BacMap

Definition	Cupriavidus metallidurans CH34 megaplasmid, complete sequence.
Accession	NC_007974
Length	2,580,084

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The map label for this gene is fabG [H]

Identifier: 94314208

GI number: 94314208

Start: 1990659

End: 1991417

Strand: Direct

Name: fabG [H]

Synonym: Rmet_5289

Alternate gene names: 94314208

Gene position: 1990659-1991417 (Clockwise)

Preceding gene: 94314207

Following gene: 94314211

Centisome position: 77.15

GC content: 63.64

Gene sequence:

>759_bases
ATGGATCTTGGTCTGAAGGACAAACGAGCGATAGTCACCGGCGGCAGCCGGGGTATCGGCAAGGCGATTGCGCTCCAGCT
CGCGCAAGAAGGCGTCGACGTGGTGGTGGCAGCCCGTGGACGCGCGGCGTTGGAAGCGACGGCTGCGGAGCTGGCGACGC
TGACAGGAAGACGGATCGTGCCACTCGCCGTCGACACTTCCAGCAAGGCTTCCGTGGACAGCATGGTGAACCAGGCCATC
GCCGCATTGGGCGGCATCGATATACTGGTCAACGCCGCTGCATTGCCCGGTGGAATCTCATCGGCGTCCCGGCTCGATGA
AATCGACGATGCGCAAGCCATTGAAGACATCGACATCAAGGTGATTGGCTATCTGCGCACCGCGCGGGCGCTCGCGCCAC
ACCTGATTGCCAATGGCTGGGGACGGATCGTGAACATTGGTGGCTTGGCGATCTATCGCACCGGCCGCCCCATTGCCACG
CTGCGCAACGTCGGCGTGGCTGCGATCACCAAGAATCTGGCGGATGAACTCGGGCCGAAGGGCATCAATGTCACGGCGGT
CCATCCCGGAGCGACACGGACGGAGACAACCGACGCGGCATTCGAGGCCTGGGCCGCGGCAAGGACCTCGCTGGGCCGCA
TTGTGGAAGCCCGCGAGGTTGCAGCCGTCGTGGCATTCCTTGCATCGCCAGTGAGTGTGGCGATCAATGGCGATGCCATT
TCTGTCGCTGGCGGGAGCCCCGGCACCATCAGGTACTGA

Upstream 100 bases:

>100_bases
TTCTGAGCGTTCGGCCGGAAGCGCCTTGATGCGACTTGAGGCGACTCGAGGCGACTTCCGGCTTCACTGACGTTGTCCGC
ATACTGCGGGAGAGCGAACC

Downstream 100 bases:

>100_bases
TCGCTCCTGATCGCTGCAGCGCGCGCCGCAGCCCCGACATTCCCGGGGCCCTTGACCGCGCCCCCGGGACACCGCCGACT
TACCCGGCGGTCTTCCCACC

Product: 3-oxoacyl-(acyl-carrier-protein) reductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MDLGLKDKRAIVTGGSRGIGKAIALQLAQEGVDVVVAARGRAALEATAAELATLTGRRIVPLAVDTSSKASVDSMVNQAI
AALGGIDILVNAAALPGGISSASRLDEIDDAQAIEDIDIKVIGYLRTARALAPHLIANGWGRIVNIGGLAIYRTGRPIAT
LRNVGVAAITKNLADELGPKGINVTAVHPGATRTETTDAAFEAWAAARTSLGRIVEAREVAAVVAFLASPVSVAINGDAI
SVAGGSPGTIRY

Sequences:

>Translated_252_residues
MDLGLKDKRAIVTGGSRGIGKAIALQLAQEGVDVVVAARGRAALEATAAELATLTGRRIVPLAVDTSSKASVDSMVNQAI
AALGGIDILVNAAALPGGISSASRLDEIDDAQAIEDIDIKVIGYLRTARALAPHLIANGWGRIVNIGGLAIYRTGRPIAT
LRNVGVAAITKNLADELGPKGINVTAVHPGATRTETTDAAFEAWAAARTSLGRIVEAREVAAVVAFLASPVSVAINGDAI
SVAGGSPGTIRY
>Mature_252_residues
MDLGLKDKRAIVTGGSRGIGKAIALQLAQEGVDVVVAARGRAALEATAAELATLTGRRIVPLAVDTSSKASVDSMVNQAI
AALGGIDILVNAAALPGGISSASRLDEIDDAQAIEDIDIKVIGYLRTARALAPHLIANGWGRIVNIGGLAIYRTGRPIAT
LRNVGVAAITKNLADELGPKGINVTAVHPGATRTETTDAAFEAWAAARTSLGRIVEAREVAAVVAFLASPVSVAINGDAI
SVAGGSPGTIRY

