| Definition | Cupriavidus metallidurans CH34 megaplasmid, complete sequence. |
|---|---|
| Accession | NC_007974 |
| Length | 2,580,084 |
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The map label for this gene is fabG [H]
Identifier: 94314209
GI number: 94314209
Start: 1991497
End: 1992321
Strand: Reverse
Name: fabG [H]
Synonym: Rmet_5290
Alternate gene names: 94314209
Gene position: 1992321-1991497 (Counterclockwise)
Preceding gene: 94314210
Following gene: 94314203
Centisome position: 77.22
GC content: 62.91
Gene sequence:
>825_bases ATGCCGTCGCGTTCTGACCGGCCGATCTTCCCCAAGGGCTCACGAACAGTCTCGCCTGACTTATCCAAGGAAACGCTTAT GTCTCATCCTGTTGTCTTGATTACCGGCGCGACCGCCGGCATCGGCCGTGCGACGGCGCTTGCCTTTGCAGCCAAGGGCG CGCGGCTGGTCTGTTCCGGGCGGAATGCCGCAGCCGGAGACGCCCTCATCTCCGAACTTCGGGAGATGGGCGCGGAAGCA GACTTCCTGGCGGCCGATGTCAGCCGTGAGGACGATGTCATGCGTCTTGTCAGTCATGCCGTCGAGCGCTTTGGCTGCCT CGATATCGCAGTGAACAGTGCCGGGACGGAGGGCACACCGGGGTCGATCGTCGAGCAGACCGTCCAGTCGTACGCGACGA CGTTCGATGCGAACGTCCTTGGGACGTTCCTTTGCATGAAGCACGAGCTGAAAGCAATGATCGGGCAACAGCGCGGAGTC GTTGTCAATCTGTCGTCCACGATGGGCAGTCGCGGCAATCCGCGCAATCCGATGTATGTGGCGAGCAAGCACGCAATCGA GGGCCTGACCAAGTCCGCGGCCCTTGACGTCATCCAGGCGAATGTCCGCGTCAATGCCGTGGCGCCGGGCCCGATTGAAA CGGCCATGCTCGGGCGCATTGCCGGTGGCGCGGATCGGCTTGCCTCCGTCGCTGCGACGATCCCTGCCGGGCGCGTTGGC ACCCCGGAAGAGGTCGCCGATGCGATTCTGTTCCTGGCATCCGATCAATCGACGTACATCACGGGGCAGATCCTTCATGT GAACGGTGGGAAGACCGCCGGGTAA
Upstream 100 bases:
>100_bases GCCGACCAGGTCAAACGCGTGGTTGGCATTCTGAGGTCGCTGAACCTCGACGTGGCATCGCCGGACGAGGCCCGCGACAT GCTGCAGCTAAAGGGCCGCG
Downstream 100 bases:
>100_bases GTCGGCGGTGTCCCGGGGGCGCGGTCAAGGGCCCCGGGAATGTCGGGGCTGCGGCGCGCGCTGCAGCGATCAGGAGCGAT CAGTACCTGATGGTGCCGGG
Product: 3-oxoacyl-(acyl-carrier-protein) reductase
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 274; Mature: 273
Protein sequence:
>274_residues MPSRSDRPIFPKGSRTVSPDLSKETLMSHPVVLITGATAGIGRATALAFAAKGARLVCSGRNAAAGDALISELREMGAEA DFLAADVSREDDVMRLVSHAVERFGCLDIAVNSAGTEGTPGSIVEQTVQSYATTFDANVLGTFLCMKHELKAMIGQQRGV VVNLSSTMGSRGNPRNPMYVASKHAIEGLTKSAALDVIQANVRVNAVAPGPIETAMLGRIAGGADRLASVAATIPAGRVG TPEEVADAILFLASDQSTYITGQILHVNGGKTAG
Sequences:
>Translated_274_residues MPSRSDRPIFPKGSRTVSPDLSKETLMSHPVVLITGATAGIGRATALAFAAKGARLVCSGRNAAAGDALISELREMGAEA DFLAADVSREDDVMRLVSHAVERFGCLDIAVNSAGTEGTPGSIVEQTVQSYATTFDANVLGTFLCMKHELKAMIGQQRGV VVNLSSTMGSRGNPRNPMYVASKHAIEGLTKSAALDVIQANVRVNAVAPGPIETAMLGRIAGGADRLASVAATIPAGRVG TPEEVADAILFLASDQSTYITGQILHVNGGKTAG >Mature_273_residues PSRSDRPIFPKGSRTVSPDLSKETLMSHPVVLITGATAGIGRATALAFAAKGARLVCSGRNAAAGDALISELREMGAEAD FLAADVSREDDVMRLVSHAVERFGCLDIAVNSAGTEGTPGSIVEQTVQSYATTFDANVLGTFLCMKHELKAMIGQQRGVV VNLSSTMGSRGNPRNPMYVASKHAIEGLTKSAALDVIQANVRVNAVAPGPIETAMLGRIAGGADRLASVAATIPAGRVGT PEEVADAILFLASDQSTYITGQILHVNGGKTAG
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI59889578, Length=231, Percent_Identity=38.0952380952381, Blast_Score=125, Evalue=3e-29, Organism=Homo sapiens, GI40254992, Length=246, Percent_Identity=34.5528455284553, Blast_Score=124, Evalue=8e-29, Organism=Homo sapiens, GI32483357, Length=256, Percent_Identity=32.8125, Blast_Score=119, Evalue=3e-27, Organism=Homo sapiens, GI10190704, Length=267, Percent_Identity=29.5880149812734, Blast_Score=105, Evalue=5e-23, Organism=Homo sapiens, GI15277342, Length=251, Percent_Identity=32.6693227091633, Blast_Score=98, Evalue=7e-21, Organism=Homo sapiens, GI5031737, Length=260, Percent_Identity=29.6153846153846, Blast_Score=97, Evalue=1e-20, Organism=Homo sapiens, GI31542939, Length=194, Percent_Identity=35.0515463917526, Blast_Score=97, Evalue=2e-20, Organism=Homo sapiens, GI20149619, Length=234, Percent_Identity=30.7692307692308, Blast_Score=97, Evalue=2e-20, Organism=Homo sapiens, GI19923817, Length=271, Percent_Identity=27.6752767527675, Blast_Score=96, Evalue=3e-20, Organism=Homo sapiens, GI66933014, Length=246, Percent_Identity=33.739837398374, Blast_Score=96, Evalue=5e-20, Organism=Homo sapiens, GI7705925, Length=243, Percent_Identity=32.0987654320988, Blast_Score=94, Evalue=2e-19, Organism=Homo sapiens, GI126723750, Length=262, Percent_Identity=27.4809160305344, Blast_Score=93, Evalue=3e-19, Organism=Homo sapiens, GI109715829, Length=234, Percent_Identity=26.9230769230769, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI4758504, Length=250, Percent_Identity=28.8, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI33667109, Length=202, Percent_Identity=31.6831683168317, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI4504505, Length=188, Percent_Identity=30.8510638297872, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI210032110, Length=161, Percent_Identity=31.6770186335404, Blast_Score=81, Evalue=8e-16, Organism=Homo sapiens, GI7657478, Length=200, Percent_Identity=31.5, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI224922801, Length=166, Percent_Identity=34.3373493975904, Blast_Score=79, Evalue=6e-15, Organism=Homo sapiens, GI126723191, Length=196, Percent_Identity=30.1020408163265, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI83715985, Length=251, Percent_Identity=27.8884462151394, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI142976729, Length=192, Percent_Identity=30.2083333333333, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI157739938, Length=199, Percent_Identity=27.1356783919598, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI40807363, Length=224, Percent_Identity=29.4642857142857, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI4503301, Length=226, Percent_Identity=25.2212389380531, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI7706318, Length=203, Percent_Identity=27.0935960591133, Blast_Score=66, Evalue=3e-11, Organism=Escherichia coli, GI1787335, Length=241, Percent_Identity=34.0248962655602, Blast_Score=131, Evalue=4e-32, Organism=Escherichia coli, GI2367175, Length=246, Percent_Identity=35.7723577235772, Blast_Score=122, Evalue=3e-29, Organism=Escherichia coli, GI87082160, Length=242, Percent_Identity=30.9917355371901, Blast_Score=117, Evalue=1e-27, Organism=Escherichia coli, GI1789208, Length=244, Percent_Identity=31.5573770491803, Blast_Score=114, Evalue=8e-27, Organism=Escherichia coli, GI1789378, Length=246, Percent_Identity=32.520325203252, Blast_Score=112, Evalue=2e-26, Organism=Escherichia coli, GI87082100, Length=247, Percent_Identity=35.2226720647773, Blast_Score=112, Evalue=3e-26, Organism=Escherichia coli, GI1787905, Length=238, Percent_Identity=32.3529411764706, Blast_Score=110, Evalue=9e-26, Organism=Escherichia coli, GI1788459, Length=242, Percent_Identity=30.9917355371901, Blast_Score=110, Evalue=1e-25, Organism=Escherichia coli, GI1790717, Length=239, Percent_Identity=27.6150627615063, Blast_Score=102, Evalue=2e-23, Organism=Escherichia coli, GI1786812, Length=256, Percent_Identity=32.421875, Blast_Score=92, Evalue=4e-20, Organism=Escherichia coli, GI1787526, Length=255, Percent_Identity=28.2352941176471, Blast_Score=92, Evalue=4e-20, Organism=Escherichia coli, GI1789057, Length=260, Percent_Identity=26.9230769230769, Blast_Score=72, Evalue=6e-14, Organism=Escherichia coli, GI2367365, Length=240, Percent_Identity=30.4166666666667, Blast_Score=67, Evalue=9e-13, Organism=Escherichia coli, GI1787820, Length=225, Percent_Identity=24, Blast_Score=66, Evalue=3e-12, Organism=Escherichia coli, GI1786701, Length=188, Percent_Identity=28.1914893617021, Blast_Score=62, Evalue=5e-11, Organism=Caenorhabditis elegans, GI17562990, Length=259, Percent_Identity=35.5212355212355, Blast_Score=133, Evalue=1e-31, Organism=Caenorhabditis elegans, GI17563726, Length=252, Percent_Identity=34.9206349206349, Blast_Score=130, Evalue=1e-30, Organism=Caenorhabditis elegans, GI17560150, Length=254, Percent_Identity=33.4645669291339, Blast_Score=129, Evalue=2e-30, Organism=Caenorhabditis elegans, GI17551412, Length=260, Percent_Identity=32.6923076923077, Blast_Score=128, Evalue=3e-30, Organism=Caenorhabditis elegans, GI17562906, Length=265, Percent_Identity=35.0943396226415, Blast_Score=126, Evalue=1e-29, Organism=Caenorhabditis elegans, GI72000259, Length=252, Percent_Identity=33.3333333333333, Blast_Score=125, Evalue=2e-29, Organism=Caenorhabditis elegans, GI17538480, Length=262, Percent_Identity=33.587786259542, Blast_Score=125, Evalue=2e-29, Organism=Caenorhabditis elegans, GI71994604, Length=250, Percent_Identity=34.4, Blast_Score=123, Evalue=1e-28, Organism=Caenorhabditis elegans, GI17560676, Length=250, Percent_Identity=32, Blast_Score=121, Evalue=3e-28, Organism=Caenorhabditis elegans, GI17562908, Length=263, Percent_Identity=34.6007604562738, Blast_Score=121, Evalue=4e-28, Organism=Caenorhabditis elegans, GI25147288, Length=247, Percent_Identity=34.412955465587, Blast_Score=121, Evalue=5e-28, Organism=Caenorhabditis elegans, GI17559104, Length=263, Percent_Identity=31.9391634980989, Blast_Score=120, Evalue=6e-28, Organism=Caenorhabditis elegans, GI17531453, Length=263, Percent_Identity=33.4600760456274, Blast_Score=120, Evalue=9e-28, Organism=Caenorhabditis elegans, GI17562904, Length=266, Percent_Identity=32.3308270676692, Blast_Score=119, Evalue=1e-27, Organism=Caenorhabditis elegans, GI17544670, Length=267, Percent_Identity=34.0823970037453, Blast_Score=119, Evalue=2e-27, Organism=Caenorhabditis elegans, GI17555706, Length=256, Percent_Identity=33.59375, Blast_Score=119, Evalue=2e-27, Organism=Caenorhabditis elegans, GI17560220, Length=263, Percent_Identity=32.6996197718631, Blast_Score=119, Evalue=2e-27, Organism=Caenorhabditis elegans, GI71994600, Length=252, Percent_Identity=36.1111111111111, Blast_Score=119, Evalue=2e-27, Organism=Caenorhabditis elegans, GI17562910, Length=263, Percent_Identity=32.319391634981, Blast_Score=116, Evalue=1e-26, Organism=Caenorhabditis elegans, GI193204405, Length=263, Percent_Identity=31.9391634980989, Blast_Score=116, Evalue=2e-26, Organism=Caenorhabditis elegans, GI17560332, Length=261, Percent_Identity=31.8007662835249, Blast_Score=115, Evalue=3e-26, Organism=Caenorhabditis elegans, GI17561402, Length=247, Percent_Identity=31.1740890688259, Blast_Score=114, Evalue=7e-26, Organism=Caenorhabditis elegans, GI17538486, Length=263, Percent_Identity=30.0380228136882, Blast_Score=110, Evalue=7e-25, Organism=Caenorhabditis elegans, GI17565030, Length=264, Percent_Identity=29.9242424242424, Blast_Score=103, Evalue=8e-23, Organism=Caenorhabditis elegans, GI115534694, Length=241, Percent_Identity=31.5352697095436, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI193203117, Length=263, Percent_Identity=29.277566539924, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI193203115, Length=264, Percent_Identity=29.5454545454545, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17536651, Length=251, Percent_Identity=29.0836653386454, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17536025, Length=281, Percent_Identity=28.4697508896797, Blast_Score=84, Evalue=8e-17, Organism=Caenorhabditis elegans, GI17561272, Length=239, Percent_Identity=28.4518828451883, Blast_Score=82, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17538182, Length=253, Percent_Identity=28.8537549407115, Blast_Score=81, Evalue=7e-16, Organism=Caenorhabditis elegans, GI17508895, Length=202, Percent_Identity=28.7128712871287, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17508651, Length=244, Percent_Identity=25.8196721311475, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17564282, Length=195, Percent_Identity=28.7179487179487, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17568967, Length=192, Percent_Identity=27.6041666666667, Blast_Score=71, Evalue=6e-13, Organism=Saccharomyces cerevisiae, GI6322861, Length=188, Percent_Identity=29.7872340425532, Blast_Score=87, Evalue=3e-18, Organism=Saccharomyces cerevisiae, GI6324126, Length=261, Percent_Identity=26.8199233716475, Blast_Score=84, Evalue=3e-17, Organism=Saccharomyces cerevisiae, GI6323882, Length=250, Percent_Identity=29.2, Blast_Score=82, Evalue=1e-16, Organism=Drosophila melanogaster, GI21355319, Length=247, Percent_Identity=33.6032388663968, Blast_Score=127, Evalue=7e-30, Organism=Drosophila melanogaster, GI24639444, Length=249, Percent_Identity=35.3413654618474, Blast_Score=127, Evalue=1e-29, Organism=Drosophila melanogaster, GI23397609, Length=250, Percent_Identity=35.2, Blast_Score=125, Evalue=2e-29, Organism=Drosophila melanogaster, GI24644339, Length=257, Percent_Identity=34.6303501945525, Blast_Score=120, Evalue=8e-28, Organism=Drosophila melanogaster, GI21357041, Length=253, Percent_Identity=35.5731225296443, Blast_Score=114, Evalue=7e-26, Organism=Drosophila melanogaster, GI28571526, Length=257, Percent_Identity=34.6303501945525, Blast_Score=109, Evalue=2e-24, Organism=Drosophila melanogaster, GI24644337, Length=252, Percent_Identity=36.9047619047619, Blast_Score=106, Evalue=2e-23, Organism=Drosophila melanogaster, GI17737361, Length=255, Percent_Identity=28.2352941176471, Blast_Score=96, Evalue=2e-20, Organism=Drosophila melanogaster, GI18859837, Length=188, Percent_Identity=31.9148936170213, Blast_Score=87, Evalue=8e-18, Organism=Drosophila melanogaster, GI24643142, Length=248, Percent_Identity=29.4354838709677, Blast_Score=82, Evalue=4e-16, Organism=Drosophila melanogaster, GI24640492, Length=210, Percent_Identity=26.6666666666667, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI281364892, Length=196, Percent_Identity=28.0612244897959, Blast_Score=76, Evalue=3e-14, Organism=Drosophila melanogaster, GI21358495, Length=230, Percent_Identity=26.5217391304348, Blast_Score=75, Evalue=4e-14, Organism=Drosophila melanogaster, GI24580925, Length=199, Percent_Identity=31.1557788944724, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI24648944, Length=235, Percent_Identity=25.9574468085106, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI161076933, Length=190, Percent_Identity=26.8421052631579, Blast_Score=65, Evalue=6e-11, Organism=Drosophila melanogaster, GI24584748, Length=190, Percent_Identity=26.8421052631579, Blast_Score=65, Evalue=7e-11, Organism=Drosophila melanogaster, GI24663911, Length=238, Percent_Identity=26.4705882352941, Blast_Score=64, Evalue=1e-10,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 28302; Mature: 28170
Theoretical pI: Translated: 7.05; Mature: 7.05
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.1 %Cys (Translated Protein) 3.3 %Met (Translated Protein) 4.4 %Cys+Met (Translated Protein) 1.1 %Cys (Mature Protein) 2.9 %Met (Mature Protein) 4.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MPSRSDRPIFPKGSRTVSPDLSKETLMSHPVVLITGATAGIGRATALAFAAKGARLVCSG CCCCCCCCCCCCCCCCCCCCCCHHHHHHCCEEEEECCCCCCCHHHHHHHHHCCCEEEECC RNAAAGDALISELREMGAEADFLAADVSREDDVMRLVSHAVERFGCLDIAVNSAGTEGTP CCCCHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCC GSIVEQTVQSYATTFDANVLGTFLCMKHELKAMIGQQRGVVVNLSSTMGSRGNPRNPMYV HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHCCCCCCCCCCCEE ASKHAIEGLTKSAALDVIQANVRVNAVAPGPIETAMLGRIAGGADRLASVAATIPAGRVG EHHHHHHHHHHHHHHHHEEECEEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCC TPEEVADAILFLASDQSTYITGQILHVNGGKTAG CHHHHHHHHEEEECCCCEEEEEEEEEECCCCCCC >Mature Secondary Structure PSRSDRPIFPKGSRTVSPDLSKETLMSHPVVLITGATAGIGRATALAFAAKGARLVCSG CCCCCCCCCCCCCCCCCCCCCHHHHHHCCEEEEECCCCCCCHHHHHHHHHCCCEEEECC RNAAAGDALISELREMGAEADFLAADVSREDDVMRLVSHAVERFGCLDIAVNSAGTEGTP CCCCHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCC GSIVEQTVQSYATTFDANVLGTFLCMKHELKAMIGQQRGVVVNLSSTMGSRGNPRNPMYV HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHCCCCCCCCCCCEE ASKHAIEGLTKSAALDVIQANVRVNAVAPGPIETAMLGRIAGGADRLASVAATIPAGRVG EHHHHHHHHHHHHHHHHEEECEEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCC TPEEVADAILFLASDQSTYITGQILHVNGGKTAG CHHHHHHHHEEEECCCCEEEEEEEEEECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 10360571 [H]