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The map label for this gene is cobO

Identifier: 94311855

GI number: 94311855

Start: 3178690

End: 3179244

Strand: Reverse

Name: cobO

Synonym: Rmet_2923

Alternate gene names: NA

Gene position: 3179244-3178690 (Counterclockwise)

Preceding gene: 94311866

Following gene: 94311854

Centisome position: 80.94

GC content: 67.21

Gene sequence:

>555_bases
ATGGGTAATCGCCTGTCCAAAATTGCCACGCGCACCGGCGATGCCGGCACCACGGGCCTCGGCGATGGCAGCCGGGTCGG
CAAGAACAGCCTGCGCATCGTCGCGATCGGCGACGTGGATGAGCTGAATTCCCATATCGGCCTGCTGCTGACCGAACCGG
ATCTGCCCGAGGACGTCCGCGCCGCGCTGCTCCATATCCAGCACGACCTGTTTGACCTGGGTGGTGAACTCTCCATCCCG
GGCTATACCTTGCTCAAGGCACCCCAGGTGGCCCAGCTCGACGACTGGCTGGCCCATTACAATGCCGCCCTGCCACGGTT
GGCCGAATTCATCCTGCCGGGCGGAAGCCGGCCCGCCGCGCAGGCCCACATCTGCCGTACGGTCTGCCGCCGGGCGGAAC
GTGCGCTTGTGGAGTTGGGCGCCGCCGAAGCGCTCAACGAGGCGCCGCGCCAGTACCTGAACAGGCTGTCAGACCTGCTG
TTCGTGCTGGCCCGTGTGCTGAACCGCGCGGGTGGCGGGAGCGACGTGCTCTGGCAGCGTGAGCGGGAGTCCTGA

Upstream 100 bases:

>100_bases
TCGCCTTCCACGTCTCCCATACGTCCCCGGTACGCGCCGCCCGGCCCCGGAGGGTCCATAATTGCGCCACTTCTAAAACA
CTGACCACAAGGAGACCGGC

Downstream 100 bases:

>100_bases
ATAGTTACGTATGAGCCACTTATTAGCCTGACTCGTTTTTCCGAGAAATTTACTCGGATTTGCGAATTTCGCCCTTGAAA
TGGCCCGCGATGGCCACATT

Product: cobalamin adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase [H]

Number of amino acids: Translated: 184; Mature: 183

Protein sequence:

>184_residues
MGNRLSKIATRTGDAGTTGLGDGSRVGKNSLRIVAIGDVDELNSHIGLLLTEPDLPEDVRAALLHIQHDLFDLGGELSIP
GYTLLKAPQVAQLDDWLAHYNAALPRLAEFILPGGSRPAAQAHICRTVCRRAERALVELGAAEALNEAPRQYLNRLSDLL
FVLARVLNRAGGGSDVLWQRERES

Sequences:

>Translated_184_residues
MGNRLSKIATRTGDAGTTGLGDGSRVGKNSLRIVAIGDVDELNSHIGLLLTEPDLPEDVRAALLHIQHDLFDLGGELSIP
GYTLLKAPQVAQLDDWLAHYNAALPRLAEFILPGGSRPAAQAHICRTVCRRAERALVELGAAEALNEAPRQYLNRLSDLL
FVLARVLNRAGGGSDVLWQRERES
>Mature_183_residues
GNRLSKIATRTGDAGTTGLGDGSRVGKNSLRIVAIGDVDELNSHIGLLLTEPDLPEDVRAALLHIQHDLFDLGGELSIPG
YTLLKAPQVAQLDDWLAHYNAALPRLAEFILPGGSRPAAQAHICRTVCRRAERALVELGAAEALNEAPRQYLNRLSDLLF
VLARVLNRAGGGSDVLWQRERES

Specific function: Unknown

COG id: COG2096

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI16418349, Length=192, Percent_Identity=38.0208333333333, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI115534154, Length=167, Percent_Identity=34.1317365269461, Blast_Score=86, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017858
- InterPro:   IPR002779
- InterPro:   IPR016030
- ProDom:   PD007457 [H]

Pfam domain/function: PF01923 Cob_adeno_trans [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 19904; Mature: 19773

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNRLSKIATRTGDAGTTGLGDGSRVGKNSLRIVAIGDVDELNSHIGLLLTEPDLPEDVR
CCCHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHCCCCEEEECCCCCHHHH
AALLHIQHDLFDLGGELSIPGYTLLKAPQVAQLDDWLAHYNAALPRLAEFILPGGSRPAA
HHHHHHHHHHHHCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
QAHICRTVCRRAERALVELGAAEALNEAPRQYLNRLSDLLFVLARVLNRAGGGSDVLWQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
ERES
CCCC
>Mature Secondary Structure 
GNRLSKIATRTGDAGTTGLGDGSRVGKNSLRIVAIGDVDELNSHIGLLLTEPDLPEDVR
CCHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHCCCCEEEECCCCCHHHH
AALLHIQHDLFDLGGELSIPGYTLLKAPQVAQLDDWLAHYNAALPRLAEFILPGGSRPAA
HHHHHHHHHHHHCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
QAHICRTVCRRAERALVELGAAEALNEAPRQYLNRLSDLLFVLARVLNRAGGGSDVLWQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
ERES
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]