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The map label for this gene is speH [H]

Identifier: 94312388

GI number: 94312388

Start: 3733447

End: 3733833

Strand: Reverse

Name: speH [H]

Synonym: Rmet_3457

Alternate gene names: 94312388

Gene position: 3733833-3733447 (Counterclockwise)

Preceding gene: 94312389

Following gene: 94312387

Centisome position: 95.05

GC content: 66.93

Gene sequence:

>387_bases
ATGAATGCACCGACGCTTGCCTGCCCACCGGTTCTTGGCCGCCACCTGCTGCTCGACATGCAGGGCGTGACCGCCGCACG
GCTCACCGATGCCGTGCTGATCGAGCGCGTGCTTTACGATGCCGCCCGCGTGTCAGGCGCCACGCCGGTGGATGCGCGGT
TCCAGCATTTCGGCCCCGGTCTCGGTGTCACGGGCGTGCTGCTGCTCAAGGAATCGCACATCAGCATCCATACCTGGCCG
GAATATGGTTTCGCGGCTGTGGATATCTTCATGTGCGGTGCGGCGCAGCCCCACCGGGGCATCGAAGCCATCGTGGCCGA
ACTGGCGCCGGCGCAATGGCATGTGCGCGATGCAGCGCGTGGCCCCGCCTCTGCAGGGTCCGCCTGA

Upstream 100 bases:

>100_bases
GTCGTCGGCTCGCGGCTGGAGTGGCTCCGGCGGATACGGCGGTTCGGGCGGCGGCTGGTCTTCGGGCGCCGGTCACAAGT
AGTCCGGTGAGACGATCGCC

Downstream 100 bases:

>100_bases
TTGGGCTACACTTCACCGGTAACCCTGTAATTACTACAGGGATCTGGCATCGTGGAGGCACTGACCATGCGTATCGGCGA
ACTGTCCCGCCACAGTGGCT

Product: S-adenosylmethionine decarboxylase

Products: NA

Alternate protein names: AdoMetDC; SAMDC [H]

Number of amino acids: Translated: 128; Mature: 128

Protein sequence:

>128_residues
MNAPTLACPPVLGRHLLLDMQGVTAARLTDAVLIERVLYDAARVSGATPVDARFQHFGPGLGVTGVLLLKESHISIHTWP
EYGFAAVDIFMCGAAQPHRGIEAIVAELAPAQWHVRDAARGPASAGSA

Sequences:

>Translated_128_residues
MNAPTLACPPVLGRHLLLDMQGVTAARLTDAVLIERVLYDAARVSGATPVDARFQHFGPGLGVTGVLLLKESHISIHTWP
EYGFAAVDIFMCGAAQPHRGIEAIVAELAPAQWHVRDAARGPASAGSA
>Mature_128_residues
MNAPTLACPPVLGRHLLLDMQGVTAARLTDAVLIERVLYDAARVSGATPVDARFQHFGPGLGVTGVLLLKESHISIHTWP
EYGFAAVDIFMCGAAQPHRGIEAIVAELAPAQWHVRDAARGPASAGSA

Specific function: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine [H]

COG id: COG1586

COG function: function code E; S-adenosylmethionine decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003826
- InterPro:   IPR016067
- InterPro:   IPR017716 [H]

Pfam domain/function: PF02675 AdoMet_dc [H]

EC number: =4.1.1.50 [H]

Molecular weight: Translated: 13474; Mature: 13474

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAPTLACPPVLGRHLLLDMQGVTAARLTDAVLIERVLYDAARVSGATPVDARFQHFGPG
CCCCCCCCCHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCC
LGVTGVLLLKESHISIHTWPEYGFAAVDIFMCGAAQPHRGIEAIVAELAPAQWHVRDAAR
CCCEEEEEEECCCCEEEECCCCCHHHHHHHHCCCCCCCCCHHHHHHHHCCCCEEHHHHCC
GPASAGSA
CCCCCCCC
>Mature Secondary Structure
MNAPTLACPPVLGRHLLLDMQGVTAARLTDAVLIERVLYDAARVSGATPVDARFQHFGPG
CCCCCCCCCHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCC
LGVTGVLLLKESHISIHTWPEYGFAAVDIFMCGAAQPHRGIEAIVAELAPAQWHVRDAAR
CCCEEEEEEECCCCEEEECCCCCHHHHHHHHCCCCCCCCCHHHHHHHHCCCCEEHHHHCC
GPASAGSA
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087; 11073910 [H]