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The map label for this gene is qor [H]

Identifier: 94313550

GI number: 94313550

Start: 1257042

End: 1258280

Strand: Direct

Name: qor [H]

Synonym: Rmet_4628

Alternate gene names: 94313550

Gene position: 1257042-1258280 (Clockwise)

Preceding gene: 94313546

Following gene: 94313551

Centisome position: 48.72

GC content: 65.62

Gene sequence:

>1239_bases
ATGCGGGAGCGCGGTCCGGTTCGGCACCTCGCCCACATGGGGCTCCCGATTTTACCAAGTGGCGGGTGCGCCCATTTGAT
GGATGGGGGCAGTCGCTTGACCATTCGTCCCACACCTGGCGCTGGCGCGTTTTGCACGATTCTGTCGCGCATTGTCAGGC
AGTGGACCCGCCAGGGCAGGACAATCGCGTTCAAACCGCCGGCTCGATGGCACCGGCAATGGGCCGCTAATGGGCCGCGC
GGTGGGCGATTCACAGGAGACATCAAGATGGCAAAGGCTGTTCGTTTCTACGAGACCGGTGGTCCCGAAGTCCTGAAGTT
CGAGAACGTCGAAGTCGGAGACCCGGGTCCCGGTCAGGCGCGGGTGCGGCACACCTATATCGCCGTGAACTTCATCGACA
TCTACTTCCGCACCGGCCACTACCCGCTGGAGCTGCCGAACGGACTGGGCTCCGACGCTGTGGGCGTAGTCGAGGCGGTG
GGTCCCGGCGTGACCGATATTCGCGTTGGTGACCGCGTCGGATACCTGCTCGGGCCGCAGGGCGCTTACTCGGACGTGCG
CGTGATGCCTGCCGACGTGCTGATTCCGCTGCCGGATGGCATTGCCGACCGCACGGCCGCCACGCTGATGATGAAAGGCA
TGACCGCGCAGTACCTGTTCCGCCAGGTCTATCCCCTCAAGGGTGGCGAGACGATCCTCTATCACGCCGCAGCCGGCGGC
GTGGGTCTGATTGCCTGCCAGTGGGCGCGCGCGCTTGGCGTGACGATGATCGGCACCGTCAGCTCCGACGAAAAGGCCGA
GATCGCCAAGGCCAATGGCTGCACACATACCATCGTCACCTCGCGGGAGAACATCGCCGAGCGCGTCAAGGCGCTCACCG
ATGGCAAGGGTGTGCCGGTGGTGTTCGATTCCATCGGCAAATCCACGCTCGAGGCGTCGCTCGACAGCTTGCAGGTGCGC
GGCACGCTGGTGAGCAATGGCACGACCTCGGGCCCGGTCGAGATCGACAGCCGGGTGATCGCCCGCAAGGGTTCGCTCTG
GGTCACGCGCCCGGCCATGATCCACTACGCCACGCCGCGCTCCCACATGCTGGCGATGGCGGCGGAGGTGTTCGACATGG
TCATGGCGGGCAAGATCCACAACGAGCCCCGCCAGACGTTCGCTCTGGCAGAGGCTGCGCTGGCCCACCAGGCGCTGGAA
TCGCGCCAGACCAGTGGCGCCACGGTGCTGGTGCCGTAG

Upstream 100 bases:

>100_bases
GTGATCATCCGCGATCACGACGGAGATGGTGTCTGGTGGCATGTACGTTGGGTTTTTCCGCACCCCGGACAAGATCCGGG
AGGGTTTCTGCGTCTACAAC

Downstream 100 bases:

>100_bases
CCGTACGGGGTGGCGTCCGGCGTTTGCCACGCCACCCAACACGGCCTTCAGGTGTGCTCAAATTGAGGCTCGGGCGGCAG
GATGCCCGAGCCTTCCTGTC

Product: Quinone oxidoreductase, NADPH-dependent

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MRERGPVRHLAHMGLPILPSGGCAHLMDGGSRLTIRPTPGAGAFCTILSRIVRQWTRQGRTIAFKPPARWHRQWAANGPR
GGRFTGDIKMAKAVRFYETGGPEVLKFENVEVGDPGPGQARVRHTYIAVNFIDIYFRTGHYPLELPNGLGSDAVGVVEAV
GPGVTDIRVGDRVGYLLGPQGAYSDVRVMPADVLIPLPDGIADRTAATLMMKGMTAQYLFRQVYPLKGGETILYHAAAGG
VGLIACQWARALGVTMIGTVSSDEKAEIAKANGCTHTIVTSRENIAERVKALTDGKGVPVVFDSIGKSTLEASLDSLQVR
GTLVSNGTTSGPVEIDSRVIARKGSLWVTRPAMIHYATPRSHMLAMAAEVFDMVMAGKIHNEPRQTFALAEAALAHQALE
SRQTSGATVLVP

Sequences:

>Translated_412_residues
MRERGPVRHLAHMGLPILPSGGCAHLMDGGSRLTIRPTPGAGAFCTILSRIVRQWTRQGRTIAFKPPARWHRQWAANGPR
GGRFTGDIKMAKAVRFYETGGPEVLKFENVEVGDPGPGQARVRHTYIAVNFIDIYFRTGHYPLELPNGLGSDAVGVVEAV
GPGVTDIRVGDRVGYLLGPQGAYSDVRVMPADVLIPLPDGIADRTAATLMMKGMTAQYLFRQVYPLKGGETILYHAAAGG
VGLIACQWARALGVTMIGTVSSDEKAEIAKANGCTHTIVTSRENIAERVKALTDGKGVPVVFDSIGKSTLEASLDSLQVR
GTLVSNGTTSGPVEIDSRVIARKGSLWVTRPAMIHYATPRSHMLAMAAEVFDMVMAGKIHNEPRQTFALAEAALAHQALE
SRQTSGATVLVP
>Mature_412_residues
MRERGPVRHLAHMGLPILPSGGCAHLMDGGSRLTIRPTPGAGAFCTILSRIVRQWTRQGRTIAFKPPARWHRQWAANGPR
GGRFTGDIKMAKAVRFYETGGPEVLKFENVEVGDPGPGQARVRHTYIAVNFIDIYFRTGHYPLELPNGLGSDAVGVVEAV
GPGVTDIRVGDRVGYLLGPQGAYSDVRVMPADVLIPLPDGIADRTAATLMMKGMTAQYLFRQVYPLKGGETILYHAAAGG
VGLIACQWARALGVTMIGTVSSDEKAEIAKANGCTHTIVTSRENIAERVKALTDGKGVPVVFDSIGKSTLEASLDSLQVR
GTLVSNGTTSGPVEIDSRVIARKGSLWVTRPAMIHYATPRSHMLAMAAEVFDMVMAGKIHNEPRQTFALAEAALAHQALE
SRQTSGATVLVP

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=264, Percent_Identity=32.9545454545455, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI13236495, Length=264, Percent_Identity=32.9545454545455, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI194239676, Length=209, Percent_Identity=35.4066985645933, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI22538446, Length=262, Percent_Identity=31.2977099236641, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI22538444, Length=262, Percent_Identity=31.2977099236641, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI28557745, Length=269, Percent_Identity=28.996282527881, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI18379349, Length=215, Percent_Identity=33.0232558139535, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI24308257, Length=256, Percent_Identity=28.125, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI197927207, Length=123, Percent_Identity=34.1463414634146, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI67078404, Length=243, Percent_Identity=26.7489711934156, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1790485, Length=327, Percent_Identity=44.3425076452599, Blast_Score=270, Evalue=9e-74,
Organism=Caenorhabditis elegans, GI17507255, Length=320, Percent_Identity=25.625, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17556000, Length=341, Percent_Identity=28.4457478005865, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17536829, Length=294, Percent_Identity=25.1700680272109, Blast_Score=69, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6319520, Length=323, Percent_Identity=34.984520123839, Blast_Score=176, Evalue=8e-45,
Organism=Drosophila melanogaster, GI45550423, Length=326, Percent_Identity=26.9938650306748, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 44136; Mature: 44136

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRERGPVRHLAHMGLPILPSGGCAHLMDGGSRLTIRPTPGAGAFCTILSRIVRQWTRQGR
CCCCCHHHHHHHCCCCCCCCCCCHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCC
TIAFKPPARWHRQWAANGPRGGRFTGDIKMAKAVRFYETGGPEVLKFENVEVGDPGPGQA
EEEECCCHHHHHHHCCCCCCCCEEECCEEHHHEEEEEECCCCCEEEECCEECCCCCCCCC
RVRHTYIAVNFIDIYFRTGHYPLELPNGLGSDAVGVVEAVGPGVTDIRVGDRVGYLLGPQ
EEEEEEEEEEEEEEEEECCCCCEECCCCCCCCHHHHHHHCCCCCEEEEECCCCCEEECCC
GAYSDVRVMPADVLIPLPDGIADRTAATLMMKGMTAQYLFRQVYPLKGGETILYHAAAGG
CCCCCCEEECCEEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCEEEEEECCCC
VGLIACQWARALGVTMIGTVSSDEKAEIAKANGCTHTIVTSRENIAERVKALTDGKGVPV
CCHHHHHHHHHCCEEEEEECCCCCCHHHHHCCCCEEEEEECHHHHHHHHHHHHCCCCCCE
VFDSIGKSTLEASLDSLQVRGTLVSNGTTSGPVEIDSRVIARKGSLWVTRPAMIHYATPR
EEHHCCHHHHHHHHHHEEEEEEEEECCCCCCCEEECCEEEEECCCEEEECCEEEEEECCH
SHMLAMAAEVFDMVMAGKIHNEPRQTFALAEAALAHQALESRQTSGATVLVP
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEC
>Mature Secondary Structure
MRERGPVRHLAHMGLPILPSGGCAHLMDGGSRLTIRPTPGAGAFCTILSRIVRQWTRQGR
CCCCCHHHHHHHCCCCCCCCCCCHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCC
TIAFKPPARWHRQWAANGPRGGRFTGDIKMAKAVRFYETGGPEVLKFENVEVGDPGPGQA
EEEECCCHHHHHHHCCCCCCCCEEECCEEHHHEEEEEECCCCCEEEECCEECCCCCCCCC
RVRHTYIAVNFIDIYFRTGHYPLELPNGLGSDAVGVVEAVGPGVTDIRVGDRVGYLLGPQ
EEEEEEEEEEEEEEEEECCCCCEECCCCCCCCHHHHHHHCCCCCEEEEECCCCCEEECCC
GAYSDVRVMPADVLIPLPDGIADRTAATLMMKGMTAQYLFRQVYPLKGGETILYHAAAGG
CCCCCCEEECCEEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCEEEEEECCCC
VGLIACQWARALGVTMIGTVSSDEKAEIAKANGCTHTIVTSRENIAERVKALTDGKGVPV
CCHHHHHHHHHCCEEEEEECCCCCCHHHHHCCCCEEEEEECHHHHHHHHHHHHCCCCCCE
VFDSIGKSTLEASLDSLQVRGTLVSNGTTSGPVEIDSRVIARKGSLWVTRPAMIHYATPR
EEHHCCHHHHHHHHHHEEEEEEEEECCCCCCCEEECCEEEEECCCEEEECCEEEEEECCH
SHMLAMAAEVFDMVMAGKIHNEPRQTFALAEAALAHQALESRQTSGATVLVP
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]