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The map label for this gene is aaeR [H]

Identifier: 94313187

GI number: 94313187

Start: 851295

End: 852206

Strand: Reverse

Name: aaeR [H]

Synonym: Rmet_4261

Alternate gene names: 94313187

Gene position: 852206-851295 (Counterclockwise)

Preceding gene: 94313189

Following gene: 94313186

Centisome position: 33.03

GC content: 62.39

Gene sequence:

>912_bases
ATGCCCATGCAAGACCTGAACGATCTCTACTACTTCGCGCAGTCTGTGGAGCATGGTGGATTCGCCCCGGCAGGACGGGC
ATTGGGCATGCCAAAATCCAAGCTGAGCCGCCGTATCGCCATGTTGGAGGAACGCCTGGGCGTGCGGCTGATACAGCGCT
CGACCCGCCAGTTCGCCGTCACCGAAATCGGCCGCGTCTACTATGAGCACTGCAAGGCCATGCTGATGCAGGCAGAAGCC
GCGCAGGAGGCTATCGAGGTCATACAGGCCGAACCACGGGGCACCCTGCGCATGACTTGCCCGGTGGCACTCCTCCAGGT
CCATGTCGGAACGATTCTCAGCGAGTTCATGGCACGGCATCCCCTGTTGACCGTTCATTTAGAGGCCACCAACCGGCGGG
TCGATCCCGTTGCAGAGGCCATCGATTTAGCCATCCGCGTGCGCCCGCCGCCGCTCCAGGACAGCGACTTGGTCATCCGC
GTACTGGCCGAGCGCAGCCAGTGCCTTGTTGCCAGCCCCGCGCTTGCCCAAGCCCATGGCATGCCGCCTGCCCCCGCCGA
ACTTTCGGACTGGCCCAGCCTGGCCATCGGGACTCCCCAGCAGGATCACACGTGGCACCTGTACGGGCCCGACGGCGTAC
AGGCCACGATCCATCACCGTCCACGTTTGGTAACTGGTGACATGATTGCCTTGCGCAATGCGGCAGTGGCGGGGGTAGGC
GTCTGTCAGTTGCCAGTGATGATGGTGCGTGACCAGTTGACAGATGGTTCCCTCGTCCGCTTGCTACCCGACTGGGCGCC
TCGGCGCGAAATTCTTCATGCGGTTTTTCCCTCGCGGCGCGGCTTGCTGCCCGGCGTCAGATTGCTGATTGACTACCTCG
CCGAACGATTCGAAAAAATGGAAGAGGACTAG

Upstream 100 bases:

>100_bases
GGCCATTTGCTGCATTGATGCCTACAGCTTAGTATTGGGACGACGCCGGCTGTAGATATAAAAAATGATCGGCAGAGTCC
CATAAATTGAACAACCAGAC

Downstream 100 bases:

>100_bases
ACCAGAGATTCAAACGGCCGCACGGTGCATGGAGCCAGCCTGTGGCCATGGCACCGCCAGGCCGCCGCACCCTCATCGTC
CGCGCCATAGGACGCTGAGA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MPMQDLNDLYYFAQSVEHGGFAPAGRALGMPKSKLSRRIAMLEERLGVRLIQRSTRQFAVTEIGRVYYEHCKAMLMQAEA
AQEAIEVIQAEPRGTLRMTCPVALLQVHVGTILSEFMARHPLLTVHLEATNRRVDPVAEAIDLAIRVRPPPLQDSDLVIR
VLAERSQCLVASPALAQAHGMPPAPAELSDWPSLAIGTPQQDHTWHLYGPDGVQATIHHRPRLVTGDMIALRNAAVAGVG
VCQLPVMMVRDQLTDGSLVRLLPDWAPRREILHAVFPSRRGLLPGVRLLIDYLAERFEKMEED

Sequences:

>Translated_303_residues
MPMQDLNDLYYFAQSVEHGGFAPAGRALGMPKSKLSRRIAMLEERLGVRLIQRSTRQFAVTEIGRVYYEHCKAMLMQAEA
AQEAIEVIQAEPRGTLRMTCPVALLQVHVGTILSEFMARHPLLTVHLEATNRRVDPVAEAIDLAIRVRPPPLQDSDLVIR
VLAERSQCLVASPALAQAHGMPPAPAELSDWPSLAIGTPQQDHTWHLYGPDGVQATIHHRPRLVTGDMIALRNAAVAGVG
VCQLPVMMVRDQLTDGSLVRLLPDWAPRREILHAVFPSRRGLLPGVRLLIDYLAERFEKMEED
>Mature_302_residues
PMQDLNDLYYFAQSVEHGGFAPAGRALGMPKSKLSRRIAMLEERLGVRLIQRSTRQFAVTEIGRVYYEHCKAMLMQAEAA
QEAIEVIQAEPRGTLRMTCPVALLQVHVGTILSEFMARHPLLTVHLEATNRRVDPVAEAIDLAIRVRPPPLQDSDLVIRV
LAERSQCLVASPALAQAHGMPPAPAELSDWPSLAIGTPQQDHTWHLYGPDGVQATIHHRPRLVTGDMIALRNAAVAGVGV
CQLPVMMVRDQLTDGSLVRLLPDWAPRREILHAVFPSRRGLLPGVRLLIDYLAERFEKMEED

Specific function: Activates transcription of the aaeXAB operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=297, Percent_Identity=30.6397306397306, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1786401, Length=289, Percent_Identity=28.719723183391, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI87081978, Length=295, Percent_Identity=28.8135593220339, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI145693193, Length=300, Percent_Identity=28.6666666666667, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1789440, Length=294, Percent_Identity=28.9115646258503, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1787128, Length=291, Percent_Identity=23.3676975945017, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1787589, Length=300, Percent_Identity=27, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI157672245, Length=120, Percent_Identity=33.3333333333333, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788706, Length=264, Percent_Identity=26.5151515151515, Blast_Score=71, Evalue=7e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33709; Mature: 33578

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMQDLNDLYYFAQSVEHGGFAPAGRALGMPKSKLSRRIAMLEERLGVRLIQRSTRQFAV
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TEIGRVYYEHCKAMLMQAEAAQEAIEVIQAEPRGTLRMTCPVALLQVHVGTILSEFMARH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHC
PLLTVHLEATNRRVDPVAEAIDLAIRVRPPPLQDSDLVIRVLAERSQCLVASPALAQAHG
CEEEEEEECCCCCCHHHHHHHHEEEEECCCCCCCCHHHHHHHHHCCCEEEECCHHHHHCC
MPPAPAELSDWPSLAIGTPQQDHTWHLYGPDGVQATIHHRPRLVTGDMIALRNAAVAGVG
CCCCCCCCCCCCCEEECCCCCCCEEEEECCCCCEEEECCCCEEECCCHHHHHHHHHHCCH
VCQLPVMMVRDQLTDGSLVRLLPDWAPRREILHAVFPSRRGLLPGVRLLIDYLAERFEKM
HHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
EED
CCC
>Mature Secondary Structure 
PMQDLNDLYYFAQSVEHGGFAPAGRALGMPKSKLSRRIAMLEERLGVRLIQRSTRQFAV
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TEIGRVYYEHCKAMLMQAEAAQEAIEVIQAEPRGTLRMTCPVALLQVHVGTILSEFMARH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHC
PLLTVHLEATNRRVDPVAEAIDLAIRVRPPPLQDSDLVIRVLAERSQCLVASPALAQAHG
CEEEEEEECCCCCCHHHHHHHHEEEEECCCCCCCCHHHHHHHHHCCCEEEECCHHHHHCC
MPPAPAELSDWPSLAIGTPQQDHTWHLYGPDGVQATIHHRPRLVTGDMIALRNAAVAGVG
CCCCCCCCCCCCCEEECCCCCCCEEEEECCCCCEEEECCCCEEECCCHHHHHHHHHHCCH
VCQLPVMMVRDQLTDGSLVRLLPDWAPRREILHAVFPSRRGLLPGVRLLIDYLAERFEKM
HHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
EED
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]