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The map label for this gene is cobU [H]

Identifier: 94311711

GI number: 94311711

Start: 3026729

End: 3027373

Strand: Direct

Name: cobU [H]

Synonym: Rmet_2779

Alternate gene names: 94311711

Gene position: 3026729-3027373 (Clockwise)

Preceding gene: 94311708

Following gene: 94311712

Centisome position: 77.05

GC content: 66.82

Gene sequence:

>645_bases
GTGGCCGGCGAGCCGGAAGCCCGGCCCACCCATGAGCCGCACGCGAGCATGTCGATGCCGCGCCAGTTGACGCTCGTGAT
CGGCGGTGCGCGATCGGGCAAGAGCCATTTCGCGGAGCAGCTCGCCACGGACCATGCGGCACTGACACGTGGCCCGGTCA
CCTATATCGCCACGGCGCGCCACGATGTCGATTCCACCGACGAAGAGATGGAATTGCGCATAGCGCTGCATCGCGCGCGC
CGGCCGGCTGACTGGACCCTCGTGGAAGAGCCGGTGCATCTGGCCGACGCGCTCTACGGCCATGCCCGTCACGACGGTTG
CATTCTGGTGGACTGCGTGACGCTGTGGCTCAACAACCTGATCTTCAGCGAAAGCCGCGACTATCCCGAGCACGGTGTCA
TCACGCCGCCACCGGCCTTCACCGAGGAGATCGACGCGCTGATGACCGCGCTGCCGATGCTGCCGGGCCACGTGATCCTC
GTCACCAACGAAATCGGCTTCGGCGTGGTGCCGATGGGCGCCATCACGCGCTTCTATGTCGACGAGCTTGGCCGCCTGAA
CCAGAAGCTCGCCGCGGCCGCCGATCGCGTGCGTCTGCTTGTGGCCGGCATTCCCGTCGCCGTCAAGGACGCGCCCATCG
CATGA

Upstream 100 bases:

>100_bases
ATCGATGCGGACGGCTACAATACGTCGCATGAAGACCAAGGCCATCGCCCAGGCACTCAACATCTCGCCCTCCGCCGAAC
CAGCATCGGCGGGCGCCACC

Downstream 100 bases:

>100_bases
TCATGCTGTCCTGGCCGGCCTGCGTGGCGGCTGCGATCGCCGGCGTTCTGCTGGATCGCTGGCTGGGCGAGCCGCGCCGC
TGGCATCCGCTGGTCGGCTT

Product: bifunctional cobinamide kinase/cobinamide phosphate guanylyltransferase

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 214; Mature: 213

Protein sequence:

>214_residues
MAGEPEARPTHEPHASMSMPRQLTLVIGGARSGKSHFAEQLATDHAALTRGPVTYIATARHDVDSTDEEMELRIALHRAR
RPADWTLVEEPVHLADALYGHARHDGCILVDCVTLWLNNLIFSESRDYPEHGVITPPPAFTEEIDALMTALPMLPGHVIL
VTNEIGFGVVPMGAITRFYVDELGRLNQKLAAAADRVRLLVAGIPVAVKDAPIA

Sequences:

>Translated_214_residues
MAGEPEARPTHEPHASMSMPRQLTLVIGGARSGKSHFAEQLATDHAALTRGPVTYIATARHDVDSTDEEMELRIALHRAR
RPADWTLVEEPVHLADALYGHARHDGCILVDCVTLWLNNLIFSESRDYPEHGVITPPPAFTEEIDALMTALPMLPGHVIL
VTNEIGFGVVPMGAITRFYVDELGRLNQKLAAAADRVRLLVAGIPVAVKDAPIA
>Mature_213_residues
AGEPEARPTHEPHASMSMPRQLTLVIGGARSGKSHFAEQLATDHAALTRGPVTYIATARHDVDSTDEEMELRIALHRARR
PADWTLVEEPVHLADALYGHARHDGCILVDCVTLWLNNLIFSESRDYPEHGVITPPPAFTEEIDALMTALPMLPGHVILV
TNEIGFGVVPMGAITRFYVDELGRLNQKLAAAADRVRLLVAGIPVAVKDAPIA

Specific function: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=189, Percent_Identity=40.2116402116402, Blast_Score=123, Evalue=8e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 23314; Mature: 23183

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGEPEARPTHEPHASMSMPRQLTLVIGGARSGKSHFAEQLATDHAALTRGPVTYIATAR
CCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEEECC
HDVDSTDEEMELRIALHRARRPADWTLVEEPVHLADALYGHARHDGCILVDCVTLWLNNL
CCCCCCCHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHH
IFSESRDYPEHGVITPPPAFTEEIDALMTALPMLPGHVILVTNEIGFGVVPMGAITRFYV
HHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCEECHHHHHHHHH
DELGRLNQKLAAAADRVRLLVAGIPVAVKDAPIA
HHHHHHHHHHHHHHHHHHHHEECCCEEECCCCCC
>Mature Secondary Structure 
AGEPEARPTHEPHASMSMPRQLTLVIGGARSGKSHFAEQLATDHAALTRGPVTYIATAR
CCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEEECC
HDVDSTDEEMELRIALHRARRPADWTLVEEPVHLADALYGHARHDGCILVDCVTLWLNNL
CCCCCCCHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHH
IFSESRDYPEHGVITPPPAFTEEIDALMTALPMLPGHVILVTNEIGFGVVPMGAITRFYV
HHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCEECHHHHHHHHH
DELGRLNQKLAAAADRVRLLVAGIPVAVKDAPIA
HHHHHHHHHHHHHHHHHHHHEECCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]