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The map label for this gene is pbrR3 [H]

Identifier: 94312387

GI number: 94312387

Start: 3732946

End: 3733395

Strand: Reverse

Name: pbrR3 [H]

Synonym: Rmet_3456

Alternate gene names: 94312387

Gene position: 3733395-3732946 (Counterclockwise)

Preceding gene: 94312388

Following gene: 335055670

Centisome position: 95.04

GC content: 64.67

Gene sequence:

>450_bases
GTGGAGGCACTGACCATGCGTATCGGCGAACTGTCCCGCCACAGTGGCTGCGACATCGAAACCATCCGCTATTACGAACG
TGAAGGGCTGCTGGACGCACCGCAGCGCGAGGACAACGGCTATCGCCGCTATGGCGACGGGCACCTCGTCCAGCTCAACT
TCGTGCGCCACTGCCGCTCGCTGGGCATGAGCCTGGCCGACGTGCGCAAGCTGCGCGACTTCCAGCGCAATCCGTCACTC
GCGTGCGACGACATCAATACGCTGTTGGACCGCCAGATCGAGCAGATCCACGCCCAGCGTGTTTCGCTGGAAGCGCTGGA
AGGTCAGTTGCGCACGCTGCGCCATACCTGCGAGAACCCAAATCCGCATCCGGCCAGCGAGTGCGGCATCCTGCAGAACC
TGCAGCAGGCAGCCGAGGGCGCGGCCTGCGAGTGCCACCCACGACACTAG

Upstream 100 bases:

>100_bases
GCATGTGCGCGATGCAGCGCGTGGCCCCGCCTCTGCAGGGTCCGCCTGATTGGGCTACACTTCACCGGTAACCCTGTAAT
TACTACAGGGATCTGGCATC

Downstream 100 bases:

>100_bases
GGATGCAGCGGGACGGCATCGTCACGCCGATCTCGCGACATCTCGCAACAAGGCGGGCGGCAAGCCGGAACAGGGGCATT
CCGCCCCCTCGCCTCGAATC

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MEALTMRIGELSRHSGCDIETIRYYEREGLLDAPQREDNGYRRYGDGHLVQLNFVRHCRSLGMSLADVRKLRDFQRNPSL
ACDDINTLLDRQIEQIHAQRVSLEALEGQLRTLRHTCENPNPHPASECGILQNLQQAAEGAACECHPRH

Sequences:

>Translated_149_residues
MEALTMRIGELSRHSGCDIETIRYYEREGLLDAPQREDNGYRRYGDGHLVQLNFVRHCRSLGMSLADVRKLRDFQRNPSL
ACDDINTLLDRQIEQIHAQRVSLEALEGQLRTLRHTCENPNPHPASECGILQNLQQAAEGAACECHPRH
>Mature_149_residues
MEALTMRIGELSRHSGCDIETIRYYEREGLLDAPQREDNGYRRYGDGHLVQLNFVRHCRSLGMSLADVRKLRDFQRNPSL
ACDDINTLLDRQIEQIHAQRVSLEALEGQLRTLRHTCENPNPHPASECGILQNLQQAAEGAACECHPRH

Specific function: Transcriptional regulator [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789687, Length=140, Percent_Identity=30.7142857142857, Blast_Score=82, Evalue=1e-17,
Organism=Escherichia coli, GI1786695, Length=129, Percent_Identity=27.906976744186, Blast_Score=69, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 17031; Mature: 17031

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
4.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEALTMRIGELSRHSGCDIETIRYYEREGLLDAPQREDNGYRRYGDGHLVQLNFVRHCRS
CCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCEECCCCCEEEHHHHHHHHH
LGMSLADVRKLRDFQRNPSLACDDINTLLDRQIEQIHAQRVSLEALEGQLRTLRHTCENP
HCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NPHPASECGILQNLQQAAEGAACECHPRH
CCCCHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MEALTMRIGELSRHSGCDIETIRYYEREGLLDAPQREDNGYRRYGDGHLVQLNFVRHCRS
CCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCEECCCCCEEEHHHHHHHHH
LGMSLADVRKLRDFQRNPSLACDDINTLLDRQIEQIHAQRVSLEALEGQLRTLRHTCENP
HCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NPHPASECGILQNLQQAAEGAACECHPRH
CCCCHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]