Click here to switch to the map view.

The map label for this gene is arnA [H]

Identifier: 94313514

GI number: 94313514

Start: 1211064

End: 1212116

Strand: Direct

Name: arnA [H]

Synonym: Rmet_4592

Alternate gene names: 94313514

Gene position: 1211064-1212116 (Clockwise)

Preceding gene: 94313513

Following gene: 94313515

Centisome position: 46.94

GC content: 61.92

Gene sequence:

>1053_bases
ATGAAAAAGGTCCTGATTCTTGGCGTCAATGGCTTCATCGGCCACCATCTGACGCGCCGCATCCTGGAAACGACGCAATG
GGAGGTCTACGGCATGGATATGTCGTCGGACCGCCTGGGCGATCTGGTGAACCACCCACGCATGCACTTCTTCGAGGGTG
ACATCACCATCAACAAGGAGTGGATCGAGTACAACATCCGCAAGTGCGATGTGGTGCTGCCGCTGGTGGCCATCGCCACG
CCGGCCACGTACGTGCGCGAGCCGCTGCGCGTGTTCGAACTGGACTTCGAGGCCAACCTGCCGATCGTGCGCGCCGCGGT
GAAGTACGGCAAGCATCTGGTGTTCCCGTCGACCTCGGAGGTGTACGGCATGTGCGCCGACGAAGAGTTCGACCCGGAAG
CCTCGCCGCTGATCTACGGCCCGATCAACAAGCCGCGCTGGATCTACGCCTGCTCCAAGCAGCTGATGGACCGCGTGATC
CACGCCTACGGGATGCAGGAAGGGCTGAACTACACGTTGTTCCGTCCGTTCAACTGGATCGGCGCCGGGCTGGACTCGAT
TTTCGAATCGAAGGAAGGTTCGTCGCGGGTGGTCACGCAGTTCCTGGGCCATATCGTGCGTGGCGAGCCGATCAAGCTGG
TGGACGGTGGCGCGCAGCAGCGTGCGTTCGCCGATATTTCGGACGGCATCTCGGCGCTGATGCGCATCATCGAGAACAAG
GACGGCGTGGCCAACGGCAAGATCTTCAACATTGGCAACCCGGGCAACATCCACTCGGTGCGTGAGCTGGCCGAGATGAT
GCTGAAGATGGCGGCCGAGTATCCGGAGTACGCCGAGGAAGCGCGCAAGACGAAGATCGTGGAGACGTCGTCGGGCGACT
TCTACGGCAAGGGCTATCAGGACGTGCAGCACCGCGTGCCGAAGATCGACAACACGATCGGGGAACTGGGCTGGAAGCCG
GAGGTGTCGATGGAGCAGGCGCTGCGCCGCATCTTCGAGGCGTATCGCGACAAGGTCGTCGAGGCACGCACGCTGGTGGA
CGCGGACAACTGA

Upstream 100 bases:

>100_bases
TGACGCAGTTGCTCGAAGGTCCGAACGCCGACAACGCGAGCCCGGTATCTGTACAAGTATTCCAAAACATCATTACTGCG
AAGTCCTAAGAGGAAAACCG

Downstream 100 bases:

>100_bases
TCGCTTCATGGCACGCATTGCGCTCAAGGTAGACGTGGACACGCTGCGCGGCACGCGCGAAGGCGTGCCCGCGCTGCTGT
CCATGCTGTCCGCCGCCGAG

Product: NAD-dependent epimerase/dehydratase family protein

Products: NA

Alternate protein names: UDP-4-amino-4-deoxy-L-arabinose formyltransferase; ArnAFT; UDP-L-Ara4N formyltransferase; UDP-glucuronic acid oxidase, UDP-4-keto-hexauronic acid decarboxylating; ArnADH; UDP-GlcUA decarboxylase; UDP-glucuronic acid dehydrogenase [H]

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MKKVLILGVNGFIGHHLTRRILETTQWEVYGMDMSSDRLGDLVNHPRMHFFEGDITINKEWIEYNIRKCDVVLPLVAIAT
PATYVREPLRVFELDFEANLPIVRAAVKYGKHLVFPSTSEVYGMCADEEFDPEASPLIYGPINKPRWIYACSKQLMDRVI
HAYGMQEGLNYTLFRPFNWIGAGLDSIFESKEGSSRVVTQFLGHIVRGEPIKLVDGGAQQRAFADISDGISALMRIIENK
DGVANGKIFNIGNPGNIHSVRELAEMMLKMAAEYPEYAEEARKTKIVETSSGDFYGKGYQDVQHRVPKIDNTIGELGWKP
EVSMEQALRRIFEAYRDKVVEARTLVDADN

Sequences:

>Translated_350_residues
MKKVLILGVNGFIGHHLTRRILETTQWEVYGMDMSSDRLGDLVNHPRMHFFEGDITINKEWIEYNIRKCDVVLPLVAIAT
PATYVREPLRVFELDFEANLPIVRAAVKYGKHLVFPSTSEVYGMCADEEFDPEASPLIYGPINKPRWIYACSKQLMDRVI
HAYGMQEGLNYTLFRPFNWIGAGLDSIFESKEGSSRVVTQFLGHIVRGEPIKLVDGGAQQRAFADISDGISALMRIIENK
DGVANGKIFNIGNPGNIHSVRELAEMMLKMAAEYPEYAEEARKTKIVETSSGDFYGKGYQDVQHRVPKIDNTIGELGWKP
EVSMEQALRRIFEAYRDKVVEARTLVDADN
>Mature_350_residues
MKKVLILGVNGFIGHHLTRRILETTQWEVYGMDMSSDRLGDLVNHPRMHFFEGDITINKEWIEYNIRKCDVVLPLVAIAT
PATYVREPLRVFELDFEANLPIVRAAVKYGKHLVFPSTSEVYGMCADEEFDPEASPLIYGPINKPRWIYACSKQLMDRVI
HAYGMQEGLNYTLFRPFNWIGAGLDSIFESKEGSSRVVTQFLGHIVRGEPIKLVDGGAQQRAFADISDGISALMRIIENK
DGVANGKIFNIGNPGNIHSVRELAEMMLKMAAEYPEYAEEARKTKIVETSSGDFYGKGYQDVQHRVPKIDNTIGELGWKP
EVSMEQALRRIFEAYRDKVVEARTLVDADN

Specific function: Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabin

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the sugar epimerase family. UDP-glucuronic acid decarboxylase subfamily [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=356, Percent_Identity=26.685393258427, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI7657641, Length=345, Percent_Identity=23.1884057971014, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI1788589, Length=335, Percent_Identity=56.4179104477612, Blast_Score=396, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17539532, Length=347, Percent_Identity=23.6311239193084, Blast_Score=97, Evalue=9e-21,
Organism=Drosophila melanogaster, GI21356223, Length=360, Percent_Identity=24.1666666666667, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR021168
- InterPro:   IPR001509
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase; PF02911 Formyl_trans_C; PF00551 Formyl_trans_N [H]

EC number: =2.1.2.13; =1.1.1.305 [H]

Molecular weight: Translated: 39652; Mature: 39652

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVLILGVNGFIGHHLTRRILETTQWEVYGMDMSSDRLGDLVNHPRMHFFEGDITINKE
CCEEEEEECCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHCCCCCEEEECCEEEEHH
WIEYNIRKCDVVLPLVAIATPATYVREPLRVFELDFEANLPIVRAAVKYGKHLVFPSTSE
HHHCCCHHHHHHHHHHHHHCCHHHHHCCHHHEEECCCCCCHHHHHHHHHCCEEECCCCHH
VYGMCADEEFDPEASPLIYGPINKPRWIYACSKQLMDRVIHAYGMQEGLNYTLFRPFNWI
HHEECCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHH
GAGLDSIFESKEGSSRVVTQFLGHIVRGEPIKLVDGGAQQRAFADISDGISALMRIIENK
HHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCC
DGVANGKIFNIGNPGNIHSVRELAEMMLKMAAEYPEYAEEARKTKIVETSSGDFYGKGYQ
CCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHEEEECCCCCCCCCCHH
DVQHRVPKIDNTIGELGWKPEVSMEQALRRIFEAYRDKVVEARTLVDADN
HHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKKVLILGVNGFIGHHLTRRILETTQWEVYGMDMSSDRLGDLVNHPRMHFFEGDITINKE
CCEEEEEECCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHCCCCCEEEECCEEEEHH
WIEYNIRKCDVVLPLVAIATPATYVREPLRVFELDFEANLPIVRAAVKYGKHLVFPSTSE
HHHCCCHHHHHHHHHHHHHCCHHHHHCCHHHEEECCCCCCHHHHHHHHHCCEEECCCCHH
VYGMCADEEFDPEASPLIYGPINKPRWIYACSKQLMDRVIHAYGMQEGLNYTLFRPFNWI
HHEECCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHH
GAGLDSIFESKEGSSRVVTQFLGHIVRGEPIKLVDGGAQQRAFADISDGISALMRIIENK
HHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCC
DGVANGKIFNIGNPGNIHSVRELAEMMLKMAAEYPEYAEEARKTKIVETSSGDFYGKGYQ
CCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHEEEECCCCCCCCCCHH
DVQHRVPKIDNTIGELGWKPEVSMEQALRRIFEAYRDKVVEARTLVDADN
HHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA