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The map label for this gene is adh [H]

Identifier: 94313774

GI number: 94313774

Start: 1510099

End: 1511109

Strand: Direct

Name: adh [H]

Synonym: Rmet_4852

Alternate gene names: 94313774

Gene position: 1510099-1511109 (Clockwise)

Preceding gene: 94313773

Following gene: 94313775

Centisome position: 58.53

GC content: 68.25

Gene sequence:

>1011_bases
ATGAAGGCGCTCGTATGCAAGCAGTTCGGCGGCGTCGAGGATGTGGAACTCGCGACCGTGTCCGAACCCGCCCTGGCCGA
CCCCCATGCGGTCACGATCGAAGTGGAGTTCGCCAGCGTCAGCCATGCCACCGGCCTGATGATCGCTGGCCAGTATCAGC
GCCGCCCGCCGCTGCCATTCGTGCCCGGCACGGAAGCGGTGGGACGCGTGGTGGCCTGCGGCAAGGCCGTCACACGGCTG
CGCCCAGGTGACCGGGTCGTAGCCATTGCCGACTGGGGCTGCTACGCGGAGCGATTCACGGTACCTGAGTACACCGTCTA
CCCTGTCCCCGACTCGCTGCCGCCGAAGGTCGCGCTGCCGATCCCGCTCTCGTACGGCACCGCCTATTGCGGCCTGGTCT
GGCGTTGCGCGCTGACGCCGCAGGACACCCTGCTGGTGCTCGGCGCTGGCGCTGGCGTCGGACTCGCGGCGGTGGAGATC
GGGCGGCAACTTGGGGCGACCGTGGTTGCCTGCGCCAGCACCGAGGCAAAACGCGCCGACGCGCTGCGCCGCGGGGCCAC
GCACGCGGTTGCGCCCCAGGACCTCGCCGCTCAAGTCAAGGCACTTACCGGTGGCCGTGGCGCGGATGTGGTGGTGGACC
CGGTCGGCGGCGACCTGTTCGGCCAGGCGCTGCGCGCCGCAGCGCCGAACGCGCGCATTCTTAGCATCGGCTTTGCCAGC
GGGTCCATCCCGCAGGCGCCGGTCAATCTGCTACTGGTCAAGAACCTGACGCTGCACGGCTTCTTCTTCGGCCGATACAT
CGGCTGGACGCCGTCCGACGAGCGCGCCGAGCACGCCCCGGCGTTGCAGCAGGTCATGTCCACCCTGTTTCAGTGGGCTG
CGGAAGGGAAGCTGGAGCCGACCGTGTCCGCTGTCTATCCGATCACCGGCCTGGGGGATGCCCTCGCCGCGCTGGAATCC
CGCAAGGTTGTTGGCAAGGTGGCAATAAAAATCAAGGAGACAGAGACATGA

Upstream 100 bases:

>100_bases
TGCTGCAGGAAGCCGGTTTCGGCAGCCACGCCATCGACGAATGGCTGCGGCTAGGCGTGGTGCGACAGGCAACGGCCACG
TCGGCGAAGGCGATGGCATG

Downstream 100 bases:

>100_bases
ATCATCCATCTACAAAGACGCCGGCCTGGTCACGGCTGCATGTTGCGCTGGCAGTCGTGGGAACGGCCTTCGCCATGCTG
CCCGCCGTTGGGTCCGCGCA

Product: putative Zinc-dependent dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MKALVCKQFGGVEDVELATVSEPALADPHAVTIEVEFASVSHATGLMIAGQYQRRPPLPFVPGTEAVGRVVACGKAVTRL
RPGDRVVAIADWGCYAERFTVPEYTVYPVPDSLPPKVALPIPLSYGTAYCGLVWRCALTPQDTLLVLGAGAGVGLAAVEI
GRQLGATVVACASTEAKRADALRRGATHAVAPQDLAAQVKALTGGRGADVVVDPVGGDLFGQALRAAAPNARILSIGFAS
GSIPQAPVNLLLVKNLTLHGFFFGRYIGWTPSDERAEHAPALQQVMSTLFQWAAEGKLEPTVSAVYPITGLGDALAALES
RKVVGKVAIKIKETET

Sequences:

>Translated_336_residues
MKALVCKQFGGVEDVELATVSEPALADPHAVTIEVEFASVSHATGLMIAGQYQRRPPLPFVPGTEAVGRVVACGKAVTRL
RPGDRVVAIADWGCYAERFTVPEYTVYPVPDSLPPKVALPIPLSYGTAYCGLVWRCALTPQDTLLVLGAGAGVGLAAVEI
GRQLGATVVACASTEAKRADALRRGATHAVAPQDLAAQVKALTGGRGADVVVDPVGGDLFGQALRAAAPNARILSIGFAS
GSIPQAPVNLLLVKNLTLHGFFFGRYIGWTPSDERAEHAPALQQVMSTLFQWAAEGKLEPTVSAVYPITGLGDALAALES
RKVVGKVAIKIKETET
>Mature_336_residues
MKALVCKQFGGVEDVELATVSEPALADPHAVTIEVEFASVSHATGLMIAGQYQRRPPLPFVPGTEAVGRVVACGKAVTRL
RPGDRVVAIADWGCYAERFTVPEYTVYPVPDSLPPKVALPIPLSYGTAYCGLVWRCALTPQDTLLVLGAGAGVGLAAVEI
GRQLGATVVACASTEAKRADALRRGATHAVAPQDLAAQVKALTGGRGADVVVDPVGGDLFGQALRAAAPNARILSIGFAS
GSIPQAPVNLLLVKNLTLHGFFFGRYIGWTPSDERAEHAPALQQVMSTLFQWAAEGKLEPTVSAVYPITGLGDALAALES
RKVVGKVAIKIKETET

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI18379349, Length=349, Percent_Identity=26.647564469914, Blast_Score=121, Evalue=9e-28,
Organism=Homo sapiens, GI194239674, Length=317, Percent_Identity=26.813880126183, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI13236495, Length=317, Percent_Identity=26.813880126183, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI194239676, Length=215, Percent_Identity=30.2325581395349, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI24308257, Length=354, Percent_Identity=25.7062146892655, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI22538446, Length=336, Percent_Identity=24.1071428571429, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI22538444, Length=336, Percent_Identity=24.1071428571429, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI67078406, Length=284, Percent_Identity=28.5211267605634, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI67078404, Length=300, Percent_Identity=27.6666666666667, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI41872631, Length=311, Percent_Identity=26.0450160771704, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI28557745, Length=262, Percent_Identity=28.6259541984733, Blast_Score=76, Evalue=5e-14,
Organism=Escherichia coli, GI1790485, Length=318, Percent_Identity=28.6163522012579, Blast_Score=86, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17536829, Length=302, Percent_Identity=24.8344370860927, Blast_Score=71, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17507255, Length=187, Percent_Identity=29.9465240641711, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319520, Length=345, Percent_Identity=26.9565217391304, Blast_Score=100, Evalue=3e-22,
Organism=Drosophila melanogaster, GI19920632, Length=346, Percent_Identity=23.6994219653179, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI221330659, Length=346, Percent_Identity=23.6994219653179, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24581345, Length=283, Percent_Identity=24.3816254416961, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 35112; Mature: 35112

Theoretical pI: Translated: 7.42; Mature: 7.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALVCKQFGGVEDVELATVSEPALADPHAVTIEVEFASVSHATGLMIAGQYQRRPPLPF
CCCEEEHHCCCCCCEEEEECCCCCCCCCCEEEEEEEEECCCCCCEEEEECCCCCCCCCCC
VPGTEAVGRVVACGKAVTRLRPGDRVVAIADWGCYAERFTVPEYTVYPVPDSLPPKVALP
CCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHEECCCCEEEEECCCCCCCCEEEE
IPLSYGTAYCGLVWRCALTPQDTLLVLGAGAGVGLAAVEIGRQLGATVVACASTEAKRAD
EECCCCCHHHHHHEEEECCCCCEEEEEECCCCCCHHHHHHHHHHCCEEEEECCCCHHHHH
ALRRGATHAVAPQDLAAQVKALTGGRGADVVVDPVGGDLFGQALRAAAPNARILSIGFAS
HHHHCCCCCCCCHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHCCCCCEEEEEEECC
GSIPQAPVNLLLVKNLTLHGFFFGRYIGWTPSDERAEHAPALQQVMSTLFQWAAEGKLEP
CCCCCCCEEEEEEECCEEEEEEEHHCCCCCCCCCHHHCCHHHHHHHHHHHHHHHCCCCCC
TVSAVYPITGLGDALAALESRKVVGKVAIKIKETET
CCEEEECCCCCHHHHHHHHHHHEEEEEEEEEEECCC
>Mature Secondary Structure
MKALVCKQFGGVEDVELATVSEPALADPHAVTIEVEFASVSHATGLMIAGQYQRRPPLPF
CCCEEEHHCCCCCCEEEEECCCCCCCCCCEEEEEEEEECCCCCCEEEEECCCCCCCCCCC
VPGTEAVGRVVACGKAVTRLRPGDRVVAIADWGCYAERFTVPEYTVYPVPDSLPPKVALP
CCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHEECCCCEEEEECCCCCCCCEEEE
IPLSYGTAYCGLVWRCALTPQDTLLVLGAGAGVGLAAVEIGRQLGATVVACASTEAKRAD
EECCCCCHHHHHHEEEECCCCCEEEEEECCCCCCHHHHHHHHHHCCEEEEECCCCHHHHH
ALRRGATHAVAPQDLAAQVKALTGGRGADVVVDPVGGDLFGQALRAAAPNARILSIGFAS
HHHHCCCCCCCCHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHCCCCCEEEEEEECC
GSIPQAPVNLLLVKNLTLHGFFFGRYIGWTPSDERAEHAPALQQVMSTLFQWAAEGKLEP
CCCCCCCEEEEEEECCEEEEEEEHHCCCCCCCCCHHHCCHHHHHHHHHHHHHHHCCCCCC
TVSAVYPITGLGDALAALESRKVVGKVAIKIKETET
CCEEEECCCCCHHHHHHHHHHHEEEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA