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The map label for this gene is paaG [C]

Identifier: 94314013

GI number: 94314013

Start: 1784889

End: 1785758

Strand: Direct

Name: paaG [C]

Synonym: Rmet_5094

Alternate gene names: 94314013

Gene position: 1784889-1785758 (Clockwise)

Preceding gene: 94314012

Following gene: 94314017

Centisome position: 69.18

GC content: 63.91

Gene sequence:

>870_bases
ATGACCACTACGCCCCCGGCTTTCGAGACGCTTCAGTACGCCGTGCAGAACGGCATTGCCACGATTTCGCTTCACCGCCC
CGAGAAGATGAACGCGTTCACACACCAGATGTGTGAAGACCTGATCGCGGCATTTGACGCGACGGATGCCGACGACAATG
TGCGCGCCGTGATCGTGACCGGCAGCGGCCGTGCGTTCTGCGCGGGTGCCGACCTGTCCAGCGGTGGCGCCACCTTCGAC
TACGAGAAGCGTTATGGATCGACCGGCGTGAAACGTGACGGCGGCGGCCGAGTCGTGCTGCGCATTTTCCGCAGCCTCAA
GCCGGTCATCGCTGCCGTGAACGGCGCCGCGGTTGGTGTCGGCGTCACCATGCAGTTGCCGATGGACATCCGCATCGCCT
CGACCGACGCAAAGTTCGGCCTCGTGTTCGCACGGCGGGGGATTACGCCGGAAGCGGCTTCGTCATGGTTCCTGTCGCGC
GTCGTGGGGATTTCGACGGCACTGGAATGGTGTTTTTCGGGTCGCGTATTCAGCGCGCAGGAAGCGCACGAGCGCGGACT
CGTCCGTTCGCTCCATGCGCCCGAGGATCTGCTGCCGGCGGCCTATGCCATTGCCAGGGAGATCGCGGACAACGCCGCCC
CGGTTTCGGTCGCCATGGCGCGCCAGATGATCTGGCGCATGGCAGGGGCCGCTCATCCCATGGACGCCCACAAGGTGGAT
AGCCGCGCGATCCAGTCGCGTGGTCAGTCGGACGATGCGAAGGAAGGTATTGCGAGCTTTCTCGAGAAGCGTCCGGCACA
GTTCCCGAACCGCGTATCGAGCCAGATGCCGGACTTCTTTGACTGGCAGGGCGAGCCAGACTTCGAGTAA

Upstream 100 bases:

>100_bases
ACGGCTCCGCGGCCCTGGCCTGTTCCGCGCAGCGAAAGCCCCGCACCACGACGGCGCCGCAGGTGCTACGCTGCATCCAC
TTCCCAACAGGCACGCGACC

Downstream 100 bases:

>100_bases
GCCGCCAATCGCCGGCGATTCGCGAGCCGAGGCGGTACGCGAATCGTCGTCATAGGATGGCTCGGCTATCGCAGCTTGAG
CAGATCCTCGTACAGCGCCC

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 289; Mature: 288

Protein sequence:

>289_residues
MTTTPPAFETLQYAVQNGIATISLHRPEKMNAFTHQMCEDLIAAFDATDADDNVRAVIVTGSGRAFCAGADLSSGGATFD
YEKRYGSTGVKRDGGGRVVLRIFRSLKPVIAAVNGAAVGVGVTMQLPMDIRIASTDAKFGLVFARRGITPEAASSWFLSR
VVGISTALEWCFSGRVFSAQEAHERGLVRSLHAPEDLLPAAYAIAREIADNAAPVSVAMARQMIWRMAGAAHPMDAHKVD
SRAIQSRGQSDDAKEGIASFLEKRPAQFPNRVSSQMPDFFDWQGEPDFE

Sequences:

>Translated_289_residues
MTTTPPAFETLQYAVQNGIATISLHRPEKMNAFTHQMCEDLIAAFDATDADDNVRAVIVTGSGRAFCAGADLSSGGATFD
YEKRYGSTGVKRDGGGRVVLRIFRSLKPVIAAVNGAAVGVGVTMQLPMDIRIASTDAKFGLVFARRGITPEAASSWFLSR
VVGISTALEWCFSGRVFSAQEAHERGLVRSLHAPEDLLPAAYAIAREIADNAAPVSVAMARQMIWRMAGAAHPMDAHKVD
SRAIQSRGQSDDAKEGIASFLEKRPAQFPNRVSSQMPDFFDWQGEPDFE
>Mature_288_residues
TTTPPAFETLQYAVQNGIATISLHRPEKMNAFTHQMCEDLIAAFDATDADDNVRAVIVTGSGRAFCAGADLSSGGATFDY
EKRYGSTGVKRDGGGRVVLRIFRSLKPVIAAVNGAAVGVGVTMQLPMDIRIASTDAKFGLVFARRGITPEAASSWFLSRV
VGISTALEWCFSGRVFSAQEAHERGLVRSLHAPEDLLPAAYAIAREIADNAAPVSVAMARQMIWRMAGAAHPMDAHKVDS
RAIQSRGQSDDAKEGIASFLEKRPAQFPNRVSSQMPDFFDWQGEPDFE

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=260, Percent_Identity=33.4615384615385, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI45643119, Length=269, Percent_Identity=27.5092936802974, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI260275230, Length=269, Percent_Identity=27.5092936802974, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI260274832, Length=271, Percent_Identity=28.0442804428044, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI31542718, Length=257, Percent_Identity=31.1284046692607, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI68989263, Length=174, Percent_Identity=31.6091954022989, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI4502327, Length=263, Percent_Identity=29.6577946768061, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI116235487, Length=188, Percent_Identity=29.7872340425532, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI20127408, Length=188, Percent_Identity=27.6595744680851, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI70995211, Length=222, Percent_Identity=30.6306306306306, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI221136756, Length=216, Percent_Identity=26.3888888888889, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI221136753, Length=216, Percent_Identity=26.3888888888889, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI221307494, Length=217, Percent_Identity=27.1889400921659, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI4757966, Length=190, Percent_Identity=25.7894736842105, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI51538581, Length=190, Percent_Identity=25.7894736842105, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI25453481, Length=190, Percent_Identity=25.7894736842105, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI51538573, Length=190, Percent_Identity=25.7894736842105, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI4757968, Length=190, Percent_Identity=25.7894736842105, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI49355787, Length=190, Percent_Identity=25.7894736842105, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1787660, Length=265, Percent_Identity=33.5849056603774, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1787659, Length=258, Percent_Identity=31.7829457364341, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1788597, Length=208, Percent_Identity=30.7692307692308, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI221142681, Length=261, Percent_Identity=29.5019157088123, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87082183, Length=271, Percent_Identity=25.0922509225092, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788682, Length=231, Percent_Identity=27.7056277056277, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1790281, Length=239, Percent_Identity=25.1046025104602, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17554946, Length=275, Percent_Identity=30.1818181818182, Blast_Score=114, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17549921, Length=215, Percent_Identity=35.3488372093023, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI25145438, Length=247, Percent_Identity=29.9595141700405, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17535521, Length=251, Percent_Identity=26.6932270916335, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17560910, Length=256, Percent_Identity=26.953125, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17536985, Length=238, Percent_Identity=26.890756302521, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17540714, Length=228, Percent_Identity=31.5789473684211, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17540306, Length=250, Percent_Identity=25.6, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17534483, Length=212, Percent_Identity=28.7735849056604, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17508953, Length=245, Percent_Identity=26.9387755102041, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17508951, Length=241, Percent_Identity=27.3858921161826, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI25144276, Length=241, Percent_Identity=27.3858921161826, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6320241, Length=204, Percent_Identity=26.9607843137255, Blast_Score=87, Evalue=3e-18,
Organism=Drosophila melanogaster, GI20129971, Length=254, Percent_Identity=31.496062992126, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24653477, Length=254, Percent_Identity=31.496062992126, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24653139, Length=255, Percent_Identity=34.1176470588235, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI19920382, Length=212, Percent_Identity=35.377358490566, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24654903, Length=261, Percent_Identity=22.2222222222222, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21357171, Length=174, Percent_Identity=29.3103448275862, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24650670, Length=193, Percent_Identity=29.5336787564767, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 31214; Mature: 31082

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTPPAFETLQYAVQNGIATISLHRPEKMNAFTHQMCEDLIAAFDATDADDNVRAVIVT
CCCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEE
GSGRAFCAGADLSSGGATFDYEKRYGSTGVKRDGGGRVVLRIFRSLKPVIAAVNGAAVGV
CCCCEEEECCCCCCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEE
GVTMQLPMDIRIASTDAKFGLVFARRGITPEAASSWFLSRVVGISTALEWCFSGRVFSAQ
EEEEECCCEEEEECCCCCCEEEEHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
EAHERGLVRSLHAPEDLLPAAYAIAREIADNAAPVSVAMARQMIWRMAGAAHPMDAHKVD
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHH
SRAIQSRGQSDDAKEGIASFLEKRPAQFPNRVSSQMPDFFDWQGEPDFE
HHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCCHHCCCCCCCCC
>Mature Secondary Structure 
TTTPPAFETLQYAVQNGIATISLHRPEKMNAFTHQMCEDLIAAFDATDADDNVRAVIVT
CCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEE
GSGRAFCAGADLSSGGATFDYEKRYGSTGVKRDGGGRVVLRIFRSLKPVIAAVNGAAVGV
CCCCEEEECCCCCCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEE
GVTMQLPMDIRIASTDAKFGLVFARRGITPEAASSWFLSRVVGISTALEWCFSGRVFSAQ
EEEEECCCEEEEECCCCCCEEEEHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
EAHERGLVRSLHAPEDLLPAAYAIAREIADNAAPVSVAMARQMIWRMAGAAHPMDAHKVD
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHH
SRAIQSRGQSDDAKEGIASFLEKRPAQFPNRVSSQMPDFFDWQGEPDFE
HHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCCHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA