BacMap

Definition	Cupriavidus metallidurans CH34 chromosome, complete genome.
Accession	NC_007973
Length	3,928,089

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The map label for this gene is btuD [H]

Identifier: 94311719

GI number: 94311719

Start: 3033386

End: 3034195

Strand: Reverse

Name: btuD [H]

Synonym: Rmet_2787

Alternate gene names: 94311719

Gene position: 3034195-3033386 (Counterclockwise)

Preceding gene: 94311720

Following gene: 94311718

Centisome position: 77.24

GC content: 68.15

Gene sequence:

>810_bases
ATGAGCCATTGGTCCGAGCCGCTCACAGACTGTCCGCAGTTGACCCTGCGGCAACTCGGCCTGCACGCCGGGAGCCGCGT
GCTGCTCGATGGCCTCTCGATGTCGATCGGCGCGGGGCAGCTCTGGTGCATCGTCGGCCCGAACGGGGTCGGCAAGTCCA
CGCTGATGGGCGTGCTGGCCGGTCTGCGCGCGCCCGACAGCGGCGCGGCCGAGGTCGACGAAATTGCGGTCACGCAGATC
GCCCCTGCCACGCTGGCGCGGCAGCGGGCCTATTTGCCCCAGGCTGTGCACGATACGTTCTCGATGCTGGTCGAGGATGC
CGTGCGCATCGGTCGGCATCCGCATCTGAGCGGCTGGGGCTGGGGCCAGCGTGACGATGACCGGATCGTGGATGATGTCA
TCGACGCGCTCGATCTCGAGCCACTGCGTGGCCGCGACGTGCTGACACTGTCCGGTGGCGAACGCCAGCGCGTGTCGCTG
GCTGCCGCGCTGGCGCAGCAGGCGCCGCTGCTGCTCCTGGACGAACCCGTGGCGCACCTGGACCTGCGGCACCAGATCAT
GGTGCTCGACCTGCTGCAGCGCCTGACCCGATCGGGCCGCCACGCAGTTGTCGTGATCGTGCATGACCTGACCCTCGCGC
ATCGCTATGCCACCCACGCGCTGCTGATGGCCGAGGATGGTCACGCGCTGCACGGCCCGGCGCACGAGGTCCTGACTCCC
GCGCAGTGCTCCCATGCGCTGCGTACCCCGATTATCAGCATCAGCGACGGCACCCATACCGCGCTGATCCCAGATGGAAA
TCAGACATGA

Upstream 100 bases:

>100_bases
TCGCGCGTACCGTGGTTGCCCCCACGCAACTGCCGGTGGGCGTCATCACGGCGCTGCTGGGCGTGCCGACCTTCCTCTAC
CTGCTGCTGCGGAGACCGCG

Downstream 100 bases:

>100_bases
GCGATACCCCGAATACCAACGATGACGCCGGCCGCGATGCCCGTCACAAGGCACGCATGGTCCGCAAGAAGGAGGTGGTC
GATTCCAAGATCGCCGCGGC

Product: ABC-type cobalamin transporter ATPase BtuD

Products: NA

Alternate protein names: Ferric hydroxamate uptake protein C; Ferrichrome transport ATP-binding protein FhuC; Iron(III)-hydroxamate import ATP-binding protein FhuC [H]

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MSHWSEPLTDCPQLTLRQLGLHAGSRVLLDGLSMSIGAGQLWCIVGPNGVGKSTLMGVLAGLRAPDSGAAEVDEIAVTQI
APATLARQRAYLPQAVHDTFSMLVEDAVRIGRHPHLSGWGWGQRDDDRIVDDVIDALDLEPLRGRDVLTLSGGERQRVSL
AAALAQQAPLLLLDEPVAHLDLRHQIMVLDLLQRLTRSGRHAVVVIVHDLTLAHRYATHALLMAEDGHALHGPAHEVLTP
AQCSHALRTPIISISDGTHTALIPDGNQT

Sequences:

>Translated_269_residues
MSHWSEPLTDCPQLTLRQLGLHAGSRVLLDGLSMSIGAGQLWCIVGPNGVGKSTLMGVLAGLRAPDSGAAEVDEIAVTQI
APATLARQRAYLPQAVHDTFSMLVEDAVRIGRHPHLSGWGWGQRDDDRIVDDVIDALDLEPLRGRDVLTLSGGERQRVSL
AAALAQQAPLLLLDEPVAHLDLRHQIMVLDLLQRLTRSGRHAVVVIVHDLTLAHRYATHALLMAEDGHALHGPAHEVLTP
AQCSHALRTPIISISDGTHTALIPDGNQT
>Mature_268_residues
SHWSEPLTDCPQLTLRQLGLHAGSRVLLDGLSMSIGAGQLWCIVGPNGVGKSTLMGVLAGLRAPDSGAAEVDEIAVTQIA
PATLARQRAYLPQAVHDTFSMLVEDAVRIGRHPHLSGWGWGQRDDDRIVDDVIDALDLEPLRGRDVLTLSGGERQRVSLA
AALAQQAPLLLLDEPVAHLDLRHQIMVLDLLQRLTRSGRHAVVVIVHDLTLAHRYATHALLMAEDGHALHGPAHEVLTPA
QCSHALRTPIISISDGTHTALIPDGNQT

Specific function: Part of the ABC transporter complex FhuBGCD involved in iron(3+)-hydroxamate import. Responsible for energy coupling to the transport system [H]

COG id: COG1120

COG function: function code PH; ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI108773784, Length=211, Percent_Identity=27.9620853080569, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI108773782, Length=211, Percent_Identity=27.9620853080569, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI46592898, Length=188, Percent_Identity=29.2553191489362, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI46592956, Length=188, Percent_Identity=29.2553191489362, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI46592964, Length=188, Percent_Identity=29.2553191489362, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI46592978, Length=188, Percent_Identity=29.2553191489362, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI46592971, Length=188, Percent_Identity=29.2553191489362, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI46592915, Length=188, Percent_Identity=29.2553191489362, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI215820660, Length=183, Percent_Identity=28.9617486338798, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI20143975, Length=183, Percent_Identity=28.9617486338798, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI153792144, Length=164, Percent_Identity=29.2682926829268, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI9665248, Length=239, Percent_Identity=29.2887029288703, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI62526033, Length=205, Percent_Identity=29.7560975609756, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI73747915, Length=213, Percent_Identity=27.6995305164319, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI27262624, Length=166, Percent_Identity=31.9277108433735, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI27262626, Length=166, Percent_Identity=31.9277108433735, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI27477115, Length=166, Percent_Identity=28.3132530120482, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI171184400, Length=192, Percent_Identity=29.6875, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1790739, Length=231, Percent_Identity=35.9307359307359, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1786803, Length=222, Percent_Identity=34.6846846846847, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1786345, Length=206, Percent_Identity=36.8932038834951, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI1788002, Length=222, Percent_Identity=34.2342342342342, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1786698, Length=202, Percent_Identity=30.6930693069307, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI87081791, Length=220, Percent_Identity=31.3636363636364, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI87081834, Length=192, Percent_Identity=33.8541666666667, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1786253, Length=217, Percent_Identity=29.9539170506912, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI87082267, Length=220, Percent_Identity=27.2727272727273, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787029, Length=234, Percent_Identity=27.3504273504274, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1789891, Length=199, Percent_Identity=30.6532663316583, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1788165, Length=203, Percent_Identity=30.5418719211823, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787712, Length=238, Percent_Identity=26.0504201680672, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1790544, Length=233, Percent_Identity=28.3261802575107, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1786563, Length=209, Percent_Identity=31.1004784688995, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789873, Length=218, Percent_Identity=29.8165137614679, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788450, Length=203, Percent_Identity=31.5270935960591, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787370, Length=212, Percent_Identity=30.6603773584906, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1786398, Length=197, Percent_Identity=27.4111675126904, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787164, Length=213, Percent_Identity=32.3943661971831, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1790467, Length=196, Percent_Identity=28.5714285714286, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1787112, Length=238, Percent_Identity=28.1512605042017, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1789032, Length=212, Percent_Identity=30.6603773584906, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1788210, Length=199, Percent_Identity=30.1507537688442, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789593, Length=235, Percent_Identity=27.2340425531915, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787105, Length=212, Percent_Identity=30.188679245283, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787143, Length=217, Percent_Identity=28.110599078341, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1789751, Length=220, Percent_Identity=31.3636363636364, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI48994883, Length=236, Percent_Identity=27.1186440677966, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789586, Length=260, Percent_Identity=26.9230769230769, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1786319, Length=204, Percent_Identity=27.9411764705882, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788506, Length=229, Percent_Identity=31.0043668122271, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI48994943, Length=202, Percent_Identity=25.7425742574257, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787500, Length=225, Percent_Identity=26.6666666666667, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1786703, Length=189, Percent_Identity=29.6296296296296, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI87082268, Length=231, Percent_Identity=27.7056277056277, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1790525, Length=245, Percent_Identity=22.8571428571429, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1788897, Length=208, Percent_Identity=28.3653846153846, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1789890, Length=227, Percent_Identity=26.431718061674, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI115533608, Length=221, Percent_Identity=28.5067873303167, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17555800, Length=179, Percent_Identity=27.9329608938547, Blast_Score=81, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17558664, Length=217, Percent_Identity=28.110599078341, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI115533592, Length=219, Percent_Identity=28.310502283105, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71992285, Length=251, Percent_Identity=29.0836653386454, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17510237, Length=182, Percent_Identity=24.7252747252747, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17539902, Length=214, Percent_Identity=28.5046728971963, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17541710, Length=219, Percent_Identity=27.3972602739726, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17511077, Length=198, Percent_Identity=25.2525252525253, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193208177, Length=203, Percent_Identity=26.6009852216749, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6320296, Length=195, Percent_Identity=26.1538461538462, Blast_Score=73, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6322640, Length=202, Percent_Identity=30.1980198019802, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6324498, Length=232, Percent_Identity=24.5689655172414, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI85816269, Length=256, Percent_Identity=25.390625, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24580553, Length=256, Percent_Identity=25.390625, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI85724864, Length=256, Percent_Identity=25.390625, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24580555, Length=256, Percent_Identity=25.390625, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24650855, Length=233, Percent_Identity=28.755364806867, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI281362751, Length=233, Percent_Identity=28.755364806867, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24650853, Length=233, Percent_Identity=28.755364806867, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24581191, Length=184, Percent_Identity=28.804347826087, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24581189, Length=184, Percent_Identity=28.804347826087, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24581193, Length=184, Percent_Identity=28.804347826087, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24581195, Length=184, Percent_Identity=28.804347826087, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI85725262, Length=200, Percent_Identity=29, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24661270, Length=178, Percent_Identity=25.8426966292135, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21355589, Length=178, Percent_Identity=25.8426966292135, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24662800, Length=210, Percent_Identity=28.0952380952381, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI116007184, Length=181, Percent_Identity=27.0718232044199, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221500365, Length=181, Percent_Identity=27.0718232044199, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24582014, Length=221, Percent_Identity=26.6968325791855, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24582012, Length=221, Percent_Identity=26.6968325791855, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI161076682, Length=252, Percent_Identity=24.6031746031746, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI161076684, Length=252, Percent_Identity=24.6031746031746, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24581617, Length=252, Percent_Identity=24.6031746031746, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24581615, Length=252, Percent_Identity=24.6031746031746, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24581387, Length=197, Percent_Identity=30.4568527918782, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28574533, Length=234, Percent_Identity=25.2136752136752, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24581383, Length=197, Percent_Identity=30.4568527918782, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24581385, Length=197, Percent_Identity=30.4568527918782, Blast_Score=68, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: =3.6.3.34 [H]

Molecular weight: Translated: 28945; Mature: 28813

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHWSEPLTDCPQLTLRQLGLHAGSRVLLDGLSMSIGAGQLWCIVGPNGVGKSTLMGVLA
CCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEECCCCCCHHHHHHHHH
GLRAPDSGAAEVDEIAVTQIAPATLARQRAYLPQAVHDTFSMLVEDAVRIGRHPHLSGWG
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
WGQRDDDRIVDDVIDALDLEPLRGRDVLTLSGGERQRVSLAAALAQQAPLLLLDEPVAHL
CCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCEEEECCCHHHH
DLRHQIMVLDLLQRLTRSGRHAVVVIVHDLTLAHRYATHALLMAEDGHALHGPAHEVLTP
HHHHHHHHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHEEEEEECCCCCCCCCHHHHCCH
AQCSHALRTPIISISDGTHTALIPDGNQT
HHHHHHHHCCEEEECCCCEEEEECCCCCC
>Mature Secondary Structure 
SHWSEPLTDCPQLTLRQLGLHAGSRVLLDGLSMSIGAGQLWCIVGPNGVGKSTLMGVLA
CCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEECCCCCCHHHHHHHHH
GLRAPDSGAAEVDEIAVTQIAPATLARQRAYLPQAVHDTFSMLVEDAVRIGRHPHLSGWG
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
WGQRDDDRIVDDVIDALDLEPLRGRDVLTLSGGERQRVSLAAALAQQAPLLLLDEPVAHL
CCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCEEEECCCHHHH
DLRHQIMVLDLLQRLTRSGRHAVVVIVHDLTLAHRYATHALLMAEDGHALHGPAHEVLTP
HHHHHHHHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHEEEEEECCCCCCCCCHHHHCCH
AQCSHALRTPIISISDGTHTALIPDGNQT
HHHHHHHHCCEEEECCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]