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The map label for this gene is yafC [H]

Identifier: 94312501

GI number: 94312501

Start: 3873381

End: 3874313

Strand: Reverse

Name: yafC [H]

Synonym: Rmet_3570

Alternate gene names: 94312501

Gene position: 3874313-3873381 (Counterclockwise)

Preceding gene: 94312503

Following gene: 94312496

Centisome position: 98.63

GC content: 63.88

Gene sequence:

>933_bases
ATGGATCGGCTTCAATCGATGCGCGTCTTCGCCAAACTCGTCGAACTAGGCAGTTTTGCCCGTGCGGCGCAGCAATTGGA
AATGTCCAATGCGGTCGTGACGCGCTACGTCGCCGATCTGGAAAGCCATCTCGGCACCCGGTTGCTGAACCGGACCACCC
GAAGCCTCTCCCTGACCGACGCCGGCGAGACGTATCTGCAGCGCTGTTCGCAGATCCTCGAAGACGTGGAGGAAGCCGAG
TCGATCGTTGCCGCGCGCAGCCAGTCACTCTCCGGCACGCTACGGCTTGTCACCCCAGTCATGTTCGGCCTGCATCTGCT
GCCGCAGATCCTGGAACGCTTCCAGCAGCTGTATCCCGACGTCGTCTTCGACGTGCAGCTTTCGGACCGAATGATCGACA
TTGTCGAAGAAGGGCGGGACGTAGGCGTGATGCTGTCCGATCTCGGGCTCGGCTCGCACCTCGTGGCGCGCCCGCTGATC
TCCGCCGAAGTCATTCTTTGCGCCTCGCCGGGCTATCTGCGCGAACACCCGCCGCTGCGCAACGCGCATGACCTGTCCAA
CCACCGCGCCATCGCGATGCGGCTGCCCAACGCCGAGCACGAATGGACGTTGTCCGGCCCCGAAGGCGAGGTGACCGTAC
CGATTCGCCCGGGCCTGCTGTGCAGCAATGCCGAACTGGCGCACCAGGCGGCGCTGACCAATATGGGCATCGCGATGCTG
TCGTCGTACCTGGCACGACCGAACATCGAGGCAGGGCGGCTGACGCATATCCTGCCCCAGTACCAGTTGCCGCGCCGCGA
CGTGAGCGTGGTCTATCCGAGCCGCAAGTTCCTGCCGACCAAGGTCCGGGCCTTCATCGACTTCCTGCTGGAGGAAAGCC
AGCAGCGGGCGGTGGACACGGAGAACAAGCCGCAGATGACCGCGGCAAAGTGA

Upstream 100 bases:

>100_bases
GATATGAATAAATAGCGCCGTCCACAATGATTGGTTGTGCTTTCAACAATAAATCACCCGGATCGTGTAAAAATTCACCG
GTGAACAGGGAGACTATGTC

Downstream 100 bases:

>100_bases
AAACGGCGGGGCTCGCGCCCCGCCGTTTTACCTTCCCGTGATGCCAGAAGGTAAGTGATTACTCTTCGGCTTCGGCCGTC
TGCTTTGTGGTTGCGCGCGT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MDRLQSMRVFAKLVELGSFARAAQQLEMSNAVVTRYVADLESHLGTRLLNRTTRSLSLTDAGETYLQRCSQILEDVEEAE
SIVAARSQSLSGTLRLVTPVMFGLHLLPQILERFQQLYPDVVFDVQLSDRMIDIVEEGRDVGVMLSDLGLGSHLVARPLI
SAEVILCASPGYLREHPPLRNAHDLSNHRAIAMRLPNAEHEWTLSGPEGEVTVPIRPGLLCSNAELAHQAALTNMGIAML
SSYLARPNIEAGRLTHILPQYQLPRRDVSVVYPSRKFLPTKVRAFIDFLLEESQQRAVDTENKPQMTAAK

Sequences:

>Translated_310_residues
MDRLQSMRVFAKLVELGSFARAAQQLEMSNAVVTRYVADLESHLGTRLLNRTTRSLSLTDAGETYLQRCSQILEDVEEAE
SIVAARSQSLSGTLRLVTPVMFGLHLLPQILERFQQLYPDVVFDVQLSDRMIDIVEEGRDVGVMLSDLGLGSHLVARPLI
SAEVILCASPGYLREHPPLRNAHDLSNHRAIAMRLPNAEHEWTLSGPEGEVTVPIRPGLLCSNAELAHQAALTNMGIAML
SSYLARPNIEAGRLTHILPQYQLPRRDVSVVYPSRKFLPTKVRAFIDFLLEESQQRAVDTENKPQMTAAK
>Mature_310_residues
MDRLQSMRVFAKLVELGSFARAAQQLEMSNAVVTRYVADLESHLGTRLLNRTTRSLSLTDAGETYLQRCSQILEDVEEAE
SIVAARSQSLSGTLRLVTPVMFGLHLLPQILERFQQLYPDVVFDVQLSDRMIDIVEEGRDVGVMLSDLGLGSHLVARPLI
SAEVILCASPGYLREHPPLRNAHDLSNHRAIAMRLPNAEHEWTLSGPEGEVTVPIRPGLLCSNAELAHQAALTNMGIAML
SSYLARPNIEAGRLTHILPQYQLPRRDVSVVYPSRKFLPTKVRAFIDFLLEESQQRAVDTENKPQMTAAK

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=290, Percent_Identity=35.5172413793103, Blast_Score=164, Evalue=7e-42,
Organism=Escherichia coli, GI87081978, Length=289, Percent_Identity=31.4878892733564, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI145693193, Length=302, Percent_Identity=32.4503311258278, Blast_Score=137, Evalue=7e-34,
Organism=Escherichia coli, GI1789639, Length=292, Percent_Identity=32.1917808219178, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1789440, Length=294, Percent_Identity=28.9115646258503, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1787128, Length=295, Percent_Identity=27.1186440677966, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1789173, Length=253, Percent_Identity=29.2490118577075, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1787589, Length=290, Percent_Identity=26.551724137931, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788706, Length=302, Percent_Identity=25.1655629139073, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790011, Length=319, Percent_Identity=22.257053291536, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788748, Length=120, Percent_Identity=34.1666666666667, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787601, Length=212, Percent_Identity=24.5283018867925, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1788481, Length=305, Percent_Identity=23.6065573770492, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI157672245, Length=184, Percent_Identity=26.6304347826087, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI145693105, Length=198, Percent_Identity=24.2424242424242, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1789506, Length=173, Percent_Identity=23.121387283237, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786448, Length=302, Percent_Identity=23.841059602649, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1787879, Length=145, Percent_Identity=30.3448275862069, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34543; Mature: 34543

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRLQSMRVFAKLVELGSFARAAQQLEMSNAVVTRYVADLESHLGTRLLNRTTRSLSLTD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEECCC
AGETYLQRCSQILEDVEEAESIVAARSQSLSGTLRLVTPVMFGLHLLPQILERFQQLYPD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VVFDVQLSDRMIDIVEEGRDVGVMLSDLGLGSHLVARPLISAEVILCASPGYLREHPPLR
EEEEEEHHHHHHHHHHCCCCCEEEHHHCCCCHHHHHHHHHHHEEEEECCCCCCCCCCCCC
NAHDLSNHRAIAMRLPNAEHEWTLSGPEGEVTVPIRPGLLCSNAELAHQAALTNMGIAML
CCCCCCCCCEEEEECCCCCCCEEEECCCCCEEEEECCCEEECCHHHHHHHHHHHHHHHHH
SSYLARPNIEAGRLTHILPQYQLPRRDVSVVYPSRKFLPTKVRAFIDFLLEESQQRAVDT
HHHHHCCCCCCCHHHHHCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCC
ENKPQMTAAK
CCCCCCCCCC
>Mature Secondary Structure
MDRLQSMRVFAKLVELGSFARAAQQLEMSNAVVTRYVADLESHLGTRLLNRTTRSLSLTD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEECCC
AGETYLQRCSQILEDVEEAESIVAARSQSLSGTLRLVTPVMFGLHLLPQILERFQQLYPD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VVFDVQLSDRMIDIVEEGRDVGVMLSDLGLGSHLVARPLISAEVILCASPGYLREHPPLR
EEEEEEHHHHHHHHHHCCCCCEEEHHHCCCCHHHHHHHHHHHEEEEECCCCCCCCCCCCC
NAHDLSNHRAIAMRLPNAEHEWTLSGPEGEVTVPIRPGLLCSNAELAHQAALTNMGIAML
CCCCCCCCCEEEEECCCCCCCEEEECCCCCEEEEECCCEEECCHHHHHHHHHHHHHHHHH
SSYLARPNIEAGRLTHILPQYQLPRRDVSVVYPSRKFLPTKVRAFIDFLLEESQQRAVDT
HHHHHCCCCCCCHHHHHCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCC
ENKPQMTAAK
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]