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The map label for this gene is sucC1 [H]

Identifier: 94313284

GI number: 94313284

Start: 954122

End: 955333

Strand: Reverse

Name: sucC1 [H]

Synonym: Rmet_4359

Alternate gene names: 94313284

Gene position: 955333-954122 (Counterclockwise)

Preceding gene: 94313289

Following gene: 94313283

Centisome position: 37.03

GC content: 64.44

Gene sequence:

>1212_bases
GTGAACATTCACGAATATCAGGCCAAGGAGCTGCTGCGGCGCTACGACGTCGCCGTGCCAAACGGCTGCGTGGCATTTAC
CCCCGAAGAGGCTGCGCAGGCCGCACGCAAGCTGGGCGGGCCCATCTGGGTGGTGAAGTCGCAGATCCACGCCGGTGGAC
GCGGCGCGGGCCGGTTTGCCGGCGATCCATCCGGCAAGGGCGGCGTGCGCGTGGTGAAGTCCATCGACGAGGTGCAGGCA
AACGCCTCGCAGATGCTGGGCGCCACGCTGGTGACCAAGCAGACCGGGCCGGCCGGGCGCGAAGTGCGACGGCTATATAT
CGAGGAAGGCTGCGACATCGCGCGCGAGCTCTATCTTGGGATGCTGATCGACCGCGCCACATCGCGCATCACCGTCATGG
CATCCACGGAAGGCGGCATGGAAATCGAGGAGGTTGCCGCGCATACCCCGGAGAAGATCCTGAAAGTGGCGATCGATCCC
GCCAGTGGTATCCAGCCGTTCCATGCCCGGCGCCTGGCATTCGGGCTGGGTCTGTCCGGCAAGCAGGTGGCGGCGGCCAC
GCGCTTCATCCTGTCTGCCTATCGCGCATTTACGGAACTCGATGCCTCGATTGTCGAGATCAATCCGCTCGTGGTGACAG
GCAGCGGCGACGTGATCGCGCTCGACGCCAAGTTCAACTTCGACGACAACGCCCTTTTCCGGCATCCCGATATCGAAGCG
ATGCGCGACGAAAGCGAGGAAGATCCGGCCGAAACCGAAGCCGCCAGGCACGCGCTGAACTACGTGCGGCTCGACGGCAA
CATCGGCTGCATGGTCAATGGCGCGGGGCTGGCGATGGCCACGATGGACATCATCAAGCTTTACGGCGGCGAGCCGGCCA
ACTTCCTCGACGTAGGCGGTGGCGCCACCAAGGAACGCGTGACGGCGGCGTTCCGGCTCATCCTGGCCGATCCCAAGGTG
GAAGGCATCCTGGTCAACATCTTCGGCGGCATCATGCGCTGCGATGTCATTGCCGAAGGCGTGATCGCCGCCGCGCGCGA
TGTCGACCTGACAGTGCCGCTGGTGGTGCGCCTGGAAGGCACCAATGTCGAACTAGGCAAGACCATCCTGCGCGATTCGG
GACTGCCGATCCTATCGGCCAATCATCTCGCCGACGCGGCGGAGAAAGTCGTGGCCGCGGTCCGGGCCCATCAGAAGAAA
GGAGGCAAGTGA

Upstream 100 bases:

>100_bases
ATTTTCTTTTTGATATATCACATACCATATTTTACGCCGTGTGAAACCGGACAGGCGGACCCCGACCTGCGGCCACGGTG
ACAGACAAGCGAGGAGACAC

Downstream 100 bases:

>100_bases
AATGGCCGTGCTAATCGACCAACATACGCGCGTGATCTGCCAGGGTTTCACGGGCGCCCAAGGCACCTTCCACTCGGAGC
AGGCATTGGCCTATGGCACG

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MNIHEYQAKELLRRYDVAVPNGCVAFTPEEAAQAARKLGGPIWVVKSQIHAGGRGAGRFAGDPSGKGGVRVVKSIDEVQA
NASQMLGATLVTKQTGPAGREVRRLYIEEGCDIARELYLGMLIDRATSRITVMASTEGGMEIEEVAAHTPEKILKVAIDP
ASGIQPFHARRLAFGLGLSGKQVAAATRFILSAYRAFTELDASIVEINPLVVTGSGDVIALDAKFNFDDNALFRHPDIEA
MRDESEEDPAETEAARHALNYVRLDGNIGCMVNGAGLAMATMDIIKLYGGEPANFLDVGGGATKERVTAAFRLILADPKV
EGILVNIFGGIMRCDVIAEGVIAAARDVDLTVPLVVRLEGTNVELGKTILRDSGLPILSANHLADAAEKVVAAVRAHQKK
GGK

Sequences:

>Translated_403_residues
MNIHEYQAKELLRRYDVAVPNGCVAFTPEEAAQAARKLGGPIWVVKSQIHAGGRGAGRFAGDPSGKGGVRVVKSIDEVQA
NASQMLGATLVTKQTGPAGREVRRLYIEEGCDIARELYLGMLIDRATSRITVMASTEGGMEIEEVAAHTPEKILKVAIDP
ASGIQPFHARRLAFGLGLSGKQVAAATRFILSAYRAFTELDASIVEINPLVVTGSGDVIALDAKFNFDDNALFRHPDIEA
MRDESEEDPAETEAARHALNYVRLDGNIGCMVNGAGLAMATMDIIKLYGGEPANFLDVGGGATKERVTAAFRLILADPKV
EGILVNIFGGIMRCDVIAEGVIAAARDVDLTVPLVVRLEGTNVELGKTILRDSGLPILSANHLADAAEKVVAAVRAHQKK
GGK
>Mature_403_residues
MNIHEYQAKELLRRYDVAVPNGCVAFTPEEAAQAARKLGGPIWVVKSQIHAGGRGAGRFAGDPSGKGGVRVVKSIDEVQA
NASQMLGATLVTKQTGPAGREVRRLYIEEGCDIARELYLGMLIDRATSRITVMASTEGGMEIEEVAAHTPEKILKVAIDP
ASGIQPFHARRLAFGLGLSGKQVAAATRFILSAYRAFTELDASIVEINPLVVTGSGDVIALDAKFNFDDNALFRHPDIEA
MRDESEEDPAETEAARHALNYVRLDGNIGCMVNGAGLAMATMDIIKLYGGEPANFLDVGGGATKERVTAAFRLILADPKV
EGILVNIFGGIMRCDVIAEGVIAAARDVDLTVPLVVRLEGTNVELGKTILRDSGLPILSANHLADAAEKVVAAVRAHQKK
GGK

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=391, Percent_Identity=48.3375959079284, Blast_Score=364, Evalue=1e-101,
Organism=Homo sapiens, GI157779135, Length=385, Percent_Identity=50.6493506493506, Blast_Score=362, Evalue=1e-100,
Organism=Homo sapiens, GI294862256, Length=364, Percent_Identity=50.2747252747253, Blast_Score=340, Evalue=1e-93,
Organism=Escherichia coli, GI1786948, Length=394, Percent_Identity=57.3604060913706, Blast_Score=436, Evalue=1e-123,
Organism=Caenorhabditis elegans, GI17539378, Length=394, Percent_Identity=47.9695431472081, Blast_Score=363, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI17567829, Length=391, Percent_Identity=49.3606138107417, Blast_Score=357, Evalue=5e-99,
Organism=Saccharomyces cerevisiae, GI6321683, Length=394, Percent_Identity=48.4771573604061, Blast_Score=371, Evalue=1e-103,
Organism=Drosophila melanogaster, GI21356231, Length=396, Percent_Identity=49.7474747474747, Blast_Score=366, Evalue=1e-101,
Organism=Drosophila melanogaster, GI161078106, Length=391, Percent_Identity=49.1048593350384, Blast_Score=357, Evalue=1e-98,
Organism=Drosophila melanogaster, GI24645208, Length=391, Percent_Identity=49.1048593350384, Blast_Score=357, Evalue=1e-98,
Organism=Drosophila melanogaster, GI281361397, Length=392, Percent_Identity=49.4897959183673, Blast_Score=356, Evalue=2e-98,
Organism=Drosophila melanogaster, GI281361395, Length=392, Percent_Identity=49.4897959183673, Blast_Score=356, Evalue=2e-98,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 42845; Mature: 42845

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIHEYQAKELLRRYDVAVPNGCVAFTPEEAAQAARKLGGPIWVVKSQIHAGGRGAGRFA
CCCHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCC
GDPSGKGGVRVVKSIDEVQANASQMLGATLVTKQTGPAGREVRRLYIEEGCDIARELYLG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHCHHHHHHHHHH
MLIDRATSRITVMASTEGGMEIEEVAAHTPEKILKVAIDPASGIQPFHARRLAFGLGLSG
HHHHCCCCEEEEEEECCCCCCHHHHHHCCHHHHHEEEECCCCCCCHHHHHHHHHHCCCCC
KQVAAATRFILSAYRAFTELDASIVEINPLVVTGSGDVIALDAKFNFDDNALFRHPDIEA
CHHHHHHHHHHHHHHHHHHCCCEEEEECEEEEECCCCEEEEEEEECCCCCCEEECCCHHH
MRDESEEDPAETEAARHALNYVRLDGNIGCMVNGAGLAMATMDIIKLYGGEPANFLDVGG
HHCCCCCCCHHHHHHHHHHHEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECCC
GATKERVTAAFRLILADPKVEGILVNIFGGIMRCDVIAEGVIAAARDVDLTVPLVVRLEG
CCCHHHHHHHHHHEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEC
TNVELGKTILRDSGLPILSANHLADAAEKVVAAVRAHQKKGGK
CCCHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNIHEYQAKELLRRYDVAVPNGCVAFTPEEAAQAARKLGGPIWVVKSQIHAGGRGAGRFA
CCCHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCC
GDPSGKGGVRVVKSIDEVQANASQMLGATLVTKQTGPAGREVRRLYIEEGCDIARELYLG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHCHHHHHHHHHH
MLIDRATSRITVMASTEGGMEIEEVAAHTPEKILKVAIDPASGIQPFHARRLAFGLGLSG
HHHHCCCCEEEEEEECCCCCCHHHHHHCCHHHHHEEEECCCCCCCHHHHHHHHHHCCCCC
KQVAAATRFILSAYRAFTELDASIVEINPLVVTGSGDVIALDAKFNFDDNALFRHPDIEA
CHHHHHHHHHHHHHHHHHHCCCEEEEECEEEEECCCCEEEEEEEECCCCCCEEECCCHHH
MRDESEEDPAETEAARHALNYVRLDGNIGCMVNGAGLAMATMDIIKLYGGEPANFLDVGG
HHCCCCCCCHHHHHHHHHHHEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECCC
GATKERVTAAFRLILADPKVEGILVNIFGGIMRCDVIAEGVIAAARDVDLTVPLVVRLEG
CCCHHHHHHHHHHEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEC
TNVELGKTILRDSGLPILSANHLADAAEKVVAAVRAHQKKGGK
CCCHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA