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The map label for this gene is aceE [H]

Identifier: 94313189

GI number: 94313189

Start: 853353

End: 856031

Strand: Reverse

Name: aceE [H]

Synonym: Rmet_4263

Alternate gene names: 94313189

Gene position: 856031-853353 (Counterclockwise)

Preceding gene: 291481524

Following gene: 94313187

Centisome position: 33.18

GC content: 62.49

Gene sequence:

>2679_bases
ATGGCGCCAGTGATGCCCATCTCGTCCGCCAGCGACAACGACATCGATACTCAGGAAACCCGTGAATGGCTGGACGCGCT
GGAAGGTGTCATCGCCCACGAAGGCCCCGAGCGAGCGCATTTCCTTATTGAACAGTTGATCCGGCGCGCGCATGACGCCG
GCATCTACCTGCCGTTCAGCGCCAATACGGCCTACGTGAATACGATCCCGCTCGACAATCAGGCGCACAGTACCGGCGAC
CAGGGACTGGAGCACCGTATTCGTTCATTTATCCGATGGAATGCCATCGCGATGGTTTTGCGCGCGGGACGCGATACGAA
CGTCGGTGGACATATCGCCAGTTTTGCCTCAGCGGCGACGTTATATGAAGTCGGCTTCAACCACTTCTGGCACGCTCCGT
CCGCACAGCACGGCGGCGATCTGGTGTTTTTCCAGGGCCACTCAGCACCCGGCTTCTATGCCCGCGCCTTCCTGGAGGGA
AGGCTCAGCGAGGCCCAGATGGACAAGTTTCGCCAGGAAGTCGGCGGTCAAGGTATCTCTTCCTATCCGCATCCCTGGCT
GATGCCGGACTTCTGGCAGTTCCCGACCGTGTCGATGGGCCTGGGCCCGATCATGGGCATCTATCAGGCCCGCTTCATGA
AATACCTGCAGGACCGCGGCTTCGGCGACCATCGCGCACGCAAGGTCTGGGTATTCTGCGGCGACGGCGAAATGGACGAG
CCCGAATCCCGCGGCGCGCTGGGCATGGCCGGGCGCGAACAACTCGACAACCTGGTGTTCGTCATCAACTGCAACCTCCA
ACGCCTGGACGGCCCCGTGCGTGGCAATGGCAAGATCATTCAGGAACTGGAATCCGAGTTCCGCGGCGCCGGCTGGAATG
TGATCAAAGTCGTATGGGGCAGTAAGTGGGACGCCCTGCTGGCCCGCGACAAGGACGGCATCCTGGCGCAACGGATGATG
GCCTGCGTCGACGGTGACTACCAGACCTTCAAGTCCAAAGACGGCGCCTACGTGCGCGAACATTTCTTCAACTCCCCAGC
CCTCAAGGCGCTGGTGGCGGATTGGTCCGACGACGACATCTGGCAACTCAATCGCGGCGGCCATGATCCACACAAGGTCT
ACGCCGCATACCACGCAGCGGCGCACCACACCGGCCAGCCCACCGTGATCCTGGCCAAGACTATCAAGGGCTATGGCATG
GGCGAGGCGGGCGAGGCCCAGAACATCACCCACCAGCAAAAGCATATGCGCGTGGAAACACTGGGGCAGTTCCGCGACCG
CTTCGGCCTGCCACTCACCGACGAGCAACTCGCCGATCTCAGCTACCTGAAATTCGAGGAAGGATCGCCCGAACACGCCT
ATCTGCATCAGCGCAGACAGGCCCTTGGGGGCTACCTCCCATCGCGCCGCCGCACGGGGCCTGAACTGCCGGTGCCGCCA
TTGTCCGCATTTGATGGGCAACTTAAGGCGAGCGGCGAAGGACGCGAGTTCTCCACCGCCATGAGCTTCGTGCGCATCCT
CAATACGTTGCTACGTGACAAGGCGCTCGGCAAGCGCATCGTGCCGATTGTCTCGGACGAGTCGCGCACGTTCGGGATGG
AGGGCCTCTTCCGCCAGATCGGTATCTGGTCGCAGCAGGGCCAGACCTATACGCCGCAGGACGCGTCGCAATTGAGTTTC
TACAAGGAATCCAAGGACGGCCAGATCCTCCAGGAAGGGATTAACGAAGCCGGCGCCATGGCAGACTGGATTGCCGCGGC
CACGTCGTACAGCACGCATGGCGAGCCAATGATCCCCTTCTTCATCTTCTATTCGATCTTCGGTTTCCAGCGCTTTGGCG
ATCTGGCCTGGGCCGCCGGCGACCAGCGCGCGCGCGGCTTCCTACTGGGCGGCACAGCGGGGCGCACCACGCTCAACGGC
GAAGGCCTGCAGCATGAAGACGGCCACAGCCTGGTCTGGGGTGGCACCATCCCCAACTGCGTCTGCTACGACCCCACGTT
TGCCTTCGAACTCGCGGTCATCATCCAGGACGGCCTGCGCCGCATGCTGCAGATGCAGGAAGACGTCTACTACTACATCA
CCGTGATGAACGAGAACTACGAGCATCCGGCGATGCCCGAGGGCGCGGAGCAAGACATTCTCAAGGGCATGTACGCATTC
CGCCGCACAAGCAACGGCGAAGCCCCCCGCGTGCAGTTGCTGGGCGCCGGCACGATCTTCCGCGAAGTCATTGCGGCGTC
AGCCATGCTGGAGCAGCACTGGGGCGTGCAGGCCGACCTGTGGGGTTGTCCCAGCTTCACCGAACTGGCACGCCAGGGCA
ACGAAGTCATACGCTGGAACCTGCTGCACCCTGACGAGGCGCCGCGCACATCGCATGTGGAACACTGCCTGGCCGACACG
CGTGGCCCGGTTATCGCCGCCACCGACTATGTGCGGGCGTTGGCCGAACAGATCCGTCCGTTCGTGCCGCGTGCGTACAC
AGTGCTGGGCACTGACGGCTATGGCCGTTCGGATACTCGCGAACAACTTCGTGATTTCTTCGAGGTGGACCGCCGCTGGA
TCACACTGGCGGCCCTGAAGGCACTGGTGGATGAAGGCACGCTGGAGCGCGGCGTACTGAGCCAGGCCATCGCCAAGTAC
GGCATCGATCCGGAGAAGCCCTACCCTTTGCGCGCCTGA

