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The map label for this gene is trxB2 [C]

Identifier: 94311388

GI number: 94311388

Start: 2663304

End: 2664407

Strand: Direct

Name: trxB2 [C]

Synonym: Rmet_2452

Alternate gene names: 94311388

Gene position: 2663304-2664407 (Clockwise)

Preceding gene: 94311387

Following gene: 94311389

Centisome position: 67.8

GC content: 62.41

Gene sequence:

>1104_bases
ATGGACTTGAGCATTCCTAACCCCGTGGCCGACGCGACCCATCAGGCCGGCGGGAACCCTGGCGGTCAGCCGCTGGAAAT
TGACGCGCTGATCGTGGGCGCTGGCCCGGTCGGCCTGTTCCAGGTCTTTGAACTGGGGCTGCTCGAAATCAAGGCACACA
TCATCGACTCGCTCAAGGTAGTGGGCGGCCAGTGCGTCGAGCTGTATCCGGACAAGCCGATCTACGATATCCCGGCCGTG
CCCATCTGCACGGGCCAGGAACTGACCGACAACCTGCTGAAGCAGATCGAGCCGTTCTCGCCGACGTTCCATCTGGGTCA
GGAAGTGAGCGTCGTGGAGCGCCGCGAAGACGGCCGCTTCTTCGTCGAAACATCGCTTGGAACCCGCTTCATCACCAAGA
CCATCTTCATCGCCGCCGGCGTTGGCTCGTTCCAGCCGCGCACGCTGAAGGTGGAAGGCATCGACAAGTTCGAAGGAAAG
CAGCTGTTCTACCGCGTCAAGGATCCGAGCCGCTTCCACGGCCGCAATCTGGTCGTCGTCGGCGGTGGTGATTCGGCGCT
GGACTGGACGCTGGATCTGGTGGGCAAGGCCGAGTCGGTGGTGATGATCCACCGCCGCGATGGTTTCCGTGCCGCACCGG
CATCGGTGGCCAAGATGCGCGAGCTGTGCGAGCAGATGGAAATGCAATTCATGGTCGGCCAGATCGGCGGCTATGAAGAG
AAGGATGGCGTGCTCACCGAGATCAAGGTGACCGGCGCCGACGGCGTGACCCGCCGTATGCCCGTCGACGACATCCTCGT
GTTCTTCGGCCTTTCGCCGAAGCTCGGCCCGATCGCCGAATGGGGCCTGGACCTCGAGCGCAAGCAGATCAAGGTGGACA
CCGAGAAGTTCGAGACGAACATCCCGGGCATCTTCGCGGTTGGCGACATCAACACCTACCCGGGCAAGAAGAAGCTGATC
CTGTCGGGCTTCCACGAAGCCGCGCTGGCTGCTTTCGGCGCCGCGCCGTACATCTTCCCGGACAAGAAGATCCACATGCA
GTACACGACGACCTCGCCGAAGCTGCACAAGGTGCTTGGCGTGGAGACGCCGGTTTTCGACTGA

Upstream 100 bases:

>100_bases
AAGCTGCAATACCTGCAGCGCTAAAAAAATACAGAGAGCCGTCCCCCGCGCTTTCTAGCAATGCCGGGCACATGTGTGCC
CACAACGTATCAGGACGAAT

Downstream 100 bases:

>100_bases
GATCGGAACCGAAACAAAAAAGCCGCCTCCGGGCGGTTTTTTGTTTGCATAAATCGAAAAGCTGGCTATAATGCGGCCTC
GCTGCTAAACACGGCAACGC

Product: thioredoxin reductase

Products: NA

Alternate protein names: FNR 2; Fd-NADP+ reductase 2 [H]

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MDLSIPNPVADATHQAGGNPGGQPLEIDALIVGAGPVGLFQVFELGLLEIKAHIIDSLKVVGGQCVELYPDKPIYDIPAV
PICTGQELTDNLLKQIEPFSPTFHLGQEVSVVERREDGRFFVETSLGTRFITKTIFIAAGVGSFQPRTLKVEGIDKFEGK
QLFYRVKDPSRFHGRNLVVVGGGDSALDWTLDLVGKAESVVMIHRRDGFRAAPASVAKMRELCEQMEMQFMVGQIGGYEE
KDGVLTEIKVTGADGVTRRMPVDDILVFFGLSPKLGPIAEWGLDLERKQIKVDTEKFETNIPGIFAVGDINTYPGKKKLI
LSGFHEAALAAFGAAPYIFPDKKIHMQYTTTSPKLHKVLGVETPVFD

Sequences:

>Translated_367_residues
MDLSIPNPVADATHQAGGNPGGQPLEIDALIVGAGPVGLFQVFELGLLEIKAHIIDSLKVVGGQCVELYPDKPIYDIPAV
PICTGQELTDNLLKQIEPFSPTFHLGQEVSVVERREDGRFFVETSLGTRFITKTIFIAAGVGSFQPRTLKVEGIDKFEGK
QLFYRVKDPSRFHGRNLVVVGGGDSALDWTLDLVGKAESVVMIHRRDGFRAAPASVAKMRELCEQMEMQFMVGQIGGYEE
KDGVLTEIKVTGADGVTRRMPVDDILVFFGLSPKLGPIAEWGLDLERKQIKVDTEKFETNIPGIFAVGDINTYPGKKKLI
LSGFHEAALAAFGAAPYIFPDKKIHMQYTTTSPKLHKVLGVETPVFD
>Mature_367_residues
MDLSIPNPVADATHQAGGNPGGQPLEIDALIVGAGPVGLFQVFELGLLEIKAHIIDSLKVVGGQCVELYPDKPIYDIPAV
PICTGQELTDNLLKQIEPFSPTFHLGQEVSVVERREDGRFFVETSLGTRFITKTIFIAAGVGSFQPRTLKVEGIDKFEGK
QLFYRVKDPSRFHGRNLVVVGGGDSALDWTLDLVGKAESVVMIHRRDGFRAAPASVAKMRELCEQMEMQFMVGQIGGYEE
KDGVLTEIKVTGADGVTRRMPVDDILVFFGLSPKLGPIAEWGLDLERKQIKVDTEKFETNIPGIFAVGDINTYPGKKKLI
LSGFHEAALAAFGAAPYIFPDKKIHMQYTTTSPKLHKVLGVETPVFD

Specific function: Serves To Protect The Cell Against DNA Damage By Alkyl Hydroperoxides. It Can Use Either NADH Or NADPH As Electron Donor For Direct Reduction Of Redox Dyes Or Of Alkyl Hydroperoxides When Combined With The Ahpc Protein. [C]

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ferredoxin--NADP reductase type 2 family [H]

Homologues:

Organism=Escherichia coli, GI87081763, Length=292, Percent_Identity=26.027397260274, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1787114, Length=222, Percent_Identity=27.027027027027, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR022890
- InterPro:   IPR001327
- InterPro:   IPR000103 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.18.1.2 [H]

Molecular weight: Translated: 40153; Mature: 40153

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLSIPNPVADATHQAGGNPGGQPLEIDALIVGAGPVGLFQVFELGLLEIKAHIIDSLKV
CCCCCCCCHHHHHHHCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
VGGQCVELYPDKPIYDIPAVPICTGQELTDNLLKQIEPFSPTFHLGQEVSVVERREDGRF
CCCEEEEECCCCCCCCCCCCCEECCHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCE
FVETSLGTRFITKTIFIAAGVGSFQPRTLKVEGIDKFEGKQLFYRVKDPSRFHGRNLVVV
EEEECCCCHHHHHEEEEEECCCCCCCCEEEEECCCCCCCCEEEEEECCCCCCCCCEEEEE
GGGDSALDWTLDLVGKAESVVMIHRRDGFRAAPASVAKMRELCEQMEMQFMVGQIGGYEE
CCCCCCEEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
KDGVLTEIKVTGADGVTRRMPVDDILVFFGLSPKLGPIAEWGLDLERKQIKVDTEKFETN
CCCEEEEEEEECCCCCCCCCCHHHHHEEECCCCCCCCHHHHCCCCCCCEEEEEHHHHHCC
IPGIFAVGDINTYPGKKKLILSGFHEAALAAFGAAPYIFPDKKIHMQYTTTSPKLHKVLG
CCCEEEECCCCCCCCCCEEEEECHHHHHHHHHCCCCEECCCCEEEEEEECCCCHHHHHHC
VETPVFD
CCCCCCC
>Mature Secondary Structure
MDLSIPNPVADATHQAGGNPGGQPLEIDALIVGAGPVGLFQVFELGLLEIKAHIIDSLKV
CCCCCCCCHHHHHHHCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
VGGQCVELYPDKPIYDIPAVPICTGQELTDNLLKQIEPFSPTFHLGQEVSVVERREDGRF
CCCEEEEECCCCCCCCCCCCCEECCHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCE
FVETSLGTRFITKTIFIAAGVGSFQPRTLKVEGIDKFEGKQLFYRVKDPSRFHGRNLVVV
EEEECCCCHHHHHEEEEEECCCCCCCCEEEEECCCCCCCCEEEEEECCCCCCCCCEEEEE
GGGDSALDWTLDLVGKAESVVMIHRRDGFRAAPASVAKMRELCEQMEMQFMVGQIGGYEE
CCCCCCEEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
KDGVLTEIKVTGADGVTRRMPVDDILVFFGLSPKLGPIAEWGLDLERKQIKVDTEKFETN
CCCEEEEEEEECCCCCCCCCCHHHHHEEECCCCCCCCHHHHCCCCCCCEEEEEHHHHHCC
IPGIFAVGDINTYPGKKKLILSGFHEAALAAFGAAPYIFPDKKIHMQYTTTSPKLHKVLG
CCCEEEECCCCCCCCCCEEEEECHHHHHHHHHCCCCEECCCCEEEEEEECCCCHHHHHHC
VETPVFD
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA