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The map label for this gene is hutU1 [H]

Identifier: 94311786

GI number: 94311786

Start: 3102291

End: 3103997

Strand: Reverse

Name: hutU1 [H]

Synonym: Rmet_2854

Alternate gene names: 94311786

Gene position: 3103997-3102291 (Counterclockwise)

Preceding gene: 94311787

Following gene: 94311785

Centisome position: 79.02

GC content: 64.56

Gene sequence:

>1707_bases
ATGAACGCCAACGAACACCAATTCACCCAGACGCTGCGTGGCCCGCGGGAGATCCGCGCGCCGCATGGCAGCCAGCTTCA
CTGCAAGAACTGGCTGATCGAAGCCGCCTATCGCATGATCCAGAACAACCTCGACCCCGACGTGGCGGAGCGCCCGCAGG
ATCTGGTGGTCTATGGCGGCATTGGCAAGGCCGCGCGCAACTGGGAGTGCTTCGACGCGATTCTCGACTGCCTGCGCCGC
CTGGGCGAAGACGAGTCGCTGCTCGTGCAGTCGGGCAAGCCCGTCGGGGTATTCCGCACCCATGCCGATGCGCCGCGTGT
GCTGATCGCCAACTCGAACCTGGTGCCGCACTGGGCAAACTGGGACAAGTTCAACGAACTCGATCGCGCCGGGCTGATGA
TGTACGGTCAGATGACTGCTGGCTCGTGGATCTACATCGGCACGCAGGGCATCGTGCAGGGCACGTTCGAGACCTTTGCC
GAAGCAGGCAACCAGCACTACAACGGCGACCTGACCGGCAAGTGGATCCTGACCGCTGGCCTGGGCGGGATGGGTGGCGC
GCAGCCGCTGGCCGGCGTGCTGGCCGGTGCTTGTGTGCTGGCGATCGAATGCCAGGAATCGCGCATCGATTTCCGCATCC
GCACGCGCTATCTCGACAAGAAGGCCACCACGCTCGATGAAGCGCTGGCGATGATTGCCGAGGCCACGAAAAATGGCCAG
GCGATCTCGGTGGGGCTGCTCGGCAATGCCGCAGAGATCGTGCCGGAACTGGTGCGTCGCGCGCAGGCCGGCGGTATGCG
GCCGGACATCGTCACCGACCAGACTTCCGCCCATGATCTCGTCAATGGCTACCTGCCAGAGGGCTGGACCGTGGCGCAAT
GGGAGGACCTGCGCCAGCGCGATCCAAAGGCCGTGGAAGCGGCCGCGCGTACGTCGATCGTCAAGCATGTGGAGGCGATG
CTCGCGTTCCAGCAGATGGGCGTGCCCACGCTCGACTACGGCAACAACATCCGTCAGGTGGCGTTCGACGAAGGCGTGAA
GAACGCCTTCGATTTCCCCGGCTTCGTGCCGGCGTATATCCGTCCGCTGTTTTGCCGCGGCAAGGGGCCGTTCCGCTGGG
TGGCGCTCTCCGGCGACCCCGAGGATATCTACAAGACCGACGCCAAGATGAAGGAACTGTTCCCGGAGGACAAGCACCTG
CACCGCTGGCTCGACATGGCGCGCGACCGCATCGCGTTCCAGGGCTTGCCCGCGCGCATCTGCTGGGTTGGTCTCGACGA
GCGCCATCGCGCGGGCCTGGCCTTCAATGAAATGGTGAAGTCTGGCGAACTGAAGGCGCCCGTCGTGATCGGCCGCGATC
ACCTCGACTGCGGCTCGGTGGCATCACCGAACCGCGAGACGGAGGCGATGCGTGACGGCTCCGACGCCGTGTCTGATTGG
CCACTGCTCAACGCGCTGCTGAACACGGCTGGCGGCGCCACGTGGGTCAGCCTGCATCACGGCGGCGGTGTTGGCATGGG
CTTCTCGCAACATGCTGGCGTGGTGATCGTTTGCGATGGTACGGACGCCGCGGCCAAGCGCATCGAACGCGTGCTGTGGA
ACGATCCTGCCACCGGTGTGATGCGTCATGCCGATGCCGGCTACGAATCCGCCATCGAATGCGCGAAGGAAAAGGGACTG
AATCTGCCGATGGTGAACCGTACATGA

Upstream 100 bases:

>100_bases
GGGAGATCTTGCCGACGAACGTCGGCGCATGAGCTTCGTGAACCGCTAGTCCATTCTCCATTCTCCATTCGAGCAGCCTT
CATCCATCCCGGGACCGACC

Downstream 100 bases:

>100_bases
AGTTTGGACTCGACAGGATCGTGCCGACGCCGTGGAAGAACGGTGGCGGCACCACGCGCGAAATCGCCGTATGGCCGCCG
GGCGCGGGCATGGATACGTT

Product: urocanate hydratase

Products: NA

Alternate protein names: Urocanase; Imidazolonepropionate hydrolase [H]

Number of amino acids: Translated: 568; Mature: 568

Protein sequence:

>568_residues
MNANEHQFTQTLRGPREIRAPHGSQLHCKNWLIEAAYRMIQNNLDPDVAERPQDLVVYGGIGKAARNWECFDAILDCLRR
LGEDESLLVQSGKPVGVFRTHADAPRVLIANSNLVPHWANWDKFNELDRAGLMMYGQMTAGSWIYIGTQGIVQGTFETFA
EAGNQHYNGDLTGKWILTAGLGGMGGAQPLAGVLAGACVLAIECQESRIDFRIRTRYLDKKATTLDEALAMIAEATKNGQ
AISVGLLGNAAEIVPELVRRAQAGGMRPDIVTDQTSAHDLVNGYLPEGWTVAQWEDLRQRDPKAVEAAARTSIVKHVEAM
LAFQQMGVPTLDYGNNIRQVAFDEGVKNAFDFPGFVPAYIRPLFCRGKGPFRWVALSGDPEDIYKTDAKMKELFPEDKHL
HRWLDMARDRIAFQGLPARICWVGLDERHRAGLAFNEMVKSGELKAPVVIGRDHLDCGSVASPNRETEAMRDGSDAVSDW
PLLNALLNTAGGATWVSLHHGGGVGMGFSQHAGVVIVCDGTDAAAKRIERVLWNDPATGVMRHADAGYESAIECAKEKGL
NLPMVNRT

Sequences:

>Translated_568_residues
MNANEHQFTQTLRGPREIRAPHGSQLHCKNWLIEAAYRMIQNNLDPDVAERPQDLVVYGGIGKAARNWECFDAILDCLRR
LGEDESLLVQSGKPVGVFRTHADAPRVLIANSNLVPHWANWDKFNELDRAGLMMYGQMTAGSWIYIGTQGIVQGTFETFA
EAGNQHYNGDLTGKWILTAGLGGMGGAQPLAGVLAGACVLAIECQESRIDFRIRTRYLDKKATTLDEALAMIAEATKNGQ
AISVGLLGNAAEIVPELVRRAQAGGMRPDIVTDQTSAHDLVNGYLPEGWTVAQWEDLRQRDPKAVEAAARTSIVKHVEAM
LAFQQMGVPTLDYGNNIRQVAFDEGVKNAFDFPGFVPAYIRPLFCRGKGPFRWVALSGDPEDIYKTDAKMKELFPEDKHL
HRWLDMARDRIAFQGLPARICWVGLDERHRAGLAFNEMVKSGELKAPVVIGRDHLDCGSVASPNRETEAMRDGSDAVSDW
PLLNALLNTAGGATWVSLHHGGGVGMGFSQHAGVVIVCDGTDAAAKRIERVLWNDPATGVMRHADAGYESAIECAKEKGL
NLPMVNRT
>Mature_568_residues
MNANEHQFTQTLRGPREIRAPHGSQLHCKNWLIEAAYRMIQNNLDPDVAERPQDLVVYGGIGKAARNWECFDAILDCLRR
LGEDESLLVQSGKPVGVFRTHADAPRVLIANSNLVPHWANWDKFNELDRAGLMMYGQMTAGSWIYIGTQGIVQGTFETFA
EAGNQHYNGDLTGKWILTAGLGGMGGAQPLAGVLAGACVLAIECQESRIDFRIRTRYLDKKATTLDEALAMIAEATKNGQ
AISVGLLGNAAEIVPELVRRAQAGGMRPDIVTDQTSAHDLVNGYLPEGWTVAQWEDLRQRDPKAVEAAARTSIVKHVEAM
LAFQQMGVPTLDYGNNIRQVAFDEGVKNAFDFPGFVPAYIRPLFCRGKGPFRWVALSGDPEDIYKTDAKMKELFPEDKHL
HRWLDMARDRIAFQGLPARICWVGLDERHRAGLAFNEMVKSGELKAPVVIGRDHLDCGSVASPNRETEAMRDGSDAVSDW
PLLNALLNTAGGATWVSLHHGGGVGMGFSQHAGVVIVCDGTDAAAKRIERVLWNDPATGVMRHADAGYESAIECAKEKGL
NLPMVNRT

Specific function: Unknown

COG id: COG2987

COG function: function code E; Urocanate hydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the urocanase family [H]

Homologues:

Organism=Homo sapiens, GI21389467, Length=562, Percent_Identity=34.3416370106762, Blast_Score=299, Evalue=4e-81,
Organism=Homo sapiens, GI260306182, Length=214, Percent_Identity=39.2523364485981, Blast_Score=156, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI71997891, Length=584, Percent_Identity=33.7328767123288, Blast_Score=304, Evalue=7e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000193 [H]

Pfam domain/function: PF01175 Urocanase [H]

EC number: =4.2.1.49 [H]

Molecular weight: Translated: 62275; Mature: 62275

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: PS01233 UROCANASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNANEHQFTQTLRGPREIRAPHGSQLHCKNWLIEAAYRMIQNNLDPDVAERPQDLVVYGG
CCCCHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHCCCCCEEEECC
IGKAARNWECFDAILDCLRRLGEDESLLVQSGKPVGVFRTHADAPRVLIANSNLVPHWAN
CCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCCCCEEEEECCCCCCCCCC
WDKFNELDRAGLMMYGQMTAGSWIYIGTQGIVQGTFETFAEAGNQHYNGDLTGKWILTAG
CHHHHHHHHCCEEEEEEECCCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEC
LGGMGGAQPLAGVLAGACVLAIECQESRIDFRIRTRYLDKKATTLDEALAMIAEATKNGQ
CCCCCCCHHHHHHHHHHHEEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCC
AISVGLLGNAAEIVPELVRRAQAGGMRPDIVTDQTSAHDLVNGYLPEGWTVAQWEDLRQR
EEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCCEEHHHHHHHHC
DPKAVEAAARTSIVKHVEAMLAFQQMGVPTLDYGNNIRQVAFDEGVKNAFDFPGFVPAYI
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHCCCCCCCHHHH
RPLFCRGKGPFRWVALSGDPEDIYKTDAKMKELFPEDKHLHRWLDMARDRIAFQGLPARI
CHHEECCCCCEEEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEE
CWVGLDERHRAGLAFNEMVKSGELKAPVVIGRDHLDCGSVASPNRETEAMRDGSDAVSDW
EEECCCCHHCCCCHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHCCCCHHHHH
PLLNALLNTAGGATWVSLHHGGGVGMGFSQHAGVVIVCDGTDAAAKRIERVLWNDPATGV
HHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCHHH
MRHADAGYESAIECAKEKGLNLPMVNRT
HHHCCCCHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MNANEHQFTQTLRGPREIRAPHGSQLHCKNWLIEAAYRMIQNNLDPDVAERPQDLVVYGG
CCCCHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHCCCCCEEEECC
IGKAARNWECFDAILDCLRRLGEDESLLVQSGKPVGVFRTHADAPRVLIANSNLVPHWAN
CCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCCCCEEEEECCCCCCCCCC
WDKFNELDRAGLMMYGQMTAGSWIYIGTQGIVQGTFETFAEAGNQHYNGDLTGKWILTAG
CHHHHHHHHCCEEEEEEECCCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEC
LGGMGGAQPLAGVLAGACVLAIECQESRIDFRIRTRYLDKKATTLDEALAMIAEATKNGQ
CCCCCCCHHHHHHHHHHHEEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCC
AISVGLLGNAAEIVPELVRRAQAGGMRPDIVTDQTSAHDLVNGYLPEGWTVAQWEDLRQR
EEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCCEEHHHHHHHHC
DPKAVEAAARTSIVKHVEAMLAFQQMGVPTLDYGNNIRQVAFDEGVKNAFDFPGFVPAYI
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHCCCCCCCHHHH
RPLFCRGKGPFRWVALSGDPEDIYKTDAKMKELFPEDKHLHRWLDMARDRIAFQGLPARI
CHHEECCCCCEEEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEE
CWVGLDERHRAGLAFNEMVKSGELKAPVVIGRDHLDCGSVASPNRETEAMRDGSDAVSDW
EEECCCCHHCCCCHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHCCCCHHHHH
PLLNALLNTAGGATWVSLHHGGGVGMGFSQHAGVVIVCDGTDAAAKRIERVLWNDPATGV
HHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCHHH
MRHADAGYESAIECAKEKGLNLPMVNRT
HHHCCCCHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]