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The map label for this gene is obgE [H]

Identifier: 94312035

GI number: 94312035

Start: 3363475

End: 3364572

Strand: Reverse

Name: obgE [H]

Synonym: Rmet_3104

Alternate gene names: 94312035

Gene position: 3364572-3363475 (Counterclockwise)

Preceding gene: 94312036

Following gene: 94312034

Centisome position: 85.65

GC content: 63.75

Gene sequence:

>1098_bases
ATGAAGTTCATTGACGAAGCCCGTATCGAAGCGATCGCCGGCAATGGCGGCAACGGAAGCGCTTCGTTTCGGCGCGAGAA
ATTTGTGCCCTTCGGTGGCCCCGATGGCGGTGACGGCGGCCGTGGCGGCAGCGTGTTCGCACAGGCCGACCGCAACATCA
ATACGCTGATCGACTTTCGCTACGCCAAGAAGCACGTGGCGCGGAACGGCGAAAACGGCCGGGGCTCGGATTGCTACGGC
GCGGCGGGTGAAGATGTCACGTTGCGGATGCCGGTGGGCACGCTGATCTCCGACATGGACACCGGCGAAGTCATTGCCGA
CCTGACCGAGCACGGCCAGCTGGTCTGTCTGGCCGAAGGCGGCATGGGCGGCTGGGGCAACCTCCACTTCAAGTCGAGTA
CCAACCGCGCGCCGCGCCAGCAGGTCGACGGCAAGCCGGGCGAGCGCCGCATGCTCAAGCTCGAACTGAAGGTGCTGGCG
GACGTCGGTCTGCTCGGCATGCCCAACGCGGGCAAGTCGACGTTTATCTCGCACGTGTCGAATGCACGTCCGAAGGTGGC
CGACTATCCGTTCACGACGCTCCATCCGAACCTCGGCGTGGTCCGTGTGGACCATGAGCAGTCGTTCGTCGTGGCGGACA
TTCCGGGCCTGATCGAAGGCGCCGCCGAAGGCGCCGGTCTCGGACATCAGTTCCTGCGCCACCTGCAACGTACCGGGCTG
CTGCTGCATATCGTCGACATCGCACCGTTCGACGAGAATGTCGATCCCGTTGCCGAGGCCAAGGCCATCGTCAACGAACT
GAAGAAATACGACGAGACGCTGTACGACAAGCCGCGCTGGCTGGTGCTGAACAAGCTCGACGTGGTTCCGGAAGAGGAAC
GTGCCGCGCGCGTGAAGGATTTCGTCAAGCGCTACAAGTGGAAGGGGCCGGTGTTCCATATCTCGGCCCTGACCGGCGAG
GGCTGCCGCGAGCTGGTCTACGCGATCAAGGACCATCTCGCCGCGCTCAAGGCAGAGGAAGCTGCCGCGCTGGCCGAGCC
CGATATCCGCCTCGACGACCGCCTGCATAACGTCGATCGAGACGACAGCAAAGCGTAA

Upstream 100 bases:

>100_bases
CGCAGTGACTGCGGGGCTTTTTTGTTTTCTGCCAAGATAAAATGGCGCTGACCCGTCGAGGGCCGGCGGCGACAAGCCCG
AACCACCACGGAAAACCAAC

Downstream 100 bases:

>100_bases
CGCACTACAACAAGGCACCACGGAGACAGGACCCGCCATGCAATCGGTCATCGCCCAGGCAAAACGCATTGTCGTCAAAG
TAGGTTCGAGTCTGGTTACC

Product: GTPase CgtA

Products: NA

Alternate protein names: GTP-binding protein obg [H]

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MKFIDEARIEAIAGNGGNGSASFRREKFVPFGGPDGGDGGRGGSVFAQADRNINTLIDFRYAKKHVARNGENGRGSDCYG
AAGEDVTLRMPVGTLISDMDTGEVIADLTEHGQLVCLAEGGMGGWGNLHFKSSTNRAPRQQVDGKPGERRMLKLELKVLA
DVGLLGMPNAGKSTFISHVSNARPKVADYPFTTLHPNLGVVRVDHEQSFVVADIPGLIEGAAEGAGLGHQFLRHLQRTGL
LLHIVDIAPFDENVDPVAEAKAIVNELKKYDETLYDKPRWLVLNKLDVVPEEERAARVKDFVKRYKWKGPVFHISALTGE
GCRELVYAIKDHLAALKAEEAAALAEPDIRLDDRLHNVDRDDSKA

Sequences:

>Translated_365_residues
MKFIDEARIEAIAGNGGNGSASFRREKFVPFGGPDGGDGGRGGSVFAQADRNINTLIDFRYAKKHVARNGENGRGSDCYG
AAGEDVTLRMPVGTLISDMDTGEVIADLTEHGQLVCLAEGGMGGWGNLHFKSSTNRAPRQQVDGKPGERRMLKLELKVLA
DVGLLGMPNAGKSTFISHVSNARPKVADYPFTTLHPNLGVVRVDHEQSFVVADIPGLIEGAAEGAGLGHQFLRHLQRTGL
LLHIVDIAPFDENVDPVAEAKAIVNELKKYDETLYDKPRWLVLNKLDVVPEEERAARVKDFVKRYKWKGPVFHISALTGE
GCRELVYAIKDHLAALKAEEAAALAEPDIRLDDRLHNVDRDDSKA
>Mature_365_residues
MKFIDEARIEAIAGNGGNGSASFRREKFVPFGGPDGGDGGRGGSVFAQADRNINTLIDFRYAKKHVARNGENGRGSDCYG
AAGEDVTLRMPVGTLISDMDTGEVIADLTEHGQLVCLAEGGMGGWGNLHFKSSTNRAPRQQVDGKPGERRMLKLELKVLA
DVGLLGMPNAGKSTFISHVSNARPKVADYPFTTLHPNLGVVRVDHEQSFVVADIPGLIEGAAEGAGLGHQFLRHLQRTGL
LLHIVDIAPFDENVDPVAEAKAIVNELKKYDETLYDKPRWLVLNKLDVVPEEERAARVKDFVKRYKWKGPVFHISALTGE
GCRELVYAIKDHLAALKAEEAAALAEPDIRLDDRLHNVDRDDSKA

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI24308117, Length=328, Percent_Identity=39.6341463414634, Blast_Score=196, Evalue=3e-50,
Organism=Homo sapiens, GI111955139, Length=363, Percent_Identity=34.9862258953168, Blast_Score=175, Evalue=6e-44,
Organism=Homo sapiens, GI111955063, Length=199, Percent_Identity=36.6834170854271, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI58761500, Length=173, Percent_Identity=30.0578034682081, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI4758796, Length=156, Percent_Identity=32.6923076923077, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1789574, Length=356, Percent_Identity=54.7752808988764, Blast_Score=357, Evalue=1e-100,
Organism=Escherichia coli, GI1787454, Length=132, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1790615, Length=240, Percent_Identity=28.3333333333333, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17508313, Length=333, Percent_Identity=38.1381381381381, Blast_Score=162, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI17552324, Length=324, Percent_Identity=28.3950617283951, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17509631, Length=139, Percent_Identity=34.5323741007194, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6321962, Length=198, Percent_Identity=38.3838383838384, Blast_Score=126, Evalue=5e-30,
Organism=Drosophila melanogaster, GI24585318, Length=305, Percent_Identity=37.0491803278689, Blast_Score=173, Evalue=1e-43,
Organism=Drosophila melanogaster, GI20129375, Length=329, Percent_Identity=37.9939209726444, Blast_Score=166, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24640873, Length=133, Percent_Identity=34.5864661654135, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24640877, Length=133, Percent_Identity=34.5864661654135, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24640875, Length=133, Percent_Identity=34.5864661654135, Blast_Score=75, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 39764; Mature: 39764

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFIDEARIEAIAGNGGNGSASFRREKFVPFGGPDGGDGGRGGSVFAQADRNINTLIDFR
CCCCCCCCEEEEECCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHH
YAKKHVARNGENGRGSDCYGAAGEDVTLRMPVGTLISDMDTGEVIADLTEHGQLVCLAEG
HHHHHHHCCCCCCCCCCCCCCCCCCEEEEECHHHHHHCCCCHHHHHHHHHCCCEEEEECC
GMGGWGNLHFKSSTNRAPRQQVDGKPGERRMLKLELKVLADVGLLGMPNAGKSTFISHVS
CCCCCCCEEECCCCCCCCHHHCCCCCCCCCEEEHHHHHHHCCCCCCCCCCCHHHHHHHHH
NARPKVADYPFTTLHPNLGVVRVDHEQSFVVADIPGLIEGAAEGAGLGHQFLRHLQRTGL
CCCCCCCCCCCEEECCCCCEEEECCCCCEEEECCCHHHHHCCCCCCHHHHHHHHHHHCCE
LLHIVDIAPFDENVDPVAEAKAIVNELKKYDETLYDKPRWLVLNKLDVVPEEERAARVKD
EEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHH
FVKRYKWKGPVFHISALTGEGCRELVYAIKDHLAALKAEEAAALAEPDIRLDDRLHNVDR
HHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCC
DDSKA
CCCCC
>Mature Secondary Structure
MKFIDEARIEAIAGNGGNGSASFRREKFVPFGGPDGGDGGRGGSVFAQADRNINTLIDFR
CCCCCCCCEEEEECCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHH
YAKKHVARNGENGRGSDCYGAAGEDVTLRMPVGTLISDMDTGEVIADLTEHGQLVCLAEG
HHHHHHHCCCCCCCCCCCCCCCCCCEEEEECHHHHHHCCCCHHHHHHHHHCCCEEEEECC
GMGGWGNLHFKSSTNRAPRQQVDGKPGERRMLKLELKVLADVGLLGMPNAGKSTFISHVS
CCCCCCCEEECCCCCCCCHHHCCCCCCCCCEEEHHHHHHHCCCCCCCCCCCHHHHHHHHH
NARPKVADYPFTTLHPNLGVVRVDHEQSFVVADIPGLIEGAAEGAGLGHQFLRHLQRTGL
CCCCCCCCCCCEEECCCCCEEEECCCCCEEEECCCHHHHHCCCCCCHHHHHHHHHHHCCE
LLHIVDIAPFDENVDPVAEAKAIVNELKKYDETLYDKPRWLVLNKLDVVPEEERAARVKD
EEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHH
FVKRYKWKGPVFHISALTGEGCRELVYAIKDHLAALKAEEAAALAEPDIRLDDRLHNVDR
HHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCC
DDSKA
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA