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The map label for this gene is murG

Identifier: 94312059

GI number: 94312059

Start: 3390606

End: 3391676

Strand: Reverse

Name: murG

Synonym: Rmet_3128

Alternate gene names: 94312059

Gene position: 3391676-3390606 (Counterclockwise)

Preceding gene: 94312060

Following gene: 94312058

Centisome position: 86.34

GC content: 67.41

Gene sequence:

>1071_bases
ATGACCGCACGCACGCTGCTCGTGATGGCTGGCGGCACCGGGGGCCACGTGTTCCCGGGGCTGGCGGTCGCGCGTGCGTT
GCGTGACGAGGGCTGGCGCGTGGTCTGGCTCGGCAATCGTACGGGCATGGAAGCGACGCTGGTGCCGAAGCACGACATTC
CGATGGAGTACATCCAGTTCGGTGGACTGCGTGGCAAGGGCCTGCTGACCAAGCTCCTGCTGCCGCTGAACCTGCTGCGC
GCGTTCTGGCAGAGCATCGGCGCGCTGCGTCGGGTGAAGCCGGACGTGGTGCTCGGCATGGGCGGCTATATCACCTTCCC
GGCAGGGATGATGGCGTCGCTGCTCGGGCGCCCGCTGGTGCTGCACGAACAGAATTCGATCGCTGGCCTGGCGAACAAGG
TGTTGGCGAAGGTCGCGGACCGCGTGCTCTGCGCGTTCCCGGACGCGTTGCCGAATAGCGAATGGACCGGCAATCCGGTG
CGTGCCGAACTGGCGCAGATTCCGGCGCCGGAGTCACGCTACGACCATCGCGCCGGCCCGCTGCACGTGCTTGTGGTGGG
TGGCAGCCTTGGCGCGGCCGCGCTCAACGACGTGGTGCCGAAGGCAATCGCGCTGCTGCCCGAGGGGCAGCGCCCGGTCG
TCAAGCATCAGGCCGGCGCGAAACAGATCGATACGCTGCGCGCGAACTACGCAGCAGCAGGAGTGGCCGGCGATACCGTG
CCATTCATCGACGACATGGCGGCGGCCTACGCCGACGCCGATCTGGTCATCTGCCGCGCAGGCGCGATGACGGTTTCCGA
AGTGGCGGCCGCCGGTGTGGCAGCGCTGTTCGTGCCGTTTCCGCATGCGGTGGACGATCACCAGACCACCAATGCGACGT
TCCTGTCGAAGCAGGGCGCTGCGTTGCTGGTGCAACAGAACGAACTGACCGCGGAAGGTCTGGCGAAGACGCTCGCCGGC
CTGTCGCGGACGCAATTGAAAGACATGGCGCGCGCTGCGCGTGGCCTGGCCAAACCGGAGGCAACCCGGCGCGTCGCCGA
GATCTGCAGCCAGTTGGCGGGTAAATCGTGA

Upstream 100 bases:

>100_bases
TCAGCTATGGCGGCTCGGGCATCCTGATGAACTGTGTGGCGTTGGCGATTGTCCTGCGCATTGACTACGAGAACAGGGTG
TTGATGCGCGGAGGGAAGGT

Downstream 100 bases:

>100_bases
AACGAATTCAATGAAGCATATTGTCAAGAACATCCACTTCGTAGGCATTGGCGGGGCCGGCATGAGCGGCATCGCCGAGG
TCCTGCTGAATCTGGGCTAC

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MTARTLLVMAGGTGGHVFPGLAVARALRDEGWRVVWLGNRTGMEATLVPKHDIPMEYIQFGGLRGKGLLTKLLLPLNLLR
AFWQSIGALRRVKPDVVLGMGGYITFPAGMMASLLGRPLVLHEQNSIAGLANKVLAKVADRVLCAFPDALPNSEWTGNPV
RAELAQIPAPESRYDHRAGPLHVLVVGGSLGAAALNDVVPKAIALLPEGQRPVVKHQAGAKQIDTLRANYAAAGVAGDTV
PFIDDMAAAYADADLVICRAGAMTVSEVAAAGVAALFVPFPHAVDDHQTTNATFLSKQGAALLVQQNELTAEGLAKTLAG
LSRTQLKDMARAARGLAKPEATRRVAEICSQLAGKS

Sequences:

>Translated_356_residues
MTARTLLVMAGGTGGHVFPGLAVARALRDEGWRVVWLGNRTGMEATLVPKHDIPMEYIQFGGLRGKGLLTKLLLPLNLLR
AFWQSIGALRRVKPDVVLGMGGYITFPAGMMASLLGRPLVLHEQNSIAGLANKVLAKVADRVLCAFPDALPNSEWTGNPV
RAELAQIPAPESRYDHRAGPLHVLVVGGSLGAAALNDVVPKAIALLPEGQRPVVKHQAGAKQIDTLRANYAAAGVAGDTV
PFIDDMAAAYADADLVICRAGAMTVSEVAAAGVAALFVPFPHAVDDHQTTNATFLSKQGAALLVQQNELTAEGLAKTLAG
LSRTQLKDMARAARGLAKPEATRRVAEICSQLAGKS
>Mature_355_residues
TARTLLVMAGGTGGHVFPGLAVARALRDEGWRVVWLGNRTGMEATLVPKHDIPMEYIQFGGLRGKGLLTKLLLPLNLLRA
FWQSIGALRRVKPDVVLGMGGYITFPAGMMASLLGRPLVLHEQNSIAGLANKVLAKVADRVLCAFPDALPNSEWTGNPVR
AELAQIPAPESRYDHRAGPLHVLVVGGSLGAAALNDVVPKAIALLPEGQRPVVKHQAGAKQIDTLRANYAAAGVAGDTVP
FIDDMAAAYADADLVICRAGAMTVSEVAAAGVAALFVPFPHAVDDHQTTNATFLSKQGAALLVQQNELTAEGLAKTLAGL
SRTQLKDMARAARGLAKPEATRRVAEICSQLAGKS

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=351, Percent_Identity=52.1367521367521, Blast_Score=335, Evalue=2e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_RALME (Q1LIM6)

Other databases:

- EMBL:   CP000352
- RefSeq:   YP_585269.1
- ProteinModelPortal:   Q1LIM6
- SMR:   Q1LIM6
- STRING:   Q1LIM6
- GeneID:   4039957
- GenomeReviews:   CP000352_GR
- KEGG:   rme:Rmet_3128
- eggNOG:   COG0707
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- PhylomeDB:   Q1LIM6
- ProtClustDB:   PRK00726
- BioCyc:   RMET266264:RMET_3128-MONOMER
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 37429; Mature: 37298

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTARTLLVMAGGTGGHVFPGLAVARALRDEGWRVVWLGNRTGMEATLVPKHDIPMEYIQF
CCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCEEEECCCCCCCHHHHHH
GGLRGKGLLTKLLLPLNLLRAFWQSIGALRRVKPDVVLGMGGYITFPAGMMASLLGRPLV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEECCHHHHHHHHCCCEE
LHEQNSIAGLANKVLAKVADRVLCAFPDALPNSEWTGNPVRAELAQIPAPESRYDHRAGP
EECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCC
LHVLVVGGSLGAAALNDVVPKAIALLPEGQRPVVKHQAGAKQIDTLRANYAAAGVAGDTV
EEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHCCCCCCCC
PFIDDMAAAYADADLVICRAGAMTVSEVAAAGVAALFVPFPHAVDDHQTTNATFLSKQGA
HHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHEECCCCCCCCCCCCCCEEEECCCC
ALLVQQNELTAEGLAKTLAGLSRTQLKDMARAARGLAKPEATRRVAEICSQLAGKS
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TARTLLVMAGGTGGHVFPGLAVARALRDEGWRVVWLGNRTGMEATLVPKHDIPMEYIQF
CCEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCEEEECCCCCCCHHHHHH
GGLRGKGLLTKLLLPLNLLRAFWQSIGALRRVKPDVVLGMGGYITFPAGMMASLLGRPLV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEECCHHHHHHHHCCCEE
LHEQNSIAGLANKVLAKVADRVLCAFPDALPNSEWTGNPVRAELAQIPAPESRYDHRAGP
EECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCC
LHVLVVGGSLGAAALNDVVPKAIALLPEGQRPVVKHQAGAKQIDTLRANYAAAGVAGDTV
EEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHCCCCCCCC
PFIDDMAAAYADADLVICRAGAMTVSEVAAAGVAALFVPFPHAVDDHQTTNATFLSKQGA
HHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHEECCCCCCCCCCCCCCEEEECCCC
ALLVQQNELTAEGLAKTLAGLSRTQLKDMARAARGLAKPEATRRVAEICSQLAGKS
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA