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The map label for this gene is murA [H]

Identifier: 94312181

GI number: 94312181

Start: 3522096

End: 3523346

Strand: Reverse

Name: murA [H]

Synonym: Rmet_3250

Alternate gene names: 94312181

Gene position: 3523346-3522096 (Counterclockwise)

Preceding gene: 94312182

Following gene: 94312180

Centisome position: 89.7

GC content: 65.95

Gene sequence:

>1251_bases
ATGGACAAATTCCAGATCCAGGGCAATGGGCCGCTCAAGGGCGAAATCCGCATCTCGGGCGCCAAGAACGCTGCGCTGCC
GATCCTGTGCGCCGGCCTGCTGACCGCCGATACGGTGACCATCGGCAACGTTCCCGACCTGCAGGACACGCGCACCATGC
TCAAGCTGCTGCGCCAGATGGGCATGAAGGCCGAGATGGTCGACGGCGTCGCCACGTTGCAGGGCGCCGACATCAACTCG
CCCGAAGCGTCGTACGACCTCGTGAAGACGATGCGCGCGTCGATTCTCGTGCTCGGGCCGCTGGTGGCGCGCTTTGGCGA
GGCACGTGTATCGCTGCCCGGTGGTTGCGGCATTGGCGCGCGTCCGGTGGACCAGCACATCAAGGGCCTGCAAGCGATGG
GCGCCGAGATCACCATCGAGCACGGCTTCATTCATGCCCGCGCCAATCGTCTGAAGGGCGCTCGCGTGGTCACGGACATG
ATCACCGTGACCGGCACCGAGAATCTGCTGATGGCAGCCACGCTGGCCGAAGGCGAGACCGTGCTTGAAAACGCCGCGCG
CGAGCCCGAGGTCACCGACCTGGCCGAACTGCTGGTGAAGATGGGCGCCAAGATCGAAGGCATCGGTACTGACCGCCTGG
TGGTGCAGGGCGTGGATCGCCTGCACGGCGCCGAGCACAAGGTAGTGGCCGACCGCATCGAGGCGGGCACGTTCCTGTGC
GCCGCAGCGGCCACGCTTGGCGACATCGTGCTGCGCGGCATCCCGCCGCTGATTCTCGACGCTGTGCTGATCAAGCTGCG
CGAAGCCGGCGCTACCGTGGAAACCGGTGATGACTGGATTCGCCTGGCCATGCCGCAGCGCGCGCAGGCCGTGAGCTTCC
GCACCTCCGAATACCCGGCGTTCCCGACCGACATGCAGGCGCAATTCATGGCGCTCAATGCCGTCGCCGAGGGTACCGCG
CGTATCACCGAGACGATCTTCGAGAACCGCTTCATGCACGTGCAGGAACTGAACCGCCTGGGCGCCAACATCACCGCCGA
AGGCAATACGGCCGTGGTGACCGGTGTGCCGCGACTGTCCGGCGCCAGCGTGATGGCCACCGACCTGCGCGCGTCGGCCA
GTCTCGTGATCGCGGGTCTGGTGGCGGATGGCGAGACGGTGATCGACCGCATCTACCACCTGGATCGTGGGTACGACCGC
ATGGAAAACAAGCTGTCCGCGGTCGGCGCGAAGATCCTCCGCATCAGCTGA

Upstream 100 bases:

>100_bases
CCCCCGCCGAATGGCAGGCTGGCGGCAAGTAAGCGGCGTTCCGCACCACAGAACAACTTTGCCGGCTGGGCGTGTGCCCG
GCTGGGACTACTGACAGAAC

Downstream 100 bases:

>100_bases
GGCACGACGCCCGCCACGAACGATGCCGAAACGGCAAGCCGCCCCCGAACACTGCTGAAGAATCTACGATGAGCCCCGCT
TTCAATGCTTCGCCCGACCA

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MDKFQIQGNGPLKGEIRISGAKNAALPILCAGLLTADTVTIGNVPDLQDTRTMLKLLRQMGMKAEMVDGVATLQGADINS
PEASYDLVKTMRASILVLGPLVARFGEARVSLPGGCGIGARPVDQHIKGLQAMGAEITIEHGFIHARANRLKGARVVTDM
ITVTGTENLLMAATLAEGETVLENAAREPEVTDLAELLVKMGAKIEGIGTDRLVVQGVDRLHGAEHKVVADRIEAGTFLC
AAAATLGDIVLRGIPPLILDAVLIKLREAGATVETGDDWIRLAMPQRAQAVSFRTSEYPAFPTDMQAQFMALNAVAEGTA
RITETIFENRFMHVQELNRLGANITAEGNTAVVTGVPRLSGASVMATDLRASASLVIAGLVADGETVIDRIYHLDRGYDR
MENKLSAVGAKILRIS

Sequences:

>Translated_416_residues
MDKFQIQGNGPLKGEIRISGAKNAALPILCAGLLTADTVTIGNVPDLQDTRTMLKLLRQMGMKAEMVDGVATLQGADINS
PEASYDLVKTMRASILVLGPLVARFGEARVSLPGGCGIGARPVDQHIKGLQAMGAEITIEHGFIHARANRLKGARVVTDM
ITVTGTENLLMAATLAEGETVLENAAREPEVTDLAELLVKMGAKIEGIGTDRLVVQGVDRLHGAEHKVVADRIEAGTFLC
AAAATLGDIVLRGIPPLILDAVLIKLREAGATVETGDDWIRLAMPQRAQAVSFRTSEYPAFPTDMQAQFMALNAVAEGTA
RITETIFENRFMHVQELNRLGANITAEGNTAVVTGVPRLSGASVMATDLRASASLVIAGLVADGETVIDRIYHLDRGYDR
MENKLSAVGAKILRIS
>Mature_416_residues
MDKFQIQGNGPLKGEIRISGAKNAALPILCAGLLTADTVTIGNVPDLQDTRTMLKLLRQMGMKAEMVDGVATLQGADINS
PEASYDLVKTMRASILVLGPLVARFGEARVSLPGGCGIGARPVDQHIKGLQAMGAEITIEHGFIHARANRLKGARVVTDM
ITVTGTENLLMAATLAEGETVLENAAREPEVTDLAELLVKMGAKIEGIGTDRLVVQGVDRLHGAEHKVVADRIEAGTFLC
AAAATLGDIVLRGIPPLILDAVLIKLREAGATVETGDDWIRLAMPQRAQAVSFRTSEYPAFPTDMQAQFMALNAVAEGTA
RITETIFENRFMHVQELNRLGANITAEGNTAVVTGVPRLSGASVMATDLRASASLVIAGLVADGETVIDRIYHLDRGYDR
MENKLSAVGAKILRIS

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=418, Percent_Identity=59.8086124401914, Blast_Score=491, Evalue=1e-140,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 44219; Mature: 44219

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKFQIQGNGPLKGEIRISGAKNAALPILCAGLLTADTVTIGNVPDLQDTRTMLKLLRQM
CCCEEECCCCCCEEEEEECCCCCCCHHHHHHHHHHHCEEEECCCCCCHHHHHHHHHHHHH
GMKAEMVDGVATLQGADINSPEASYDLVKTMRASILVLGPLVARFGEARVSLPGGCGIGA
CCCHHHHCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCC
RPVDQHIKGLQAMGAEITIEHGFIHARANRLKGARVVTDMITVTGTENLLMAATLAEGET
CCHHHHHHHHHHCCCEEEEECCEEEEHHHHCCCCEEEEHHEEECCCCCEEEEEECCCCHH
VLENAAREPEVTDLAELLVKMGAKIEGIGTDRLVVQGVDRLHGAEHKVVADRIEAGTFLC
HHHHCCCCCCHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHCCHHHH
AAAATLGDIVLRGIPPLILDAVLIKLREAGATVETGDDWIRLAMPQRAQAVSFRTSEYPA
HHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEECCCCEEEEECCCCHHHEEEECCCCCC
FPTDMQAQFMALNAVAEGTARITETIFENRFMHVQELNRLGANITAEGNTAVVTGVPRLS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEECCCEEEEECCCCCC
GASVMATDLRASASLVIAGLVADGETVIDRIYHLDRGYDRMENKLSAVGAKILRIS
CCEEEEHHHHCCCEEEEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHCCEEEEEC
>Mature Secondary Structure
MDKFQIQGNGPLKGEIRISGAKNAALPILCAGLLTADTVTIGNVPDLQDTRTMLKLLRQM
CCCEEECCCCCCEEEEEECCCCCCCHHHHHHHHHHHCEEEECCCCCCHHHHHHHHHHHHH
GMKAEMVDGVATLQGADINSPEASYDLVKTMRASILVLGPLVARFGEARVSLPGGCGIGA
CCCHHHHCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCC
RPVDQHIKGLQAMGAEITIEHGFIHARANRLKGARVVTDMITVTGTENLLMAATLAEGET
CCHHHHHHHHHHCCCEEEEECCEEEEHHHHCCCCEEEEHHEEECCCCCEEEEEECCCCHH
VLENAAREPEVTDLAELLVKMGAKIEGIGTDRLVVQGVDRLHGAEHKVVADRIEAGTFLC
HHHHCCCCCCHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHCCHHHH
AAAATLGDIVLRGIPPLILDAVLIKLREAGATVETGDDWIRLAMPQRAQAVSFRTSEYPA
HHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEECCCCEEEEECCCCHHHEEEECCCCCC
FPTDMQAQFMALNAVAEGTARITETIFENRFMHVQELNRLGANITAEGNTAVVTGVPRLS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEECCCEEEEECCCCCC
GASVMATDLRASASLVIAGLVADGETVIDRIYHLDRGYDRMENKLSAVGAKILRIS
CCEEEEHHHHCCCEEEEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA