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The map label for this gene is virS [H]

Identifier: 94313551

GI number: 94313551

Start: 1258398

End: 1259489

Strand: Direct

Name: virS [H]

Synonym: Rmet_4629

Alternate gene names: 94313551

Gene position: 1258398-1259489 (Clockwise)

Preceding gene: 94313550

Following gene: 94313553

Centisome position: 48.77

GC content: 66.94

Gene sequence:

>1092_bases
ATGACAGCCCCCTCCATCCAGCAATTCAGACTCGTCCGCAGCGCCAGCCTGAACGGCTACATCGAACTGGTGAAGTCGCT
CGGGTACGATCCGCGCGCGTTCCTGCGGGGCGTGGGGCTGTCGGCCCGGCTGCTCGAGAATCCCGAGACATTGATCCCCA
GCCCCGCCGTGCGCGAATTGCTCGAAGTCACCGCGCAGGTCACCGGCGTGGAAGACTTTGCATTGCGCCTGGCGGCGCGG
CGCACGTTCTCCAACCTCGGGCCAATCAGCCTGGTGCTCAAGGAAGCCGCCACGCCGCGTGAGGCGCTGGACACGCTCTG
CCGCTATCTGAAGTTGCTTAGCGCCGCGCTGATCACGCGCGTGGAGGACGTTGGCGACGCGGTGATCATCCGCGAGGATC
TGCTGCCCACCCCCGGGCTGTCGTCTCGTCAGGCGCTGGAACTGGCGATGGGCGTGACCTTCCGCATGTTGCGCGAGCTG
ATTGGCCCCCGGTGGCGCCCGCAGCAGGTCTGCTTCATGCACCGTCCGCCGGCCGATCTGTCCCCATACCGTGCGTTCTT
CGGGCGCAACCCGATGTTCAACCAACCGTTCAACGGCATGGTCTGCGCGGCGGCCGACCTGAGCATGTCACGGATGCCCG
ATGACCCCGGCGTGGCACGCTTCGCGCGCGATTACCTGGAGGCGGCGCTGCGGCACCGCGAGATCGGCATCCGAGACTCC
TGCCGCGAACTGGTCCAGGCGCTGCTTCCCGGCGGGCGCTGTACCGCCGATCAGGTGGCACGTCATCTGGGTGTCGATCG
CCGCACCTTGCACCGCTACCTGAGCGCCGAAGGCCTGACGTTTTCGACCCTGCTCCACGAGGTGCGGTCCGAACTGGTCA
TGCGCCACCTGCTGGAAAGCGATCTGCCGATGGGGGAAGTGGCGGGCCTGCTAGGATTCTCGGCACAGAGCAGCTTCAGC
CACTGGTTCCAGACCGTATTCGGGTGCAGTGCCACAGACTGGCGCAGGGTCCAATCCGCGCAGCCCGGGAAGTCAGGGAA
ATCCGGGCAGTCCGCTGCCGCAACCGGCCGACGGGCGCCTTCGCGCGTCTGA

Upstream 100 bases:

>100_bases
CGGCGTTTGCCACGCCACCCAACACGGCCTTCAGGTGTGCTCAAATTGAGGCTCGGGCGGCAGGATGCCCGAGCCTTCCT
GTCTGGTCAGGATGCAAACA

Downstream 100 bases:

>100_bases
TGCGCGCCTGACGTACCCCAGCGCGCGAAAGGGCCGCCCTGCCCCTTCGCGCCGTCCGTCTTACTCCGGCACGAAGTGAA
TCGAATGCAGCAGCTTGCCC

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MTAPSIQQFRLVRSASLNGYIELVKSLGYDPRAFLRGVGLSARLLENPETLIPSPAVRELLEVTAQVTGVEDFALRLAAR
RTFSNLGPISLVLKEAATPREALDTLCRYLKLLSAALITRVEDVGDAVIIREDLLPTPGLSSRQALELAMGVTFRMLREL
IGPRWRPQQVCFMHRPPADLSPYRAFFGRNPMFNQPFNGMVCAAADLSMSRMPDDPGVARFARDYLEAALRHREIGIRDS
CRELVQALLPGGRCTADQVARHLGVDRRTLHRYLSAEGLTFSTLLHEVRSELVMRHLLESDLPMGEVAGLLGFSAQSSFS
HWFQTVFGCSATDWRRVQSAQPGKSGKSGQSAAATGRRAPSRV

Sequences:

>Translated_363_residues
MTAPSIQQFRLVRSASLNGYIELVKSLGYDPRAFLRGVGLSARLLENPETLIPSPAVRELLEVTAQVTGVEDFALRLAAR
RTFSNLGPISLVLKEAATPREALDTLCRYLKLLSAALITRVEDVGDAVIIREDLLPTPGLSSRQALELAMGVTFRMLREL
IGPRWRPQQVCFMHRPPADLSPYRAFFGRNPMFNQPFNGMVCAAADLSMSRMPDDPGVARFARDYLEAALRHREIGIRDS
CRELVQALLPGGRCTADQVARHLGVDRRTLHRYLSAEGLTFSTLLHEVRSELVMRHLLESDLPMGEVAGLLGFSAQSSFS
HWFQTVFGCSATDWRRVQSAQPGKSGKSGQSAAATGRRAPSRV
>Mature_362_residues
TAPSIQQFRLVRSASLNGYIELVKSLGYDPRAFLRGVGLSARLLENPETLIPSPAVRELLEVTAQVTGVEDFALRLAARR
TFSNLGPISLVLKEAATPREALDTLCRYLKLLSAALITRVEDVGDAVIIREDLLPTPGLSSRQALELAMGVTFRMLRELI
GPRWRPQQVCFMHRPPADLSPYRAFFGRNPMFNQPFNGMVCAAADLSMSRMPDDPGVARFARDYLEAALRHREIGIRDSC
RELVQALLPGGRCTADQVARHLGVDRRTLHRYLSAEGLTFSTLLHEVRSELVMRHLLESDLPMGEVAGLLGFSAQSSFSH
WFQTVFGCSATDWRRVQSAQPGKSGKSGQSAAATGRRAPSRV

Specific function: May have a role in the regulation of proteins necessary for virulence [H]

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 40100; Mature: 39969

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPSIQQFRLVRSASLNGYIELVKSLGYDPRAFLRGVGLSARLLENPETLIPSPAVREL
CCCCCHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHCCCHHHHHCCCHHCCCCHHHHHH
LEVTAQVTGVEDFALRLAARRTFSNLGPISLVLKEAATPREALDTLCRYLKLLSAALITR
HHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
VEDVGDAVIIREDLLPTPGLSSRQALELAMGVTFRMLRELIGPRWRPQQVCFMHRPPADL
HHHHCCEEEEHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEECCCCCC
SPYRAFFGRNPMFNQPFNGMVCAAADLSMSRMPDDPGVARFARDYLEAALRHREIGIRDS
CHHHHHHCCCCCCCCCCCCEEEEHHHCHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHH
CRELVQALLPGGRCTADQVARHLGVDRRTLHRYLSAEGLTFSTLLHEVRSELVMRHLLES
HHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHC
DLPMGEVAGLLGFSAQSSFSHWFQTVFGCSATDWRRVQSAQPGKSGKSGQSAAATGRRAP
CCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCHHHHHCCCCC
SRV
CCC
>Mature Secondary Structure 
TAPSIQQFRLVRSASLNGYIELVKSLGYDPRAFLRGVGLSARLLENPETLIPSPAVREL
CCCCHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHCCCHHHHHCCCHHCCCCHHHHHH
LEVTAQVTGVEDFALRLAARRTFSNLGPISLVLKEAATPREALDTLCRYLKLLSAALITR
HHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
VEDVGDAVIIREDLLPTPGLSSRQALELAMGVTFRMLRELIGPRWRPQQVCFMHRPPADL
HHHHCCEEEEHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEECCCCCC
SPYRAFFGRNPMFNQPFNGMVCAAADLSMSRMPDDPGVARFARDYLEAALRHREIGIRDS
CHHHHHHCCCCCCCCCCCCEEEEHHHCHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHH
CRELVQALLPGGRCTADQVARHLGVDRRTLHRYLSAEGLTFSTLLHEVRSELVMRHLLES
HHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHC
DLPMGEVAGLLGFSAQSSFSHWFQTVFGCSATDWRRVQSAQPGKSGKSGQSAAATGRRAP
CCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCHHHHHCCCCC
SRV
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8472958; 9634230; 12218036 [H]