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The map label for this gene is ftsW [H]

Identifier: 94312060

GI number: 94312060

Start: 3391673

End: 3392914

Strand: Reverse

Name: ftsW [H]

Synonym: Rmet_3129

Alternate gene names: 94312060

Gene position: 3392914-3391673 (Counterclockwise)

Preceding gene: 94312061

Following gene: 94312059

Centisome position: 86.38

GC content: 63.45

Gene sequence:

>1242_bases
ATGAGCGACTCGCAGGTCAAGCGCAGCGGATTCATCGGCGCCACCATCGGCAATGCCTGGGGTGGCCTGCGTGATGCGGT
GTCCGGCGTCAAGCCGACACGCTCCCGCATGATGGAGTACGACCAGCCCCTGCTGTGGGTAGCGATCGTACTGCTGACGT
TCGGCCTGGTGATGGTCTACTCGGCATCGATCGCGCTGCCGGACTCGCCGCGCTACGCCAACTACCGCGAGGCCCATTTC
CTGGTGCGCCATGCGTTCAGCCTGGTGATCGGACTCTCCACGGCGCTGGTGGCGTTCCAGATTCCGGTGAAGGTCTGGGA
CCGCTACGCGCCGAAGCTGTTCATCGTCGCGCTGATCCTGCTGGTGATCGTGCTGGTGCCGTTCGTCGGCAAGGGCGTGA
ACGGCGCGCGGCGCTGGATTCCGCTTGGCCTGATGAATTTCCAGCCGTCCGAACTGATGAAGCTGGCCGTGGTGCTGTAC
GCGGCCAACTACACGGTGCGCAAGCAGGAGTGGATGCAGACCGTCTCGAAGGGCTTCCTCCCGATGGGGGTGGCCGTGGT
CGTGGTGGGGATGCTGCTACTGCTCGAACCCGATATGGGCGCGTTCCTGGTGATCGCGGCCGTGGCGATGGGCATCCTGT
TTCTGGGTGGCATCAACGGCAAGCTGTTCGCCGGCCTGGTCGGCGTGGCCGTGGGTGCGTTCGCGCTGCTGATTACGGCA
TCGCCATGGCGTCGCGAGCGGATCTTTGCGTACCTGAACCCGTGGGAAGAAAGTAACGCGCTCGGCAAGGCTTATCAGCT
CACACACTCGCTGATCGCCTTCGGCCGTGGCGAATGGACCGGCGTGGGCCTGGGCGGCAGCATCGAGAAGTTGCACTACC
TGCCGGAAGCCCACACTGACTTCATCCTGGCGGTGATCGGCGAGGAATTCGGCTTCATCGGTGTGCTGGTGATGATCGTG
CTGTTCTACTGGATGGTCCGCCGCTGCTTCGACATCGGCCGTACGGCGCTGCAGCTCGACCGTACCTTCGCCGGTCTGGT
GGCCAAGGGCATGGGCATCTGGATCGGCTGGCAAACGTTCATCAACATGGGCGTGAACCTGGGCCTGCTGCCGACCAAGG
GCCTGACGCTGCCACTGGTCAGCTATGGCGGCTCGGGCATCCTGATGAACTGTGTGGCGTTGGCGATTGTCCTGCGCATT
GACTACGAGAACAGGGTGTTGATGCGCGGAGGGAAGGTATGA

Upstream 100 bases:

>100_bases
CGGCTTGCGCCAGCCTCGACATGTTCCGTAACTACGTGCATCGCGCCCAGGTGTTCCGCGGCGCGGTGGAAGAACTGGCT
TTGTCCCGGGGGATCATGCC

Downstream 100 bases:

>100_bases
CCGCACGCACGCTGCTCGTGATGGCTGGCGGCACCGGGGGCCACGTGTTCCCGGGGCTGGCGGTCGCGCGTGCGTTGCGT
GACGAGGGCTGGCGCGTGGT

Product: integral membrane protein involved in stabilizing FstZ ring during cell division

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 412

Protein sequence:

>413_residues
MSDSQVKRSGFIGATIGNAWGGLRDAVSGVKPTRSRMMEYDQPLLWVAIVLLTFGLVMVYSASIALPDSPRYANYREAHF
LVRHAFSLVIGLSTALVAFQIPVKVWDRYAPKLFIVALILLVIVLVPFVGKGVNGARRWIPLGLMNFQPSELMKLAVVLY
AANYTVRKQEWMQTVSKGFLPMGVAVVVVGMLLLLEPDMGAFLVIAAVAMGILFLGGINGKLFAGLVGVAVGAFALLITA
SPWRRERIFAYLNPWEESNALGKAYQLTHSLIAFGRGEWTGVGLGGSIEKLHYLPEAHTDFILAVIGEEFGFIGVLVMIV
LFYWMVRRCFDIGRTALQLDRTFAGLVAKGMGIWIGWQTFINMGVNLGLLPTKGLTLPLVSYGGSGILMNCVALAIVLRI
DYENRVLMRGGKV

Sequences:

>Translated_413_residues
MSDSQVKRSGFIGATIGNAWGGLRDAVSGVKPTRSRMMEYDQPLLWVAIVLLTFGLVMVYSASIALPDSPRYANYREAHF
LVRHAFSLVIGLSTALVAFQIPVKVWDRYAPKLFIVALILLVIVLVPFVGKGVNGARRWIPLGLMNFQPSELMKLAVVLY
AANYTVRKQEWMQTVSKGFLPMGVAVVVVGMLLLLEPDMGAFLVIAAVAMGILFLGGINGKLFAGLVGVAVGAFALLITA
SPWRRERIFAYLNPWEESNALGKAYQLTHSLIAFGRGEWTGVGLGGSIEKLHYLPEAHTDFILAVIGEEFGFIGVLVMIV
LFYWMVRRCFDIGRTALQLDRTFAGLVAKGMGIWIGWQTFINMGVNLGLLPTKGLTLPLVSYGGSGILMNCVALAIVLRI
DYENRVLMRGGKV
>Mature_412_residues
SDSQVKRSGFIGATIGNAWGGLRDAVSGVKPTRSRMMEYDQPLLWVAIVLLTFGLVMVYSASIALPDSPRYANYREAHFL
VRHAFSLVIGLSTALVAFQIPVKVWDRYAPKLFIVALILLVIVLVPFVGKGVNGARRWIPLGLMNFQPSELMKLAVVLYA
ANYTVRKQEWMQTVSKGFLPMGVAVVVVGMLLLLEPDMGAFLVIAAVAMGILFLGGINGKLFAGLVGVAVGAFALLITAS
PWRRERIFAYLNPWEESNALGKAYQLTHSLIAFGRGEWTGVGLGGSIEKLHYLPEAHTDFILAVIGEEFGFIGVLVMIVL
FYWMVRRCFDIGRTALQLDRTFAGLVAKGMGIWIGWQTFINMGVNLGLLPTKGLTLPLVSYGGSGILMNCVALAIVLRID
YENRVLMRGGKV

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=380, Percent_Identity=45.2631578947368, Blast_Score=308, Evalue=4e-85,
Organism=Escherichia coli, GI1786853, Length=344, Percent_Identity=34.3023255813954, Blast_Score=153, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 45190; Mature: 45058

Theoretical pI: Translated: 10.11; Mature: 10.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHCCCCCCEECCCCCEEEHHHCCCCHHHHHHHHHHHHHEECCCCEEECCCCCC
>Mature Secondary Structure 
SDSQVKRSGFIGATIGNAWGGLRDAVSGVKPTRSRMMEYDQPLLWVAIVLLTFGLVMVY
CCCHHHHCCCCEEEHHHHHCCHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
SASIALPDSPRYANYREAHFLVRHAFSLVIGLSTALVAFQIPVKVWDRYAPKLFIVALIL
HCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCHHHHHHHHHH
LVIVLVPFVGKGVNGARRWIPLGLMNFQPSELMKLAVVLYAANYTVRKQEWMQTVSKGFL
HHHHHHHHHCCCCCCHHHEEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCC
PMGVAVVVVGMLLLLEPDMGAFLVIAAVAMGILFLGGINGKLFAGLVGVAVGAFALLITA
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCC
SPWRRERIFAYLNPWEESNALGKAYQLTHSLIAFGRGEWTGVGLGGSIEKLHYLPEAHTD
CCCHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHCCCCCCHH
FILAVIGEEFGFIGVLVMIVLFYWMVRRCFDIGRTALQLDRTFAGLVAKGMGIWIGWQTF
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCHHEEEHHHH
INMGVNLGLLPTKGLTLPLVSYGGSGILMNCVALAIVLRIDYENRVLMRGGKV
HHCCCCCCEECCCCCEEEHHHCCCCHHHHHHHHHHHHHEECCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]