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI19923817, Length=255, Percent_Identity=30.5882352941176, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI10190704, Length=266, Percent_Identity=31.203007518797, Blast_Score=95, Evalue=5e-20,
Organism=Homo sapiens, GI40254992, Length=242, Percent_Identity=30.5785123966942, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI32483357, Length=252, Percent_Identity=30.952380952381, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI5031737, Length=253, Percent_Identity=30.4347826086957, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI7705925, Length=253, Percent_Identity=28.0632411067194, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI4557649, Length=195, Percent_Identity=27.1794871794872, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI15277342, Length=253, Percent_Identity=28.4584980237154, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI40254986, Length=144, Percent_Identity=33.3333333333333, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1789208, Length=256, Percent_Identity=32.8125, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1787335, Length=248, Percent_Identity=31.8548387096774, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1787905, Length=258, Percent_Identity=28.2945736434109, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI87082100, Length=263, Percent_Identity=31.5589353612167, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI87082160, Length=253, Percent_Identity=28.0632411067194, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1790717, Length=256, Percent_Identity=26.953125, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1789378, Length=252, Percent_Identity=26.984126984127, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI2367175, Length=254, Percent_Identity=29.1338582677165, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1787820, Length=196, Percent_Identity=27.5510204081633, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71994604, Length=256, Percent_Identity=33.203125, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17562910, Length=268, Percent_Identity=30.5970149253731, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17559104, Length=266, Percent_Identity=30.8270676691729, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI71994600, Length=253, Percent_Identity=30.8300395256917, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17536651, Length=263, Percent_Identity=30.7984790874525, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17560676, Length=249, Percent_Identity=28.1124497991968, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17562904, Length=262, Percent_Identity=25.9541984732824, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17536025, Length=259, Percent_Identity=32.8185328185328, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17560332, Length=245, Percent_Identity=30.2040816326531, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI25147288, Length=243, Percent_Identity=31.6872427983539, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17555706, Length=247, Percent_Identity=31.1740890688259, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17544670, Length=265, Percent_Identity=27.5471698113208, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71982365, Length=191, Percent_Identity=30.8900523560209, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17560150, Length=257, Percent_Identity=26.4591439688716, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17561402, Length=252, Percent_Identity=27.3809523809524, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI115534694, Length=252, Percent_Identity=28.968253968254, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17560220, Length=260, Percent_Identity=28.4615384615385, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=264, Percent_Identity=28.4090909090909, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=219, Percent_Identity=30.1369863013699, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17538480, Length=241, Percent_Identity=26.5560165975104, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=265, Percent_Identity=29.0566037735849, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI193204405, Length=262, Percent_Identity=28.6259541984733, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17531453, Length=266, Percent_Identity=27.4436090225564, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17562908, Length=263, Percent_Identity=28.5171102661597, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=205, Percent_Identity=26.8292682926829, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI28571526, Length=254, Percent_Identity=34.251968503937, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI23397609, Length=259, Percent_Identity=32.046332046332, Blast_Score=88, Evalue=5e-18,
Organism=Drosophila melanogaster, GI21357041, Length=255, Percent_Identity=32.5490196078431, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21355319, Length=250, Percent_Identity=31.6, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24639444, Length=254, Percent_Identity=31.1023622047244, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24643142, Length=248, Percent_Identity=29.0322580645161, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24644339, Length=256, Percent_Identity=27.734375, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21357673, Length=204, Percent_Identity=31.8627450980392, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21358495, Length=224, Percent_Identity=29.0178571428571, Blast_Score=67, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 25599; Mature: 25599

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLGLKDKRAIVTGGSRGIGKAIALQLAQEGVDVVVAARGRAALEATAAELATLTGRRIV
CCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHCCCEEE
PLAVDTSSKASVDSMVNQAIAALGGIDILVNAAALPGGISSASRLDEIDDAQAIEDIDIK
EEEECCCCCHHHHHHHHHHHHHHCCHHHEEEHHCCCCCCCCHHHHHHHHHHHHHHHCCEE
VIGYLRTARALAPHLIANGWGRIVNIGGLAIYRTGRPIATLRNVGVAAITKNLADELGPK
EEHHHHHHHHHHHHHHHCCCCCEEEECCEEEEECCCCHHHHHHCCHHHHHHHHHHHHCCC
GINVTAVHPGATRTETTDAAFEAWAAARTSLGRIVEAREVAAVVAFLASPVSVAINGDAI
CCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCEE
SVAGGSPGTIRY
EECCCCCCCCCC
>Mature Secondary Structure
MDLGLKDKRAIVTGGSRGIGKAIALQLAQEGVDVVVAARGRAALEATAAELATLTGRRIV
CCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHCCCEEE
PLAVDTSSKASVDSMVNQAIAALGGIDILVNAAALPGGISSASRLDEIDDAQAIEDIDIK
EEEECCCCCHHHHHHHHHHHHHHCCHHHEEEHHCCCCCCCCHHHHHHHHHHHHHHHCCEE
VIGYLRTARALAPHLIANGWGRIVNIGGLAIYRTGRPIATLRNVGVAAITKNLADELGPK
EEHHHHHHHHHHHHHHHCCCCCEEEECCEEEEECCCCHHHHHHCCHHHHHHHHHHHHCCC
GINVTAVHPGATRTETTDAAFEAWAAARTSLGRIVEAREVAAVVAFLASPVSVAINGDAI
CCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCEE
SVAGGSPGTIRY
EECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9384377; 9534248; 8654983 [H]