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The map label for this gene is gpo [C]

Identifier: 94311866

GI number: 94311866

Start: 3189323

End: 3189817

Strand: Reverse

Name: gpo [C]

Synonym: Rmet_2934

Alternate gene names: 94311866

Gene position: 3189817-3189323 (Counterclockwise)

Preceding gene: 94311867

Following gene: 94311855

Centisome position: 81.21

GC content: 60.61

Gene sequence:

>495_bases
ATGAGCAATGTGTACCAGTTCGAAGCCAATTCGCTGTCCGGCCAGCCTCAGCCGCTGGCCGACTACCGCGGCAAGGTGCT
GCTGATCGTCAACACCGCGAGCGAATGTGGCTTCACGCCGCAATACGCGGGCCTGCAGACGCTGCAGGCGTCCTATCAGG
CGCGCGGCTTCGACGTGCTTGGCTTTCCCTGCAACCAGTTTGGCAAGCAGGAGCCTGGTGACGCCGAACAAATTGGCGCG
TTTTGCGAATCCCGATTTCACGTCACGTTCCCGATGTTCGAGAAAATCGACGTGAACGGCGCGGACGCGCATCCGCTCTA
CAAGTGGCTGACGTCGGAGAAGCGGGGGTTCCTCGGTACCCAGGCGATCAAGTGGAATTTCACCAAGTTCCTGCTGCGCC
GCGACGGTACCGTCTTCAAGCGTTATGCGTCCACAACCAAGCCCGAGGAAATCCGCGCAGACATCGAGTCGCTGCTCGCC
GAACAACCGGCGTGA

Upstream 100 bases:

>100_bases
GACAACGATCTCGGCGCCGGCACCGAACACCTGAACGTGATCTGAGCGGACGCGGTATTCTCACGGCCTGTACTGCCCCC
ATACACCGCAGGAGACCACG

Downstream 100 bases:

>100_bases
GATAAGCCGGCGGGCTCCGTGCCCGACTATCCCTGCGTGTCGGAATGGATGGTGCGGAGGAATCCGTTGAGCGAACGCTC
TGACGTCTCGAGGAAATGCT

Product: glutathione peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 164; Mature: 163

Protein sequence:

>164_residues
MSNVYQFEANSLSGQPQPLADYRGKVLLIVNTASECGFTPQYAGLQTLQASYQARGFDVLGFPCNQFGKQEPGDAEQIGA
FCESRFHVTFPMFEKIDVNGADAHPLYKWLTSEKRGFLGTQAIKWNFTKFLLRRDGTVFKRYASTTKPEEIRADIESLLA
EQPA

Sequences:

>Translated_164_residues
MSNVYQFEANSLSGQPQPLADYRGKVLLIVNTASECGFTPQYAGLQTLQASYQARGFDVLGFPCNQFGKQEPGDAEQIGA
FCESRFHVTFPMFEKIDVNGADAHPLYKWLTSEKRGFLGTQAIKWNFTKFLLRRDGTVFKRYASTTKPEEIRADIESLLA
EQPA
>Mature_163_residues
SNVYQFEANSLSGQPQPLADYRGKVLLIVNTASECGFTPQYAGLQTLQASYQARGFDVLGFPCNQFGKQEPGDAEQIGAF
CESRFHVTFPMFEKIDVNGADAHPLYKWLTSEKRGFLGTQAIKWNFTKFLLRRDGTVFKRYASTTKPEEIRADIESLLAE
QPA

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI75709200, Length=156, Percent_Identity=46.1538461538462, Blast_Score=135, Evalue=2e-32,
Organism=Homo sapiens, GI90903240, Length=156, Percent_Identity=46.1538461538462, Blast_Score=134, Evalue=3e-32,
Organism=Homo sapiens, GI15618997, Length=160, Percent_Identity=44.375, Blast_Score=129, Evalue=1e-30,
Organism=Homo sapiens, GI90903238, Length=131, Percent_Identity=48.0916030534351, Blast_Score=115, Evalue=2e-26,
Organism=Homo sapiens, GI192455698, Length=160, Percent_Identity=35.625, Blast_Score=114, Evalue=5e-26,
Organism=Homo sapiens, GI41406084, Length=187, Percent_Identity=39.0374331550802, Blast_Score=107, Evalue=6e-24,
Organism=Homo sapiens, GI6006001, Length=181, Percent_Identity=36.4640883977901, Blast_Score=100, Evalue=5e-22,
Organism=Homo sapiens, GI4557629, Length=184, Percent_Identity=35.3260869565217, Blast_Score=100, Evalue=9e-22,
Organism=Homo sapiens, GI33186887, Length=178, Percent_Identity=33.1460674157303, Blast_Score=84, Evalue=8e-17,
Organism=Homo sapiens, GI32967607, Length=179, Percent_Identity=32.4022346368715, Blast_Score=81, Evalue=4e-16,
Organism=Escherichia coli, GI1788003, Length=161, Percent_Identity=44.7204968944099, Blast_Score=140, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI17535473, Length=160, Percent_Identity=48.75, Blast_Score=157, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17506887, Length=163, Percent_Identity=47.8527607361963, Blast_Score=156, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI71993584, Length=157, Percent_Identity=40.7643312101911, Blast_Score=128, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI193210707, Length=164, Percent_Identity=40.2439024390244, Blast_Score=116, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI193209493, Length=182, Percent_Identity=34.0659340659341, Blast_Score=100, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17550320, Length=182, Percent_Identity=34.6153846153846, Blast_Score=100, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI71993573, Length=94, Percent_Identity=39.3617021276596, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI71999642, Length=76, Percent_Identity=39.4736842105263, Blast_Score=68, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17507603, Length=102, Percent_Identity=37.2549019607843, Blast_Score=64, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322228, Length=161, Percent_Identity=52.1739130434783, Blast_Score=184, Evalue=5e-48,
Organism=Saccharomyces cerevisiae, GI6319721, Length=160, Percent_Identity=50.625, Blast_Score=178, Evalue=4e-46,
Organism=Saccharomyces cerevisiae, GI6322826, Length=163, Percent_Identity=42.9447852760736, Blast_Score=148, Evalue=4e-37,
Organism=Drosophila melanogaster, GI24656772, Length=160, Percent_Identity=44.375, Blast_Score=138, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24656777, Length=160, Percent_Identity=44.375, Blast_Score=137, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24656767, Length=160, Percent_Identity=44.375, Blast_Score=137, Evalue=2e-33,
Organism=Drosophila melanogaster, GI85726443, Length=159, Percent_Identity=40.8805031446541, Blast_Score=116, Evalue=6e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 18414; Mature: 18283

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1 ; PS00763 GLUTATHIONE_PEROXID_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNVYQFEANSLSGQPQPLADYRGKVLLIVNTASECGFTPQYAGLQTLQASYQARGFDVL
CCCEEEEECCCCCCCCCCHHHCCCCEEEEEECCHHCCCCCCHHHHHHHHHHHHHCCCEEE
GFPCNQFGKQEPGDAEQIGAFCESRFHVTFPMFEKIDVNGADAHPLYKWLTSEKRGFLGT
CCCHHHHCCCCCCCHHHHHHHHHCCEEEECCCCEEECCCCCCCHHHHHHHHHCCCCCCCC
QAIKWNFTKFLLRRDGTVFKRYASTTKPEEIRADIESLLAEQPA
CEEHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SNVYQFEANSLSGQPQPLADYRGKVLLIVNTASECGFTPQYAGLQTLQASYQARGFDVL
CCEEEEECCCCCCCCCCHHHCCCCEEEEEECCHHCCCCCCHHHHHHHHHHHHHCCCEEE
GFPCNQFGKQEPGDAEQIGAFCESRFHVTFPMFEKIDVNGADAHPLYKWLTSEKRGFLGT
CCCHHHHCCCCCCCHHHHHHHHHCCEEEECCCCEEECCCCCCCHHHHHHHHHCCCCCCCC
QAIKWNFTKFLLRRDGTVFKRYASTTKPEEIRADIESLLAEQPA
CEEHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]