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The map label for this gene is acpS

Identifier: 94311350

GI number: 94311350

Start: 2624520

End: 2624951

Strand: Reverse

Name: acpS

Synonym: Rmet_2414

Alternate gene names: 94311350

Gene position: 2624951-2624520 (Counterclockwise)

Preceding gene: 94311351

Following gene: 94311349

Centisome position: 66.83

GC content: 63.89

Gene sequence:

>432_bases
GTGATCTACGGCGTCGGCACCGACATCATCCAGATTGATCGCGTGCGCGGCGTGATGGAGCGCACGCGTGGGCGCTTTGT
CGAGAAGATTCTCGGGCCGCGTGAGATGAAGATCTATCTTGCACGCAAGGCGCGCTCGGAAAAGCGCGGCTTGGCATTCC
TGTGCACGCGTTTCGCGGCCAAGGAGGCATTCTCGAAGGCCATCGGCCTGGGGATGCGCTGGCCGATGACGTGGCGTGCG
ATGGAACTGCTGAACCAGCCATCGGGCGAGCCCGCGCCGCATTGCACTGGCGAACTGGCGGAATGGGTGCGGGAACGCGG
CCTGACCGTTCGTGTCAGTGTCAGTGACGAACATGAATATGCGGTCGCGTTCGCGATCGCCGAGCGGGGTGGTCAGCTGG
CGGCCCCGCAATCCGAACCCGCTTCGAACTGA

Upstream 100 bases:

>100_bases
ATGCGGTGTTTGCCGGGTGGCAGAACGCCGTGCGCGAGATGAAGGCCATCATGGTGGCGGCGCGCCTCGGTACCCGTTAC
CCGGTTCCGGGTCAGCCCGC

Downstream 100 bases:

>100_bases
ATTCGATATTCGATATGAACAAGAAAGTCTCCGGCAAGCGGCCGGGCCCGGTAGTGCTCGACGTCGTGGGCAAGGAACTC
ACCGCCGACGATGCGCGTCG

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 143; Mature: 143

Protein sequence:

>143_residues
MIYGVGTDIIQIDRVRGVMERTRGRFVEKILGPREMKIYLARKARSEKRGLAFLCTRFAAKEAFSKAIGLGMRWPMTWRA
MELLNQPSGEPAPHCTGELAEWVRERGLTVRVSVSDEHEYAVAFAIAERGGQLAAPQSEPASN

Sequences:

>Translated_143_residues
MIYGVGTDIIQIDRVRGVMERTRGRFVEKILGPREMKIYLARKARSEKRGLAFLCTRFAAKEAFSKAIGLGMRWPMTWRA
MELLNQPSGEPAPHCTGELAEWVRERGLTVRVSVSDEHEYAVAFAIAERGGQLAAPQSEPASN
>Mature_143_residues
MIYGVGTDIIQIDRVRGVMERTRGRFVEKILGPREMKIYLARKARSEKRGLAFLCTRFAAKEAFSKAIGLGMRWPMTWRA
MELLNQPSGEPAPHCTGELAEWVRERGLTVRVSVSDEHEYAVAFAIAERGGQLAAPQSEPASN

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=128, Percent_Identity=32.8125, Blast_Score=71, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_RALME (Q1LKN5)

Other databases:

- EMBL:   CP000352
- RefSeq:   YP_584560.1
- ProteinModelPortal:   Q1LKN5
- SMR:   Q1LKN5
- STRING:   Q1LKN5
- GeneID:   4039236
- GenomeReviews:   CP000352_GR
- KEGG:   rme:Rmet_2414
- eggNOG:   NOG129113
- HOGENOM:   HBG734479
- OMA:   QGVFWRD
- PhylomeDB:   Q1LKN5
- ProtClustDB:   PRK00070
- BioCyc:   RMET266264:RMET_2414-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 16007; Mature: 16007

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYGVGTDIIQIDRVRGVMERTRGRFVEKILGPREMKIYLARKARSEKRGLAFLCTRFAA
CEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHCCHHHHHHHHHH
KEAFSKAIGLGMRWPMTWRAMELLNQPSGEPAPHCTGELAEWVRERGLTVRVSVSDEHEY
HHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCEEEEEECCCCCH
AVAFAIAERGGQLAAPQSEPASN
HHHHEEHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIYGVGTDIIQIDRVRGVMERTRGRFVEKILGPREMKIYLARKARSEKRGLAFLCTRFAA
CEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHCCHHHHHHHHHH
KEAFSKAIGLGMRWPMTWRAMELLNQPSGEPAPHCTGELAEWVRERGLTVRVSVSDEHEY
HHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCEEEEEECCCCCH
AVAFAIAERGGQLAAPQSEPASN
HHHHEEHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA