Click here to switch to the map view.

The map label for this gene is prx5 [C]

Identifier: 94313811

GI number: 94313811

Start: 1551520

End: 1552251

Strand: Reverse

Name: prx5 [C]

Synonym: Rmet_4889

Alternate gene names: 94313811

Gene position: 1552251-1551520 (Counterclockwise)

Preceding gene: 94313815

Following gene: 94313810

Centisome position: 60.16

GC content: 61.34

Gene sequence:

>732_bases
ATGCTGCAATCCCGTGAAGGCCAACGCGTTCCCAACGTCACGTTCCGTGTGCGTGCAAACAATGAGTGGAAGGACGTGAC
CACGGCCGAACTGTTCGACGGCAAGACCGTAGTGTTGTTCTCGCTGCCGGGCGCCTTCACCCCGACGTGCTCGTCCACAC
ACCTGCCGCGCTACAACGAACTGGCGCCGGTGTTCGCCAAGCAAGGCGTCGACGCGATCCTGTGCGTGTCGGTCAACGAC
ACCTTTGTCATGAACGAGTGGGCCAAGGACCAGGAGTCCGAGAACATCGTCATGATCCCTGACGGCAACGGCGAATTCAC
CGACGGCATGGGCATGCTCGTCGACAAGGCCGACCTCGGTTTCGGCAAGCGTAGCTGGCGCTATTCGATGTTGGTCAAGG
ACGGTGTGGTGGACAAGATGTTCATCGAGCCGGAAGAGCCGGGCGACCCGTTCAAGGTGTCGGATGCCGACACGATGCTG
AACTACATCGCGCCGACCGCCAAGCAGCCGGACCAGGTGGTGGTGTTCTCGAAGATTGGCTGCTCGCACTGCGCCAAGGC
CAAGCAACTGCTGTCGGACAACGGCTTCGAGTACATCGACGTGCCGCTCGAGAACAAGATTCGCGGCAAGGTGCTGGGCG
CCGTGTCGGGCGAAATGACCGCGCCGCAGGTGTTCATCAACGGCAAGCTGGTCGGTGGCGCAGAAGCGCTCGAACAGTAC
CTGGCTCGCTGA

Upstream 100 bases:

>100_bases
TTGGTTGAAACGATGAATTGTACAAATCACATTGGGATCTTCAGAATCCACTCCATCGCTGCAACACGCGGCGCCAACCT
GACCCAGAGGAGTGATCCAG

Downstream 100 bases:

>100_bases
TCTCCCTCGCCCGGGCCCGGTTCCCCCGACCGGTGTCCTGGGCACCCTCTCCCCCCTAGCAAGTCGTCGTATCCGATGGC
GCCGCGTATGTGGCGGCGCC

Product: peroxiredoxin/glutaredoxin, Thioredoxin reductase

Products: NA

Alternate protein names: Thioredoxin reductase [H]

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MLQSREGQRVPNVTFRVRANNEWKDVTTAELFDGKTVVLFSLPGAFTPTCSSTHLPRYNELAPVFAKQGVDAILCVSVND
TFVMNEWAKDQESENIVMIPDGNGEFTDGMGMLVDKADLGFGKRSWRYSMLVKDGVVDKMFIEPEEPGDPFKVSDADTML
NYIAPTAKQPDQVVVFSKIGCSHCAKAKQLLSDNGFEYIDVPLENKIRGKVLGAVSGEMTAPQVFINGKLVGGAEALEQY
LAR

Sequences:

>Translated_243_residues
MLQSREGQRVPNVTFRVRANNEWKDVTTAELFDGKTVVLFSLPGAFTPTCSSTHLPRYNELAPVFAKQGVDAILCVSVND
TFVMNEWAKDQESENIVMIPDGNGEFTDGMGMLVDKADLGFGKRSWRYSMLVKDGVVDKMFIEPEEPGDPFKVSDADTML
NYIAPTAKQPDQVVVFSKIGCSHCAKAKQLLSDNGFEYIDVPLENKIRGKVLGAVSGEMTAPQVFINGKLVGGAEALEQY
LAR
>Mature_243_residues
MLQSREGQRVPNVTFRVRANNEWKDVTTAELFDGKTVVLFSLPGAFTPTCSSTHLPRYNELAPVFAKQGVDAILCVSVND
TFVMNEWAKDQESENIVMIPDGNGEFTDGMGMLVDKADLGFGKRSWRYSMLVKDGVVDKMFIEPEEPGDPFKVSDADTML
NYIAPTAKQPDQVVVFSKIGCSHCAKAKQLLSDNGFEYIDVPLENKIRGKVLGAVSGEMTAPQVFINGKLVGGAEALEQY
LAR

Specific function: The Disulfide Bond Functions As An Electron Carrier In The Glutathione-Dependent Synthesis Of Deoxyribonucleotides By The Enzyme Ribonucleotide Reductase. In Addition, It Is Also Involved In Reducing Some Disulfides In A Coupled System With Glutathione R

COG id: COG0678

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI6912238, Length=126, Percent_Identity=43.6507936507937, Blast_Score=104, Evalue=6e-23,
Organism=Drosophila melanogaster, GI78706776, Length=125, Percent_Identity=45.6, Blast_Score=108, Evalue=3e-24,
Organism=Drosophila melanogaster, GI78709078, Length=125, Percent_Identity=45.6, Blast_Score=108, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011767
- InterPro:   IPR002109
- InterPro:   IPR011906
- InterPro:   IPR014025
- InterPro:   IPR013740
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin; PF08534 Redoxin [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 26737; Mature: 26737

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQSREGQRVPNVTFRVRANNEWKDVTTAELFDGKTVVLFSLPGAFTPTCSSTHLPRYNE
CCCCCCCCCCCCEEEEEEECCCCCCCEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCC
LAPVFAKQGVDAILCVSVNDTFVMNEWAKDQESENIVMIPDGNGEFTDGMGMLVDKADLG
HHHHHHHCCCCEEEEEECCCEEEECCCCCCCCCCCEEEEECCCCCCCCCCEEEEECCCCC
FGKRSWRYSMLVKDGVVDKMFIEPEEPGDPFKVSDADTMLNYIAPTAKQPDQVVVFSKIG
CCCCCEEEEEEEECCCEEEEEECCCCCCCCEEECCHHHHHHHHCCCCCCCCEEEEEECCC
CSHCAKAKQLLSDNGFEYIDVPLENKIRGKVLGAVSGEMTAPQVFINGKLVGGAEALEQY
HHHHHHHHHHHCCCCCEEEECCCCCCCCCEEEEECCCCCCCCEEEEECEEECCHHHHHHH
LAR
HCC
>Mature Secondary Structure
MLQSREGQRVPNVTFRVRANNEWKDVTTAELFDGKTVVLFSLPGAFTPTCSSTHLPRYNE
CCCCCCCCCCCCEEEEEEECCCCCCCEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCC
LAPVFAKQGVDAILCVSVNDTFVMNEWAKDQESENIVMIPDGNGEFTDGMGMLVDKADLG
HHHHHHHCCCCEEEEEECCCEEEECCCCCCCCCCCEEEEECCCCCCCCCCEEEEECCCCC
FGKRSWRYSMLVKDGVVDKMFIEPEEPGDPFKVSDADTMLNYIAPTAKQPDQVVVFSKIG
CCCCCEEEEEEEECCCEEEEEECCCCCCCCEEECCHHHHHHHHCCCCCCCCEEEEEECCC
CSHCAKAKQLLSDNGFEYIDVPLENKIRGKVLGAVSGEMTAPQVFINGKLVGGAEALEQY
HHHHHHHHHHHCCCCCEEEECCCCCCCCCEEEEECCCCCCCCEEEEECEEECCHHHHHHH
LAR
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]