Click here to switch to the map view.

The map label for this gene is sucD1 [H]

Identifier: 94313283

GI number: 94313283

Start: 953248

End: 954120

Strand: Reverse

Name: sucD1 [H]

Synonym: Rmet_4358

Alternate gene names: 94313283

Gene position: 954120-953248 (Counterclockwise)

Preceding gene: 94313284

Following gene: 94313280

Centisome position: 36.98

GC content: 66.32

Gene sequence:

>873_bases
ATGGCCGTGCTAATCGACCAACATACGCGCGTGATCTGCCAGGGTTTCACGGGCGCCCAAGGCACCTTCCACTCGGAGCA
GGCATTGGCCTATGGCACGAAAATGGTTGGCGGTGTCACGCCCGGCAAGGGCGGAGAGACGCATCTGGGGCTGCCGGTAT
TCGATACCGTATCGGCCGCCGCCCATGCCACCGGCGCCGATGCGTCGGTCATCTACGTCCCGCCGCCGTTCGCCGCCGAT
GCGATCCTCGAGGCCGTGGATGCCGGCATCGGACTGATCGTCTGCATCACCGAAGGCATTCCCGTCATTGACATGGTGCG
CGTCAAGCGGGCGCTGAGCGGCTCCGCCAGCCGGCTGGTCGGGCCCAACTGCCCGGGCGTCATCACGCCTGGCCAGTGCA
AGATCGGCATCATGCCGGGGCACATCCACAAGCCGGGACGGATCGGCGTGGTATCGCGCTCCGGCACGCTGACCTACGAA
GCGGTGGCGCAAACGACGGCAACGGGGCTTGGACAATCGACCTGCATCGGCATTGGCGGAGATCCCGTCAACGGCACGAA
CTTCATCGACAGCCTGGAACTGTTCCTTGCCGATGATCAGACCGAAGGCATCATCATGATCGGCGAGATCGGCGGGTCGG
CCGAAGAGGAAGCCGCGCAATTCCTGCGCGACGCGCGCACTCGCAAACCCGTGGTCGGATTCATCGCCGGCTCCACGGCC
CCACCGGGCCGCCGCATGGGCCATGCTGGCGCCATCATATCGGGCGGCACGGGCACGGCCGAGGCCAAGATCGAAGCGAT
GCGCGAGGCGGGTATCCACGTGGCCGCGTCTCCAGCGGAGCTGGGCAATACGATGGCGGCGGCGATGCGGTAG

Upstream 100 bases:

>100_bases
GATTCGGGACTGCCGATCCTATCGGCCAATCATCTCGCCGACGCGGCGGAGAAAGTCGTGGCCGCGGTCCGGGCCCATCA
GAAGAAAGGAGGCAAGTGAA

Downstream 100 bases:

>100_bases
GTTGGTCTGGCAGTTGTCCCCGCTCCCGCAGTGCGGGAGCGGGGACAGGGGAGAGAGGCAGCGGCTCAATCACCGATAAG
TCGCGATTTGAACCTCCGCA

Product: succinyl-CoA synthetase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha [H]

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MAVLIDQHTRVICQGFTGAQGTFHSEQALAYGTKMVGGVTPGKGGETHLGLPVFDTVSAAAHATGADASVIYVPPPFAAD
AILEAVDAGIGLIVCITEGIPVIDMVRVKRALSGSASRLVGPNCPGVITPGQCKIGIMPGHIHKPGRIGVVSRSGTLTYE
AVAQTTATGLGQSTCIGIGGDPVNGTNFIDSLELFLADDQTEGIIMIGEIGGSAEEEAAQFLRDARTRKPVVGFIAGSTA
PPGRRMGHAGAIISGGTGTAEAKIEAMREAGIHVAASPAELGNTMAAAMR

Sequences:

>Translated_290_residues
MAVLIDQHTRVICQGFTGAQGTFHSEQALAYGTKMVGGVTPGKGGETHLGLPVFDTVSAAAHATGADASVIYVPPPFAAD
AILEAVDAGIGLIVCITEGIPVIDMVRVKRALSGSASRLVGPNCPGVITPGQCKIGIMPGHIHKPGRIGVVSRSGTLTYE
AVAQTTATGLGQSTCIGIGGDPVNGTNFIDSLELFLADDQTEGIIMIGEIGGSAEEEAAQFLRDARTRKPVVGFIAGSTA
PPGRRMGHAGAIISGGTGTAEAKIEAMREAGIHVAASPAELGNTMAAAMR
>Mature_289_residues
AVLIDQHTRVICQGFTGAQGTFHSEQALAYGTKMVGGVTPGKGGETHLGLPVFDTVSAAAHATGADASVIYVPPPFAADA
ILEAVDAGIGLIVCITEGIPVIDMVRVKRALSGSASRLVGPNCPGVITPGQCKIGIMPGHIHKPGRIGVVSRSGTLTYEA
VAQTTATGLGQSTCIGIGGDPVNGTNFIDSLELFLADDQTEGIIMIGEIGGSAEEEAAQFLRDARTRKPVVGFIAGSTAP
PGRRMGHAGAIISGGTGTAEAKIEAMREAGIHVAASPAELGNTMAAAMR

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=287, Percent_Identity=70.383275261324, Blast_Score=352, Evalue=2e-97,
Organism=Homo sapiens, GI38569421, Length=308, Percent_Identity=27.9220779220779, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI38569423, Length=308, Percent_Identity=27.9220779220779, Blast_Score=98, Evalue=1e-20,
Organism=Escherichia coli, GI1786949, Length=290, Percent_Identity=68.2758620689655, Blast_Score=410, Evalue=1e-116,
Organism=Caenorhabditis elegans, GI17553126, Length=291, Percent_Identity=68.0412371134021, Blast_Score=366, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI17550194, Length=289, Percent_Identity=68.1660899653979, Blast_Score=365, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI17557344, Length=258, Percent_Identity=29.8449612403101, Blast_Score=100, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI17551266, Length=258, Percent_Identity=30.2325581395349, Blast_Score=99, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6324716, Length=291, Percent_Identity=54.9828178694158, Blast_Score=301, Evalue=7e-83,
Organism=Drosophila melanogaster, GI21356559, Length=289, Percent_Identity=61.2456747404844, Blast_Score=367, Evalue=1e-102,
Organism=Drosophila melanogaster, GI28574296, Length=290, Percent_Identity=66.8965517241379, Blast_Score=345, Evalue=2e-95,
Organism=Drosophila melanogaster, GI281363477, Length=255, Percent_Identity=30.5882352941176, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI281363475, Length=255, Percent_Identity=30.5882352941176, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI281363473, Length=255, Percent_Identity=30.5882352941176, Blast_Score=99, Evalue=3e-21,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 29363; Mature: 29232

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVLIDQHTRVICQGFTGAQGTFHSEQALAYGTKMVGGVTPGKGGETHLGLPVFDTVSAA
CEEEEECCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHH
AHATGADASVIYVPPPFAADAILEAVDAGIGLIVCITEGIPVIDMVRVKRALSGSASRLV
HHCCCCCCEEEEECCCCHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCC
GPNCPGVITPGQCKIGIMPGHIHKPGRIGVVSRSGTLTYEAVAQTTATGLGQSTCIGIGG
CCCCCCEECCCCEEEEEECCCCCCCCCEEEEECCCCEEHHHHHHHHHCCCCCCEEEECCC
DPVNGTNFIDSLELFLADDQTEGIIMIGEIGGSAEEEAAQFLRDARTRKPVVGFIAGSTA
CCCCCCHHHHEEEEEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEECCCC
PPGRRMGHAGAIISGGTGTAEAKIEAMREAGIHVAASPAELGNTMAAAMR
CCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCEEEECHHHHHHHHHHHCC
>Mature Secondary Structure 
AVLIDQHTRVICQGFTGAQGTFHSEQALAYGTKMVGGVTPGKGGETHLGLPVFDTVSAA
EEEEECCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHH
AHATGADASVIYVPPPFAADAILEAVDAGIGLIVCITEGIPVIDMVRVKRALSGSASRLV
HHCCCCCCEEEEECCCCHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCC
GPNCPGVITPGQCKIGIMPGHIHKPGRIGVVSRSGTLTYEAVAQTTATGLGQSTCIGIGG
CCCCCCEECCCCEEEEEECCCCCCCCCEEEEECCCCEEHHHHHHHHHCCCCCCEEEECCC
DPVNGTNFIDSLELFLADDQTEGIIMIGEIGGSAEEEAAQFLRDARTRKPVVGFIAGSTA
CCCCCCHHHHEEEEEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEECCCC
PPGRRMGHAGAIISGGTGTAEAKIEAMREAGIHVAASPAELGNTMAAAMR
CCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCEEEECHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]