Click here to switch to the map view.

The map label for this gene is acoR [H]

Identifier: 94314046

GI number: 94314046

Start: 1822505

End: 1824469

Strand: Direct

Name: acoR [H]

Synonym: Rmet_5127

Alternate gene names: 94314046

Gene position: 1822505-1824469 (Clockwise)

Preceding gene: 94314044

Following gene: 94314054

Centisome position: 70.64

GC content: 65.34

Gene sequence:

>1965_bases
ATGATTTCCCACGTGGCCGCCGCCGGGCGCGCTTCGCGAGGCGGCACGTCCAGTGAGGCCCCGGAGACCGATCAGCCCGG
ACTGATCGCCCAAGCGCACGAGCGTTCGAAATCGTATGGCCTGCGGCCCCATGAATCGCCCGAGTTCCTCCCCGCGCGGC
CAAGCGAGCTGAAGACGCAGATCGAGCGCAGCCAGTCGCTGTTCACCCACGCGCTGCCTGTCATGGAGACGCTCCACAAC
CAGATCGTCAACACGCAAAGCATGGTGATCCTGACCGACTCGGCTGGATTGATCCTGCATTCGCTTGGCGATGATGACTT
TCTGGCCAAGGCCAGCAAGGTGGCCTTGCAGCCGGGCGCGCTGTGGTCCGAGGAAAGCCGGGGCACCAACGCCATCGGCA
CGGCACTGGTCGAGGGTCGGCCGACACTGGTCCACGGTGCCGAGCACTACCTGGAAGCCAACCGGTTCCTCACCTGCTCG
TGCGCGCCGATCCTCGACCCGTACGGCAGGACCGTCGGCGCGCTCGACGTCACCGGCGATCAGCGCGGCTTCCACAAGCA
CACCATGGCCCTGGTGCGCATGTCGGCGCAGATGATCGAGAACCAGTTGTTCGCCAATGCCTTCCAGGACGTGGTGTGCG
TGCACTTCCACTCGCGGCCGGAGTTCATCGGCACGCTGGTCGAAGGCATCGCCGCTTTCACGCCTGCCGGGCGCTTTCTC
TCCGCCAACCGGAGCGGCGTCTTCCAGCTGGAATTGTCGATCGGGGCCTTGCAGGCGCATACCTTCTCATCGCTGTTCGG
CATGTCGATGCCCCAGCTGATCGACTCGGAACGCGGCGCGCCCGCCGGCACCGTCCAATTGCAACTGCCGAGTGGCGTGA
AGGTGTATGCGCGCGTGGAGTGGAAACGGCCCGCCAGCCAGATCGCGCGCGCCACCATAAGCGGCGACGCGGCCCACCAG
CGCGATACGAAGCCAGCACGCCGACAGGGCGACGGGACGCTGCAGCCAGACGGTCTGGATGCCCTCGATACTGGCGACAC
CCAGATCAAGAGCGTCATCGGCAAGCTGCGCAAGGTCATCGGCAAGGACATTCCGATTATGGTGCTGGGCGAGACCGGTA
CCGGCAAGGAGTTGCTGGCCCGTGCCATCCATGCCGACAGCCCACGCCGCGCCGGGCCATTCGTCGCCGTCAATTGCGCT
TCGATTCCCGAGGCATTGATCGAGTCCGAGCTGTTTGGCTACGAAGAGGGGGCATTCACGGGCGCGCGAAAAAAGGGCGG
CATCGGCAAAATGGTGCTGGCCAACGGCGGCACGCTGTTCCTCGACGAGATCGGCGATATGCCACTGCATCTGCAGGCGC
GGCTGCTGCGCGCGCTACAGGAGCGTACGGTGTCGCCGCTGGGCAGCAACAAGCTGGTCCAGGTCGACGTCGCCGTGGTT
TGCGCCACGCACCGTAACATGCGCGAGATGATGGCCAGCGGCCAGTTCCGCGAGGACCTCTATTACCGCCTGAATGGATT
CGTGGTGCGTCTGCCGGCGTTGCGCGAGCGTGACGACCTGGATGCCGTGGCGCATAGGCTGCTGCAACAGGACCATGCGA
ATGCGCTGCCGCTCAGCGAACCAGTGGCACGGATGCTGCGCAGCTATCACTGGCCCGGCAATATCCGCCAGCTCGCCAAC
CTGCTACGCACCGCGCAACTGATGGCCGAGGGATCACCGGAAATCACCGAAGACCACCTGCCTGACGACTTCCTCGAAGA
CTGGCGCGCGCGACACGCGGCGGAGCCGAACGGAGACGATACCCGCCCCAGTCGGCTCGCCGACATCGAAAGCATGGCCA
TCCTGACTGCGCTGAAGGCACACGACGGCAATATCTCGGCGACGGCCAAGGCGCTCGGCGTTTCACGCAATACCGTCTAC
CGCAGGATCGAGGAAGCGGGCGGCCCATCGCCGCAGGGCGACTGA

Upstream 100 bases:

>100_bases
TGTGCGTGTCCACGGCCTGCGGCGTCACTTCGCCCGCACGGTTGCGGGCGATCCCCCGGCCAGACGCGCACGGACACGGG
GCGACTTAAAGGAGACATTC

Downstream 100 bases:

>100_bases
CCACCCTTCACGATGGCGGGAGCGGAAGCAACCGCCCCCGTCAACGATCAGCAGCAGTTCAGAAGAAGCCCAGCGGTTGC
GTGTCGTAGCTGACCAGCAG

Product: putative sigma-54-dependent transcriptional regulator, HTH Fis-type family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 654; Mature: 654

Protein sequence:

>654_residues
MISHVAAAGRASRGGTSSEAPETDQPGLIAQAHERSKSYGLRPHESPEFLPARPSELKTQIERSQSLFTHALPVMETLHN
QIVNTQSMVILTDSAGLILHSLGDDDFLAKASKVALQPGALWSEESRGTNAIGTALVEGRPTLVHGAEHYLEANRFLTCS
CAPILDPYGRTVGALDVTGDQRGFHKHTMALVRMSAQMIENQLFANAFQDVVCVHFHSRPEFIGTLVEGIAAFTPAGRFL
SANRSGVFQLELSIGALQAHTFSSLFGMSMPQLIDSERGAPAGTVQLQLPSGVKVYARVEWKRPASQIARATISGDAAHQ
RDTKPARRQGDGTLQPDGLDALDTGDTQIKSVIGKLRKVIGKDIPIMVLGETGTGKELLARAIHADSPRRAGPFVAVNCA
SIPEALIESELFGYEEGAFTGARKKGGIGKMVLANGGTLFLDEIGDMPLHLQARLLRALQERTVSPLGSNKLVQVDVAVV
CATHRNMREMMASGQFREDLYYRLNGFVVRLPALRERDDLDAVAHRLLQQDHANALPLSEPVARMLRSYHWPGNIRQLAN
LLRTAQLMAEGSPEITEDHLPDDFLEDWRARHAAEPNGDDTRPSRLADIESMAILTALKAHDGNISATAKALGVSRNTVY
RRIEEAGGPSPQGD

Sequences:

>Translated_654_residues
MISHVAAAGRASRGGTSSEAPETDQPGLIAQAHERSKSYGLRPHESPEFLPARPSELKTQIERSQSLFTHALPVMETLHN
QIVNTQSMVILTDSAGLILHSLGDDDFLAKASKVALQPGALWSEESRGTNAIGTALVEGRPTLVHGAEHYLEANRFLTCS
CAPILDPYGRTVGALDVTGDQRGFHKHTMALVRMSAQMIENQLFANAFQDVVCVHFHSRPEFIGTLVEGIAAFTPAGRFL
SANRSGVFQLELSIGALQAHTFSSLFGMSMPQLIDSERGAPAGTVQLQLPSGVKVYARVEWKRPASQIARATISGDAAHQ
RDTKPARRQGDGTLQPDGLDALDTGDTQIKSVIGKLRKVIGKDIPIMVLGETGTGKELLARAIHADSPRRAGPFVAVNCA
SIPEALIESELFGYEEGAFTGARKKGGIGKMVLANGGTLFLDEIGDMPLHLQARLLRALQERTVSPLGSNKLVQVDVAVV
CATHRNMREMMASGQFREDLYYRLNGFVVRLPALRERDDLDAVAHRLLQQDHANALPLSEPVARMLRSYHWPGNIRQLAN
LLRTAQLMAEGSPEITEDHLPDDFLEDWRARHAAEPNGDDTRPSRLADIESMAILTALKAHDGNISATAKALGVSRNTVY
RRIEEAGGPSPQGD
>Mature_654_residues
MISHVAAAGRASRGGTSSEAPETDQPGLIAQAHERSKSYGLRPHESPEFLPARPSELKTQIERSQSLFTHALPVMETLHN
QIVNTQSMVILTDSAGLILHSLGDDDFLAKASKVALQPGALWSEESRGTNAIGTALVEGRPTLVHGAEHYLEANRFLTCS
CAPILDPYGRTVGALDVTGDQRGFHKHTMALVRMSAQMIENQLFANAFQDVVCVHFHSRPEFIGTLVEGIAAFTPAGRFL
SANRSGVFQLELSIGALQAHTFSSLFGMSMPQLIDSERGAPAGTVQLQLPSGVKVYARVEWKRPASQIARATISGDAAHQ
RDTKPARRQGDGTLQPDGLDALDTGDTQIKSVIGKLRKVIGKDIPIMVLGETGTGKELLARAIHADSPRRAGPFVAVNCA
SIPEALIESELFGYEEGAFTGARKKGGIGKMVLANGGTLFLDEIGDMPLHLQARLLRALQERTVSPLGSNKLVQVDVAVV
CATHRNMREMMASGQFREDLYYRLNGFVVRLPALRERDDLDAVAHRLLQQDHANALPLSEPVARMLRSYHWPGNIRQLAN
LLRTAQLMAEGSPEITEDHLPDDFLEDWRARHAAEPNGDDTRPSRLADIESMAILTALKAHDGNISATAKALGVSRNTVY
RRIEEAGGPSPQGD

Specific function: Required for sigma-54-dependent transcription of acoXABC [H]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1789233, Length=311, Percent_Identity=42.1221864951768, Blast_Score=237, Evalue=2e-63,
Organism=Escherichia coli, GI1788550, Length=293, Percent_Identity=41.296928327645, Blast_Score=222, Evalue=7e-59,
Organism=Escherichia coli, GI1788905, Length=295, Percent_Identity=41.6949152542373, Blast_Score=217, Evalue=2e-57,
Organism=Escherichia coli, GI1790437, Length=287, Percent_Identity=43.205574912892, Blast_Score=215, Evalue=9e-57,
Organism=Escherichia coli, GI87082117, Length=371, Percent_Identity=37.466307277628, Blast_Score=213, Evalue=3e-56,
Organism=Escherichia coli, GI1786524, Length=301, Percent_Identity=43.1893687707641, Blast_Score=209, Evalue=4e-55,
Organism=Escherichia coli, GI1789087, Length=308, Percent_Identity=40.5844155844156, Blast_Score=209, Evalue=6e-55,
Organism=Escherichia coli, GI1790299, Length=320, Percent_Identity=40.3125, Blast_Score=207, Evalue=2e-54,
Organism=Escherichia coli, GI87082152, Length=236, Percent_Identity=42.7966101694915, Blast_Score=183, Evalue=3e-47,
Organism=Escherichia coli, GI1787583, Length=309, Percent_Identity=37.8640776699029, Blast_Score=178, Evalue=1e-45,
Organism=Escherichia coli, GI87081872, Length=206, Percent_Identity=44.1747572815534, Blast_Score=166, Evalue=5e-42,
Organism=Escherichia coli, GI87081858, Length=639, Percent_Identity=22.5352112676056, Blast_Score=153, Evalue=4e-38,
Organism=Escherichia coli, GI1789828, Length=290, Percent_Identity=36.2068965517241, Blast_Score=139, Evalue=4e-34,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 70909; Mature: 70909

