIDRAREKLGVATRVEAVVRAATEGFIKP

Specific function: Member of the two-component regulatory system rprX/rprY [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=128, Percent_Identity=32.8125, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI1786784, Length=200, Percent_Identity=26.5, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788394, Length=227, Percent_Identity=27.7533039647577, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1790299, Length=134, Percent_Identity=31.3432835820896, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI87082012, Length=118, Percent_Identity=32.2033898305085, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1788550, Length=181, Percent_Identity=28.7292817679558, Blast_Score=70, Evalue=8e-14,
Organism=Escherichia coli, GI1790860, Length=103, Percent_Identity=37.8640776699029, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1789402, Length=123, Percent_Identity=36.5853658536585, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI145693157, Length=129, Percent_Identity=27.906976744186, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI145693140, Length=104, Percent_Identity=37.5, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI2367329, Length=143, Percent_Identity=33.5664335664336, Blast_Score=60, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 22556; Mature: 22556

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTSADNTPHQILCIEDDAETATLIAEELTERGFAVTVAHDGQEGFAAILRMPPDLVLCD
CCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHCCCCEEEEC
VGMPVMDGFEVLAKLRALAPRYAEVPFVFLTALAQRDAELKGRRLGADDYVAKPVDFDIL
CCCCHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHCHHHCCCCCCCCCCCCCCCCHHHH
ESIIEARLSRAVKPQQRTPQNVTLSEREIEALSWSARGKTSGEIATILGLSKRTVDFHID
HHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHH
RAREKLGVATRVEAVVRAATEGFIKP
HHHHHHCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MVTSADNTPHQILCIEDDAETATLIAEELTERGFAVTVAHDGQEGFAAILRMPPDLVLCD
CCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHCCCCEEEEC
VGMPVMDGFEVLAKLRALAPRYAEVPFVFLTALAQRDAELKGRRLGADDYVAKPVDFDIL
CCCCHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHCHHHCCCCCCCCCCCCCCCCHHHH
ESIIEARLSRAVKPQQRTPQNVTLSEREIEALSWSARGKTSGEIATILGLSKRTVDFHID
HHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHH
RAREKLGVATRVEAVVRAATEGFIKP
HHHHHHCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8469117 [H]