Click here to switch to the map view.

The map label for this gene is rfbC [H]

Identifier: 94311664

GI number: 94311664

Start: 2968060

End: 2968614

Strand: Reverse

Name: rfbC [H]

Synonym: Rmet_2732

Alternate gene names: 94311664

Gene position: 2968614-2968060 (Counterclockwise)

Preceding gene: 94311665

Following gene: 94311663

Centisome position: 75.57

GC content: 54.59

Gene sequence:

>555_bases
ATGAGTTTGACCGTTACTCGTACCGCCATTCCGGACGTGATGATCATCGAGCCGAAGGTGTTCGGTGATGCCCGGGGGTT
TTTCTTTGAGAGCTTCAATCAGAAGGCGTTTGGGGAAGCTACTGGCCTGGATCTGGAGTTCGTGCAAGACAACCACAGCC
GCAGCGCCAAGGGCGTACTGCGTGGCCTGCACTATCAAATCCAGCAGCCGCAAGGCAAGCTCGTGCGGGTAGTGCGTGGA
CGGGTGTTCGACGTGGCGGTGGATATTCGAAAGCAGTCCGCGACCTTTGGTAAATGGGTTGGCGTGGAGCTCAGCGAAGA
TAATCATCGCCAATTCTGGGTGCCGCCCGGGTTTGCACATGGATTCGTGGTGTTGTCGGAATCTGCTGATTTCCTTTATA
AGACAACTGATTATTACGCTCCGCAGTTCGAGCGGACCATTGCATGGAACGATCCGGAAATCGGCATTGAATGGCCGCAA
ATGAATGTCGTCCCTCTGTTGTCCGCCAAAGATCAGGCAGGCGTGAGTCTTTCCTCGGCTGAACTGTTCGAGTGA

Upstream 100 bases:

>100_bases
GCAAGTGGATTTCCGCCGAGCAGGTTGAGCGTCTGGCGAAGCCACTGCTAAAGAACGCTTACGGCAAGTATCTTCAGCAC
ATCATTTCGGAAACAATCAA

Downstream 100 bases:

>100_bases
CCCCGAATATGGGTTGTCATGCCAGATGGGGGTATTGGATCAGTAGCAATCCGTCATTGGCGAACGGCTGCAAGGCGGCT
ATGGCTGATGGCTGAATCGT

Product: dTDP-4-deoxyrhamnose-3,5-epimerase

Products: NA

Alternate protein names: Thymidine diphospho-4-keto-rhamnose 3,5-epimerase; dTDP-4-keto-6-deoxyglucose 3,5-epimerase; dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 184; Mature: 183

Protein sequence:

>184_residues
MSLTVTRTAIPDVMIIEPKVFGDARGFFFESFNQKAFGEATGLDLEFVQDNHSRSAKGVLRGLHYQIQQPQGKLVRVVRG
RVFDVAVDIRKQSATFGKWVGVELSEDNHRQFWVPPGFAHGFVVLSESADFLYKTTDYYAPQFERTIAWNDPEIGIEWPQ
MNVVPLLSAKDQAGVSLSSAELFE

Sequences:

>Translated_184_residues
MSLTVTRTAIPDVMIIEPKVFGDARGFFFESFNQKAFGEATGLDLEFVQDNHSRSAKGVLRGLHYQIQQPQGKLVRVVRG
RVFDVAVDIRKQSATFGKWVGVELSEDNHRQFWVPPGFAHGFVVLSESADFLYKTTDYYAPQFERTIAWNDPEIGIEWPQ
MNVVPLLSAKDQAGVSLSSAELFE
>Mature_183_residues
SLTVTRTAIPDVMIIEPKVFGDARGFFFESFNQKAFGEATGLDLEFVQDNHSRSAKGVLRGLHYQIQQPQGKLVRVVRGR
VFDVAVDIRKQSATFGKWVGVELSEDNHRQFWVPPGFAHGFVVLSESADFLYKTTDYYAPQFERTIAWNDPEIGIEWPQM
NVVPLLSAKDQAGVSLSSAELFE

Specific function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose [H]

COG id: COG1898

COG function: function code M; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1788350, Length=176, Percent_Identity=59.0909090909091, Blast_Score=212, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI17550412, Length=173, Percent_Identity=50.2890173410405, Blast_Score=158, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR000888
- InterPro:   IPR014710
- ProDom:   PD001462 [H]

Pfam domain/function: PF00908 dTDP_sugar_isom [H]

EC number: =5.1.3.13 [H]

Molecular weight: Translated: 20730; Mature: 20598

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLTVTRTAIPDVMIIEPKVFGDARGFFFESFNQKAFGEATGLDLEFVQDNHSRSAKGVL
CCEEEECCCCCCEEEECCEECCCCCCHHHHHCCCCCCCCCCCCEEEEECCCCCCHHHHHH
RGLHYQIQQPQGKLVRVVRGRVFDVAVDIRKQSATFGKWVGVELSEDNHRQFWVPPGFAH
HHHHEEEECCCHHHHHHHCCEEEEEEEEEECCCCCCCEEEEEEECCCCCEEEECCCCCCC
GFVVLSESADFLYKTTDYYAPQFERTIAWNDPEIGIEWPQMNVVPLLSAKDQAGVSLSSA
EEEEEECCCCEEEEECCCCCCCCCEEEEECCCCCCEECCCCCEEEEECCCCCCCCEECCC
ELFE
CCCC
>Mature Secondary Structure 
SLTVTRTAIPDVMIIEPKVFGDARGFFFESFNQKAFGEATGLDLEFVQDNHSRSAKGVL
CEEEECCCCCCEEEECCEECCCCCCHHHHHCCCCCCCCCCCCEEEEECCCCCCHHHHHH
RGLHYQIQQPQGKLVRVVRGRVFDVAVDIRKQSATFGKWVGVELSEDNHRQFWVPPGFAH
HHHHEEEECCCHHHHHHHCCEEEEEEEEEECCCCCCCEEEEEEECCCCCEEEECCCCCCC
GFVVLSESADFLYKTTDYYAPQFERTIAWNDPEIGIEWPQMNVVPLLSAKDQAGVSLSSA
EEEEEECCCCEEEEECCCCCCCCCEEEEECCCCCCEECCCCCEEEEECCCCCCCCEECCC
ELFE
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]