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The map label for this gene is pehS [H]

Identifier: 94312022

GI number: 94312022

Start: 3349252

End: 3351288

Strand: Reverse

Name: pehS [H]

Synonym: Rmet_3091

Alternate gene names: 94312022

Gene position: 3351288-3349252 (Counterclockwise)

Preceding gene: 94312023

Following gene: 94312021

Centisome position: 85.32

GC content: 65.73

Gene sequence:

>2037_bases
ATGACGGCGCCGGCGTCGGCCTGGTCCCATCTGAACGGCTGGCGCGTGCTGGTCAAGCTCTGGCGTCAGTCGGAGCCACC
TGAATTCCACTGGCGGCTGCAGCGGTACTTCTGCTGGACGCGGCTTGCCGTCGCTGTGTTGCTGGTCGGCTATGCCTGGC
TGCCGCTCGAACGCGCCGCCGCCGGCGCCGACGTCTTCAACGTGGCGACGAACGCGCGCTTGGCCTCGGCCATGCCGGTC
GTGCTGCCTTATCTGGCCATCGCCCTCGTCACGCTGTTCGGTACGTTGTGGCGCAACCACTTTCACGTGCGCGTGCGCGT
GCAGGTGCTGGTCGATCTGGTCTTGCTGGCCTCCATCTACGCGGCGCTCGGTCACTTCGGCAGCCAGGGCGAAGGGCTGG
CGATGATTTTCCTGCTGCCCGTGATCGAGGCGGGCGCGCTGACCAGCCTGACGTTTGCGCTGTTTGCCGCTTCGGTGTCG
GCGCTGCTCGTGATGGGCCCGCCGCTCCTGCAAACATTGATCACGCGCCAGGTCGATGTGAACCTGCTCGGTTCCGGCCT
GTTCGGGCTTGTGTTCATGATCGCGGCGCTCGTGATGTACATGCTTGCCAATCGCCAGATCGCCCAGGAGCAACTGGCGC
TGGCGCGCGAACAGGAACTGCGCCTGCAGCAACTCGTGAACCGGCTGATGGTCAATGACATGCAGGACGGCGTGATGCTG
GTCCGTGCCAATGGCGTCGTTGTGGCGGCAAATCCCGCCGCGCTCGTGCTGCTTGGCGTGCAGCAAAACGAGCGGATTCG
CGAAGGGCAGGTTCGTGTTGGCGAGCGCGAGAACGTGTTGTTCGACCTGCGTCGAATGCCGCGTCTGCAACCGCTGCTGG
AGATGCTGCGCGACTGGATCCGCATGAAGGACGACGTCCCGCGCATCTTGCAATTGCTGCCGCTGCCATCGCGCCCGTCC
TCCTCGGCGCGCAACTCGATGCACACACGGCTGCGCCTTCGCTTCGTGCTGCCCGGCCTGGCGGGGCTGCGTTCGACGCT
GGCGGGTGCACTGACCTCGCCATCGGGCCTCGACACAACCAGCTGGAACGATATGTCGCCCGAGGGCGCCGCGCGCCTGC
GGCTGGCCATCGCCCAGAACGAGGCCATGGCCTGGAGCCCGGCGGACGAGGCGCTGCTGCGTAGCGAGATGCGTGACACG
GTGCTGGTGCACATCGAAAGCTGGGAGCGTATTGCCGAGCAGGTCCAGCAGGAAAAACTTGCCGCGATGGGTCGACTGGT
CGCCAGCGTCGCGCACCAGATCCGCAATCCGCTCGCGGCGATCAGCCAGGCCAACGAACTGCTGGCCGACTCAGGCGGTG
GCGAGGGCAACATCGATGCCCGCCTGCTGCGCATCATCAGCGATAACGTGCGACGGCTCGATCAGGTGATTTCCGATGTG
CTGCAACTGTCGCGCCGCCCGCGCACCGGGCATAGCGCTGTCGATTTGGCCAAGGCGCTGCCCGAAGTCGTGGACCGGTG
GCGGCTGGAAATGCGTTCGCGAGCCGGCGCCCGCGCCGAGGTGAACGCCAATGCGATCCGCATCACCGTCGATCTGAAGG
GGCCGGTGATCTTCGACATGTCGCAATTGCAGCAGGTGCTCGGCAACCTGCTCGACAACGCATGGCGCTATTGCAGCCGG
CTGCCGGGCGCGATCCGCCTGCTGGCGCATACGCTCGACCAGCACCATGCCGAACTGATTGTCTGGAACGATGGCGCGGA
AGTCACGCGCGAGCAGCAGCGCAGCCTGTTCGAGCCGTTCTTCACCAGTAATCCGCAAGGTACCGGGCTGGGGCTGTTCA
TGGCGCGCGAGCTGTGCGGCGCGAACGACGCCCAGGTGCGCTACGGCGCGATCGTGCTAGAGGATCTGCTCGACCGCACC
GGCATGCTCGTCGGGGCTCGCGATACACTTCCCGGCAAGGCATTCGTGTTGACGCTGCGCAACGAAGTGCCCGACGTCGC
GAATGCCCAGCCATTTCAACCATCGGCCAAGCTCTGA

Upstream 100 bases:

>100_bases
ATCTGCCGCGCGGCGATGCCATCGCATGGCACGGCCTGCATTACTGCCGCCGTAGCCATTTGCCAGACATGCCCGGCGAG
GGCGATCACGGCACGCGTTC

Downstream 100 bases:

>100_bases
TATCCATGCCTCCCAGATTGTCCGCACCCGATCCGATTCTCGTCATCGACGACGAGGCCGACCTGCGCGAGCTGCTGGAT
ATCTCGCTGCGACGCATGGG

Product: Polygalacturonase histidine kinase regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 678; Mature: 677

Protein sequence:

>678_residues
MTAPASAWSHLNGWRVLVKLWRQSEPPEFHWRLQRYFCWTRLAVAVLLVGYAWLPLERAAAGADVFNVATNARLASAMPV
VLPYLAIALVTLFGTLWRNHFHVRVRVQVLVDLVLLASIYAALGHFGSQGEGLAMIFLLPVIEAGALTSLTFALFAASVS
ALLVMGPPLLQTLITRQVDVNLLGSGLFGLVFMIAALVMYMLANRQIAQEQLALAREQELRLQQLVNRLMVNDMQDGVML
VRANGVVVAANPAALVLLGVQQNERIREGQVRVGERENVLFDLRRMPRLQPLLEMLRDWIRMKDDVPRILQLLPLPSRPS
SSARNSMHTRLRLRFVLPGLAGLRSTLAGALTSPSGLDTTSWNDMSPEGAARLRLAIAQNEAMAWSPADEALLRSEMRDT
VLVHIESWERIAEQVQQEKLAAMGRLVASVAHQIRNPLAAISQANELLADSGGGEGNIDARLLRIISDNVRRLDQVISDV
LQLSRRPRTGHSAVDLAKALPEVVDRWRLEMRSRAGARAEVNANAIRITVDLKGPVIFDMSQLQQVLGNLLDNAWRYCSR
LPGAIRLLAHTLDQHHAELIVWNDGAEVTREQQRSLFEPFFTSNPQGTGLGLFMARELCGANDAQVRYGAIVLEDLLDRT
GMLVGARDTLPGKAFVLTLRNEVPDVANAQPFQPSAKL

Sequences:

>Translated_678_residues
MTAPASAWSHLNGWRVLVKLWRQSEPPEFHWRLQRYFCWTRLAVAVLLVGYAWLPLERAAAGADVFNVATNARLASAMPV
VLPYLAIALVTLFGTLWRNHFHVRVRVQVLVDLVLLASIYAALGHFGSQGEGLAMIFLLPVIEAGALTSLTFALFAASVS
ALLVMGPPLLQTLITRQVDVNLLGSGLFGLVFMIAALVMYMLANRQIAQEQLALAREQELRLQQLVNRLMVNDMQDGVML
VRANGVVVAANPAALVLLGVQQNERIREGQVRVGERENVLFDLRRMPRLQPLLEMLRDWIRMKDDVPRILQLLPLPSRPS
SSARNSMHTRLRLRFVLPGLAGLRSTLAGALTSPSGLDTTSWNDMSPEGAARLRLAIAQNEAMAWSPADEALLRSEMRDT
VLVHIESWERIAEQVQQEKLAAMGRLVASVAHQIRNPLAAISQANELLADSGGGEGNIDARLLRIISDNVRRLDQVISDV
LQLSRRPRTGHSAVDLAKALPEVVDRWRLEMRSRAGARAEVNANAIRITVDLKGPVIFDMSQLQQVLGNLLDNAWRYCSR
LPGAIRLLAHTLDQHHAELIVWNDGAEVTREQQRSLFEPFFTSNPQGTGLGLFMARELCGANDAQVRYGAIVLEDLLDRT
GMLVGARDTLPGKAFVLTLRNEVPDVANAQPFQPSAKL
>Mature_677_residues
TAPASAWSHLNGWRVLVKLWRQSEPPEFHWRLQRYFCWTRLAVAVLLVGYAWLPLERAAAGADVFNVATNARLASAMPVV
LPYLAIALVTLFGTLWRNHFHVRVRVQVLVDLVLLASIYAALGHFGSQGEGLAMIFLLPVIEAGALTSLTFALFAASVSA
LLVMGPPLLQTLITRQVDVNLLGSGLFGLVFMIAALVMYMLANRQIAQEQLALAREQELRLQQLVNRLMVNDMQDGVMLV
RANGVVVAANPAALVLLGVQQNERIREGQVRVGERENVLFDLRRMPRLQPLLEMLRDWIRMKDDVPRILQLLPLPSRPSS
SARNSMHTRLRLRFVLPGLAGLRSTLAGALTSPSGLDTTSWNDMSPEGAARLRLAIAQNEAMAWSPADEALLRSEMRDTV
LVHIESWERIAEQVQQEKLAAMGRLVASVAHQIRNPLAAISQANELLADSGGGEGNIDARLLRIISDNVRRLDQVISDVL
QLSRRPRTGHSAVDLAKALPEVVDRWRLEMRSRAGARAEVNANAIRITVDLKGPVIFDMSQLQQVLGNLLDNAWRYCSRL
PGAIRLLAHTLDQHHAELIVWNDGAEVTREQQRSLFEPFFTSNPQGTGLGLFMARELCGANDAQVRYGAIVLEDLLDRTG
MLVGARDTLPGKAFVLTLRNEVPDVANAQPFQPSAKL

Specific function: Member of the two-component regulatory system pilS/pilR involved in the regulation of the expression of type 4 fimbriae. PilS may function as a membrane-associated protein kinase that phosphorylates pilR in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=231, Percent_Identity=29.4372294372294, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1790436, Length=210, Percent_Identity=30.4761904761905, Blast_Score=78, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 75039; Mature: 74908

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPASAWSHLNGWRVLVKLWRQSEPPEFHWRLQRYFCWTRLAVAVLLVGYAWLPLERAA
CCCCCHHHHHCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGADVFNVATNARLASAMPVVLPYLAIALVTLFGTLWRNHFHVRVRVQVLVDLVLLASIY
CCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHH
AALGHFGSQGEGLAMIFLLPVIEAGALTSLTFALFAASVSALLVMGPPLLQTLITRQVDV
HHHHCCCCCCCCEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
NLLGSGLFGLVFMIAALVMYMLANRQIAQEQLALAREQELRLQQLVNRLMVNDMQDGVML
HHHCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
VRANGVVVAANPAALVLLGVQQNERIREGQVRVGERENVLFDLRRMPRLQPLLEMLRDWI
EEECCEEEEECCCEEEEEECCCCCCHHCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHH
RMKDDVPRILQLLPLPSRPSSSARNSMHTRLRLRFVLPGLAGLRSTLAGALTSPSGLDTT
HCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCC
SWNDMSPEGAARLRLAIAQNEAMAWSPADEALLRSEMRDTVLVHIESWERIAEQVQQEKL
CCCCCCCCCHHHEEEEEECCCCCCCCCHHHHHHHHHCCHHEEEEEHHHHHHHHHHHHHHH
AAMGRLVASVAHQIRNPLAAISQANELLADSGGGEGNIDARLLRIISDNVRRLDQVISDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LQLSRRPRTGHSAVDLAKALPEVVDRWRLEMRSRAGARAEVNANAIRITVDLKGPVIFDM
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEEEEEEECCCEEECH
SQLQQVLGNLLDNAWRYCSRLPGAIRLLAHTLDQHHAELIVWNDGAEVTREQQRSLFEPF
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHH
FTSNPQGTGLGLFMARELCGANDAQVRYGAIVLEDLLDRTGMLVGARDTLPGKAFVLTLR
HCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEECCCCCCCCEEEEEEC
NEVPDVANAQPFQPSAKL
CCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TAPASAWSHLNGWRVLVKLWRQSEPPEFHWRLQRYFCWTRLAVAVLLVGYAWLPLERAA
CCCCHHHHHCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGADVFNVATNARLASAMPVVLPYLAIALVTLFGTLWRNHFHVRVRVQVLVDLVLLASIY
CCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHH
AALGHFGSQGEGLAMIFLLPVIEAGALTSLTFALFAASVSALLVMGPPLLQTLITRQVDV
HHHHCCCCCCCCEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
NLLGSGLFGLVFMIAALVMYMLANRQIAQEQLALAREQELRLQQLVNRLMVNDMQDGVML
HHHCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
VRANGVVVAANPAALVLLGVQQNERIREGQVRVGERENVLFDLRRMPRLQPLLEMLRDWI
EEECCEEEEECCCEEEEEECCCCCCHHCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHH
RMKDDVPRILQLLPLPSRPSSSARNSMHTRLRLRFVLPGLAGLRSTLAGALTSPSGLDTT
HCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCC
SWNDMSPEGAARLRLAIAQNEAMAWSPADEALLRSEMRDTVLVHIESWERIAEQVQQEKL
CCCCCCCCCHHHEEEEEECCCCCCCCCHHHHHHHHHCCHHEEEEEHHHHHHHHHHHHHHH
AAMGRLVASVAHQIRNPLAAISQANELLADSGGGEGNIDARLLRIISDNVRRLDQVISDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LQLSRRPRTGHSAVDLAKALPEVVDRWRLEMRSRAGARAEVNANAIRITVDLKGPVIFDM
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEEEEEEECCCEEECH
SQLQQVLGNLLDNAWRYCSRLPGAIRLLAHTLDQHHAELIVWNDGAEVTREQQRSLFEPF
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHH
FTSNPQGTGLGLFMARELCGANDAQVRYGAIVLEDLLDRTGMLVGARDTLPGKAFVLTLR
HCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEECCCCCCCCEEEEEEC
NEVPDVANAQPFQPSAKL
CCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8097014; 10984043 [H]