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The map label for this gene is livH [H]

Identifier: 94312443

GI number: 94312443

Start: 3802744

End: 3803796

Strand: Reverse

Name: livH [H]

Synonym: Rmet_3512

Alternate gene names: 94312443

Gene position: 3803796-3802744 (Counterclockwise)

Preceding gene: 94312444

Following gene: 94312442

Centisome position: 96.84

GC content: 63.91

Gene sequence:

>1053_bases
ATGGACCTATCGATTGCGGCCATTCTGGCGCAGGACGGCATCACCTCCGGCGCGATCTACGCGCTGCTGGCACTGGCGCT
GGTGCTGGTGTTCTCGGTGACGCGCGTCATCTTCATCCCCCAGGGCGAGTTTGTTGCATACGGCGCGCTGACGCTTGCAG
CGATGCAGGCCGGCCATGCACCCAAGACGACGTGGCTGTTGCTCACGATGGGCGTGCTGACATTTCTCTATGAGTGCGTG
ACCGTGATGCGCAGCCCCGAGTTGCGCAGTACCGCGCCGCGGAGGTTGGCGATTCTCGCGGGCAAGTACCTGCTGTTTCC
GGGTGCCGTGCATCTGGTGGTGCAGCAGTACGGTGGTCAACCCTTGCCGATGCTCGCGCAGATCGCGCTGACGCTGCTCG
TTGTGATTCCGCTCGGACCGATGCTGTATCGGCTCGCGTACCAGCCCTTGGCGGAGGCGAGCACGCTGGTGCTGCTGATC
GTATCCGTTGGGGTGCATTTCGCACTGGTGGGCTTGGGGCTCGTGATGTTCGGCGCGGAAGGGTCGCGCACGACGGCGTT
CTCCGATGCGCGCTTCGAAGTTGGCAGTCTCACCATATCGGGGCAAAGCCTCTGGGTCGTGGCGGTGTCGGCATTGCTGA
TTGGCGCGCTCTGGTTCTATTTCGATCGCACGCTGCAGGGCAAGGCATTGCGTGCCACGGCGGTGAACCGGCTTGGCGCG
CGTCTGGTCGGCATCGGTACCACGCAGGCGGGCCGCCTGTCGTTCACGCTGGCTGCGGCGATGGGCGCGCTGTGCGGCAT
CCTGATCGCGCCGCTGACGACGATCTACTACGAGTCCGGATTCCTGGTTGGTCTCAAGGGCTTCGTTGGAGCGATCGTCG
GCGGTCTTGTCAGCTATCCGGTGGCCGCGCTTGGCGCGCTGCTGGTGGGGCTGCTTGAATCGTATTCGTCGTTCTGGGCC
AGCGCGTTCAAGGAGGTGATCGTCTTCACGCTGATCCTTCCGGTGCTGTTGTGGCGCTCGCTCACGAGCCGGCATGTCGA
GGAAGAGGAGTAA

Upstream 100 bases:

>100_bases
ACCTCCGCATCCGGGCGGCCACGTTTGACGGCAGTGGAGGCAGCAGAGGGAATCGCGTTGCCTTGCTTCATCCATGACAA
CGAGTAGACACGAGTAGACA

Downstream 100 bases:

>100_bases
GCCATGACGATGCTCACCGACAAGCAGATGGAGAAGGACATGGGTTCGCGTGAAGCGCCGGCAGTTCGCGGCACGGGCGC
ATTGCGCAATCGCATTGCGA

Product: ABC transporter permease

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: LIV-I protein H [H]

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MDLSIAAILAQDGITSGAIYALLALALVLVFSVTRVIFIPQGEFVAYGALTLAAMQAGHAPKTTWLLLTMGVLTFLYECV
TVMRSPELRSTAPRRLAILAGKYLLFPGAVHLVVQQYGGQPLPMLAQIALTLLVVIPLGPMLYRLAYQPLAEASTLVLLI
VSVGVHFALVGLGLVMFGAEGSRTTAFSDARFEVGSLTISGQSLWVVAVSALLIGALWFYFDRTLQGKALRATAVNRLGA
RLVGIGTTQAGRLSFTLAAAMGALCGILIAPLTTIYYESGFLVGLKGFVGAIVGGLVSYPVAALGALLVGLLESYSSFWA
SAFKEVIVFTLILPVLLWRSLTSRHVEEEE

Sequences:

>Translated_350_residues
MDLSIAAILAQDGITSGAIYALLALALVLVFSVTRVIFIPQGEFVAYGALTLAAMQAGHAPKTTWLLLTMGVLTFLYECV
TVMRSPELRSTAPRRLAILAGKYLLFPGAVHLVVQQYGGQPLPMLAQIALTLLVVIPLGPMLYRLAYQPLAEASTLVLLI
VSVGVHFALVGLGLVMFGAEGSRTTAFSDARFEVGSLTISGQSLWVVAVSALLIGALWFYFDRTLQGKALRATAVNRLGA
RLVGIGTTQAGRLSFTLAAAMGALCGILIAPLTTIYYESGFLVGLKGFVGAIVGGLVSYPVAALGALLVGLLESYSSFWA
SAFKEVIVFTLILPVLLWRSLTSRHVEEEE
>Mature_350_residues
MDLSIAAILAQDGITSGAIYALLALALVLVFSVTRVIFIPQGEFVAYGALTLAAMQAGHAPKTTWLLLTMGVLTFLYECV
TVMRSPELRSTAPRRLAILAGKYLLFPGAVHLVVQQYGGQPLPMLAQIALTLLVVIPLGPMLYRLAYQPLAEASTLVLLI
VSVGVHFALVGLGLVMFGAEGSRTTAFSDARFEVGSLTISGQSLWVVAVSALLIGALWFYFDRTLQGKALRATAVNRLGA
RLVGIGTTQAGRLSFTLAAAMGALCGILIAPLTTIYYESGFLVGLKGFVGAIVGGLVSYPVAALGALLVGLLESYSSFWA
SAFKEVIVFTLILPVLLWRSLTSRHVEEEE

Specific function: Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane [H]

COG id: COG0559

COG function: function code E; Branched-chain amino acid ABC-type transport system, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789866, Length=209, Percent_Identity=32.5358851674641, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 37138; Mature: 37138

Theoretical pI: Translated: 8.94; Mature: 8.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLSIAAILAQDGITSGAIYALLALALVLVFSVTRVIFIPQGEFVAYGALTLAAMQAGHA
CCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHCCCC
PKTTWLLLTMGVLTFLYECVTVMRSPELRSTAPRRLAILAGKYLLFPGAVHLVVQQYGGQ
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCC
PLPMLAQIALTLLVVIPLGPMLYRLAYQPLAEASTLVLLIVSVGVHFALVGLGLVMFGAE
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GSRTTAFSDARFEVGSLTISGQSLWVVAVSALLIGALWFYFDRTLQGKALRATAVNRLGA
CCCCCEECCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCC
RLVGIGTTQAGRLSFTLAAAMGALCGILIAPLTTIYYESGFLVGLKGFVGAIVGGLVSYP
CEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHH
VAALGALLVGLLESYSSFWASAFKEVIVFTLILPVLLWRSLTSRHVEEEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MDLSIAAILAQDGITSGAIYALLALALVLVFSVTRVIFIPQGEFVAYGALTLAAMQAGHA
CCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHCCCC
PKTTWLLLTMGVLTFLYECVTVMRSPELRSTAPRRLAILAGKYLLFPGAVHLVVQQYGGQ
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCC
PLPMLAQIALTLLVVIPLGPMLYRLAYQPLAEASTLVLLIVSVGVHFALVGLGLVMFGAE
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GSRTTAFSDARFEVGSLTISGQSLWVVAVSALLIGALWFYFDRTLQGKALRATAVNRLGA
CCCCCEECCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCC
RLVGIGTTQAGRLSFTLAAAMGALCGILIAPLTTIYYESGFLVGLKGFVGAIVGGLVSYP
CEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHH
VAALGALLVGLLESYSSFWASAFKEVIVFTLILPVLLWRSLTSRHVEEEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]