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The map label for this gene is arnA [H]

Identifier: 94313749

GI number: 94313749

Start: 1479989

End: 1481047

Strand: Reverse

Name: arnA [H]

Synonym: Rmet_4827

Alternate gene names: 94313749

Gene position: 1481047-1479989 (Counterclockwise)

Preceding gene: 94313750

Following gene: 94313748

Centisome position: 57.4

GC content: 62.42

Gene sequence:

>1059_bases
ATGCAGCAGAAGCGAGTCCTGATTCTTGGCATCAACGGCTTCATCGGCCACCACCTGACGCGCCGCATCCTGGAAACGAC
GCAATGGGAGGTCTACGGCATGGATATGTCGTCGGACCGCCTGGGCGATCTGGTGAACCACCCGCGCATGCACTTCTTCG
AGGGTGACATCACCATCAACAAGGAGTGGATCGAGTACAACATCCGCAAGTGCGATGTGGTGCTGCCGCTGGTGGCCATC
GCCACGCCGGCCACGTACGTGCGCGAGCCGCTGCGCGTGTTCGAACTGGACTTCGAGGCCAACCTGCCGATCGTGCGCGC
CGCGGTGAAGTACGGCAAGCATCTGGTGTTCCCGTCGACCTCGGAGGTGTACGGCATGTGCGCCGACGAAGAGTTCGACC
CGGAAGCCTCGCCGCTGATCTACGGCCCGATCAACAAGCCGCGCTGGATCTACGCCTGCTCCAAGCAGCTGATGGACCGC
GTGATCCACGCCTACGGGATGCAGGAAGGGCTGAACTACACGCTGTTCCGTCCGTTCAACTGGATCGGCGCGGGGCTGGA
CTCGATTTTCGAATCGAAGGAAGGTTCGTCGCGGGTGGTCACGCAGTTCCTGGGCCATATCGTGCGTGGCGAGCCGATCA
AGCTGGTGGACGGTGGCGCGCAGCAGCGTGCGTTCGCCGATATTTCGGACGGCATCTCGGCGCTGATGCGCATCATCGAG
AACAAGGACGGCGTGGCCAACGGCAAGATCTTCAACATCGGTAACCCGGGCAACATCCACTCGGTGCGTGAGCTGGCGGA
GATGATGCTGAAGATGGCGGCCGAGTATCCGGAGTACGCCGAGGAAGCGCGCAAGACGAAGATCGTGGAGACGTCGTCGG
GCGACTTCTACGGCAAGGGCTATCAGGACGTGCAGCACCGCGTGCCGAAGATCGACAACACGATCGGGGAACTGGGCTGG
AAGCCGGAGGTGTCGATGGAGCAGGCGCTGCGCCGGATCTTCGAGGCGTATCGCGACAAGGTGGTCGAGGCACGCACGCT
GGTCGACGCCAGCAACTGA

Upstream 100 bases:

>100_bases
CGAACGTGGCATCGCTTGCCGGGCCCCAGTAAAACCTGCTCCGAATAACTCCCCGGCTGGCTTCAGGTCGGTCACTATCA
ATTTGGTTTCATATATATCC

Downstream 100 bases:

>100_bases
GCGTCGCCCCGGACGGGGTGCGGCAGGCCATCAAAGAGGCTGCCGGGCCCCGGTTTTCGGGATGCCGGCGCGCACCCGCA
CGGCTTGTGGACTTGCCAGC

Product: NAD-dependent epimerase/dehydratase family protein

Products: NA

Alternate protein names: UDP-4-amino-4-deoxy-L-arabinose formyltransferase; ArnAFT; UDP-L-Ara4N formyltransferase; UDP-glucuronic acid oxidase, UDP-4-keto-hexauronic acid decarboxylating; ArnADH; UDP-GlcUA decarboxylase; UDP-glucuronic acid dehydrogenase [H]

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MQQKRVLILGINGFIGHHLTRRILETTQWEVYGMDMSSDRLGDLVNHPRMHFFEGDITINKEWIEYNIRKCDVVLPLVAI
ATPATYVREPLRVFELDFEANLPIVRAAVKYGKHLVFPSTSEVYGMCADEEFDPEASPLIYGPINKPRWIYACSKQLMDR
VIHAYGMQEGLNYTLFRPFNWIGAGLDSIFESKEGSSRVVTQFLGHIVRGEPIKLVDGGAQQRAFADISDGISALMRIIE
NKDGVANGKIFNIGNPGNIHSVRELAEMMLKMAAEYPEYAEEARKTKIVETSSGDFYGKGYQDVQHRVPKIDNTIGELGW
KPEVSMEQALRRIFEAYRDKVVEARTLVDASN

Sequences:

>Translated_352_residues
MQQKRVLILGINGFIGHHLTRRILETTQWEVYGMDMSSDRLGDLVNHPRMHFFEGDITINKEWIEYNIRKCDVVLPLVAI
ATPATYVREPLRVFELDFEANLPIVRAAVKYGKHLVFPSTSEVYGMCADEEFDPEASPLIYGPINKPRWIYACSKQLMDR
VIHAYGMQEGLNYTLFRPFNWIGAGLDSIFESKEGSSRVVTQFLGHIVRGEPIKLVDGGAQQRAFADISDGISALMRIIE
NKDGVANGKIFNIGNPGNIHSVRELAEMMLKMAAEYPEYAEEARKTKIVETSSGDFYGKGYQDVQHRVPKIDNTIGELGW
KPEVSMEQALRRIFEAYRDKVVEARTLVDASN
>Mature_352_residues
MQQKRVLILGINGFIGHHLTRRILETTQWEVYGMDMSSDRLGDLVNHPRMHFFEGDITINKEWIEYNIRKCDVVLPLVAI
ATPATYVREPLRVFELDFEANLPIVRAAVKYGKHLVFPSTSEVYGMCADEEFDPEASPLIYGPINKPRWIYACSKQLMDR
VIHAYGMQEGLNYTLFRPFNWIGAGLDSIFESKEGSSRVVTQFLGHIVRGEPIKLVDGGAQQRAFADISDGISALMRIIE
NKDGVANGKIFNIGNPGNIHSVRELAEMMLKMAAEYPEYAEEARKTKIVETSSGDFYGKGYQDVQHRVPKIDNTIGELGW
KPEVSMEQALRRIFEAYRDKVVEARTLVDASN

Specific function: Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabin

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the sugar epimerase family. UDP-glucuronic acid decarboxylase subfamily [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=344, Percent_Identity=27.6162790697674, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI7657641, Length=345, Percent_Identity=23.4782608695652, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1788589, Length=338, Percent_Identity=55.9171597633136, Blast_Score=398, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17539532, Length=348, Percent_Identity=23.8505747126437, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI21356223, Length=361, Percent_Identity=24.6537396121884, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR021168
- InterPro:   IPR001509
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase; PF02911 Formyl_trans_C; PF00551 Formyl_trans_N [H]

EC number: =2.1.2.13; =1.1.1.305 [H]

Molecular weight: Translated: 39922; Mature: 39922

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQKRVLILGINGFIGHHLTRRILETTQWEVYGMDMSSDRLGDLVNHPRMHFFEGDITIN
CCCCEEEEEECCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHCCCCCEEEECCEEEE
KEWIEYNIRKCDVVLPLVAIATPATYVREPLRVFELDFEANLPIVRAAVKYGKHLVFPST
HHHHHCCCHHHHHHHHHHHHHCCHHHHHCCHHHEEECCCCCCHHHHHHHHHCCEEECCCC
SEVYGMCADEEFDPEASPLIYGPINKPRWIYACSKQLMDRVIHAYGMQEGLNYTLFRPFN
HHHHEECCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCHH
WIGAGLDSIFESKEGSSRVVTQFLGHIVRGEPIKLVDGGAQQRAFADISDGISALMRIIE
HHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHH
NKDGVANGKIFNIGNPGNIHSVRELAEMMLKMAAEYPEYAEEARKTKIVETSSGDFYGKG
CCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHEEEECCCCCCCCCC
YQDVQHRVPKIDNTIGELGWKPEVSMEQALRRIFEAYRDKVVEARTLVDASN
HHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQQKRVLILGINGFIGHHLTRRILETTQWEVYGMDMSSDRLGDLVNHPRMHFFEGDITIN
CCCCEEEEEECCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHCCCCCEEEECCEEEE
KEWIEYNIRKCDVVLPLVAIATPATYVREPLRVFELDFEANLPIVRAAVKYGKHLVFPST
HHHHHCCCHHHHHHHHHHHHHCCHHHHHCCHHHEEECCCCCCHHHHHHHHHCCEEECCCC
SEVYGMCADEEFDPEASPLIYGPINKPRWIYACSKQLMDRVIHAYGMQEGLNYTLFRPFN
HHHHEECCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCHH
WIGAGLDSIFESKEGSSRVVTQFLGHIVRGEPIKLVDGGAQQRAFADISDGISALMRIIE
HHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHH
NKDGVANGKIFNIGNPGNIHSVRELAEMMLKMAAEYPEYAEEARKTKIVETSSGDFYGKG
CCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHEEEECCCCCCCCCC
YQDVQHRVPKIDNTIGELGWKPEVSMEQALRRIFEAYRDKVVEARTLVDASN
HHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA