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The map label for this gene is cph2 [H]

Identifier: 94312895

GI number: 94312895

Start: 529677

End: 530684

Strand: Reverse

Name: cph2 [H]

Synonym: Rmet_3967

Alternate gene names: 94312895

Gene position: 530684-529677 (Counterclockwise)

Preceding gene: 94312896

Following gene: 94312894

Centisome position: 20.57

GC content: 63.1

Gene sequence:

>1008_bases
ATGCCCAGACAACTCAATTCGGCCGATGCGGCGGCCACCCATGAATACCCGGCAATGGTGCTGCTGGTCGACGACCAGGC
CATCATCGGCGAGGCTATCCGGCGTGCGCTGGCCAGCGAGTCCGATATCGACTTCCACTATTGCTCGCAGCCCGAAGAGG
CCGTGACGGTGGCCGAGCGCACCAAGCCCACCGTGATCTTGCAGGATCTGGTCATGCCCGGCACCGACGGGCTGACGTTG
GTGCGCCGCTACCGCGAAAACGCCACCACGCGCGATATTCCGATCATCGTGCTGTCGACGAAGGAAGAGCCCACCATGAA
GAGCGCGGCTTTCGCGGCCGGCGCCAACGACTATCTGGTGAAGCTTCCGGATTCGATCGAGTTGATCGCGCGAATCCGCT
ACCACTCTCGCTCTTACCTGAATCTGCTGCAACGTGACGAGGCATATCGGGCGCTGCGCCAAAGCCAGCAGCAATTGCTT
GAGACCAATCTCGAACTGCAGCGGCTAACCAATTCCGACGGACTGACCTCCCTGTCGAACCGTCGCTACTTCGACGAGTA
CCTGGGCGCGGAATGGAAACGCGCCCAGCGCGAACAGACCCAGCTCGCGCTACTGATGATCGACGTCGATGCATTCAAGG
GCTACAACGATACCTACGGCCACGTGGCGGGCGACGAGGTACTGCGCCGCGTGGCCGCCGTGATCCGCGAGAACTGCGCA
CGCCCGGCGGACCTGCCCGCGCGCTTCGGCGGTGAGGAATTCTCGATGATCCTGCCGGCCACATCGCCCGGCGGCGCACG
ACTGCTGGCCGAGAAGGTCAGGCGCGCGATCGAGACGCTGCGCATTCCGCATGCCTGCTCCCCAACTGGCGGATTTGTCA
CGGTCAGTATCGGCGGCGCGGTGATAGTGCCGGGAGGCGATGCCGATTTCAGCCGGCTGATAGAGGCTGCCGATGCTGGC
CTCTATCAGGCCAAGCGTAATGGACGAAACCAGGTAGTGATGGCGTAG

Upstream 100 bases:

>100_bases
GCGCGGCGAGCGAGATTCTGCCACTGCAGAAGATCGCGCCGCGGCTAGTCATGACGTGTGGTGGTGGTCGGCGGTAAAAG
AAAAGAACAGGAGGCGAATA

Downstream 100 bases:

>100_bases
TTCCGAATCTTCGGTTTCCTGGGCATCCAGTTTTTGGTTTCCACAGCCAAAGCCAACGTAGATCCTCGCCTGGGACGCGA
CAAGTCAACTCATTGATACG

Product: putative response regulator of a two-component system

Products: NA

Alternate protein names: Bacteriophytochrome cph2 [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MPRQLNSADAAATHEYPAMVLLVDDQAIIGEAIRRALASESDIDFHYCSQPEEAVTVAERTKPTVILQDLVMPGTDGLTL
VRRYRENATTRDIPIIVLSTKEEPTMKSAAFAAGANDYLVKLPDSIELIARIRYHSRSYLNLLQRDEAYRALRQSQQQLL
ETNLELQRLTNSDGLTSLSNRRYFDEYLGAEWKRAQREQTQLALLMIDVDAFKGYNDTYGHVAGDEVLRRVAAVIRENCA
RPADLPARFGGEEFSMILPATSPGGARLLAEKVRRAIETLRIPHACSPTGGFVTVSIGGAVIVPGGDADFSRLIEAADAG
LYQAKRNGRNQVVMA

Sequences:

>Translated_335_residues
MPRQLNSADAAATHEYPAMVLLVDDQAIIGEAIRRALASESDIDFHYCSQPEEAVTVAERTKPTVILQDLVMPGTDGLTL
VRRYRENATTRDIPIIVLSTKEEPTMKSAAFAAGANDYLVKLPDSIELIARIRYHSRSYLNLLQRDEAYRALRQSQQQLL
ETNLELQRLTNSDGLTSLSNRRYFDEYLGAEWKRAQREQTQLALLMIDVDAFKGYNDTYGHVAGDEVLRRVAAVIRENCA
RPADLPARFGGEEFSMILPATSPGGARLLAEKVRRAIETLRIPHACSPTGGFVTVSIGGAVIVPGGDADFSRLIEAADAG
LYQAKRNGRNQVVMA
>Mature_334_residues
PRQLNSADAAATHEYPAMVLLVDDQAIIGEAIRRALASESDIDFHYCSQPEEAVTVAERTKPTVILQDLVMPGTDGLTLV
RRYRENATTRDIPIIVLSTKEEPTMKSAAFAAGANDYLVKLPDSIELIARIRYHSRSYLNLLQRDEAYRALRQSQQQLLE
TNLELQRLTNSDGLTSLSNRRYFDEYLGAEWKRAQREQTQLALLMIDVDAFKGYNDTYGHVAGDEVLRRVAAVIRENCAR
PADLPARFGGEEFSMILPATSPGGARLLAEKVRRAIETLRIPHACSPTGGFVTVSIGGAVIVPGGDADFSRLIEAADAGL
YQAKRNGRNQVVMA

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG3706

COG function: function code T; Response regulator containing a CheY-like receiver domain and a GGDEF domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 GGDEF domains [H]

Homologues:

Organism=Escherichia coli, GI145693134, Length=160, Percent_Identity=40.625, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1786584, Length=184, Percent_Identity=33.695652173913, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1787262, Length=170, Percent_Identity=37.6470588235294, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI87081881, Length=183, Percent_Identity=40.4371584699454, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI87082007, Length=178, Percent_Identity=36.5168539325843, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787802, Length=167, Percent_Identity=37.125748502994, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787816, Length=165, Percent_Identity=30.9090909090909, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1788085, Length=182, Percent_Identity=30.2197802197802, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787541, Length=169, Percent_Identity=30.1775147928994, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788381, Length=179, Percent_Identity=29.608938547486, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1787056, Length=171, Percent_Identity=30.9941520467836, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1788956, Length=186, Percent_Identity=30.6451612903226, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR003018
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515 [H]

Pfam domain/function: PF00563 EAL; PF01590 GAF; PF00990 GGDEF; PF00360 Phytochrome [H]

EC number: NA

Molecular weight: Translated: 37005; Mature: 36874

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRQLNSADAAATHEYPAMVLLVDDQAIIGEAIRRALASESDIDFHYCSQPEEAVTVAER
CCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHC
TKPTVILQDLVMPGTDGLTLVRRYRENATTRDIPIIVLSTKEEPTMKSAAFAAGANDYLV
CCCCEEEHHHHCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHCCCCCEEE
KLPDSIELIARIRYHSRSYLNLLQRDEAYRALRQSQQQLLETNLELQRLTNSDGLTSLSN
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCHHHC
RRYFDEYLGAEWKRAQREQTQLALLMIDVDAFKGYNDTYGHVAGDEVLRRVAAVIRENCA
CHHHHHHHCHHHHHHHHHHHEEEEEEEEHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCC
RPADLPARFGGEEFSMILPATSPGGARLLAEKVRRAIETLRIPHACSPTGGFVTVSIGGA
CCCCCCHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCE
VIVPGGDADFSRLIEAADAGLYQAKRNGRNQVVMA
EEECCCCHHHHHHHHHHHCHHHHHHHCCCCEEEEC
>Mature Secondary Structure 
PRQLNSADAAATHEYPAMVLLVDDQAIIGEAIRRALASESDIDFHYCSQPEEAVTVAER
CCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHC
TKPTVILQDLVMPGTDGLTLVRRYRENATTRDIPIIVLSTKEEPTMKSAAFAAGANDYLV
CCCCEEEHHHHCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHCCCCCEEE
KLPDSIELIARIRYHSRSYLNLLQRDEAYRALRQSQQQLLETNLELQRLTNSDGLTSLSN
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCHHHC
RRYFDEYLGAEWKRAQREQTQLALLMIDVDAFKGYNDTYGHVAGDEVLRRVAAVIRENCA
CHHHHHHHCHHHHHHHHHHHEEEEEEEEHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCC
RPADLPARFGGEEFSMILPATSPGGARLLAEKVRRAIETLRIPHACSPTGGFVTVSIGGA
CCCCCCHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCE
VIVPGGDADFSRLIEAADAGLYQAKRNGRNQVVMA
EEECCCCHHHHHHHHHHHCHHHHHHHCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10978170; 11063585 [H]