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The map label for this gene is pyc [H]

Identifier: 94312997

GI number: 94312997

Start: 634644

End: 638024

Strand: Reverse

Name: pyc [H]

Synonym: Rmet_4069

Alternate gene names: 94312997

Gene position: 638024-634644 (Counterclockwise)

Preceding gene: 94312998

Following gene: 94312996

Centisome position: 24.73

GC content: 68.2

Gene sequence:

>3381_bases
ATGCAGCTTGACGCACGCGCCTTACATTCTGGCTTGCATCCGGGCGGTACTGCATCCATCCCTCACGGAATCGAGCCAGT
GAAAAAGCTTCTGATTGCCAACCGCGGCGAAATCGCGCTGCGGGTTCAACGCGCCGCGCAGGATCTCGGCATTGCCACTG
TCGCGGTGTACGCCACCGACGACGCTCAATCGCGCCATCGCCAGCTTGCCGATGAAGCCATCGCGCTGCCCGGCAATGGT
CCGGCTACCTATCTCGACATCGACGCCATTCTCGGCGCGGCGCGCGCCGCTGGCTGCGATGCAATCCATCCCGGCTACGG
CTTCCTGAGCGAGCGTGCCGACTTCGCGCAGGCATGCGCGGCAGCAGGTATCACGTTCGTCGGCCCCACGCCCGAGCAGC
TTGCCCTGTTCGGCGACAAGGGCCGCGCGCTCGAGCTGGCCGCGCAGTGCGATGTCCCGGTGATGCCGGCCACCCCCGGT
GGCGCTTCGCTCGACGACGTCCGCGCATTCTTCGCGGCGCAGCAAGGCAATGGCATCGTGCTGAAGGCCGTGGGCGGCGG
CGGTGGGCGCGGGATGCGCGTCGTCCGCGATGCCGAAGCGCTGGCCGAAGCCTACGCGCGCTGCCAGTCGGAGGCCCGCA
GCGCCTTCGGCATCGAAGCGATCTATGCCGAGCGACTGGTCGAACGCGCGCGCCATATTGAAGTACAGATCATCGGCGAT
GGGACTGAGACAATCGCGCTCGGCGAACGCGATTGCACGCTACAGCGGCGCTTCCAGAAACTGGTGGAAATCGCGCCGAG
CCCGGTGCTGACACCCGCCCTGCGCGACCGCATCGTGCAGGCCGCCAGCAGGATCGCAAAGCACACCGGCTACCGCAGCC
TGGGCACGTTCGAGTTCCTGGTGGAGACCGACGACGCCGGCACGCCCCACGGCTTCGTGTTCATCGAAGCCAATCCCCGT
CTGCAGGTAGAGCACACCATCACGGAACAGGTGACGGGTCTCGATCTCGTTGCCCTCCAGCTTGGCCTTGCTGATGGCCG
GAGCCTGCGCGACCTGGGTCTCGACCCCGCCGCGCCGCCCACGGCGCGCGGGTTCTCCGTTCAGCTACGCATCAATGCCG
AGGCCACCGATGCGCAGGGCCAGGCGCGCCCGGCGCTCGGAAGGCTCGAACGTTTCGATCCGCCCACCGGGCCCGATGTT
CGCGTCGACACGCACGGCTATACCGGCTACGCGCCGCCAGCTGGCTATGACTCGCTGCTGGCCAAACTGATCGTAAGCAC
TTCTTCACCCCGTTTCGAGGACGTGGTGCGGCGCGTGCGGCGTGCGCTCGGTGAATGCCGTGTTGACGGCGTGCCAAGCA
ACCTCGACCTGCTGCGCGCCCTGGTGGCACGCGAAGACTTCGCGACACAGCATGTCCATACACGTCACTTCGAGGCGATC
CTGCCGGAACTGCTGACCGCCGCGCAACGCGTGGCGGCCAGTGACGCCGCGCGACAGGCTTCCATCGGCATCGCGCAGAC
CGCCCCCGTGCCTGTACCGACCGCTACTGCCGAGGCCATCGACGAAGGACTGGTTGCAGTGCGCGCGCCAATGAACGGGC
GCGTGGTCGAGATGCGCGTCCAGGAAGACGACATCGTGCAACCGGGCCAGATCGTGGCGATCCTCGACGCGATGAAGATG
GAGCACACCATCGCGGCCGAGTGCGCGGGGCGTGTGATCGACGTGCGCGTCGGTGCCACCGGGCAGACTGTCGAAGGGCA
AATCCTGCTCGTGCTGGAGCCGGTGGCTGACGCCGGCGTCGCGCATCACCGCAGCGAGGCGGCAGACCCACGCGCGATCC
GCCCCGATCTGCAACGTGTGCGCGATCGCGATGCGTTCCTCGATGATGCCGCGCGGCCGGACGCGGTGGCGAAACGCCAT
GCGCGCGGCCAGCGCACCGCGCGCGAGAACGTGGCTGATCTGTGCGACGCAGGCAGTTTCGTCGAGTACGGCGCCTATGC
GGTAGCCGCGCAGGCCAGCCGACGCAGCGCCGAGGACCTGATCGCCAATACGCCAGCCGATGGCCTGATCACCGGCACCG
GCCGCATCAACGGCACCCGATTCGCACCGGAGCGCGCGCGCTGCGCAGTGCTGGCGTACGACGCCACGGTGCTGGCGGGC
ACGCAGGGCAAGCGCAATCACATCAAGACAGATCGCATCCTGCAGGTGGCCGCCGAACAGAAGCTGCCAACCGTGATCTT
CGCGGAAGGCGGCGGCGGACGCCCCGGCGATGTGGACTTTCCTACCGTCGCTGGCCTCTACCAACCGTCCTTCGCCGCAT
TTGCCGCGCTGAGCGGCGAGGTGCCGGTGATCGGCATCGCCGCTGGCCGGTGCTTCGCGGGCAACGCTGCCCTGCTCGGC
TGCAGCGACGTGATCATCGCCACGCGCGACGCGAACATCGGCATGGCCGGCCCCGCGATGATCGAAGGCGGCGGCCTTGG
CGTGTATCGCCCGGAGGACATCGGCCCCGCCGCCGTGCAGTACCAGAATGGCGTGGTCGACCTGCTTGTCGACGACGAAG
CCGAGGCCGTGCGCGCCGCGAAGCATTACCTGTCGATGTTCCAGGGCCGCACGCAGGACTGGGAGGCGCCCGACGCCCTG
ATGCTGCGCGGCGTGGTGCCCGAGAACCGCCTGCGCGTCTACGACACCCGTGCCGCGATCCAGGGCATTGCCGACGTCGG
CAGCGTGATCGAGTTGCGCGCGGGCTATGGCACTGGCGTGCATACCGCGCTGGCGCGTATCGAAGGCCGACCCGTGGGCA
TCGTCGCCAACAACCCGCGTCACCTGGGTGGCGCCATCGACGTGGACGGCGCGGACAAGGCCGCGCGATTCATGCAGCTG
TGCGATACGCATGGCCTGCCGATCGTCTCGCTGATCGACACGCCGGGCTTTATGGTCGGCCCGGAGATCGAAGCCCGCGC
GCAAGTCCGTCATGTGTCCCGATTGTTCGTGCTGGGCGCCAAGGTGCGCGTGCCGTTCATGGCCGTGGTGCTGCGCAAGG
GCTACGGCCTGGGTGCGATGGCCATGGCTGCAGGCGGCTTCCGCGCGCCGGCCTTCACCATCTCCTGGCCAACCGGCGAG
TTCGGCGGCATGGGACTGGAAGGGGCGGTACGTCTCGGCTTCCGCAAGGAGTTGGAAGCGCTGCCGGCTGGCCCCGAACG
CGACGCCCTCTACCAGCAGCTCGTGGCGCAGATGTACGAACGCGGACACGCAATCAATGCCGCAGCCGGGCTCGAGATCG
ACGCGGTCATCGATCCGGCCGAAACGCGGCGCTGGTTGCTGGCCGGCCTCGATGCCGCCCCACGAGACGAGGCGCCCCGA
CGTTACGTGGATGCGTGGTAG

Upstream 100 bases:

>100_bases
GGCAGAAGGCAACTCAAGGCAACTCAAGGCAGCAATTCCGCAGGGCGGCTGCGGCTATACAGCCGATGCATGGCCGCCAT
GAAACTTGCGCCATGGGTGC

Downstream 100 bases:

>100_bases
CCGATGCAGTGACTGAACTGGCCCCCTGACTCCGCTCCCGCCATGCTGGAGCGCGGAGCAAATACTCCTGGAGACACGAT
GGAAGACGCAGCTTTCTTCG

Product: acetyl-CoA carboxylase

Products: NA

Alternate protein names: Pyruvic carboxylase; PYC [H]

Number of amino acids: Translated: 1126; Mature: 1126

Protein sequence:

>1126_residues
MQLDARALHSGLHPGGTASIPHGIEPVKKLLIANRGEIALRVQRAAQDLGIATVAVYATDDAQSRHRQLADEAIALPGNG
PATYLDIDAILGAARAAGCDAIHPGYGFLSERADFAQACAAAGITFVGPTPEQLALFGDKGRALELAAQCDVPVMPATPG
GASLDDVRAFFAAQQGNGIVLKAVGGGGGRGMRVVRDAEALAEAYARCQSEARSAFGIEAIYAERLVERARHIEVQIIGD
GTETIALGERDCTLQRRFQKLVEIAPSPVLTPALRDRIVQAASRIAKHTGYRSLGTFEFLVETDDAGTPHGFVFIEANPR
LQVEHTITEQVTGLDLVALQLGLADGRSLRDLGLDPAAPPTARGFSVQLRINAEATDAQGQARPALGRLERFDPPTGPDV
RVDTHGYTGYAPPAGYDSLLAKLIVSTSSPRFEDVVRRVRRALGECRVDGVPSNLDLLRALVAREDFATQHVHTRHFEAI
LPELLTAAQRVAASDAARQASIGIAQTAPVPVPTATAEAIDEGLVAVRAPMNGRVVEMRVQEDDIVQPGQIVAILDAMKM
EHTIAAECAGRVIDVRVGATGQTVEGQILLVLEPVADAGVAHHRSEAADPRAIRPDLQRVRDRDAFLDDAARPDAVAKRH
ARGQRTARENVADLCDAGSFVEYGAYAVAAQASRRSAEDLIANTPADGLITGTGRINGTRFAPERARCAVLAYDATVLAG
TQGKRNHIKTDRILQVAAEQKLPTVIFAEGGGGRPGDVDFPTVAGLYQPSFAAFAALSGEVPVIGIAAGRCFAGNAALLG
CSDVIIATRDANIGMAGPAMIEGGGLGVYRPEDIGPAAVQYQNGVVDLLVDDEAEAVRAAKHYLSMFQGRTQDWEAPDAL
MLRGVVPENRLRVYDTRAAIQGIADVGSVIELRAGYGTGVHTALARIEGRPVGIVANNPRHLGGAIDVDGADKAARFMQL
CDTHGLPIVSLIDTPGFMVGPEIEARAQVRHVSRLFVLGAKVRVPFMAVVLRKGYGLGAMAMAAGGFRAPAFTISWPTGE
FGGMGLEGAVRLGFRKELEALPAGPERDALYQQLVAQMYERGHAINAAAGLEIDAVIDPAETRRWLLAGLDAAPRDEAPR
RYVDAW

Sequences:

>Translated_1126_residues
MQLDARALHSGLHPGGTASIPHGIEPVKKLLIANRGEIALRVQRAAQDLGIATVAVYATDDAQSRHRQLADEAIALPGNG
PATYLDIDAILGAARAAGCDAIHPGYGFLSERADFAQACAAAGITFVGPTPEQLALFGDKGRALELAAQCDVPVMPATPG
GASLDDVRAFFAAQQGNGIVLKAVGGGGGRGMRVVRDAEALAEAYARCQSEARSAFGIEAIYAERLVERARHIEVQIIGD
GTETIALGERDCTLQRRFQKLVEIAPSPVLTPALRDRIVQAASRIAKHTGYRSLGTFEFLVETDDAGTPHGFVFIEANPR
LQVEHTITEQVTGLDLVALQLGLADGRSLRDLGLDPAAPPTARGFSVQLRINAEATDAQGQARPALGRLERFDPPTGPDV
RVDTHGYTGYAPPAGYDSLLAKLIVSTSSPRFEDVVRRVRRALGECRVDGVPSNLDLLRALVAREDFATQHVHTRHFEAI
LPELLTAAQRVAASDAARQASIGIAQTAPVPVPTATAEAIDEGLVAVRAPMNGRVVEMRVQEDDIVQPGQIVAILDAMKM
EHTIAAECAGRVIDVRVGATGQTVEGQILLVLEPVADAGVAHHRSEAADPRAIRPDLQRVRDRDAFLDDAARPDAVAKRH
ARGQRTARENVADLCDAGSFVEYGAYAVAAQASRRSAEDLIANTPADGLITGTGRINGTRFAPERARCAVLAYDATVLAG
TQGKRNHIKTDRILQVAAEQKLPTVIFAEGGGGRPGDVDFPTVAGLYQPSFAAFAALSGEVPVIGIAAGRCFAGNAALLG
CSDVIIATRDANIGMAGPAMIEGGGLGVYRPEDIGPAAVQYQNGVVDLLVDDEAEAVRAAKHYLSMFQGRTQDWEAPDAL
MLRGVVPENRLRVYDTRAAIQGIADVGSVIELRAGYGTGVHTALARIEGRPVGIVANNPRHLGGAIDVDGADKAARFMQL
CDTHGLPIVSLIDTPGFMVGPEIEARAQVRHVSRLFVLGAKVRVPFMAVVLRKGYGLGAMAMAAGGFRAPAFTISWPTGE
FGGMGLEGAVRLGFRKELEALPAGPERDALYQQLVAQMYERGHAINAAAGLEIDAVIDPAETRRWLLAGLDAAPRDEAPR
RYVDAW
>Mature_1126_residues
MQLDARALHSGLHPGGTASIPHGIEPVKKLLIANRGEIALRVQRAAQDLGIATVAVYATDDAQSRHRQLADEAIALPGNG
PATYLDIDAILGAARAAGCDAIHPGYGFLSERADFAQACAAAGITFVGPTPEQLALFGDKGRALELAAQCDVPVMPATPG
GASLDDVRAFFAAQQGNGIVLKAVGGGGGRGMRVVRDAEALAEAYARCQSEARSAFGIEAIYAERLVERARHIEVQIIGD
GTETIALGERDCTLQRRFQKLVEIAPSPVLTPALRDRIVQAASRIAKHTGYRSLGTFEFLVETDDAGTPHGFVFIEANPR
LQVEHTITEQVTGLDLVALQLGLADGRSLRDLGLDPAAPPTARGFSVQLRINAEATDAQGQARPALGRLERFDPPTGPDV
RVDTHGYTGYAPPAGYDSLLAKLIVSTSSPRFEDVVRRVRRALGECRVDGVPSNLDLLRALVAREDFATQHVHTRHFEAI
LPELLTAAQRVAASDAARQASIGIAQTAPVPVPTATAEAIDEGLVAVRAPMNGRVVEMRVQEDDIVQPGQIVAILDAMKM
EHTIAAECAGRVIDVRVGATGQTVEGQILLVLEPVADAGVAHHRSEAADPRAIRPDLQRVRDRDAFLDDAARPDAVAKRH
ARGQRTARENVADLCDAGSFVEYGAYAVAAQASRRSAEDLIANTPADGLITGTGRINGTRFAPERARCAVLAYDATVLAG
TQGKRNHIKTDRILQVAAEQKLPTVIFAEGGGGRPGDVDFPTVAGLYQPSFAAFAALSGEVPVIGIAAGRCFAGNAALLG
CSDVIIATRDANIGMAGPAMIEGGGLGVYRPEDIGPAAVQYQNGVVDLLVDDEAEAVRAAKHYLSMFQGRTQDWEAPDAL
MLRGVVPENRLRVYDTRAAIQGIADVGSVIELRAGYGTGVHTALARIEGRPVGIVANNPRHLGGAIDVDGADKAARFMQL
CDTHGLPIVSLIDTPGFMVGPEIEARAQVRHVSRLFVLGAKVRVPFMAVVLRKGYGLGAMAMAAGGFRAPAFTISWPTGE
FGGMGLEGAVRLGFRKELEALPAGPERDALYQQLVAQMYERGHAINAAAGLEIDAVIDPAETRRWLLAGLDAAPRDEAPR
RYVDAW

Specific function: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second, leading to oxaloacetate production. Fulfills an anaplerotic functi

COG id: COG4799

COG function: function code I; Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=531, Percent_Identity=42.7495291902072, Blast_Score=327, Evalue=3e-89,
Organism=Homo sapiens, GI106049295, Length=531, Percent_Identity=42.7495291902072, Blast_Score=327, Evalue=3e-89,
Organism=Homo sapiens, GI106049292, Length=531, Percent_Identity=42.7495291902072, Blast_Score=327, Evalue=3e-89,
Organism=Homo sapiens, GI116805327, Length=501, Percent_Identity=35.7285429141717, Blast_Score=291, Evalue=2e-78,
Organism=Homo sapiens, GI189095269, Length=475, Percent_Identity=35.7894736842105, Blast_Score=262, Evalue=1e-69,
Organism=Homo sapiens, GI65506442, Length=470, Percent_Identity=36.1702127659575, Blast_Score=262, Evalue=1e-69,
Organism=Homo sapiens, GI295821183, Length=470, Percent_Identity=36.1702127659575, Blast_Score=262, Evalue=2e-69,
Organism=Homo sapiens, GI38679960, Length=528, Percent_Identity=28.219696969697, Blast_Score=171, Evalue=5e-42,
Organism=Homo sapiens, GI38679974, Length=528, Percent_Identity=28.219696969697, Blast_Score=170, Evalue=6e-42,
Organism=Homo sapiens, GI38679971, Length=528, Percent_Identity=28.219696969697, Blast_Score=170, Evalue=7e-42,
Organism=Homo sapiens, GI38679977, Length=528, Percent_Identity=28.219696969697, Blast_Score=170, Evalue=7e-42,
Organism=Homo sapiens, GI38679967, Length=528, Percent_Identity=28.219696969697, Blast_Score=170, Evalue=7e-42,
Organism=Homo sapiens, GI134142062, Length=527, Percent_Identity=28.4629981024668, Blast_Score=167, Evalue=8e-41,
Organism=Homo sapiens, GI119943100, Length=495, Percent_Identity=26.8686868686869, Blast_Score=163, Evalue=9e-40,
Organism=Homo sapiens, GI295821216, Length=508, Percent_Identity=26.3779527559055, Blast_Score=159, Evalue=2e-38,
Organism=Homo sapiens, GI11545863, Length=506, Percent_Identity=28.6561264822134, Blast_Score=144, Evalue=6e-34,
Organism=Escherichia coli, GI1789654, Length=458, Percent_Identity=41.9213973799127, Blast_Score=303, Evalue=3e-83,
Organism=Caenorhabditis elegans, GI17562816, Length=462, Percent_Identity=44.5887445887446, Blast_Score=327, Evalue=2e-89,
Organism=Caenorhabditis elegans, GI71987519, Length=454, Percent_Identity=38.1057268722467, Blast_Score=282, Evalue=7e-76,
Organism=Caenorhabditis elegans, GI17567343, Length=471, Percent_Identity=36.7303609341826, Blast_Score=264, Evalue=2e-70,
Organism=Caenorhabditis elegans, GI25147359, Length=494, Percent_Identity=27.5303643724696, Blast_Score=170, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI25147362, Length=494, Percent_Identity=27.5303643724696, Blast_Score=170, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI17552936, Length=519, Percent_Identity=27.3603082851638, Blast_Score=163, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI71997168, Length=430, Percent_Identity=28.6046511627907, Blast_Score=162, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI71997163, Length=430, Percent_Identity=28.6046511627907, Blast_Score=161, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI133931226, Length=505, Percent_Identity=26.9306930693069, Blast_Score=161, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6319695, Length=446, Percent_Identity=43.2735426008969, Blast_Score=308, Evalue=4e-84,
Organism=Saccharomyces cerevisiae, GI6321376, Length=446, Percent_Identity=43.7219730941704, Blast_Score=302, Evalue=2e-82,
Organism=Saccharomyces cerevisiae, GI6319685, Length=451, Percent_Identity=38.1374722838137, Blast_Score=272, Evalue=2e-73,
Organism=Saccharomyces cerevisiae, GI6323863, Length=404, Percent_Identity=30.1980198019802, Blast_Score=156, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6324343, Length=359, Percent_Identity=31.7548746518106, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI281363050, Length=449, Percent_Identity=43.652561247216, Blast_Score=327, Evalue=3e-89,
Organism=Drosophila melanogaster, GI24652224, Length=449, Percent_Identity=43.652561247216, Blast_Score=327, Evalue=3e-89,
Organism=Drosophila melanogaster, GI24652222, Length=449, Percent_Identity=43.652561247216, Blast_Score=327, Evalue=3e-89,
Organism=Drosophila melanogaster, GI24652220, Length=449, Percent_Identity=43.652561247216, Blast_Score=327, Evalue=3e-89,
Organism=Drosophila melanogaster, GI24652218, Length=449, Percent_Identity=43.652561247216, Blast_Score=327, Evalue=3e-89,
Organism=Drosophila melanogaster, GI24652212, Length=449, Percent_Identity=43.652561247216, Blast_Score=327, Evalue=4e-89,
Organism=Drosophila melanogaster, GI24652210, Length=449, Percent_Identity=43.652561247216, Blast_Score=327, Evalue=4e-89,
Organism=Drosophila melanogaster, GI24652214, Length=449, Percent_Identity=43.652561247216, Blast_Score=327, Evalue=4e-89,
Organism=Drosophila melanogaster, GI19921944, Length=449, Percent_Identity=43.652561247216, Blast_Score=327, Evalue=4e-89,
Organism=Drosophila melanogaster, GI24652216, Length=449, Percent_Identity=43.652561247216, Blast_Score=327, Evalue=4e-89,
Organism=Drosophila melanogaster, GI24651757, Length=476, Percent_Identity=37.3949579831933, Blast_Score=281, Evalue=2e-75,
Organism=Drosophila melanogaster, GI24651759, Length=434, Percent_Identity=35.9447004608295, Blast_Score=238, Evalue=2e-62,
Organism=Drosophila melanogaster, GI24586065, Length=563, Percent_Identity=28.5968028419183, Blast_Score=152, Evalue=1e-36,
Organism=Drosophila melanogaster, GI161076409, Length=446, Percent_Identity=28.9237668161435, Blast_Score=149, Evalue=8e-36,
Organism=Drosophila melanogaster, GI161076407, Length=446, Percent_Identity=28.9237668161435, Blast_Score=149, Evalue=8e-36,
Organism=Drosophila melanogaster, GI24586460, Length=446, Percent_Identity=28.9237668161435, Blast_Score=149, Evalue=8e-36,
Organism=Drosophila melanogaster, GI24586458, Length=446, Percent_Identity=28.9237668161435, Blast_Score=149, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR000089
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR003379
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR000891
- InterPro:   IPR005930
- InterPro:   IPR011054
- InterPro:   IPR011053 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00364 Biotin_lipoyl; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =6.4.1.1 [H]

Molecular weight: Translated: 119224; Mature: 119224

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS50975 ATP_GRASP ; PS00867 CPSASE_2 ; PS50979 BC ; PS50980 COA_CT_NTER ; PS50989 COA_CT_CTER ; PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLDARALHSGLHPGGTASIPHGIEPVKKLLIANRGEIALRVQRAAQDLGIATVAVYATD
CCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEHHHHHHCCEEEEEEEECC
DAQSRHRQLADEAIALPGNGPATYLDIDAILGAARAAGCDAIHPGYGFLSERADFAQACA
CHHHHHHHHHHHEEECCCCCCEEEEEHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
AAGITFVGPTPEQLALFGDKGRALELAAQCDVPVMPATPGGASLDDVRAFFAAQQGNGIV
HCCEEEECCCHHHEEEECCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEE
LKAVGGGGGRGMRVVRDAEALAEAYARCQSEARSAFGIEAIYAERLVERARHIEVQIIGD
EEEECCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEEEEEEEC
GTETIALGERDCTLQRRFQKLVEIAPSPVLTPALRDRIVQAASRIAKHTGYRSLGTFEFL
CCCEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
VETDDAGTPHGFVFIEANPRLQVEHTITEQVTGLDLVALQLGLADGRSLRDLGLDPAAPP
EECCCCCCCCEEEEEECCCCEEEEEEHHHHHCCCEEEEEECCCCCCCCHHHCCCCCCCCC
TARGFSVQLRINAEATDAQGQARPALGRLERFDPPTGPDVRVDTHGYTGYAPPAGYDSLL
CCCCEEEEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCHHHHH
AKLIVSTSSPRFEDVVRRVRRALGECRVDGVPSNLDLLRALVAREDFATQHVHTRHFEAI
HHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LPELLTAAQRVAASDAARQASIGIAQTAPVPVPTATAEAIDEGLVAVRAPMNGRVVEMRV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCEEEECCCCCCEEEEEE
QEDDIVQPGQIVAILDAMKMEHTIAAECAGRVIDVRVGATGQTVEGQILLVLEPVADAGV
CCCCCCCCCCEEEHHHHHHHHHHHHHHHCCCEEEEEECCCCCEECCEEEEEEECCCCCCH
AHHRSEAADPRAIRPDLQRVRDRDAFLDDAARPDAVAKRHARGQRTARENVADLCDAGSF
HHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCH
VEYGAYAVAAQASRRSAEDLIANTPADGLITGTGRINGTRFAPERARCAVLAYDATVLAG
HHHCHHHEEHHHHHCCHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCEEEEEECCEEEEC
TQGKRNHIKTDRILQVAAEQKLPTVIFAEGGGGRPGDVDFPTVAGLYQPSFAAFAALSGE
CCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHCCCCCCHHHHHHHCCC
VPVIGIAAGRCFAGNAALLGCSDVIIATRDANIGMAGPAMIEGGGLGVYRPEDIGPAAVQ
CCEEEEECCCEECCCEEEEECCEEEEEEECCCCCCCCCCEEECCCCCCCCCCCCCCHHEE
YQNGVVDLLVDDEAEAVRAAKHYLSMFQGRTQDWEAPDALMLRGVVPENRLRVYDTRAAI
ECCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCHHEEECCCCCCCEEEEEHHHHH
QGIADVGSVIELRAGYGTGVHTALARIEGRPVGIVANNPRHLGGAIDVDGADKAARFMQL
HHHHHHCCCEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCCEEECCCCHHHHHHHHH
CDTHGLPIVSLIDTPGFMVGPEIEARAQVRHVSRLFVLGAKVRVPFMAVVLRKGYGLGAM
HHCCCCCEEEEECCCCCEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHH
AMAAGGFRAPAFTISWPTGEFGGMGLEGAVRLGFRKELEALPAGPERDALYQQLVAQMYE
HHHCCCCCCCEEEEECCCCCCCCCCCCHHHHHCHHHHHHHCCCCCCHHHHHHHHHHHHHH
RGHAINAAAGLEIDAVIDPAETRRWLLAGLDAAPRDEAPRRYVDAW
CCCEEECCCCCEEEEEECCHHHHHHHHCCCCCCCCCCCCCHHCCCC
>Mature Secondary Structure
MQLDARALHSGLHPGGTASIPHGIEPVKKLLIANRGEIALRVQRAAQDLGIATVAVYATD
CCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEHHHHHHCCEEEEEEEECC
DAQSRHRQLADEAIALPGNGPATYLDIDAILGAARAAGCDAIHPGYGFLSERADFAQACA
CHHHHHHHHHHHEEECCCCCCEEEEEHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
AAGITFVGPTPEQLALFGDKGRALELAAQCDVPVMPATPGGASLDDVRAFFAAQQGNGIV
HCCEEEECCCHHHEEEECCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEE
LKAVGGGGGRGMRVVRDAEALAEAYARCQSEARSAFGIEAIYAERLVERARHIEVQIIGD
EEEECCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEEEEEEEC
GTETIALGERDCTLQRRFQKLVEIAPSPVLTPALRDRIVQAASRIAKHTGYRSLGTFEFL
CCCEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
VETDDAGTPHGFVFIEANPRLQVEHTITEQVTGLDLVALQLGLADGRSLRDLGLDPAAPP
EECCCCCCCCEEEEEECCCCEEEEEEHHHHHCCCEEEEEECCCCCCCCHHHCCCCCCCCC
TARGFSVQLRINAEATDAQGQARPALGRLERFDPPTGPDVRVDTHGYTGYAPPAGYDSLL
CCCCEEEEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCHHHHH
AKLIVSTSSPRFEDVVRRVRRALGECRVDGVPSNLDLLRALVAREDFATQHVHTRHFEAI
HHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LPELLTAAQRVAASDAARQASIGIAQTAPVPVPTATAEAIDEGLVAVRAPMNGRVVEMRV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCEEEECCCCCCEEEEEE
QEDDIVQPGQIVAILDAMKMEHTIAAECAGRVIDVRVGATGQTVEGQILLVLEPVADAGV
CCCCCCCCCCEEEHHHHHHHHHHHHHHHCCCEEEEEECCCCCEECCEEEEEEECCCCCCH
AHHRSEAADPRAIRPDLQRVRDRDAFLDDAARPDAVAKRHARGQRTARENVADLCDAGSF
HHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCH
VEYGAYAVAAQASRRSAEDLIANTPADGLITGTGRINGTRFAPERARCAVLAYDATVLAG
HHHCHHHEEHHHHHCCHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCEEEEEECCEEEEC
TQGKRNHIKTDRILQVAAEQKLPTVIFAEGGGGRPGDVDFPTVAGLYQPSFAAFAALSGE
CCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHCCCCCCHHHHHHHCCC
VPVIGIAAGRCFAGNAALLGCSDVIIATRDANIGMAGPAMIEGGGLGVYRPEDIGPAAVQ
CCEEEEECCCEECCCEEEEECCEEEEEEECCCCCCCCCCEEECCCCCCCCCCCCCCHHEE
YQNGVVDLLVDDEAEAVRAAKHYLSMFQGRTQDWEAPDALMLRGVVPENRLRVYDTRAAI
ECCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCHHEEECCCCCCCEEEEEHHHHH
QGIADVGSVIELRAGYGTGVHTALARIEGRPVGIVANNPRHLGGAIDVDGADKAARFMQL
HHHHHHCCCEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCCEEECCCCHHHHHHHHH
CDTHGLPIVSLIDTPGFMVGPEIEARAQVRHVSRLFVLGAKVRVPFMAVVLRKGYGLGAM
HHCCCCCEEEEECCCCCEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHH
AMAAGGFRAPAFTISWPTGEFGGMGLEGAVRLGFRKELEALPAGPERDALYQQLVAQMYE
HHHCCCCCCCEEEEECCCCCCCCCCCCHHHHHCHHHHHHHCCCCCCHHHHHHHHHHHHHH
RGHAINAAAGLEIDAVIDPAETRRWLLAGLDAAPRDEAPRRYVDAW
CCCEEECCCCCEEEEEECCHHHHHHHHCCCCCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]