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The map label for this gene is nagZ [H]

Identifier: 94311349

GI number: 94311349

Start: 2623456

End: 2624505

Strand: Reverse

Name: nagZ [H]

Synonym: Rmet_2413

Alternate gene names: 94311349

Gene position: 2624505-2623456 (Counterclockwise)

Preceding gene: 94311350

Following gene: 94311346

Centisome position: 66.81

GC content: 63.62

Gene sequence:

>1050_bases
ATGAACAAGAAAGTCTCCGGCAAGCGGCCGGGCCCGGTAGTGCTCGACGTCGTGGGCAAGGAACTCACCGCCGACGATGC
GCGTCGCATTGCCCACCCGTTGACGGGTGGCGTGATCCTGTTTGCGCGCAACTTCGAATCGCGCGCGCAACTGGTGGCGC
TGACGCGGGCCATTCGTGAAGTCCGCGACGATGCGCTCATCTGCATCGACCATGAAGGTGGCCGCGTGCAGCGCGCCAAA
ACCGATGGCTTCACGCACCTGCCGGCGATGTCCCGGCTTGGGGCGCTGTGGGACCGTGACGTGCTGGCTGCCACCAAAGT
GGCGATGGCTTGCGGCTACGTGCTGGCGGCCGAACTGCGTGCATGCGACATCGACCTGAGCTTCACCCCGGTGCTAGACC
TCGACTATGGCCGCAGTGGTGTCATTGGCGATCGTGCGTTCCATGCCGATCCTCGTGTAGTGACCATGCTGGCCAACCAT
CTGACGCACGGACTGCTGCTGGCCGGCATGGCCAACTGCGGCAAGCACTTCCCGGGGCATGGCTATGTCGAAGCCGATTC
GCATGTGGCCATTCCGGTGGACGAGCGCGGTCTTGATGAAATCCTGTCCCAGGACGCCCGTCCCTATGACTGGATGGGCC
CGGCGCTAGCGTCTGTGATGCCTGCCCACGTGATCTACCCGACCGTCGATCCGAGCCCTGCGGGCTTCTCGCGCTACTGG
CTGCAGGACATCCTGCGGACCCAGCTTGGTTTTGAGGGCGTGATTTTCAGTGACGACCTCAGCATGGAGGGCGCGAGCGT
GGCCGGTACCGTTACCCAGGCCGCACGTGCCGCGCTCGAGGCGGGTTGCGACATGGTGTTGATCTGCAACCATCCGGATC
GCGCGGACCAGCTTTTGAATGAACTCGATGTGTCGATCGGCAAGGCCTCGCAGCGGCGCATCCGCAAGCTGTTCGGTCGC
CGCAAGCCGCTGGACTGGAACAAGTTGCAGCAAGAAGGCGAATACCGCGCCGCGCTGCGCCTGCTGAAGGAACACGATCT
TATCGCTTGA

Upstream 100 bases:

>100_bases
ACGAACATGAATATGCGGTCGCGTTCGCGATCGCCGAGCGGGGTGGTCAGCTGGCGGCCCCGCAATCCGAACCCGCTTCG
AACTGAATTCGATATTCGAT

Downstream 100 bases:

>100_bases
GCGACTCCGGCCGCCGGGTGGTGAATCGACACCACCCAGACATGAATCAGCAGGAATGGATCCGTGGAAAGAAAAAGGGC
AGCCGAAGCTGCCCTTTTTT

Product: beta-hexosaminidase

Products: NA

Alternate protein names: Beta-N-acetylhexosaminidase; N-acetyl-beta-glucosaminidase [H]

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MNKKVSGKRPGPVVLDVVGKELTADDARRIAHPLTGGVILFARNFESRAQLVALTRAIREVRDDALICIDHEGGRVQRAK
TDGFTHLPAMSRLGALWDRDVLAATKVAMACGYVLAAELRACDIDLSFTPVLDLDYGRSGVIGDRAFHADPRVVTMLANH
LTHGLLLAGMANCGKHFPGHGYVEADSHVAIPVDERGLDEILSQDARPYDWMGPALASVMPAHVIYPTVDPSPAGFSRYW
LQDILRTQLGFEGVIFSDDLSMEGASVAGTVTQAARAALEAGCDMVLICNHPDRADQLLNELDVSIGKASQRRIRKLFGR
RKPLDWNKLQQEGEYRAALRLLKEHDLIA

Sequences:

>Translated_349_residues
MNKKVSGKRPGPVVLDVVGKELTADDARRIAHPLTGGVILFARNFESRAQLVALTRAIREVRDDALICIDHEGGRVQRAK
TDGFTHLPAMSRLGALWDRDVLAATKVAMACGYVLAAELRACDIDLSFTPVLDLDYGRSGVIGDRAFHADPRVVTMLANH
LTHGLLLAGMANCGKHFPGHGYVEADSHVAIPVDERGLDEILSQDARPYDWMGPALASVMPAHVIYPTVDPSPAGFSRYW
LQDILRTQLGFEGVIFSDDLSMEGASVAGTVTQAARAALEAGCDMVLICNHPDRADQLLNELDVSIGKASQRRIRKLFGR
RKPLDWNKLQQEGEYRAALRLLKEHDLIA
>Mature_349_residues
MNKKVSGKRPGPVVLDVVGKELTADDARRIAHPLTGGVILFARNFESRAQLVALTRAIREVRDDALICIDHEGGRVQRAK
TDGFTHLPAMSRLGALWDRDVLAATKVAMACGYVLAAELRACDIDLSFTPVLDLDYGRSGVIGDRAFHADPRVVTMLANH
LTHGLLLAGMANCGKHFPGHGYVEADSHVAIPVDERGLDEILSQDARPYDWMGPALASVMPAHVIYPTVDPSPAGFSRYW
LQDILRTQLGFEGVIFSDDLSMEGASVAGTVTQAARAALEAGCDMVLICNHPDRADQLLNELDVSIGKASQRRIRKLFGR
RKPLDWNKLQQEGEYRAALRLLKEHDLIA

Specific function: Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides [H]

COG id: COG1472

COG function: function code G; Beta-glucosidase-related glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787350, Length=319, Percent_Identity=45.141065830721, Blast_Score=265, Evalue=3e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022956
- InterPro:   IPR019800
- InterPro:   IPR001764
- InterPro:   IPR017853 [H]

Pfam domain/function: PF00933 Glyco_hydro_3 [H]

EC number: =3.2.1.52 [H]

Molecular weight: Translated: 38187; Mature: 38187

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00775 GLYCOSYL_HYDROL_F3 ; PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKVSGKRPGPVVLDVVGKELTADDARRIAHPLTGGVILFARNFESRAQLVALTRAIRE
CCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHH
VRDDALICIDHEGGRVQRAKTDGFTHLPAMSRLGALWDRDVLAATKVAMACGYVLAAELR
HCCCEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
ACDIDLSFTPVLDLDYGRSGVIGDRAFHADPRVVTMLANHLTHGLLLAGMANCGKHFPGH
HEECCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GYVEADSHVAIPVDERGLDEILSQDARPYDWMGPALASVMPAHVIYPTVDPSPAGFSRYW
CEEECCCEEEECCCCCCHHHHHHCCCCCCCCCCHHHHHHCCHHEEECCCCCCCCCHHHHH
LQDILRTQLGFEGVIFSDDLSMEGASVAGTVTQAARAALEAGCDMVLICNHPDRADQLLN
HHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHH
ELDVSIGKASQRRIRKLFGRRKPLDWNKLQQEGEYRAALRLLKEHDLIA
HHHHHHCHHHHHHHHHHHCCCCCCCHHHHHHCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNKKVSGKRPGPVVLDVVGKELTADDARRIAHPLTGGVILFARNFESRAQLVALTRAIRE
CCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHH
VRDDALICIDHEGGRVQRAKTDGFTHLPAMSRLGALWDRDVLAATKVAMACGYVLAAELR
HCCCEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
ACDIDLSFTPVLDLDYGRSGVIGDRAFHADPRVVTMLANHLTHGLLLAGMANCGKHFPGH
HEECCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GYVEADSHVAIPVDERGLDEILSQDARPYDWMGPALASVMPAHVIYPTVDPSPAGFSRYW
CEEECCCEEEECCCCCCHHHHHHCCCCCCCCCCHHHHHHCCHHEEECCCCCCCCCHHHHH
LQDILRTQLGFEGVIFSDDLSMEGASVAGTVTQAARAALEAGCDMVLICNHPDRADQLLN
HHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHH
ELDVSIGKASQRRIRKLFGRRKPLDWNKLQQEGEYRAALRLLKEHDLIA
HHHHHHCHHHHHHHHHHHCCCCCCCHHHHHHCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA