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The map label for this gene is zniC [H]

Identifier: 94314240

GI number: 94314240

Start: 2030065

End: 2031621

Strand: Direct

Name: zniC [H]

Synonym: Rmet_5321

Alternate gene names: 94314240

Gene position: 2030065-2031621 (Clockwise)

Preceding gene: 94314236

Following gene: 94314242

Centisome position: 78.68

GC content: 66.47

Gene sequence:

>1557_bases
ATGCTGCCAGATCACCGCAGCCCTTCCATTCGTTCGAGAATCCCATTCGCCGGCACGGCTTGCGCCCTGGCCGTTTGCGG
CGTTCTGACGGCGTGCGCCGTCGGCCCCAATTTCCAGACGCCCAAGGCGCCTGATGCCACCGCGTACACACCCAAGCCGC
TGCCCACCGAGACGGCATCCGCGCCGGTGCAAGGCGGCGAAGCCCAGCGCTTCGTGGAAGGCATGCAGATCCCCGAGCAG
TGGTGGAGCATGTTGCACTCGGAAAAGCTCGACCGCTTTATCGCGGCAGCGATGAAGGCCAATCCGACGGTGACGGCCGC
GCAAGCAGCGCTGCGGCAGGCCCAGGCGCAAGTGCGCGCGCAGCAGGGCTTCTTCTTCCCGACCATCTCGGGTTCCTATT
CGCCATCGCGGCAGCGCAATGCGGTAGGAACGATCTCGCCGACGCTGACGTCTGGCGATCCGCTCTTCAACCTGCACACG
GCGGAACTGTCGATCAGCTACGCGCCCGATGTGTTCGGCCTGAACCGCCGACGGGTGGAATCGCTGCAGGCGCTCGAGGA
TGCGCAGCGTTTCGAGGTGGAGGCTACCTACCTGACGCTGGCATCGAACATCAGCCTGGCCGCTATCGAGGAAGCTTCGT
TGCGCGCCCAGATCGACGCGCAACAACGCATCGTCGCCATCGAGACCAAGCTGTACAACCTGCTGCAGAAGCAATTCACG
CTCGGGTTCGTCAGCGGTCTCGAAGTGGCCGCGGCCCGGGCCCAGCTTGCGCAAGCCGAGCAGGCATTGCCAGGACTGCG
CAAGCAACTGGCCCTGCAGCGCGACCTGCTGGCTGCGCTGGCCGGCAAGCTGCCGGCCGATCCGCTCGACGCCGAGTTCA
CGTTCGACGATTTCAAGTTGCCGGCGGAACTTCCGGTGTCGCTGCCGTCTGAACTGGTGCGGCAGCGCCCGGACGTGCGC
GCGGCCGAAGCACAACTGCATTCGGCCACGGCGGAAGTCGGCGTGGCTATCGCCAACATGCTGCCGCAGCTCACCATCAC
TGGCTCATACGGCGGCACGGCCACCGTGTTCAACCAGATGTTCAGCGCCGGCAACGTCTTCTGGAGCCTGGCGGGCAACG
TCGCGCAAACCTTCTTCGCGGGCGGCACGATGCTGGCGCTCAAGCACGGCGCCGATGCCGCGCTCGTGCAGGCGGAGGCC
CAGTACCGCAGCACCGTCATCAACGCGTTCCAGAACGTGGCCGATACGCTGCACGCGATCGACGCCGATGCGGAAACGCT
GCGTGCGGCCATCACCTCGGAGCAGGCCGCGCGCACGACGCTGGAGATCACCGAGAAGCAACTGTCGAGCGGCTACGTCA
ATGTGCTGGCCGTGCTCAACGCCGAACAGACGATGCGCACGGCCACGCAGGCCACGGCACAGGCGCAGGCCGCGCGCTTC
ACGGATACCGTGGCGCTCTACCAGTCTCTGGGTGGCGGCTGGTGGAATCGCCAGGCCGAAGGTACGCAGGTGGGTGACGC
GGGCAAGCCGGCCCGCGCCGAAGTCGCTACGCGCTGA

Upstream 100 bases:

>100_bases
TTAATGACAGTGGCCTGGCCGGCGCATCGCTCATAGAATCCGCCCAGCGCTACCAATAGCTCTACCAACAGCACCAGCCA
TCGCTTTGAGGTCACGGCCC

Downstream 100 bases:

>100_bases
GCGGCGCTGGCGCTGGCGCTTCTGGCAGCCTGAGCAAGAAGCGCGAGCCCGTGCCTTCCGCGCTTCGCACCGACACCGTG
CCGCCATGCAATTCGGCGGC

Product: heavy metal cation tricomponent efflux outer membrane porin ZniC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 518; Mature: 518

Protein sequence:

>518_residues
MLPDHRSPSIRSRIPFAGTACALAVCGVLTACAVGPNFQTPKAPDATAYTPKPLPTETASAPVQGGEAQRFVEGMQIPEQ
WWSMLHSEKLDRFIAAAMKANPTVTAAQAALRQAQAQVRAQQGFFFPTISGSYSPSRQRNAVGTISPTLTSGDPLFNLHT
AELSISYAPDVFGLNRRRVESLQALEDAQRFEVEATYLTLASNISLAAIEEASLRAQIDAQQRIVAIETKLYNLLQKQFT
LGFVSGLEVAAARAQLAQAEQALPGLRKQLALQRDLLAALAGKLPADPLDAEFTFDDFKLPAELPVSLPSELVRQRPDVR
AAEAQLHSATAEVGVAIANMLPQLTITGSYGGTATVFNQMFSAGNVFWSLAGNVAQTFFAGGTMLALKHGADAALVQAEA
QYRSTVINAFQNVADTLHAIDADAETLRAAITSEQAARTTLEITEKQLSSGYVNVLAVLNAEQTMRTATQATAQAQAARF
TDTVALYQSLGGGWWNRQAEGTQVGDAGKPARAEVATR

Sequences:

>Translated_518_residues
MLPDHRSPSIRSRIPFAGTACALAVCGVLTACAVGPNFQTPKAPDATAYTPKPLPTETASAPVQGGEAQRFVEGMQIPEQ
WWSMLHSEKLDRFIAAAMKANPTVTAAQAALRQAQAQVRAQQGFFFPTISGSYSPSRQRNAVGTISPTLTSGDPLFNLHT
AELSISYAPDVFGLNRRRVESLQALEDAQRFEVEATYLTLASNISLAAIEEASLRAQIDAQQRIVAIETKLYNLLQKQFT
LGFVSGLEVAAARAQLAQAEQALPGLRKQLALQRDLLAALAGKLPADPLDAEFTFDDFKLPAELPVSLPSELVRQRPDVR
AAEAQLHSATAEVGVAIANMLPQLTITGSYGGTATVFNQMFSAGNVFWSLAGNVAQTFFAGGTMLALKHGADAALVQAEA
QYRSTVINAFQNVADTLHAIDADAETLRAAITSEQAARTTLEITEKQLSSGYVNVLAVLNAEQTMRTATQATAQAQAARF
TDTVALYQSLGGGWWNRQAEGTQVGDAGKPARAEVATR
>Mature_518_residues
MLPDHRSPSIRSRIPFAGTACALAVCGVLTACAVGPNFQTPKAPDATAYTPKPLPTETASAPVQGGEAQRFVEGMQIPEQ
WWSMLHSEKLDRFIAAAMKANPTVTAAQAALRQAQAQVRAQQGFFFPTISGSYSPSRQRNAVGTISPTLTSGDPLFNLHT
AELSISYAPDVFGLNRRRVESLQALEDAQRFEVEATYLTLASNISLAAIEEASLRAQIDAQQRIVAIETKLYNLLQKQFT
LGFVSGLEVAAARAQLAQAEQALPGLRKQLALQRDLLAALAGKLPADPLDAEFTFDDFKLPAELPVSLPSELVRQRPDVR
AAEAQLHSATAEVGVAIANMLPQLTITGSYGGTATVFNQMFSAGNVFWSLAGNVAQTFFAGGTMLALKHGADAALVQAEA
QYRSTVINAFQNVADTLHAIDADAETLRAAITSEQAARTTLEITEKQLSSGYVNVLAVLNAEQTMRTATQATAQAQAARF
TDTVALYQSLGGGWWNRQAEGTQVGDAGKPARAEVATR

Specific function: The outer membrane component of an antibiotic efflux pump. Confers resistance to numerous structurally unrelated antibiotics such as carbenicillin, chloramphenicol, erythromycin, novobiocin, streptomycin and tetracycline. Is not involved in organic solven

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=489, Percent_Identity=24.3353783231084, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI2367348, Length=443, Percent_Identity=21.6704288939052, Blast_Score=66, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 55300; Mature: 55300

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPDHRSPSIRSRIPFAGTACALAVCGVLTACAVGPNFQTPKAPDATAYTPKPLPTETAS
CCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
APVQGGEAQRFVEGMQIPEQWWSMLHSEKLDRFIAAAMKANPTVTAAQAALRQAQAQVRA
CCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
QQGFFFPTISGSYSPSRQRNAVGTISPTLTSGDPLFNLHTAELSISYAPDVFGLNRRRVE
HCCCEEEECCCCCCCCHHCCCCCCCCCCCCCCCCEEEEEEEEEEEEECCCCCCCCHHHHH
SLQALEDAQRFEVEATYLTLASNISLAAIEEASLRAQIDAQQRIVAIETKLYNLLQKQFT
HHHHHHHHHHHEEEEEEEEEECCCCEEEEHHHHHHHHHCHHHHEEHHHHHHHHHHHHHHH
LGFVSGLEVAAARAQLAQAEQALPGLRKQLALQRDLLAALAGKLPADPLDAEFTFDDFKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCC
PAELPVSLPSELVRQRPDVRAAEAQLHSATAEVGVAIANMLPQLTITGSYGGTATVFNQM
CCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHH
FSAGNVFWSLAGNVAQTFFAGGTMLALKHGADAALVQAEAQYRSTVINAFQNVADTLHAI
HHCCCHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DADAETLRAAITSEQAARTTLEITEKQLSSGYVNVLAVLNAEQTMRTATQATAQAQAARF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHCHHHHHHHHHHHHHHHHHHHH
TDTVALYQSLGGGWWNRQAEGTQVGDAGKPARAEVATR
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLPDHRSPSIRSRIPFAGTACALAVCGVLTACAVGPNFQTPKAPDATAYTPKPLPTETAS
CCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
APVQGGEAQRFVEGMQIPEQWWSMLHSEKLDRFIAAAMKANPTVTAAQAALRQAQAQVRA
CCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
QQGFFFPTISGSYSPSRQRNAVGTISPTLTSGDPLFNLHTAELSISYAPDVFGLNRRRVE
HCCCEEEECCCCCCCCHHCCCCCCCCCCCCCCCCEEEEEEEEEEEEECCCCCCCCHHHHH
SLQALEDAQRFEVEATYLTLASNISLAAIEEASLRAQIDAQQRIVAIETKLYNLLQKQFT
HHHHHHHHHHHEEEEEEEEEECCCCEEEEHHHHHHHHHCHHHHEEHHHHHHHHHHHHHHH
LGFVSGLEVAAARAQLAQAEQALPGLRKQLALQRDLLAALAGKLPADPLDAEFTFDDFKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCC
PAELPVSLPSELVRQRPDVRAAEAQLHSATAEVGVAIANMLPQLTITGSYGGTATVFNQM
CCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHH
FSAGNVFWSLAGNVAQTFFAGGTMLALKHGADAALVQAEAQYRSTVINAFQNVADTLHAI
HHCCCHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DADAETLRAAITSEQAARTTLEITEKQLSSGYVNVLAVLNAEQTMRTATQATAQAQAARF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHCHHHHHHHHHHHHHHHHHHHH
TDTVALYQSLGGGWWNRQAEGTQVGDAGKPARAEVATR
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11160799 [H]