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The map label for this gene is 94311439

Identifier: 94311439

GI number: 94311439

Start: 2716925

End: 2718700

Strand: Reverse

Name: 94311439

Synonym: Rmet_2503

Alternate gene names: NA

Gene position: 2718700-2716925 (Counterclockwise)

Preceding gene: 94311440

Following gene: 94311438

Centisome position: 69.21

GC content: 62.67

Gene sequence:

>1776_bases
ATGGCGATCAAGAAGGACAAGGTCGATTGCGTGGTGATCGGTCTCGGCTGGACTGGCGCGATTCTCGCCCAGGAGCTGAC
CGACGCGGGGCTCGACGTCGTGGCGCTCGAACGTGGCGCGATGCGCGATACCCCGACCGATGCCGAGTATCCGAAAGTCG
TCGACGAACTGAAGTACGTCGTGCGCGGAGAGCTGTTTCAGGATCTCTCCCGGGAGACGGTCACGATCCGTCACGGCGTG
GATGACCTGGCGGTGCCGTATCGGCAAAACGGCTCGTTCCTGCTTGGCAATGGCGTGGGTGGCGCGGGCTTTCACTGGAA
CGGGATGCACTATCGCGTCCTGCCGGAAGAACTGCAGTTGCGCAGCCGCTACGTGGATCGCTATGGCAAGAAGTTCATTC
CCGAAGGGATGCAGGTGCAGGACTTCGGTGTCACGTACGACGAACTCGAGCCACACTTCGACTTCGCAGAGAAAGTGTTT
GGCACCTCGGGCACGGCCGGCAACCTGAATGGCAAGATCCAGCCGGGCGGCAATCCGCTCGAAGGCCACCGGTCGAGCGA
GTACCCGACCCCGGCGCTGAAGAATTCGCTCGGCGCGCAATTGTTCGAAAAGGCCGCGCGCGAGGCGGGCTTCCACCCGT
ACCCGGCACCGGCGGCGAATACGTCCGAGCCCTATACGAACCCCTACGGCGTGCGCCTTGGGCCGTGCAATTTCTGCGGC
TTCTGCGAGGACTTCGGCTGCTACATGTATTCGAAGGCGTCACCGCAGACGACGATCCTGCCGGTCCTGCTGAAGAAACC
CAACTTCGAGTTGCGCACGAAGGCGCAAGTCACCAGGATCCTGCTCGATTCCGACAAGAAGCGCGCGACCGGCGTGCTGT
ACATCGACGCCCAGGGGCGAGAGGTCGAGCAACCCGCCGATCTCGTGATCGTCGCGGCGTACCAGTTGCACAACGTGCGT
CTGCTGTTGCTCTCCGGCATCGGCACGCCGTATGACCCGAAAACCGGCAAGGGTGTCGTTGGCCGCAACTACGCGTATCA
GATGAACGGCGCGGTCAACGTGATGCTGCCCAAGGGCACGCTGCTTAATCCGTTCATCGGGACGGGTGCCGGCGGGGTAG
GGCTGGATGACCTGAATGGCGACCAGTTCGATCATGGTCCGCTCGGCTTTCTCGGCGGGGCGAGTATTCGCCATATACGT
TATGGCGGCCGGCCCATCAAGCAGACGCCGACTGTCCCCGGCACGCCAGCGTGGGGCAGCAAGTGGAAGGCGGGAGTGGT
CGATGCGTACCAGCGCTATATGACGATCGGCATTTCGGGCTCGGTCATGCCGTATCGCGATGCGTACCTCGATCTCGATC
CGACGTACCGCGACGCCAACGGCCTGCCGCTGATGCGCATGACCTTCGACTGGCACGACAACGAGTACGCCATGCTGGAT
TACATGGGCACCCGCATGGAAGAGGTGGCCAAGGCGATGAAGCCCGAGGCGTACTACAAGGCCATCCGCAAGAAGGGCCA
GCACTACGACACGCGCGTCTATCAGTCCACGCACACGACAGGCGGCGCCGTGATGGGATCGTCGCCCGAGACCAGCGTGG
TCAACAAGTATCTGCAGAGCTGGGATGTACACAACGTGTTCGTCATGGGCGCCTCGGCGTTCCCGCAGAACATGGGCTAC
AACCCGACCGGTCTGGTAGCCGCGCTTGCCTATCACTCCGCGAAGGCTATCCGCGAGCAGTACTTGAAGCACCCGGCGCC
GCTGGTTCAGGCTTGA

Upstream 100 bases:

>100_bases
GTTTCCCCGGCGCACGGGCGGATTTCGCGGACTGGATCGATCAGCCAGGGGTGAAGTATCCCTATGGTCCGGTGTCGATC
GACGGACGGAGGGGATAAGC

Downstream 100 bases:

>100_bases
GGTGATGGCCATGAAAGCAAGCAAGAAAGCAACAATGATGGTGGCGGCGTCGGCGCTGCTGGCGGCGTCGGCGTGGACCA
TCGGTGCGTTCGCCGATGAC

Product: gluconate 2-dehydrogenase flavoprotein

Products: NA

Alternate protein names: GA 2-DH dehydrogenase subunit; GADH dehydrogenase subunit [H]

Number of amino acids: Translated: 591; Mature: 590

Protein sequence:

>591_residues
MAIKKDKVDCVVIGLGWTGAILAQELTDAGLDVVALERGAMRDTPTDAEYPKVVDELKYVVRGELFQDLSRETVTIRHGV
DDLAVPYRQNGSFLLGNGVGGAGFHWNGMHYRVLPEELQLRSRYVDRYGKKFIPEGMQVQDFGVTYDELEPHFDFAEKVF
GTSGTAGNLNGKIQPGGNPLEGHRSSEYPTPALKNSLGAQLFEKAAREAGFHPYPAPAANTSEPYTNPYGVRLGPCNFCG
FCEDFGCYMYSKASPQTTILPVLLKKPNFELRTKAQVTRILLDSDKKRATGVLYIDAQGREVEQPADLVIVAAYQLHNVR
LLLLSGIGTPYDPKTGKGVVGRNYAYQMNGAVNVMLPKGTLLNPFIGTGAGGVGLDDLNGDQFDHGPLGFLGGASIRHIR
YGGRPIKQTPTVPGTPAWGSKWKAGVVDAYQRYMTIGISGSVMPYRDAYLDLDPTYRDANGLPLMRMTFDWHDNEYAMLD
YMGTRMEEVAKAMKPEAYYKAIRKKGQHYDTRVYQSTHTTGGAVMGSSPETSVVNKYLQSWDVHNVFVMGASAFPQNMGY
NPTGLVAALAYHSAKAIREQYLKHPAPLVQA

Sequences:

>Translated_591_residues
MAIKKDKVDCVVIGLGWTGAILAQELTDAGLDVVALERGAMRDTPTDAEYPKVVDELKYVVRGELFQDLSRETVTIRHGV
DDLAVPYRQNGSFLLGNGVGGAGFHWNGMHYRVLPEELQLRSRYVDRYGKKFIPEGMQVQDFGVTYDELEPHFDFAEKVF
GTSGTAGNLNGKIQPGGNPLEGHRSSEYPTPALKNSLGAQLFEKAAREAGFHPYPAPAANTSEPYTNPYGVRLGPCNFCG
FCEDFGCYMYSKASPQTTILPVLLKKPNFELRTKAQVTRILLDSDKKRATGVLYIDAQGREVEQPADLVIVAAYQLHNVR
LLLLSGIGTPYDPKTGKGVVGRNYAYQMNGAVNVMLPKGTLLNPFIGTGAGGVGLDDLNGDQFDHGPLGFLGGASIRHIR
YGGRPIKQTPTVPGTPAWGSKWKAGVVDAYQRYMTIGISGSVMPYRDAYLDLDPTYRDANGLPLMRMTFDWHDNEYAMLD
YMGTRMEEVAKAMKPEAYYKAIRKKGQHYDTRVYQSTHTTGGAVMGSSPETSVVNKYLQSWDVHNVFVMGASAFPQNMGY
NPTGLVAALAYHSAKAIREQYLKHPAPLVQA
>Mature_590_residues
AIKKDKVDCVVIGLGWTGAILAQELTDAGLDVVALERGAMRDTPTDAEYPKVVDELKYVVRGELFQDLSRETVTIRHGVD
DLAVPYRQNGSFLLGNGVGGAGFHWNGMHYRVLPEELQLRSRYVDRYGKKFIPEGMQVQDFGVTYDELEPHFDFAEKVFG
TSGTAGNLNGKIQPGGNPLEGHRSSEYPTPALKNSLGAQLFEKAAREAGFHPYPAPAANTSEPYTNPYGVRLGPCNFCGF
CEDFGCYMYSKASPQTTILPVLLKKPNFELRTKAQVTRILLDSDKKRATGVLYIDAQGREVEQPADLVIVAAYQLHNVRL
LLLSGIGTPYDPKTGKGVVGRNYAYQMNGAVNVMLPKGTLLNPFIGTGAGGVGLDDLNGDQFDHGPLGFLGGASIRHIRY
GGRPIKQTPTVPGTPAWGSKWKAGVVDAYQRYMTIGISGSVMPYRDAYLDLDPTYRDANGLPLMRMTFDWHDNEYAMLDY
MGTRMEEVAKAMKPEAYYKAIRKKGQHYDTRVYQSTHTTGGAVMGSSPETSVVNKYLQSWDVHNVFVMGASAFPQNMGYN
PTGLVAALAYHSAKAIREQYLKHPAPLVQA

Specific function: Part of the heterotrimer that catalyzes the conversion of D-gluconate to 2-dehydro-D-gluconate. This subunit functions as the dehydrogenase [H]

COG id: COG2303

COG function: function code E; Choline dehydrogenase and related flavoproteins

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GMC oxidoreductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000172
- InterPro:   IPR007867 [H]

Pfam domain/function: PF05199 GMC_oxred_C; PF00732 GMC_oxred_N [H]

EC number: =1.1.99.3 [H]

Molecular weight: Translated: 64967; Mature: 64835

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIKKDKVDCVVIGLGWTGAILAQELTDAGLDVVALERGAMRDTPTDAEYPKVVDELKYV
CCCCCCCCCEEEEECCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHH
VRGELFQDLSRETVTIRHGVDDLAVPYRQNGSFLLGNGVGGAGFHWNGMHYRVLPEELQL
HHHHHHHHCCCCEEEEECCCCHHCCCEECCCCEEEECCCCCCCEEECCEEEEECHHHHHH
RSRYVDRYGKKFIPEGMQVQDFGVTYDELEPHFDFAEKVFGTSGTAGNLNGKIQPGGNPL
HHHHHHHHHHHHCCCCCEEEECCCCHHHCCCCHHHHHHHHCCCCCCCCCCCEECCCCCCC
EGHRSSEYPTPALKNSLGAQLFEKAAREAGFHPYPAPAANTSEPYTNPYGVRLGPCNFCG
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCC
FCEDFGCYMYSKASPQTTILPVLLKKPNFELRTKAQVTRILLDSDKKRATGVLYIDAQGR
CHHHHCCEEEECCCCCCEEEEEEECCCCCCEEHHHHHHHHHHCCCCCCCCEEEEEECCCC
EVEQPADLVIVAAYQLHNVRLLLLSGIGTPYDPKTGKGVVGRNYAYQMNGAVNVMLPKGT
CCCCCCCEEEEEEEECCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEECCEEEEEECCCC
LLNPFIGTGAGGVGLDDLNGDQFDHGPLGFLGGASIRHIRYGGRPIKQTPTVPGTPAWGS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCC
KWKAGVVDAYQRYMTIGISGSVMPYRDAYLDLDPTYRDANGLPLMRMTFDWHDNEYAMLD
CCCCHHHHHHHHHEEEECCCCCCCCCCCEEECCCCCCCCCCCEEEEEEEEECCCCEEEEH
YMGTRMEEVAKAMKPEAYYKAIRKKGQHYDTRVYQSTHTTGGAVMGSSPETSVVNKYLQS
HHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHEEECCCCCCCEEECCCCCHHHHHHHHHC
WDVHNVFVMGASAFPQNMGYNPTGLVAALAYHSAKAIREQYLKHPAPLVQA
CCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AIKKDKVDCVVIGLGWTGAILAQELTDAGLDVVALERGAMRDTPTDAEYPKVVDELKYV
CCCCCCCCEEEEECCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHH
VRGELFQDLSRETVTIRHGVDDLAVPYRQNGSFLLGNGVGGAGFHWNGMHYRVLPEELQL
HHHHHHHHCCCCEEEEECCCCHHCCCEECCCCEEEECCCCCCCEEECCEEEEECHHHHHH
RSRYVDRYGKKFIPEGMQVQDFGVTYDELEPHFDFAEKVFGTSGTAGNLNGKIQPGGNPL
HHHHHHHHHHHHCCCCCEEEECCCCHHHCCCCHHHHHHHHCCCCCCCCCCCEECCCCCCC
EGHRSSEYPTPALKNSLGAQLFEKAAREAGFHPYPAPAANTSEPYTNPYGVRLGPCNFCG
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCC
FCEDFGCYMYSKASPQTTILPVLLKKPNFELRTKAQVTRILLDSDKKRATGVLYIDAQGR
CHHHHCCEEEECCCCCCEEEEEEECCCCCCEEHHHHHHHHHHCCCCCCCCEEEEEECCCC
EVEQPADLVIVAAYQLHNVRLLLLSGIGTPYDPKTGKGVVGRNYAYQMNGAVNVMLPKGT
CCCCCCCEEEEEEEECCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEECCEEEEEECCCC
LLNPFIGTGAGGVGLDDLNGDQFDHGPLGFLGGASIRHIRYGGRPIKQTPTVPGTPAWGS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCC
KWKAGVVDAYQRYMTIGISGSVMPYRDAYLDLDPTYRDANGLPLMRMTFDWHDNEYAMLD
CCCCHHHHHHHHHEEEECCCCCCCCCCCEEECCCCCCCCCCCEEEEEEEEECCCCEEEEH
YMGTRMEEVAKAMKPEAYYKAIRKKGQHYDTRVYQSTHTTGGAVMGSSPETSVVNKYLQS
HHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHEEECCCCCCCEEECCCCCHHHHHHHHHC
WDVHNVFVMGASAFPQNMGYNPTGLVAALAYHSAKAIREQYLKHPAPLVQA
CCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9352901 [H]