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The map label for this gene is pehR [H]

Identifier: 94312021

GI number: 94312021

Start: 3347564

End: 3349246

Strand: Reverse

Name: pehR [H]

Synonym: Rmet_3090

Alternate gene names: 94312021

Gene position: 3349246-3347564 (Counterclockwise)

Preceding gene: 94312022

Following gene: 94312020

Centisome position: 85.26

GC content: 68.87

Gene sequence:

>1683_bases
ATGCCTCCCAGATTGTCCGCACCCGATCCGATTCTCGTCATCGACGACGAGGCCGACCTGCGCGAGCTGCTGGATATCTC
GCTGCGACGCATGGGGCATGACGTGGTGATGGCCGGTTCGCTGGCCGAGGCCCGCCTGCGTCTGGCCGAGCGGCGCTACA
GCCTGGTGCTGACCGACATGCGGCTCGGCGATGGCCTCGGCATCGAGATCGTGCGCCAGTTGTCGGCGTCGCCCGAGCGC
ACCCCGGTGGCCGTGATCACGGCGTATGGCAGCGCGGACAACGCGGTGGATGCGCTCAAGGCCGGCGCGTTCGACTACAT
CGCCAAGCCGGTATCTCTCGAGCAACTCCGCACGCTGATTCTCAACGCACTGGGCCGTCACCAGCGCGGTGCGAACGGTA
ACGACACATCCGATCAGGCCGATGCGGGGGACGCGTCCGACGCGACCGATGGGGCCAGTCTGGGCGATCGCGCGGCCGGG
CTGCTACCGGGGGTCTCGCCGGCAATTCACGAGGTACGGCGCTCGCTGCCGCGCCTGGCGCGCAGCATGGCACCGGTGGT
GATCAGCGGCGAATCCGGCAGCGGCAAGGAACGGGCGGCGCGAGCGATTCACGCGATCAGCGCGCGCTCGGCGCATCCAT
TTGTGGCCGTGAACTGCGGCGCGATCCCTGAGACGCTGATGGAGGCCGAGTTCTTCGGTCACGTCAAAGGCGCCTTTACT
GGGGCCGACGCCGAGCGCGGCGGGTTCTTCCAGGCCGCCAATGGCGGCACGCTGCTGCTCGATGAGGTCGCGGACTTGCC
GCTGGCGATGCAGGTGAAGCTGCTGCGCGCGTTGCAGGAACGCCGCGTGCGCAAGATCGGCGCTAGCAAGGAAGACAGCG
TGGATGTGCGCGTCATGTGCGCCAGCCACAAGGATCTGGCGGCGATGGTCGCCGCCGGAGCATTCCGGCAGGACTTGTAC
TACCGCCTCAACGTGCTTGAACTCCGGATGCCCACGATGCGCGAGCGCGCCGAGGACATCCCGGTGCTTGCCCGCGCGAT
TCTCGAGCATCTGGCCGTGCGCTACGGCGATGCGCATCCCAAGCGGCTGTCGCGCGCGGCGCTGGAATGGCTCTGCGCGT
ACGAATTTCCGGGGAACGTGCGCGAGCTCGAGAACCTGCTCGAGCGTGCCTACGCGTTCGCTGAGAGCGAGGAGATCGAG
GTGGCCGACCTGGGGCCGCTCGACACCGGCATCGAGCGTGCCGCGCTGATGCAGACGGCCATGGCGGCGCCGCCGTTGAC
TGCCGTGCCGCCGGCAGCCATGTATCACCGGTGGGGTAACGCCGGAGCCTGGGGCGTGCCCGCTCCGGCGACACCCGTGG
CGGTGATGCCAGAACCGGCGCCCGTGCCGGCCCCGATTCCCGTGGCAGGGCCGGTCGCCGTGCCTGCCCCCGATGCTGGC
GCGCCGGCTGCCACCACGTTCCCAATTAATCTTCCCGCGCACCTGGAGGCGATGGAGCGCGAGCTGATCCTGCGCGCCTT
GCGGCAGACCGGCTTCAACCGGACCGCCGCGGCGCCGCTGCTGGGTTTGAACTTCCGCCAGTTGCGGTATCGGATCGAAC
AGCTCGGTATCTGCGAGGAGGATGGGCGCAGCGGCCGGGACGATAGCGAATCGCTGGCCGAAGGGGAGGGGCGCGATGTC
TGA

Upstream 100 bases:

>100_bases
ATACACTTCCCGGCAAGGCATTCGTGTTGACGCTGCGCAACGAAGTGCCCGACGTCGCGAATGCCCAGCCATTTCAACCA
TCGGCCAAGCTCTGATATCC

Downstream 100 bases:

>100_bases
CGCCGCAGGCCGGGTCCGCGACTGGCGGCCCAACGCCGACGGCTGGGTCCCCGCAGCCCGCCACGTGCCGTCCCCGAACT
TCGACGCCCGCCCCGAAGGC

Product: Polygalacturonase histidine response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 560; Mature: 559

Protein sequence:

>560_residues
MPPRLSAPDPILVIDDEADLRELLDISLRRMGHDVVMAGSLAEARLRLAERRYSLVLTDMRLGDGLGIEIVRQLSASPER
TPVAVITAYGSADNAVDALKAGAFDYIAKPVSLEQLRTLILNALGRHQRGANGNDTSDQADAGDASDATDGASLGDRAAG
LLPGVSPAIHEVRRSLPRLARSMAPVVISGESGSGKERAARAIHAISARSAHPFVAVNCGAIPETLMEAEFFGHVKGAFT
GADAERGGFFQAANGGTLLLDEVADLPLAMQVKLLRALQERRVRKIGASKEDSVDVRVMCASHKDLAAMVAAGAFRQDLY
YRLNVLELRMPTMRERAEDIPVLARAILEHLAVRYGDAHPKRLSRAALEWLCAYEFPGNVRELENLLERAYAFAESEEIE
VADLGPLDTGIERAALMQTAMAAPPLTAVPPAAMYHRWGNAGAWGVPAPATPVAVMPEPAPVPAPIPVAGPVAVPAPDAG
APAATTFPINLPAHLEAMERELILRALRQTGFNRTAAAPLLGLNFRQLRYRIEQLGICEEDGRSGRDDSESLAEGEGRDV

Sequences:

>Translated_560_residues
MPPRLSAPDPILVIDDEADLRELLDISLRRMGHDVVMAGSLAEARLRLAERRYSLVLTDMRLGDGLGIEIVRQLSASPER
TPVAVITAYGSADNAVDALKAGAFDYIAKPVSLEQLRTLILNALGRHQRGANGNDTSDQADAGDASDATDGASLGDRAAG
LLPGVSPAIHEVRRSLPRLARSMAPVVISGESGSGKERAARAIHAISARSAHPFVAVNCGAIPETLMEAEFFGHVKGAFT
GADAERGGFFQAANGGTLLLDEVADLPLAMQVKLLRALQERRVRKIGASKEDSVDVRVMCASHKDLAAMVAAGAFRQDLY
YRLNVLELRMPTMRERAEDIPVLARAILEHLAVRYGDAHPKRLSRAALEWLCAYEFPGNVRELENLLERAYAFAESEEIE
VADLGPLDTGIERAALMQTAMAAPPLTAVPPAAMYHRWGNAGAWGVPAPATPVAVMPEPAPVPAPIPVAGPVAVPAPDAG
APAATTFPINLPAHLEAMERELILRALRQTGFNRTAAAPLLGLNFRQLRYRIEQLGICEEDGRSGRDDSESLAEGEGRDV
>Mature_559_residues
PPRLSAPDPILVIDDEADLRELLDISLRRMGHDVVMAGSLAEARLRLAERRYSLVLTDMRLGDGLGIEIVRQLSASPERT
PVAVITAYGSADNAVDALKAGAFDYIAKPVSLEQLRTLILNALGRHQRGANGNDTSDQADAGDASDATDGASLGDRAAGL
LPGVSPAIHEVRRSLPRLARSMAPVVISGESGSGKERAARAIHAISARSAHPFVAVNCGAIPETLMEAEFFGHVKGAFTG
ADAERGGFFQAANGGTLLLDEVADLPLAMQVKLLRALQERRVRKIGASKEDSVDVRVMCASHKDLAAMVAAGAFRQDLYY
RLNVLELRMPTMRERAEDIPVLARAILEHLAVRYGDAHPKRLSRAALEWLCAYEFPGNVRELENLLERAYAFAESEEIEV
ADLGPLDTGIERAALMQTAMAAPPLTAVPPAAMYHRWGNAGAWGVPAPATPVAVMPEPAPVPAPIPVAGPVAVPAPDAGA
PAATTFPINLPAHLEAMERELILRALRQTGFNRTAAAPLLGLNFRQLRYRIEQLGICEEDGRSGRDDSESLAEGEGRDV

Specific function: Member of the two-component regulatory system pilS/pilR that regulates the expression of type 4 fimbriae. When activated by pilS it acts in conjunction with sigma-54 as a transcriptional activator [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=389, Percent_Identity=43.4447300771208, Blast_Score=301, Evalue=1e-82,
Organism=Escherichia coli, GI1788550, Length=406, Percent_Identity=39.4088669950739, Blast_Score=288, Evalue=7e-79,
Organism=Escherichia coli, GI1788905, Length=389, Percent_Identity=39.5886889460154, Blast_Score=265, Evalue=8e-72,
Organism=Escherichia coli, GI1790299, Length=398, Percent_Identity=36.9346733668342, Blast_Score=251, Evalue=1e-67,
Organism=Escherichia coli, GI1789233, Length=246, Percent_Identity=45.9349593495935, Blast_Score=220, Evalue=2e-58,
Organism=Escherichia coli, GI87082117, Length=236, Percent_Identity=46.1864406779661, Blast_Score=216, Evalue=3e-57,
Organism=Escherichia coli, GI1789087, Length=238, Percent_Identity=47.0588235294118, Blast_Score=212, Evalue=6e-56,
Organism=Escherichia coli, GI1786524, Length=292, Percent_Identity=41.0958904109589, Blast_Score=206, Evalue=3e-54,
Organism=Escherichia coli, GI87082152, Length=231, Percent_Identity=46.3203463203463, Blast_Score=204, Evalue=2e-53,
Organism=Escherichia coli, GI1787583, Length=240, Percent_Identity=40.8333333333333, Blast_Score=179, Evalue=4e-46,
Organism=Escherichia coli, GI87081872, Length=374, Percent_Identity=33.4224598930481, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI1789828, Length=244, Percent_Identity=34.4262295081967, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI87081858, Length=225, Percent_Identity=32.4444444444444, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1786838, Length=173, Percent_Identity=26.0115606936416, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1786911, Length=117, Percent_Identity=35.042735042735, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 59897; Mature: 59766

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPRLSAPDPILVIDDEADLRELLDISLRRMGHDVVMAGSLAEARLRLAERRYSLVLTDM
CCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHEEEEEE
RLGDGLGIEIVRQLSASPERTPVAVITAYGSADNAVDALKAGAFDYIAKPVSLEQLRTLI
ECCCCCHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHCCHHHHCCCCCHHHHHHHH
LNALGRHQRGANGNDTSDQADAGDASDATDGASLGDRAAGLLPGVSPAIHEVRRSLPRLA
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHH
RSMAPVVISGESGSGKERAARAIHAISARSAHPFVAVNCGAIPETLMEAEFFGHVKGAFT
HHCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCC
GADAERGGFFQAANGGTLLLDEVADLPLAMQVKLLRALQERRVRKIGASKEDSVDVRVMC
CCCCCCCCEEEECCCCEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEE
ASHKDLAAMVAAGAFRQDLYYRLNVLELRMPTMRERAEDIPVLARAILEHLAVRYGDAHP
CCCHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCH
KRLSRAALEWLCAYEFPGNVRELENLLERAYAFAESEEIEVADLGPLDTGIERAALMQTA
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHH
MAAPPLTAVPPAAMYHRWGNAGAWGVPAPATPVAVMPEPAPVPAPIPVAGPVAVPAPDAG
HCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCC
APAATTFPINLPAHLEAMERELILRALRQTGFNRTAAAPLLGLNFRQLRYRIEQLGICEE
CCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCHHCCHHHCCCHHHHHHHHHHCCCCCC
DGRSGRDDSESLAEGEGRDV
CCCCCCCCHHHHHCCCCCCC
>Mature Secondary Structure 
PPRLSAPDPILVIDDEADLRELLDISLRRMGHDVVMAGSLAEARLRLAERRYSLVLTDM
CCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHEEEEEE
RLGDGLGIEIVRQLSASPERTPVAVITAYGSADNAVDALKAGAFDYIAKPVSLEQLRTLI
ECCCCCHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHCCHHHHCCCCCHHHHHHHH
LNALGRHQRGANGNDTSDQADAGDASDATDGASLGDRAAGLLPGVSPAIHEVRRSLPRLA
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHH
RSMAPVVISGESGSGKERAARAIHAISARSAHPFVAVNCGAIPETLMEAEFFGHVKGAFT
HHCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCC
GADAERGGFFQAANGGTLLLDEVADLPLAMQVKLLRALQERRVRKIGASKEDSVDVRVMC
CCCCCCCCEEEECCCCEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEE
ASHKDLAAMVAAGAFRQDLYYRLNVLELRMPTMRERAEDIPVLARAILEHLAVRYGDAHP
CCCHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCH
KRLSRAALEWLCAYEFPGNVRELENLLERAYAFAESEEIEVADLGPLDTGIERAALMQTA
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHH
MAAPPLTAVPPAAMYHRWGNAGAWGVPAPATPVAVMPEPAPVPAPIPVAGPVAVPAPDAG
HCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCC
APAATTFPINLPAHLEAMERELILRALRQTGFNRTAAAPLLGLNFRQLRYRIEQLGICEE
CCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCHHCCHHHCCCHHHHHHHHHHCCCCCC
DGRSGRDDSESLAEGEGRDV
CCCCCCCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1317379; 8097014; 7911557; 10984043 [H]