| Definition | Cupriavidus metallidurans CH34 megaplasmid, complete sequence. |
|---|---|
| Accession | NC_007974 |
| Length | 2,580,084 |
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The map label for this gene is fabG [H]
Identifier: 94312602
GI number: 94312602
Start: 207798
End: 208529
Strand: Direct
Name: fabG [H]
Synonym: Rmet_3670
Alternate gene names: 94312602
Gene position: 207798-208529 (Clockwise)
Preceding gene: 94312601
Following gene: 94312603
Centisome position: 8.05
GC content: 65.71
Gene sequence:
>732_bases ATGTCCCTTCCTGTTGCCACCCTGGTCACTGGCGCCAGTTCCGGAATCGGCCGAGCCATTGCGGAAATGCTGCTCGCCGA TGGTGTGACGCGTGTCATCAACGTCGACTATGCAGCGCCGACGTGGTCGCACCCGAACATGACCTTTTTCCAGGCCGATC TGACCAATGCCGATGCCACGCGCGCGGTGGCGGAGCAGGTGACGTCTCAGTTCGCCGTGACGCGGCTCGTCAACAATGCC GGCGCCACGCGCCCCGGCACGGCTGACACGGCCACGGCGGAAGATCTCGATTACGTCGTGGGCCTGACCCTGCAGGCCAC GATGCTGCTGACACAGGCCTGCCTGCCCGCGATGCGCGCGGCGGGGTTTGGCCGCATCGTCAACATGGCTTCGCGCGCGG CGCTGGGCAAGCCCGAACGCGTGGTGTATTCCGCTGCCAAGGCTGGGCTGGTTGGCATGACCCGAACGCTGGCGATGGAG CTGGGCGGCGACGGCATCACCGTCAACGCCGTGGCACCGGGTCCCATCGCCACCGAGCTGTTCCGCCGGAGTAATCCGGA GGGCAGCGAACAGACACGGCGCATTCTCGCAAGCATCGCCGTGAAACGCATGGGAACGCCGGAAGACGTGGCGCGTGCCT CGCTGTTCTTCCTTGCACCCGAGAATGGTTTCGTGACGGGACAGGTCCTGTACGTCTGCGGCGGAACCACGCTGGGTGTG GCACCCGTATAA
Upstream 100 bases:
>100_bases CAACGAGGTAGAGCATCGCGGCCAGGCCGACGGGCTCGCCGGCTTCGCCGCATTTTTTCTGATTTGACCGGCCGCTTGCG TGCCGGTGCGGAGTACCGAG
Downstream 100 bases:
>100_bases GAAAGTGCCCGCCCCCCAGGCACGGGGCGGAATAGCGGTTCAAAGCATTACGTCCGCAGTAAGCCAGATGGCTAGCGGAC GTGCATCACTCCTGGAGCAC
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 243; Mature: 242
Protein sequence:
>243_residues MSLPVATLVTGASSGIGRAIAEMLLADGVTRVINVDYAAPTWSHPNMTFFQADLTNADATRAVAEQVTSQFAVTRLVNNA GATRPGTADTATAEDLDYVVGLTLQATMLLTQACLPAMRAAGFGRIVNMASRAALGKPERVVYSAAKAGLVGMTRTLAME LGGDGITVNAVAPGPIATELFRRSNPEGSEQTRRILASIAVKRMGTPEDVARASLFFLAPENGFVTGQVLYVCGGTTLGV APV
Sequences:
>Translated_243_residues MSLPVATLVTGASSGIGRAIAEMLLADGVTRVINVDYAAPTWSHPNMTFFQADLTNADATRAVAEQVTSQFAVTRLVNNA GATRPGTADTATAEDLDYVVGLTLQATMLLTQACLPAMRAAGFGRIVNMASRAALGKPERVVYSAAKAGLVGMTRTLAME LGGDGITVNAVAPGPIATELFRRSNPEGSEQTRRILASIAVKRMGTPEDVARASLFFLAPENGFVTGQVLYVCGGTTLGV APV >Mature_242_residues SLPVATLVTGASSGIGRAIAEMLLADGVTRVINVDYAAPTWSHPNMTFFQADLTNADATRAVAEQVTSQFAVTRLVNNAG ATRPGTADTATAEDLDYVVGLTLQATMLLTQACLPAMRAAGFGRIVNMASRAALGKPERVVYSAAKAGLVGMTRTLAMEL GGDGITVNAVAPGPIATELFRRSNPEGSEQTRRILASIAVKRMGTPEDVARASLFFLAPENGFVTGQVLYVCGGTTLGVA PV
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=247, Percent_Identity=34.8178137651822, Blast_Score=113, Evalue=2e-25, Organism=Homo sapiens, GI32483357, Length=241, Percent_Identity=33.195020746888, Blast_Score=98, Evalue=6e-21, Organism=Homo sapiens, GI40254992, Length=237, Percent_Identity=32.4894514767932, Blast_Score=93, Evalue=3e-19, Organism=Homo sapiens, GI19923817, Length=252, Percent_Identity=28.968253968254, Blast_Score=92, Evalue=5e-19, Organism=Homo sapiens, GI66933014, Length=170, Percent_Identity=32.3529411764706, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI59889578, Length=201, Percent_Identity=31.3432835820896, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI5031737, Length=241, Percent_Identity=30.2904564315353, Blast_Score=74, Evalue=8e-14, Organism=Homo sapiens, GI126723750, Length=247, Percent_Identity=28.7449392712551, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI7705925, Length=237, Percent_Identity=31.2236286919831, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI31542939, Length=195, Percent_Identity=32.3076923076923, Blast_Score=68, Evalue=8e-12, Organism=Homo sapiens, GI10190704, Length=244, Percent_Identity=27.8688524590164, Blast_Score=67, Evalue=2e-11, Organism=Escherichia coli, GI1787335, Length=236, Percent_Identity=36.0169491525424, Blast_Score=119, Evalue=1e-28, Organism=Escherichia coli, GI87082100, Length=247, Percent_Identity=31.1740890688259, Blast_Score=101, Evalue=6e-23, Organism=Escherichia coli, GI1789208, Length=238, Percent_Identity=30.2521008403361, Blast_Score=92, Evalue=2e-20, Organism=Escherichia coli, GI87082160, Length=245, Percent_Identity=31.0204081632653, Blast_Score=92, Evalue=4e-20, Organism=Escherichia coli, GI1787905, Length=238, Percent_Identity=31.9327731092437, Blast_Score=89, Evalue=4e-19, Organism=Escherichia coli, GI2367175, Length=244, Percent_Identity=31.5573770491803, Blast_Score=86, Evalue=2e-18, Organism=Escherichia coli, GI2367365, Length=230, Percent_Identity=30.4347826086957, Blast_Score=80, Evalue=9e-17, Organism=Escherichia coli, GI1790717, Length=243, Percent_Identity=26.7489711934156, Blast_Score=77, Evalue=7e-16, Organism=Escherichia coli, GI1789378, Length=252, Percent_Identity=27.3809523809524, Blast_Score=75, Evalue=4e-15, Organism=Escherichia coli, GI1786812, Length=242, Percent_Identity=28.5123966942149, Blast_Score=70, Evalue=9e-14, Organism=Escherichia coli, GI1788459, Length=243, Percent_Identity=28.8065843621399, Blast_Score=69, Evalue=3e-13, Organism=Escherichia coli, GI1789057, Length=254, Percent_Identity=26.7716535433071, Blast_Score=64, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17561402, Length=243, Percent_Identity=30.0411522633745, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI25147288, Length=245, Percent_Identity=31.0204081632653, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17560676, Length=240, Percent_Identity=30, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI71994600, Length=257, Percent_Identity=28.7937743190661, Blast_Score=84, Evalue=9e-17, Organism=Caenorhabditis elegans, GI17559104, Length=258, Percent_Identity=30.2325581395349, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17562910, Length=260, Percent_Identity=29.6153846153846, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17562904, Length=260, Percent_Identity=30.7692307692308, Blast_Score=81, Evalue=4e-16, Organism=Caenorhabditis elegans, GI71994604, Length=252, Percent_Identity=29.7619047619048, Blast_Score=81, Evalue=5e-16, Organism=Caenorhabditis elegans, GI115534694, Length=248, Percent_Identity=29.8387096774194, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17538480, Length=261, Percent_Identity=29.8850574712644, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17555706, Length=237, Percent_Identity=29.1139240506329, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17560332, Length=259, Percent_Identity=28.957528957529, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17551412, Length=258, Percent_Identity=29.4573643410853, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17538486, Length=257, Percent_Identity=27.6264591439689, Blast_Score=74, Evalue=9e-14, Organism=Caenorhabditis elegans, GI17563726, Length=260, Percent_Identity=29.2307692307692, Blast_Score=74, Evalue=9e-14, Organism=Caenorhabditis elegans, GI17560150, Length=260, Percent_Identity=30.7692307692308, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17562990, Length=258, Percent_Identity=30.2325581395349, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17544670, Length=262, Percent_Identity=26.7175572519084, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17565030, Length=261, Percent_Identity=30.6513409961686, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI72000259, Length=262, Percent_Identity=28.6259541984733, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17561272, Length=142, Percent_Identity=31.6901408450704, Blast_Score=65, Evalue=5e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=247, Percent_Identity=30.3643724696356, Blast_Score=73, Evalue=4e-14, Organism=Saccharomyces cerevisiae, GI6324126, Length=138, Percent_Identity=33.3333333333333, Blast_Score=71, Evalue=2e-13, Organism=Saccharomyces cerevisiae, GI6323882, Length=209, Percent_Identity=32.0574162679426, Blast_Score=66, Evalue=5e-12, Organism=Drosophila melanogaster, GI24639444, Length=240, Percent_Identity=33.75, Blast_Score=99, Evalue=3e-21, Organism=Drosophila melanogaster, GI23397609, Length=238, Percent_Identity=31.9327731092437, Blast_Score=94, Evalue=8e-20, Organism=Drosophila melanogaster, GI21355319, Length=241, Percent_Identity=28.2157676348548, Blast_Score=92, Evalue=2e-19, Organism=Drosophila melanogaster, GI24644339, Length=244, Percent_Identity=31.5573770491803, Blast_Score=82, Evalue=4e-16, Organism=Drosophila melanogaster, GI24643142, Length=244, Percent_Identity=28.6885245901639, Blast_Score=79, Evalue=3e-15, Organism=Drosophila melanogaster, GI21357041, Length=242, Percent_Identity=29.3388429752066, Blast_Score=74, Evalue=8e-14, Organism=Drosophila melanogaster, GI28571526, Length=242, Percent_Identity=28.9256198347107, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI18859837, Length=184, Percent_Identity=28.804347826087, Blast_Score=65, Evalue=3e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 25202; Mature: 25071
Theoretical pI: Translated: 7.25; Mature: 7.25
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 3.7 %Met (Translated Protein) 4.5 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 3.3 %Met (Mature Protein) 4.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSLPVATLVTGASSGIGRAIAEMLLADGVTRVINVDYAAPTWSHPNMTFFQADLTNADAT CCCCHHHHHHCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEEEEECCCCHHH RAVAEQVTSQFAVTRLVNNAGATRPGTADTATAEDLDYVVGLTLQATMLLTQACLPAMRA HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH AGFGRIVNMASRAALGKPERVVYSAAKAGLVGMTRTLAMELGGDGITVNAVAPGPIATEL CCHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEECCCHHHHHH FRRSNPEGSEQTRRILASIAVKRMGTPEDVARASLFFLAPENGFVTGQVLYVCGGTTLGV HHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHEEEEEECCCCCCEEEEEEEEECCCEECC APV CCC >Mature Secondary Structure SLPVATLVTGASSGIGRAIAEMLLADGVTRVINVDYAAPTWSHPNMTFFQADLTNADAT CCCHHHHHHCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEEEEECCCCHHH RAVAEQVTSQFAVTRLVNNAGATRPGTADTATAEDLDYVVGLTLQATMLLTQACLPAMRA HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH AGFGRIVNMASRAALGKPERVVYSAAKAGLVGMTRTLAMELGGDGITVNAVAPGPIATEL CCHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEECCCHHHHHH FRRSNPEGSEQTRRILASIAVKRMGTPEDVARASLFFLAPENGFVTGQVLYVCGGTTLGV HHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHEEEEEECCCCCCEEEEEEEEECCCEECC APV CCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 10360571 [H]