Click here to switch to the map view.

The map label for this gene is ttdR [H]

Identifier: 94313019

GI number: 94313019

Start: 661063

End: 661980

Strand: Reverse

Name: ttdR [H]

Synonym: Rmet_4092

Alternate gene names: 94313019

Gene position: 661980-661063 (Counterclockwise)

Preceding gene: 94313024

Following gene: 94313017

Centisome position: 25.66

GC content: 65.36

Gene sequence:

>918_bases
ATGGATCAGATCCCGGACCTCAATGACCTTCGGCTGTTCGCCGAAGTGGTGGATCGCGGCAGCTTCACTGCCGCCGCCCG
TAGCCTTGGCCAGCAGACATCGAAACTGAGCCGGCGCATCCGCGCGCTGGAAGAGGCGCTTGGCGTGCGCCTGCTGAACC
GCACCAGCCGCAGCCTGTCGTTGACGGAGACCGGGCGACGCTTTCACCAGCACTGCCTTGCGGTGGTGGCCGAAGCCAGG
GCCGCCAAGGAGATCGTCGACCAGACCCGCTCGCAGCCACAGGGCACCGTGCGGATCAGTTGCCCGGTTGCGCTCCTCAG
TTCGGGCGTCGCCGAGACCATCTCTCGTTACGTGCACGACAACCCACAGGTGCAGGTTCTGGTCGACGCCACCAATCGCC
GCGTCGACGTCATCGAAGAAGGGCTGGACTTCGCGATCCGCGTCAGGCCCGCGCCACTGGAGGACACCGACCTCGCGGTC
CGGCAACTGGGCTTGTCCACGTTCGTCCTCGTCGCAAGTCCGGAACTGGCAAGGCTGCACGCCCCGCCAGCCTCGATCGA
ATCGCTACAGGACTGGCCGACCATTGCCATGGCCAGCAACAACGAGCGATACGTCTGGAATCTTGTCGATGCCGGCGGAA
AGGAGCAGGCTTTCGCCCACCGCCCCCGACTCGCAACGGACGATATCGCAAGCCTGAGAATCGCCGCGATGTTCGGCGTC
GGCGTGGCCATGCTGCCGAGGGAATTCATCGAAGAGGATCTGCAGTCAGGCCGGCTGCTGCATCTGCTGCCCGAACTGGC
CTCGACGAGTGGGCTCGTGCACGCGATCTTTCCGACGCGGCGCGGCATGGTGCCCGCCGTGCGCCATCTGCTCGATGCAC
TCGTCGCCGGATTCGAAGCCGTGAATCAGGGGCGATAG

Upstream 100 bases:

>100_bases
ATGAATGCTAGACAAGCAACGACAACGGCGAAATATCCGAGTTTGCAAAGCATCGTTGCCACCAGTAGGATGATCTGATC
ATCCTGAAGCGCCTCCTCAC

Downstream 100 bases:

>100_bases
CGGGCCTGCCCCTTACCCTCACTTACCCTCAGCCCAACTCCCGCCCCATCATCCAGCGCTTGTAACGCCTTGTCTGGCAG
GCGTTGGCCATTTGCTGCAT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MDQIPDLNDLRLFAEVVDRGSFTAAARSLGQQTSKLSRRIRALEEALGVRLLNRTSRSLSLTETGRRFHQHCLAVVAEAR
AAKEIVDQTRSQPQGTVRISCPVALLSSGVAETISRYVHDNPQVQVLVDATNRRVDVIEEGLDFAIRVRPAPLEDTDLAV
RQLGLSTFVLVASPELARLHAPPASIESLQDWPTIAMASNNERYVWNLVDAGGKEQAFAHRPRLATDDIASLRIAAMFGV
GVAMLPREFIEEDLQSGRLLHLLPELASTSGLVHAIFPTRRGMVPAVRHLLDALVAGFEAVNQGR

Sequences:

>Translated_305_residues
MDQIPDLNDLRLFAEVVDRGSFTAAARSLGQQTSKLSRRIRALEEALGVRLLNRTSRSLSLTETGRRFHQHCLAVVAEAR
AAKEIVDQTRSQPQGTVRISCPVALLSSGVAETISRYVHDNPQVQVLVDATNRRVDVIEEGLDFAIRVRPAPLEDTDLAV
RQLGLSTFVLVASPELARLHAPPASIESLQDWPTIAMASNNERYVWNLVDAGGKEQAFAHRPRLATDDIASLRIAAMFGV
GVAMLPREFIEEDLQSGRLLHLLPELASTSGLVHAIFPTRRGMVPAVRHLLDALVAGFEAVNQGR
>Mature_305_residues
MDQIPDLNDLRLFAEVVDRGSFTAAARSLGQQTSKLSRRIRALEEALGVRLLNRTSRSLSLTETGRRFHQHCLAVVAEAR
AAKEIVDQTRSQPQGTVRISCPVALLSSGVAETISRYVHDNPQVQVLVDATNRRVDVIEEGLDFAIRVRPAPLEDTDLAV
RQLGLSTFVLVASPELARLHAPPASIESLQDWPTIAMASNNERYVWNLVDAGGKEQAFAHRPRLATDDIASLRIAAMFGV
GVAMLPREFIEEDLQSGRLLHLLPELASTSGLVHAIFPTRRGMVPAVRHLLDALVAGFEAVNQGR

Specific function: Positive regulator required for L-tartrate-dependent anaerobic growth on glycerol. Induces expression of the ttdA-ttdB- ygjE operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789440, Length=286, Percent_Identity=27.2727272727273, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1789639, Length=300, Percent_Identity=30, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI87081978, Length=301, Percent_Identity=28.9036544850498, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI1786401, Length=287, Percent_Identity=27.8745644599303, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI145693193, Length=289, Percent_Identity=28.3737024221453, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI1787128, Length=294, Percent_Identity=25.5102040816327, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787589, Length=296, Percent_Identity=26.3513513513513, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1787601, Length=191, Percent_Identity=30.3664921465969, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1788481, Length=299, Percent_Identity=27.4247491638796, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1786448, Length=296, Percent_Identity=23.9864864864865, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1788706, Length=267, Percent_Identity=25.8426966292135, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI87082132, Length=262, Percent_Identity=24.0458015267176, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1790208, Length=250, Percent_Identity=26, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1787879, Length=309, Percent_Identity=26.8608414239482, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787949, Length=297, Percent_Identity=25.9259259259259, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33440; Mature: 33440

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQIPDLNDLRLFAEVVDRGSFTAAARSLGQQTSKLSRRIRALEEALGVRLLNRTSRSLS
CCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
LTETGRRFHQHCLAVVAEARAAKEIVDQTRSQPQGTVRISCPVALLSSGVAETISRYVHD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHCCHHHHHHHHHCC
NPQVQVLVDATNRRVDVIEEGLDFAIRVRPAPLEDTDLAVRQLGLSTFVLVASPELARLH
CCCEEEEEECCCCHHHHHHCCCCEEEEECCCCCCHHHHHHHHHCHHEEEEEECCHHHHHC
APPASIESLQDWPTIAMASNNERYVWNLVDAGGKEQAFAHRPRLATDDIASLRIAAMFGV
CCCHHHHHHHCCCCEEEECCCCEEEEEEECCCCCCHHHHHCCCCCCCHHHHHHHHHHHHH
GVAMLPREFIEEDLQSGRLLHLLPELASTSGLVHAIFPTRRGMVPAVRHLLDALVAGFEA
HHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHH
VNQGR
HCCCC
>Mature Secondary Structure
MDQIPDLNDLRLFAEVVDRGSFTAAARSLGQQTSKLSRRIRALEEALGVRLLNRTSRSLS
CCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
LTETGRRFHQHCLAVVAEARAAKEIVDQTRSQPQGTVRISCPVALLSSGVAETISRYVHD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHCCHHHHHHHHHCC
NPQVQVLVDATNRRVDVIEEGLDFAIRVRPAPLEDTDLAVRQLGLSTFVLVASPELARLH
CCCEEEEEECCCCHHHHHHCCCCEEEEECCCCCCHHHHHHHHHCHHEEEEEECCHHHHHC
APPASIESLQDWPTIAMASNNERYVWNLVDAGGKEQAFAHRPRLATDDIASLRIAAMFGV
CCCHHHHHHHCCCCEEEECCCCEEEEEEECCCCCCHHHHHCCCCCCCHHHHHHHHHHHHH
GVAMLPREFIEEDLQSGRLLHLLPELASTSGLVHAIFPTRRGMVPAVRHLLDALVAGFEA
HHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHH
VNQGR
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]