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISHVAAAGRASRGGTSSEAPETDQPGLIAQAHERSKSYGLRPHESPEFLPARPSELKTQ
CCCCHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHH
IERSQSLFTHALPVMETLHNQIVNTQSMVILTDSAGLILHSLGDDDFLAKASKVALQPGA
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEECCCCHHHHHHHHHEECCCC
LWSEESRGTNAIGTALVEGRPTLVHGAEHYLEANRFLTCSCAPILDPYGRTVGALDVTGD
CCCCCCCCCCHHHHHHCCCCCCEECCHHHHHHCCCEEEEECCHHCCCCCCCEEEEEECCC
QRGFHKHTMALVRMSAQMIENQLFANAFQDVVCVHFHSRPEFIGTLVEGIAAFTPAGRFL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHCCCCCEE
SANRSGVFQLELSIGALQAHTFSSLFGMSMPQLIDSERGAPAGTVQLQLPSGVKVYARVE
ECCCCCEEEEEEECCHHHHHHHHHHHHCCCHHHHHCCCCCCCCEEEEECCCCCEEEEEEE
WKRPASQIARATISGDAAHQRDTKPARRQGDGTLQPDGLDALDTGDTQIKSVIGKLRKVI
CCCCHHHHHHHHCCCCCHHCCCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
GKDIPIMVLGETGTGKELLARAIHADSPRRAGPFVAVNCASIPEALIESELFGYEEGAFT
CCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCC
GARKKGGIGKMVLANGGTLFLDEIGDMPLHLQARLLRALQERTVSPLGSNKLVQVDVAVV
CCCCCCCCCEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEE
CATHRNMREMMASGQFREDLYYRLNGFVVRLPALRERDDLDAVAHRLLQQDHANALPLSE
EHHHHHHHHHHHCCCHHHHHHHHHCCEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCHH
PVARMLRSYHWPGNIRQLANLLRTAQLMAEGSPEITEDHLPDDFLEDWRARHAAEPNGDD
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCC
TRPSRLADIESMAILTALKAHDGNISATAKALGVSRNTVYRRIEEAGGPSPQGD
CCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MISHVAAAGRASRGGTSSEAPETDQPGLIAQAHERSKSYGLRPHESPEFLPARPSELKTQ
CCCCHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHH
IERSQSLFTHALPVMETLHNQIVNTQSMVILTDSAGLILHSLGDDDFLAKASKVALQPGA
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEECCCCHHHHHHHHHEECCCC
LWSEESRGTNAIGTALVEGRPTLVHGAEHYLEANRFLTCSCAPILDPYGRTVGALDVTGD
CCCCCCCCCCHHHHHHCCCCCCEECCHHHHHHCCCEEEEECCHHCCCCCCCEEEEEECCC
QRGFHKHTMALVRMSAQMIENQLFANAFQDVVCVHFHSRPEFIGTLVEGIAAFTPAGRFL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHCCCCCEE
SANRSGVFQLELSIGALQAHTFSSLFGMSMPQLIDSERGAPAGTVQLQLPSGVKVYARVE
ECCCCCEEEEEEECCHHHHHHHHHHHHCCCHHHHHCCCCCCCCEEEEECCCCCEEEEEEE
WKRPASQIARATISGDAAHQRDTKPARRQGDGTLQPDGLDALDTGDTQIKSVIGKLRKVI
CCCCHHHHHHHHCCCCCHHCCCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
GKDIPIMVLGETGTGKELLARAIHADSPRRAGPFVAVNCASIPEALIESELFGYEEGAFT
CCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCC
GARKKGGIGKMVLANGGTLFLDEIGDMPLHLQARLLRALQERTVSPLGSNKLVQVDVAVV
CCCCCCCCCEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEE
CATHRNMREMMASGQFREDLYYRLNGFVVRLPALRERDDLDAVAHRLLQQDHANALPLSE
EHHHHHHHHHHHCCCHHHHHHHHHCCEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCHH
PVARMLRSYHWPGNIRQLANLLRTAQLMAEGSPEITEDHLPDDFLEDWRARHAAEPNGDD
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCC
TRPSRLADIESMAILTALKAHDGNISATAKALGVSRNTVYRRIEEAGGPSPQGD
CCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1378052 [H]