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The map label for this gene is mprA [H]

Identifier: 94312555

GI number: 94312555

Start: 159161

End: 159658

Strand: Reverse

Name: mprA [H]

Synonym: Rmet_3623

Alternate gene names: 94312555

Gene position: 159658-159161 (Counterclockwise)

Preceding gene: 94312556

Following gene: 94312554

Centisome position: 6.19

GC content: 64.66

Gene sequence:

>498_bases
ATGTCATTCGAGCGTCGCATTGATCGCTTTTGCGCGGAGTATCCGGAAGCGCCCCGTGACCTGATCCTGGCATCGCGGCT
ATTGCTGAGGTCGGCACGGCTGCTGCGCCAGCATATCGAACGGGCGCTCGCCGTACATGATCTCGACCTGAACCAGTACC
TCGTCATCAGCATGCTGGGGATCGACGCCATGGAACCGACCATGCCGTCCGAGCTGGGACTGACGATCGATGCCACGCGC
ACTCAGATGACCCGCCTCATCGACGGGCTCGAGACGCGCGGACTGGTCCAGCGCAAGGCTTCGCAGCACGACCGGCGCAG
CCTCGAGCTCATCCTCACCCCCGCCGCCCACGACTTGCTCAAGCGTGCCGCACCGACAGTCCATGCCGCCTACGCCGAAG
CTTGGGCCCCCATCGGCAAGACCGGTCTGGCAGCCGTCACGCGCGATCTCGGTCGGCTACATCAGCATCTGGCTGCGCTG
GGAGCAAACGCATCGTGA

Upstream 100 bases:

>100_bases
AGGCACTGCGGTAATCAGTCCTTTCACGCTTCACCTTGCCAAAGGTCTGCACGCGACATATAGTTTCATCCGTAACTATT
ACAGATGAAATCATACAGTC

Downstream 100 bases:

>100_bases
CCGCGCAGGCAGACCCGTGGCATCGGCTGCGCGCCCGCATGAGGTGGCTGCGCCTGCTCAGCCACCAGCAGCGGCAGACG
TTGCTCATGATCTTGCTGGG

Product: MarR-family transcriptional regulator

Products: NA

Alternate protein names: Protein emrR [H]

Number of amino acids: Translated: 165; Mature: 164

Protein sequence:

>165_residues
MSFERRIDRFCAEYPEAPRDLILASRLLLRSARLLRQHIERALAVHDLDLNQYLVISMLGIDAMEPTMPSELGLTIDATR
TQMTRLIDGLETRGLVQRKASQHDRRSLELILTPAAHDLLKRAAPTVHAAYAEAWAPIGKTGLAAVTRDLGRLHQHLAAL
GANAS

Sequences:

>Translated_165_residues
MSFERRIDRFCAEYPEAPRDLILASRLLLRSARLLRQHIERALAVHDLDLNQYLVISMLGIDAMEPTMPSELGLTIDATR
TQMTRLIDGLETRGLVQRKASQHDRRSLELILTPAAHDLLKRAAPTVHAAYAEAWAPIGKTGLAAVTRDLGRLHQHLAAL
GANAS
>Mature_164_residues
SFERRIDRFCAEYPEAPRDLILASRLLLRSARLLRQHIERALAVHDLDLNQYLVISMLGIDAMEPTMPSELGLTIDATRT
QMTRLIDGLETRGLVQRKASQHDRRSLELILTPAAHDLLKRAAPTVHAAYAEAWAPIGKTGLAAVTRDLGRLHQHLAALG
ANAS

Specific function: Negative regulator of the multidrug operon emrAB [H]

COG id: COG1846

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH marR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789040, Length=148, Percent_Identity=30.4054054054054, Blast_Score=70, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR023187
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR [H]

EC number: NA

Molecular weight: Translated: 18333; Mature: 18201

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: PS01117 HTH_MARR_1 ; PS50995 HTH_MARR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFERRIDRFCAEYPEAPRDLILASRLLLRSARLLRQHIERALAVHDLDLNQYLVISMLG
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
IDAMEPTMPSELGLTIDATRTQMTRLIDGLETRGLVQRKASQHDRRSLELILTPAAHDLL
CCCCCCCCCHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECHHHHHHH
KRAAPTVHAAYAEAWAPIGKTGLAAVTRDLGRLHQHLAALGANAS
HHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SFERRIDRFCAEYPEAPRDLILASRLLLRSARLLRQHIERALAVHDLDLNQYLVISMLG
CHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
IDAMEPTMPSELGLTIDATRTQMTRLIDGLETRGLVQRKASQHDRRSLELILTPAAHDLL
CCCCCCCCCHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECHHHHHHH
KRAAPTVHAAYAEAWAPIGKTGLAAVTRDLGRLHQHLAALGANAS
HHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]