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The map label for this gene is btuC [C]

Identifier: 94311720

GI number: 94311720

Start: 3034192

End: 3035199

Strand: Reverse

Name: btuC [C]

Synonym: Rmet_2788

Alternate gene names: 94311720

Gene position: 3035199-3034192 (Counterclockwise)

Preceding gene: 94311721

Following gene: 94311719

Centisome position: 77.27

GC content: 69.35

Gene sequence:

>1008_bases
ATGGCTGAGCTGCGGCGCGCGCTGATCGTCTGGGGTGTCCTCGCGCTGGCAGGGCTGGCCGTCTTCGGCCTGTCGCTGGC
GATCGGCAGCGTGTCGCTCGATGCCGGGCAACTCTGGCAGGCGCTGAGCGGCGCGGACGATGGCACCGCAGGCGCCATCG
TCCGCGAACTACGGCTGCCACGTGCCGCCGCCGCGTTTGCCTGTGGCGGGCTGCTGGCGCTTTCCGGCGCATTGATGCAG
GTGTTGTTGCGCAATCCGCTGGCCGAACCCTACGTGCTCGGCGTCTCCGGCGGGGCGTCCACGGGTGCGCTGCTGTCGAT
GCTGCTGATGCTTCCGCAATGGATCGTGCACACCAGCGCGGCGGGTGGCGCGCTGGTGTCCATGCTGCTCGTCGCCACGC
TTGCCCGCCGTGACCTGCTCAACCCAAAAGTGCAGGGCGGACACCAGGAGGCCGGCGCGCGGTTGCTGCTGACCGGTGTC
ATCCTGGCCGCGGGGTGGGGCGCGCTGATCACGCTGATCCTCGCCATCGCGCCGGAATCGCGCCTGCGCGGCATGTTGTT
CTGGCTGACCGGTGACCTCGGTGGCACGGCCGCCTATGGCGCGGCGTTGGCCACCTTGATCGCCGCACTGCTGCTGGCCA
TGCCGATGGCGCGGGCGCTCAACGTGATGCTGCTGGGTGAGACCGTGGCGCAATCGCTGGGTGTTCGCGTTGGCCGCGTG
CGCCTGGCTACCTTCCTGATTTCCTCCATTTCGATTGCCGCCGCCATCACGACGGCCGGGTCGATTGGCTTCGTCGGCCT
GGTGGTGCCACACATGGTGCGCCTGGCCTGGGGGAACGACCAGCGCCTGCTGCTGCCGGCATCAGTGCTGCTGGGCGGCA
CCTTGCTGATGGCTGCCGACCTGATCGCGCGTACCGTGGTTGCCCCCACGCAACTGCCGGTGGGCGTCATCACGGCGCTG
CTGGGCGTGCCGACCTTCCTCTACCTGCTGCTGCGGAGACCGCGATGA

Upstream 100 bases:

>100_bases
CGACAAGAACTACCAGCTGGCCTACCCCTACAACACGCAGGGCAGGGCCGGCTTCATCACGCTGGGATGGCGTCAGAAGT
GATGCCGCGCGCGGGGAGCC

Downstream 100 bases:

>100_bases
GCCATTGGTCCGAGCCGCTCACAGACTGTCCGCAGTTGACCCTGCGGCAACTCGGCCTGCACGCCGGGAGCCGCGTGCTG
CTCGATGGCCTCTCGATGTC

Product: vitamin B12 ABC transporter membrane protein BtuC

Products: ADP; phosphate; cob(I)alamin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MAELRRALIVWGVLALAGLAVFGLSLAIGSVSLDAGQLWQALSGADDGTAGAIVRELRLPRAAAAFACGGLLALSGALMQ
VLLRNPLAEPYVLGVSGGASTGALLSMLLMLPQWIVHTSAAGGALVSMLLVATLARRDLLNPKVQGGHQEAGARLLLTGV
ILAAGWGALITLILAIAPESRLRGMLFWLTGDLGGTAAYGAALATLIAALLLAMPMARALNVMLLGETVAQSLGVRVGRV
RLATFLISSISIAAAITTAGSIGFVGLVVPHMVRLAWGNDQRLLLPASVLLGGTLLMAADLIARTVVAPTQLPVGVITAL
LGVPTFLYLLLRRPR

Sequences:

>Translated_335_residues
MAELRRALIVWGVLALAGLAVFGLSLAIGSVSLDAGQLWQALSGADDGTAGAIVRELRLPRAAAAFACGGLLALSGALMQ
VLLRNPLAEPYVLGVSGGASTGALLSMLLMLPQWIVHTSAAGGALVSMLLVATLARRDLLNPKVQGGHQEAGARLLLTGV
ILAAGWGALITLILAIAPESRLRGMLFWLTGDLGGTAAYGAALATLIAALLLAMPMARALNVMLLGETVAQSLGVRVGRV
RLATFLISSISIAAAITTAGSIGFVGLVVPHMVRLAWGNDQRLLLPASVLLGGTLLMAADLIARTVVAPTQLPVGVITAL
LGVPTFLYLLLRRPR
>Mature_334_residues
AELRRALIVWGVLALAGLAVFGLSLAIGSVSLDAGQLWQALSGADDGTAGAIVRELRLPRAAAAFACGGLLALSGALMQV
LLRNPLAEPYVLGVSGGASTGALLSMLLMLPQWIVHTSAAGGALVSMLLVATLARRDLLNPKVQGGHQEAGARLLLTGVI
LAAGWGALITLILAIAPESRLRGMLFWLTGDLGGTAAYGAALATLIAALLLAMPMARALNVMLLGETVAQSLGVRVGRVR
LATFLISSISIAAAITTAGSIGFVGLVVPHMVRLAWGNDQRLLLPASVLLGGTLLMAADLIARTVVAPTQLPVGVITALL
GVPTFLYLLLRRPR

Specific function: Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788004, Length=305, Percent_Identity=37.3770491803279, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1790740, Length=337, Percent_Identity=36.4985163204748, Blast_Score=147, Evalue=9e-37,
Organism=Escherichia coli, GI1790741, Length=349, Percent_Identity=35.243553008596, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1786805, Length=317, Percent_Identity=37.8548895899054, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1786347, Length=295, Percent_Identity=31.5254237288136, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI1786804, Length=340, Percent_Identity=35.2941176470588, Blast_Score=96, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 34340; Mature: 34209

Theoretical pI: Translated: 11.75; Mature: 11.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAELRRALIVWGVLALAGLAVFGLSLAIGSVSLDAGQLWQALSGADDGTAGAIVRELRLP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHCC
RAAAAFACGGLLALSGALMQVLLRNPLAEPYVLGVSGGASTGALLSMLLMLPQWIVHTSA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCC
AGGALVSMLLVATLARRDLLNPKVQGGHQEAGARLLLTGVILAAGWGALITLILAIAPES
CHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
RLRGMLFWLTGDLGGTAAYGAALATLIAALLLAMPMARALNVMLLGETVAQSLGVRVGRV
HHCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
RLATFLISSISIAAAITTAGSIGFVGLVVPHMVRLAWGNDQRLLLPASVLLGGTLLMAAD
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHH
LIARTVVAPTQLPVGVITALLGVPTFLYLLLRRPR
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AELRRALIVWGVLALAGLAVFGLSLAIGSVSLDAGQLWQALSGADDGTAGAIVRELRLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHCC
RAAAAFACGGLLALSGALMQVLLRNPLAEPYVLGVSGGASTGALLSMLLMLPQWIVHTSA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCC
AGGALVSMLLVATLARRDLLNPKVQGGHQEAGARLLLTGVILAAGWGALITLILAIAPES
CHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
RLRGMLFWLTGDLGGTAAYGAALATLIAALLLAMPMARALNVMLLGETVAQSLGVRVGRV
HHCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
RLATFLISSISIAAAITTAGSIGFVGLVVPHMVRLAWGNDQRLLLPASVLLGGTLLMAAD
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHH
LIARTVVAPTQLPVGVITALLGVPTFLYLLLRRPR
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; cob(I)alamin [Periplasm]; H2O [C]

Specific reaction: ATP + cob(I)alamin [Periplasm] + H2O = ADP + phosphate + cob(I)alamin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]