Upstream 100 bases:

>100_bases
CCATACTGCTTCGCGGTGCTAGTCTTTTCCCCCTTGCATATTCCCTTCACTGCGGCCGGTTCCGTGCCGCTTGCCCGCAC
CGGGCCGACAGGAGATCACC

Downstream 100 bases:

>100_bases
GCCCAATTTCAACGTTTGGGCGCCTCCGCATACAGGGGTACCACTTCGGCGCTTTCCATCGACGAGCCGGGAACTTCCCA
CGGCGGCTGCGAAAGCGAAG

Product: 2-oxoacid dehydrogenase subunit E1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 892; Mature: 891

Protein sequence:

>892_residues
MAPVMPISSASDNDIDTQETREWLDALEGVIAHEGPERAHFLIEQLIRRAHDAGIYLPFSANTAYVNTIPLDNQAHSTGD
QGLEHRIRSFIRWNAIAMVLRAGRDTNVGGHIASFASAATLYEVGFNHFWHAPSAQHGGDLVFFQGHSAPGFYARAFLEG
RLSEAQMDKFRQEVGGQGISSYPHPWLMPDFWQFPTVSMGLGPIMGIYQARFMKYLQDRGFGDHRARKVWVFCGDGEMDE
PESRGALGMAGREQLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKVVWGSKWDALLARDKDGILAQRMM
ACVDGDYQTFKSKDGAYVREHFFNSPALKALVADWSDDDIWQLNRGGHDPHKVYAAYHAAAHHTGQPTVILAKTIKGYGM
GEAGEAQNITHQQKHMRVETLGQFRDRFGLPLTDEQLADLSYLKFEEGSPEHAYLHQRRQALGGYLPSRRRTGPELPVPP
LSAFDGQLKASGEGREFSTAMSFVRILNTLLRDKALGKRIVPIVSDESRTFGMEGLFRQIGIWSQQGQTYTPQDASQLSF
YKESKDGQILQEGINEAGAMADWIAAATSYSTHGEPMIPFFIFYSIFGFQRFGDLAWAAGDQRARGFLLGGTAGRTTLNG
EGLQHEDGHSLVWGGTIPNCVCYDPTFAFELAVIIQDGLRRMLQMQEDVYYYITVMNENYEHPAMPEGAEQDILKGMYAF
RRTSNGEAPRVQLLGAGTIFREVIAASAMLEQHWGVQADLWGCPSFTELARQGNEVIRWNLLHPDEAPRTSHVEHCLADT
RGPVIAATDYVRALAEQIRPFVPRAYTVLGTDGYGRSDTREQLRDFFEVDRRWITLAALKALVDEGTLERGVLSQAIAKY
GIDPEKPYPLRA

Sequences:

>Translated_892_residues
MAPVMPISSASDNDIDTQETREWLDALEGVIAHEGPERAHFLIEQLIRRAHDAGIYLPFSANTAYVNTIPLDNQAHSTGD
QGLEHRIRSFIRWNAIAMVLRAGRDTNVGGHIASFASAATLYEVGFNHFWHAPSAQHGGDLVFFQGHSAPGFYARAFLEG
RLSEAQMDKFRQEVGGQGISSYPHPWLMPDFWQFPTVSMGLGPIMGIYQARFMKYLQDRGFGDHRARKVWVFCGDGEMDE
PESRGALGMAGREQLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKVVWGSKWDALLARDKDGILAQRMM
ACVDGDYQTFKSKDGAYVREHFFNSPALKALVADWSDDDIWQLNRGGHDPHKVYAAYHAAAHHTGQPTVILAKTIKGYGM
GEAGEAQNITHQQKHMRVETLGQFRDRFGLPLTDEQLADLSYLKFEEGSPEHAYLHQRRQALGGYLPSRRRTGPELPVPP
LSAFDGQLKASGEGREFSTAMSFVRILNTLLRDKALGKRIVPIVSDESRTFGMEGLFRQIGIWSQQGQTYTPQDASQLSF
YKESKDGQILQEGINEAGAMADWIAAATSYSTHGEPMIPFFIFYSIFGFQRFGDLAWAAGDQRARGFLLGGTAGRTTLNG
EGLQHEDGHSLVWGGTIPNCVCYDPTFAFELAVIIQDGLRRMLQMQEDVYYYITVMNENYEHPAMPEGAEQDILKGMYAF
RRTSNGEAPRVQLLGAGTIFREVIAASAMLEQHWGVQADLWGCPSFTELARQGNEVIRWNLLHPDEAPRTSHVEHCLADT
RGPVIAATDYVRALAEQIRPFVPRAYTVLGTDGYGRSDTREQLRDFFEVDRRWITLAALKALVDEGTLERGVLSQAIAKY
GIDPEKPYPLRA
>Mature_891_residues
APVMPISSASDNDIDTQETREWLDALEGVIAHEGPERAHFLIEQLIRRAHDAGIYLPFSANTAYVNTIPLDNQAHSTGDQ
GLEHRIRSFIRWNAIAMVLRAGRDTNVGGHIASFASAATLYEVGFNHFWHAPSAQHGGDLVFFQGHSAPGFYARAFLEGR
LSEAQMDKFRQEVGGQGISSYPHPWLMPDFWQFPTVSMGLGPIMGIYQARFMKYLQDRGFGDHRARKVWVFCGDGEMDEP
ESRGALGMAGREQLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKVVWGSKWDALLARDKDGILAQRMMA
CVDGDYQTFKSKDGAYVREHFFNSPALKALVADWSDDDIWQLNRGGHDPHKVYAAYHAAAHHTGQPTVILAKTIKGYGMG
EAGEAQNITHQQKHMRVETLGQFRDRFGLPLTDEQLADLSYLKFEEGSPEHAYLHQRRQALGGYLPSRRRTGPELPVPPL
SAFDGQLKASGEGREFSTAMSFVRILNTLLRDKALGKRIVPIVSDESRTFGMEGLFRQIGIWSQQGQTYTPQDASQLSFY
KESKDGQILQEGINEAGAMADWIAAATSYSTHGEPMIPFFIFYSIFGFQRFGDLAWAAGDQRARGFLLGGTAGRTTLNGE
GLQHEDGHSLVWGGTIPNCVCYDPTFAFELAVIIQDGLRRMLQMQEDVYYYITVMNENYEHPAMPEGAEQDILKGMYAFR
RTSNGEAPRVQLLGAGTIFREVIAASAMLEQHWGVQADLWGCPSFTELARQGNEVIRWNLLHPDEAPRTSHVEHCLADTR
GPVIAATDYVRALAEQIRPFVPRAYTVLGTDGYGRSDTREQLRDFFEVDRRWITLAALKALVDEGTLERGVLSQAIAKYG
IDPEKPYPLRA

Specific function: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components:pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydroge

COG id: COG2609

COG function: function code C; Pyruvate dehydrogenase complex, dehydrogenase (E1) component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786304, Length=883, Percent_Identity=59.2298980747452, Blast_Score=1077, Evalue=0.0,

Paralogues:

None

Copy number: 1140 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 400 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004660
- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =1.2.4.1 [H]

Molecular weight: Translated: 99693; Mature: 99561

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPVMPISSASDNDIDTQETREWLDALEGVIAHEGPERAHFLIEQLIRRAHDAGIYLPFS
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEC
ANTAYVNTIPLDNQAHSTGDQGLEHRIRSFIRWNAIAMVLRAGRDTNVGGHIASFASAAT
CCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
LYEVGFNHFWHAPSAQHGGDLVFFQGHSAPGFYARAFLEGRLSEAQMDKFRQEVGGQGIS
HHHHHHHHHCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCC
SYPHPWLMPDFWQFPTVSMGLGPIMGIYQARFMKYLQDRGFGDHRARKVWVFCGDGEMDE
CCCCCCCCCCCCCCCCCHHCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCC
PESRGALGMAGREQLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKVVWG
CHHCCCCCCCCHHHHCCEEEEEECCHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEEC
SKWDALLARDKDGILAQRMMACVDGDYQTFKSKDGAYVREHFFNSPALKALVADWSDDDI
CCCHHHHHCCCCCHHHHHHHHHHCCCHHHHHCCCCCHHHHHHCCCHHHHHHHHCCCCCCC
WQLNRGGHDPHKVYAAYHAAAHHTGQPTVILAKTIKGYGMGEAGEAQNITHQQKHMRVET
EECCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHH
LGQFRDRFGLPLTDEQLADLSYLKFEEGSPEHAYLHQRRQALGGYLPSRRRTGPELPVPP
HHHHHHHCCCCCCHHHHHCCHHEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
LSAFDGQLKASGEGREFSTAMSFVRILNTLLRDKALGKRIVPIVSDESRTFGMEGLFRQI
CHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCEECEEECCCCCCCCHHHHHHHH
GIWSQQGQTYTPQDASQLSFYKESKDGQILQEGINEAGAMADWIAAATSYSTHGEPMIPF
CCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
FIFYSIFGFQRFGDLAWAAGDQRARGFLLGGTAGRTTLNGEGLQHEDGHSLVWGGTIPNC
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEECCCCCCCCCCCEEEECCCCCCC
VCYDPTFAFELAVIIQDGLRRMLQMQEDVYYYITVMNENYEHPAMPEGAEQDILKGMYAF
EEECCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHH
RRTSNGEAPRVQLLGAGTIFREVIAASAMLEQHWGVQADLWGCPSFTELARQGNEVIRWN
HHCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHCCCCEEEEE
LLHPDEAPRTSHVEHCLADTRGPVIAATDYVRALAEQIRPFVPRAYTVLGTDGYGRSDTR
EECCCCCCCHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHH
EQLRDFFEVDRRWITLAALKALVDEGTLERGVLSQAIAKYGIDPEKPYPLRA
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
APVMPISSASDNDIDTQETREWLDALEGVIAHEGPERAHFLIEQLIRRAHDAGIYLPFS
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEC
ANTAYVNTIPLDNQAHSTGDQGLEHRIRSFIRWNAIAMVLRAGRDTNVGGHIASFASAAT
CCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
LYEVGFNHFWHAPSAQHGGDLVFFQGHSAPGFYARAFLEGRLSEAQMDKFRQEVGGQGIS
HHHHHHHHHCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCC
SYPHPWLMPDFWQFPTVSMGLGPIMGIYQARFMKYLQDRGFGDHRARKVWVFCGDGEMDE
CCCCCCCCCCCCCCCCCHHCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCC
PESRGALGMAGREQLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKVVWG
CHHCCCCCCCCHHHHCCEEEEEECCHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEEC
SKWDALLARDKDGILAQRMMACVDGDYQTFKSKDGAYVREHFFNSPALKALVADWSDDDI
CCCHHHHHCCCCCHHHHHHHHHHCCCHHHHHCCCCCHHHHHHCCCHHHHHHHHCCCCCCC
WQLNRGGHDPHKVYAAYHAAAHHTGQPTVILAKTIKGYGMGEAGEAQNITHQQKHMRVET
EECCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHH
LGQFRDRFGLPLTDEQLADLSYLKFEEGSPEHAYLHQRRQALGGYLPSRRRTGPELPVPP
HHHHHHHCCCCCCHHHHHCCHHEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
LSAFDGQLKASGEGREFSTAMSFVRILNTLLRDKALGKRIVPIVSDESRTFGMEGLFRQI
CHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCEECEEECCCCCCCCHHHHHHHH
GIWSQQGQTYTPQDASQLSFYKESKDGQILQEGINEAGAMADWIAAATSYSTHGEPMIPF
CCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
FIFYSIFGFQRFGDLAWAAGDQRARGFLLGGTAGRTTLNGEGLQHEDGHSLVWGGTIPNC
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEECCCCCCCCCCCEEEECCCCCCC
VCYDPTFAFELAVIIQDGLRRMLQMQEDVYYYITVMNENYEHPAMPEGAEQDILKGMYAF
EEECCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHH
RRTSNGEAPRVQLLGAGTIFREVIAASAMLEQHWGVQADLWGCPSFTELARQGNEVIRWN
HHCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHCCCCEEEEE
LLHPDEAPRTSHVEHCLADTRGPVIAATDYVRALAEQIRPFVPRAYTVLGTDGYGRSDTR
EECCCCCCCHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHH
EQLRDFFEVDRRWITLAALKALVDEGTLERGVLSQAIAKYGIDPEKPYPLRA
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8021225 [H]