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The map label for this gene is yciR [C]

Identifier: 94313385

GI number: 94313385

Start: 1056769

End: 1058898

Strand: Direct

Name: yciR [C]

Synonym: Rmet_4460

Alternate gene names: 94313385

Gene position: 1056769-1058898 (Clockwise)

Preceding gene: 94313383

Following gene: 94313387

Centisome position: 40.96

GC content: 63.52

Gene sequence:

>2130_bases
ATGTCAGAATGCCGCCACCTCGAAGTCATCGCCCCATTCGAAGTCATCGCCCCCACCATGTTTCCCGCCAGTTACGACGC
GTTACTCGTCCTGTTTTCGGTCATTGTCGCCGTTCTCGCTTCCTATACCGCGCTGGACATGGCAGGGCGCATCTCCACCG
CGAGCGGCCGCTATGCGCGGCTGTGGCTGGCCGGCGGGGCAGTGGCCATGGGGCTTGGCATCTGGTCGATGCACTTCCTG
GGCATGTTGTCGTTCAGCCTGCCGATTCCGCTGGGCTACGACCCCGCCATCACGGCTGTCTCGCTGCTGATCGCCGTTGT
TGCCTCGGCATTCGCGCTGCGGCTCGTCTGCCTGGAGCATCTGCCGCGCAGGCGGCTGGCGCTTGGCGCGCTGGTGCTCG
GCGGGGCCGTAGCCAGCATGCATTACACGGGCATGGCGGCATTGCGCATGCAACCGGGCATTCAGTACGACCCGTGGTTG
TTTCTATTGTCGATCCTGATCGCCGTGGGGGCATCCGGGGCGGCGCTCTGGATTGCCTTCCGATTGCGGCGGCACATGCC
GCGCGTGCATCAACTGCGCTTTGGAGCGGCACTGGTGATGGGCGGCGCCGTCGCGGCGATGCACTACACCGGCATGGCCG
CGGCGAGGTTTCCTATCGGCAGTGTGTGTGGCGCAGCGGGCGGCGGGCTGCAGGGCAATACGCTGGCGCTGCCCATTCTC
GTGATCACGATCTGCGTCCTGGCCGTGGCGCTGATTACCTCGGTGCTCGACATGCGCCTGGAAATGCGCACGGCGGTGCT
GGCCGACGCGCTGGGCGTCGCGAACGAAGAGCTGGAATTCCTGGCGCTACACGACAAGCTCACCCATCTGCCGAACCGCG
TGCTGCTGGAAGACCGTTTCACGCTGGCGATTCAGGCAGCGGCCCGGCACCATGGCCGTTTTGCCGTGCTTTTCGTCGAT
CTGGATGGATTCAAGGGCGTCAACGATACCTACGGGCACCAGGTCGGCGACGGGCTGTTGGTGGAGATCGCCAATCGGCT
GCGGGCATCGGTTTCGTCGGAAGATACGATCGCGCGTGTCGGTGGCGATGAGTTCGTGCTGCTGGTGCACGTCGACGAAC
CTGAGGATGCGGGTGTCGTCGCCGGGAAGCTGATCGACGTGCTGCGCGAGCCCGCAAATGTGGCAGGCCACATGGTGCAC
GTCTCAGGCAGCATCGGCATTGCGATCTACCCCGTCGACGGACAGGATCAGGACGCGCTGATGACCAATGCCGACGCCGC
GATGTACCACGCGAAGGCATCAGGCCGGAACGCGAGCTACTTCTTCGAGCGGTCGATGAACCATCAGGCGCGGGCGCAGC
AGATGCTGATCCAGGACTTGCGGGCGGCCCTGAGAAACGGCCAATTGCAGTTGCACTATCAACCGAAGTTTTCGGCTGCT
GACAATGTGCTGGTAGGCGCCGAGGCGCTGCTGCGCTGGAATCATCCCGTGCAGGGCCTGCTGATGCCGGACCAGTTCAT
CACGCTGGCAGAGAAGACCGGGGCAATCGTGCCGATCGGGACGTGGGTACTCAACGAGGCGTGCCGGCAATTGGCGTTAT
GGCACGACATGGGGCACGCGCACTGGTCGATGGCGGTCAACCTTTCCGCGCTGCAGTTCTGCCATGCGGGCATGGTCGAG
TCGGTAGCCGAGGCGTTAGCGCGGCATAAGGTCGAGCCAAGACGATTGACGCTCGAGATTACGGAAACCACCGCCATGCG
CGATGTGGAGACCACGCTCGCGATCATGACCCAGCTCGACGAGATGGGCGTGCGGATTGCGATCGATGATTTCGGTACTG
GATATTCAAGCCTGCTGCATCTGAAGCGCATCCCAGCGAGCGAATTGAAGATCGACCGGGGATTCGTGCGCGATCTCGCG
GAAGACAGCGAGGATGCCGCGATCGTATCGGCCATCGTGGCGCTGGGCCGAACGCTGAATTTGCAGGTAGTGGCTGAGGG
CGTGGAAACGACCGCTCAGCGGTCGTTCCTGGCAGGTCTGGGGTGTGATGCGTTGCAGGGCTATCTACTTGGCAGGCCGA
TGCCTGCGGCGCAATTCACGGAGCTGGCGCTGGCCGATGTCGATGCGTGA

Upstream 100 bases:

>100_bases
AGCCCATGACGCCGAGCCCGAGGAATGCAACCCGCATGACTTTGCTCCGTGACTTCGAAGAGAGGCAAGAGTATAGGTCG
TTTGCGGGCAGTGGCGGTCG

Downstream 100 bases:

>100_bases
GCGTGTCATGACACGTCACGCATCGAGCGACATCCTGTATCAGGCCCCGTCGGTGAACACGTCGCGCTTGCCCGTTGCGC
TGAAGCCGCCGTCTGTGTAC

Product: Diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 709; Mature: 708

Protein sequence:

>709_residues
MSECRHLEVIAPFEVIAPTMFPASYDALLVLFSVIVAVLASYTALDMAGRISTASGRYARLWLAGGAVAMGLGIWSMHFL
GMLSFSLPIPLGYDPAITAVSLLIAVVASAFALRLVCLEHLPRRRLALGALVLGGAVASMHYTGMAALRMQPGIQYDPWL
FLLSILIAVGASGAALWIAFRLRRHMPRVHQLRFGAALVMGGAVAAMHYTGMAAARFPIGSVCGAAGGGLQGNTLALPIL
VITICVLAVALITSVLDMRLEMRTAVLADALGVANEELEFLALHDKLTHLPNRVLLEDRFTLAIQAAARHHGRFAVLFVD
LDGFKGVNDTYGHQVGDGLLVEIANRLRASVSSEDTIARVGGDEFVLLVHVDEPEDAGVVAGKLIDVLREPANVAGHMVH
VSGSIGIAIYPVDGQDQDALMTNADAAMYHAKASGRNASYFFERSMNHQARAQQMLIQDLRAALRNGQLQLHYQPKFSAA
DNVLVGAEALLRWNHPVQGLLMPDQFITLAEKTGAIVPIGTWVLNEACRQLALWHDMGHAHWSMAVNLSALQFCHAGMVE
SVAEALARHKVEPRRLTLEITETTAMRDVETTLAIMTQLDEMGVRIAIDDFGTGYSSLLHLKRIPASELKIDRGFVRDLA
EDSEDAAIVSAIVALGRTLNLQVVAEGVETTAQRSFLAGLGCDALQGYLLGRPMPAAQFTELALADVDA

Sequences:

>Translated_709_residues
MSECRHLEVIAPFEVIAPTMFPASYDALLVLFSVIVAVLASYTALDMAGRISTASGRYARLWLAGGAVAMGLGIWSMHFL
GMLSFSLPIPLGYDPAITAVSLLIAVVASAFALRLVCLEHLPRRRLALGALVLGGAVASMHYTGMAALRMQPGIQYDPWL
FLLSILIAVGASGAALWIAFRLRRHMPRVHQLRFGAALVMGGAVAAMHYTGMAAARFPIGSVCGAAGGGLQGNTLALPIL
VITICVLAVALITSVLDMRLEMRTAVLADALGVANEELEFLALHDKLTHLPNRVLLEDRFTLAIQAAARHHGRFAVLFVD
LDGFKGVNDTYGHQVGDGLLVEIANRLRASVSSEDTIARVGGDEFVLLVHVDEPEDAGVVAGKLIDVLREPANVAGHMVH
VSGSIGIAIYPVDGQDQDALMTNADAAMYHAKASGRNASYFFERSMNHQARAQQMLIQDLRAALRNGQLQLHYQPKFSAA
DNVLVGAEALLRWNHPVQGLLMPDQFITLAEKTGAIVPIGTWVLNEACRQLALWHDMGHAHWSMAVNLSALQFCHAGMVE
SVAEALARHKVEPRRLTLEITETTAMRDVETTLAIMTQLDEMGVRIAIDDFGTGYSSLLHLKRIPASELKIDRGFVRDLA
EDSEDAAIVSAIVALGRTLNLQVVAEGVETTAQRSFLAGLGCDALQGYLLGRPMPAAQFTELALADVDA
>Mature_708_residues
SECRHLEVIAPFEVIAPTMFPASYDALLVLFSVIVAVLASYTALDMAGRISTASGRYARLWLAGGAVAMGLGIWSMHFLG
MLSFSLPIPLGYDPAITAVSLLIAVVASAFALRLVCLEHLPRRRLALGALVLGGAVASMHYTGMAALRMQPGIQYDPWLF
LLSILIAVGASGAALWIAFRLRRHMPRVHQLRFGAALVMGGAVAAMHYTGMAAARFPIGSVCGAAGGGLQGNTLALPILV
ITICVLAVALITSVLDMRLEMRTAVLADALGVANEELEFLALHDKLTHLPNRVLLEDRFTLAIQAAARHHGRFAVLFVDL
DGFKGVNDTYGHQVGDGLLVEIANRLRASVSSEDTIARVGGDEFVLLVHVDEPEDAGVVAGKLIDVLREPANVAGHMVHV
SGSIGIAIYPVDGQDQDALMTNADAAMYHAKASGRNASYFFERSMNHQARAQQMLIQDLRAALRNGQLQLHYQPKFSAAD
NVLVGAEALLRWNHPVQGLLMPDQFITLAEKTGAIVPIGTWVLNEACRQLALWHDMGHAHWSMAVNLSALQFCHAGMVES
VAEALARHKVEPRRLTLEITETTAMRDVETTLAIMTQLDEMGVRIAIDDFGTGYSSLLHLKRIPASELKIDRGFVRDLAE
DSEDAAIVSAIVALGRTLNLQVVAEGVETTAQRSFLAGLGCDALQGYLLGRPMPAAQFTELALADVDA

Specific function: Unknown

COG id: COG2200

COG function: function code T; FOG: EAL domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=451, Percent_Identity=37.9157427937916, Blast_Score=296, Evalue=4e-81,
Organism=Escherichia coli, GI87081921, Length=449, Percent_Identity=34.7438752783964, Blast_Score=254, Evalue=1e-68,
Organism=Escherichia coli, GI226510982, Length=435, Percent_Identity=33.1034482758621, Blast_Score=222, Evalue=6e-59,
Organism=Escherichia coli, GI87081980, Length=245, Percent_Identity=35.1020408163265, Blast_Score=150, Evalue=3e-37,
Organism=Escherichia coli, GI87082096, Length=431, Percent_Identity=28.7703016241299, Blast_Score=149, Evalue=8e-37,
Organism=Escherichia coli, GI1786507, Length=267, Percent_Identity=33.3333333333333, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1788849, Length=443, Percent_Identity=26.86230248307, Blast_Score=147, Evalue=3e-36,
Organism=Escherichia coli, GI1790496, Length=244, Percent_Identity=34.8360655737705, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1788502, Length=242, Percent_Identity=32.6446280991736, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI87081845, Length=271, Percent_Identity=32.4723247232472, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI87081743, Length=244, Percent_Identity=33.6065573770492, Blast_Score=140, Evalue=3e-34,
Organism=Escherichia coli, GI1788381, Length=426, Percent_Identity=26.9953051643192, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1787055, Length=240, Percent_Identity=33.3333333333333, Blast_Score=122, Evalue=7e-29,
Organism=Escherichia coli, GI1787262, Length=161, Percent_Identity=34.1614906832298, Blast_Score=86, Evalue=9e-18,
Organism=Escherichia coli, GI87082007, Length=168, Percent_Identity=33.3333333333333, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1786584, Length=178, Percent_Identity=28.6516853932584, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI87081977, Length=222, Percent_Identity=26.1261261261261, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI145693134, Length=157, Percent_Identity=35.031847133758, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1788956, Length=165, Percent_Identity=35.1515151515151, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1787816, Length=171, Percent_Identity=32.7485380116959, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1787802, Length=134, Percent_Identity=32.089552238806, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI87081881, Length=167, Percent_Identity=33.5329341317365, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI1788085, Length=163, Percent_Identity=30.0613496932515, Blast_Score=73, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 76210; Mature: 76079

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS50924 MHYT ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSECRHLEVIAPFEVIAPTMFPASYDALLVLFSVIVAVLASYTALDMAGRISTASGRYAR
CCCCCEEEEECCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEE
LWLAGGAVAMGLGIWSMHFLGMLSFSLPIPLGYDPAITAVSLLIAVVASAFALRLVCLEH
EEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LPRRRLALGALVLGGAVASMHYTGMAALRMQPGIQYDPWLFLLSILIAVGASGAALWIAF
CCHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHH
RLRRHMPRVHQLRFGAALVMGGAVAAMHYTGMAAARFPIGSVCGAAGGGLQGNTLALPIL
HHHHHCCHHHHHHHHHHHHHCCHHHHHHHHCCHHHCCCCHHHHCCCCCCCCCCCHHHHHH
VITICVLAVALITSVLDMRLEMRTAVLADALGVANEELEFLALHDKLTHLPNRVLLEDRF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHEEHHHHHHHCCCCEEECCCH
TLAIQAAARHHGRFAVLFVDLDGFKGVNDTYGHQVGDGLLVEIANRLRASVSSEDTIARV
HEEEEHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEE
GGDEFVLLVHVDEPEDAGVVAGKLIDVLREPANVAGHMVHVSGSIGIAIYPVDGQDQDAL
CCCEEEEEEEECCCCCCCHHHHHHHHHHHCCHHHCCEEEEEECCCEEEEEECCCCCCCCC
MTNADAAMYHAKASGRNASYFFERSMNHQARAQQMLIQDLRAALRNGQLQLHYQPKFSAA
EECCCHHHEEECCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCC
DNVLVGAEALLRWNHPVQGLLMPDQFITLAEKTGAIVPIGTWVLNEACRQLALWHDMGHA
CCEEECHHHHHHCCCCCCCEECCHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHCCCC
HWSMAVNLSALQFCHAGMVESVAEALARHKVEPRRLTLEITETTAMRDVETTLAIMTQLD
HHEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHH
EMGVRIAIDDFGTGYSSLLHLKRIPASELKIDRGFVRDLAEDSEDAAIVSAIVALGRTLN
HCCCEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCE
LQVVAEGVETTAQRSFLAGLGCDALQGYLLGRPMPAAQFTELALADVDA
EEEEECHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
SECRHLEVIAPFEVIAPTMFPASYDALLVLFSVIVAVLASYTALDMAGRISTASGRYAR
CCCCEEEEECCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEE
LWLAGGAVAMGLGIWSMHFLGMLSFSLPIPLGYDPAITAVSLLIAVVASAFALRLVCLEH
EEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LPRRRLALGALVLGGAVASMHYTGMAALRMQPGIQYDPWLFLLSILIAVGASGAALWIAF
CCHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHH
RLRRHMPRVHQLRFGAALVMGGAVAAMHYTGMAAARFPIGSVCGAAGGGLQGNTLALPIL
HHHHHCCHHHHHHHHHHHHHCCHHHHHHHHCCHHHCCCCHHHHCCCCCCCCCCCHHHHHH
VITICVLAVALITSVLDMRLEMRTAVLADALGVANEELEFLALHDKLTHLPNRVLLEDRF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHEEHHHHHHHCCCCEEECCCH
TLAIQAAARHHGRFAVLFVDLDGFKGVNDTYGHQVGDGLLVEIANRLRASVSSEDTIARV
HEEEEHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEE
GGDEFVLLVHVDEPEDAGVVAGKLIDVLREPANVAGHMVHVSGSIGIAIYPVDGQDQDAL
CCCEEEEEEEECCCCCCCHHHHHHHHHHHCCHHHCCEEEEEECCCEEEEEECCCCCCCCC
MTNADAAMYHAKASGRNASYFFERSMNHQARAQQMLIQDLRAALRNGQLQLHYQPKFSAA
EECCCHHHEEECCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCC
DNVLVGAEALLRWNHPVQGLLMPDQFITLAEKTGAIVPIGTWVLNEACRQLALWHDMGHA
CCEEECHHHHHHCCCCCCCEECCHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHCCCC
HWSMAVNLSALQFCHAGMVESVAEALARHKVEPRRLTLEITETTAMRDVETTLAIMTQLD
HHEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHH
EMGVRIAIDDFGTGYSSLLHLKRIPASELKIDRGFVRDLAEDSEDAAIVSAIVALGRTLN
HCCCEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCE
LQVVAEGVETTAQRSFLAGLGCDALQGYLLGRPMPAAQFTELALADVDA
EEEEECHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]