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The map label for this gene is dsbD [H]

Identifier: 94311330

GI number: 94311330

Start: 2604191

End: 2606029

Strand: Direct

Name: dsbD [H]

Synonym: Rmet_2394

Alternate gene names: 94311330

Gene position: 2604191-2606029 (Clockwise)

Preceding gene: 94311329

Following gene: 94311331

Centisome position: 66.3

GC content: 65.04

Gene sequence:

>1839_bases
TTGGCTTTTTATCGGCGCATCGTAGCGATCTTTCTCCTGTGTGGTTGTGCGGTCGGCAGTGCGTGGGCGGACGGCCTTTT
TCCCTCCTGGGGCCGCAGCGAGCGGCAATTTCTGGACGTTGCCGAAGTTCTCAAGCTGGACGCTGTGCAGCAGCAGGGCG
ATTCGTTCTCGGCCGCTGGACACGTTGCCGATGGCTACTACGTTTATCGCCATGCCATCAAGTTGGTCGATGCGCAGGGC
CATGAAGTCAGCCTGACGCTTCCGGCAGGAACAGCCAAACACGACGAATTCTTTGGCGATACGGAAATCTATACGGGCGA
TGCCCTCAATCTGCGCTTTCCCGCCACCGCCCCCGGCCCGCTGACACTGCATTGGCAAGGGTGCGCGGAGGCAGGTATCT
GCTATCCGCCGCAGACCATGAATGTGGCATTGCCGGCAGTGGTGGCCGGCACATCCCCGACCGGCAATGACTCCGTACAG
CGGAGTTCGGCTTTGACCTCCACCAACACAGTCAGCTTGGGCGGAGCTACCGAGGTGGCAGAGGATCAAGCGGCAGCGCA
GCGCCTAGCAGCATTGGGCCCCGTGTGGGGAACACTGCTGTTTTTTGGCTTCGGCTTGCTGCTCGCTTTCACACCATGCT
CGCTCCCGATGATCCCCATCGTCTCCACCATGGTCGTCGGCAGCCAGGCCAAGCCGCGGCGGGCTTTCTTCCTCTCTCTG
TCCTATGTCCTGGCGATGGCGGGCACCTACGCCGCGGTGGGCGTGGCCGCTGGCTTGGCCGGGGCCAACCTGCAAGCCAC
ACTGCAATCGCCTTGGCTGCTCGGAGCGTTTGCAGCCTTGTTCCTGGTCCTGGCGAGTTCACTGTTCGGCCTGTTCGAGC
TGCAGATGCCCTCGGCGCTGATCAATCGGGTCGAATCCGCCGGTAGAGATCGCTCGGGCGGGAGCATCTCCGGCGCGGCG
GCGCTGGGCTTCCTCTCGGCGCTTCTGGTCGGGCCTTGCATGACCGCTCCATTGGCAGGCGCATTGCTGTACATCGGGCA
GACCGGCAGCGCGGTCTACGGTGGCATGGCCTTGTTCGCGCTGGGTTTGGGCATGGGACTGCCCCTGCTGGCCATCGCCG
TGTTCGGTGCCCGGGTCCTGCCACGGCCTGGCGCGTGGATGGACCGCGTGCGCGTGGCATTCGGCTACGTCATGGTGGGC
ATGGCCGTGATGATGCTGACGCGCTTCCTGCCCGGCACGGTCAGCCTGGTTCTGTGGGGCGCATGGGTCTTGTCGGTGGC
GATTGGCCTGATCGCGTGGGGCCAGGCCGTGGCAGCGAAGCATCGGCTGGCATGGTCGCTGCGGTCCGGCGCCGTCTTCG
CCGGCTTGTGGTCCATCCTGATGCTGGTCGGCGCGGCCTCTGGCGGCGAATCGGCATTGCAGCCGCTGGCCCACCTGCGC
GGTGGTTCGACTTCGCCAGCACCGGCGGCGGGCGGCGTCGCTTACCTGCAGGCGAAATCGGTCGAGGACGTGGATGCGCA
TTTGGCACAGGCCGCTTCGCGCGGCCAATGGACCCTGATCGACTTCTACGCCGACTGGTGCGTCAGTTGCCATGTGATCG
AACGCAACGTATTCGGCGACCCCGCCGTCGCGTCCCGCCTGGCCCGGATGCAGGTCGTGCGACCAGATGTGACGCGCAAT
GATGCGACCGATCAGGCCTTGCTCAAGCATTGGGGTGTCATGGGGCCGCCCACGCTCATTCTGGTTGGCCCGGACGGTAC
GGAACGCCGGGACCTGCGCGTCGTCGGTGAGATCGATGCCCGCGCCTTCCTGGTGCGCTTGGACAAGGCAGGTTCCTGA

Upstream 100 bases:

>100_bases
TGATGGCATCCCCGTCCCCCACGGGCCATTGGGGGGACCTTTAGTTTCGCTTAATCGGGTCATCGCATGATCCAGGCAGC
TTTGCTTGGAGGACTCGGAT

Downstream 100 bases:

>100_bases
TGATCAGCGTAGGTCCGTTCTCCGTCCAAGTCGTTGCCGTCTTCCTGGCCGTCCTGCTGGCCTGGGCGGTGGCGCGCATG
GTTGCCAAGCGGTTGCCCGA

Product: Thiol:disulfide interchange protein

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 612; Mature: 611

Protein sequence:

>612_residues
MAFYRRIVAIFLLCGCAVGSAWADGLFPSWGRSERQFLDVAEVLKLDAVQQQGDSFSAAGHVADGYYVYRHAIKLVDAQG
HEVSLTLPAGTAKHDEFFGDTEIYTGDALNLRFPATAPGPLTLHWQGCAEAGICYPPQTMNVALPAVVAGTSPTGNDSVQ
RSSALTSTNTVSLGGATEVAEDQAAAQRLAALGPVWGTLLFFGFGLLLAFTPCSLPMIPIVSTMVVGSQAKPRRAFFLSL
SYVLAMAGTYAAVGVAAGLAGANLQATLQSPWLLGAFAALFLVLASSLFGLFELQMPSALINRVESAGRDRSGGSISGAA
ALGFLSALLVGPCMTAPLAGALLYIGQTGSAVYGGMALFALGLGMGLPLLAIAVFGARVLPRPGAWMDRVRVAFGYVMVG
MAVMMLTRFLPGTVSLVLWGAWVLSVAIGLIAWGQAVAAKHRLAWSLRSGAVFAGLWSILMLVGAASGGESALQPLAHLR
GGSTSPAPAAGGVAYLQAKSVEDVDAHLAQAASRGQWTLIDFYADWCVSCHVIERNVFGDPAVASRLARMQVVRPDVTRN
DATDQALLKHWGVMGPPTLILVGPDGTERRDLRVVGEIDARAFLVRLDKAGS

Sequences:

>Translated_612_residues
MAFYRRIVAIFLLCGCAVGSAWADGLFPSWGRSERQFLDVAEVLKLDAVQQQGDSFSAAGHVADGYYVYRHAIKLVDAQG
HEVSLTLPAGTAKHDEFFGDTEIYTGDALNLRFPATAPGPLTLHWQGCAEAGICYPPQTMNVALPAVVAGTSPTGNDSVQ
RSSALTSTNTVSLGGATEVAEDQAAAQRLAALGPVWGTLLFFGFGLLLAFTPCSLPMIPIVSTMVVGSQAKPRRAFFLSL
SYVLAMAGTYAAVGVAAGLAGANLQATLQSPWLLGAFAALFLVLASSLFGLFELQMPSALINRVESAGRDRSGGSISGAA
ALGFLSALLVGPCMTAPLAGALLYIGQTGSAVYGGMALFALGLGMGLPLLAIAVFGARVLPRPGAWMDRVRVAFGYVMVG
MAVMMLTRFLPGTVSLVLWGAWVLSVAIGLIAWGQAVAAKHRLAWSLRSGAVFAGLWSILMLVGAASGGESALQPLAHLR
GGSTSPAPAAGGVAYLQAKSVEDVDAHLAQAASRGQWTLIDFYADWCVSCHVIERNVFGDPAVASRLARMQVVRPDVTRN
DATDQALLKHWGVMGPPTLILVGPDGTERRDLRVVGEIDARAFLVRLDKAGS
>Mature_611_residues
AFYRRIVAIFLLCGCAVGSAWADGLFPSWGRSERQFLDVAEVLKLDAVQQQGDSFSAAGHVADGYYVYRHAIKLVDAQGH
EVSLTLPAGTAKHDEFFGDTEIYTGDALNLRFPATAPGPLTLHWQGCAEAGICYPPQTMNVALPAVVAGTSPTGNDSVQR
SSALTSTNTVSLGGATEVAEDQAAAQRLAALGPVWGTLLFFGFGLLLAFTPCSLPMIPIVSTMVVGSQAKPRRAFFLSLS
YVLAMAGTYAAVGVAAGLAGANLQATLQSPWLLGAFAALFLVLASSLFGLFELQMPSALINRVESAGRDRSGGSISGAAA
LGFLSALLVGPCMTAPLAGALLYIGQTGSAVYGGMALFALGLGMGLPLLAIAVFGARVLPRPGAWMDRVRVAFGYVMVGM
AVMMLTRFLPGTVSLVLWGAWVLSVAIGLIAWGQAVAAKHRLAWSLRSGAVFAGLWSILMLVGAASGGESALQPLAHLRG
GSTSPAPAAGGVAYLQAKSVEDVDAHLAQAASRGQWTLIDFYADWCVSCHVIERNVFGDPAVASRLARMQVVRPDVTRND
ATDQALLKHWGVMGPPTLILVGPDGTERRDLRVVGEIDARAFLVRLDKAGS

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=608, Percent_Identity=35.8552631578947, Blast_Score=347, Evalue=2e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 63979; Mature: 63848

Theoretical pI: Translated: 7.52; Mature: 7.52

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFYRRIVAIFLLCGCAVGSAWADGLFPSWGRSERQFLDVAEVLKLDAVQQQGDSFSAAG
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
HVADGYYVYRHAIKLVDAQGHEVSLTLPAGTAKHDEFFGDTEIYTGDALNLRFPATAPGP
CCCCCHHHHHHHHHHEECCCCEEEEEECCCCCCCHHCCCCCEEEECCEEEEECCCCCCCC
LTLHWQGCAEAGICYPPQTMNVALPAVVAGTSPTGNDSVQRSSALTSTNTVSLGGATEVA
EEEEECCCCCCCCCCCCCCCCEEECEEEECCCCCCCCHHHHHHHCCCCCEEECCCCHHHH
EDQAAAQRLAALGPVWGTLLFFGFGLLLAFTPCSLPMIPIVSTMVVGSQAKPRRAFFLSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHH
SYVLAMAGTYAAVGVAAGLAGANLQATLQSPWLLGAFAALFLVLASSLFGLFELQMPSAL
HHHHHHHHHHHHHHHHHHCCCCCCEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
INRVESAGRDRSGGSISGAAALGFLSALLVGPCMTAPLAGALLYIGQTGSAVYGGMALFA
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHH
LGLGMGLPLLAIAVFGARVLPRPGAWMDRVRVAFGYVMVGMAVMMLTRFLPGTVSLVLWG
HHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
AWVLSVAIGLIAWGQAVAAKHRLAWSLRSGAVFAGLWSILMLVGAASGGESALQPLAHLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHC
GGSTSPAPAAGGVAYLQAKSVEDVDAHLAQAASRGQWTLIDFYADWCVSCHVIERNVFGD
CCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCEEEEHHHHHHHHEEEEEECCCCCC
PAVASRLARMQVVRPDVTRNDATDQALLKHWGVMGPPTLILVGPDGTERRDLRVVGEIDA
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCCEEEEECCCC
RAFLVRLDKAGS
EEEEEEECCCCC
>Mature Secondary Structure 
AFYRRIVAIFLLCGCAVGSAWADGLFPSWGRSERQFLDVAEVLKLDAVQQQGDSFSAAG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
HVADGYYVYRHAIKLVDAQGHEVSLTLPAGTAKHDEFFGDTEIYTGDALNLRFPATAPGP
CCCCCHHHHHHHHHHEECCCCEEEEEECCCCCCCHHCCCCCEEEECCEEEEECCCCCCCC
LTLHWQGCAEAGICYPPQTMNVALPAVVAGTSPTGNDSVQRSSALTSTNTVSLGGATEVA
EEEEECCCCCCCCCCCCCCCCEEECEEEECCCCCCCCHHHHHHHCCCCCEEECCCCHHHH
EDQAAAQRLAALGPVWGTLLFFGFGLLLAFTPCSLPMIPIVSTMVVGSQAKPRRAFFLSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHH
SYVLAMAGTYAAVGVAAGLAGANLQATLQSPWLLGAFAALFLVLASSLFGLFELQMPSAL
HHHHHHHHHHHHHHHHHHCCCCCCEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
INRVESAGRDRSGGSISGAAALGFLSALLVGPCMTAPLAGALLYIGQTGSAVYGGMALFA
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHH
LGLGMGLPLLAIAVFGARVLPRPGAWMDRVRVAFGYVMVGMAVMMLTRFLPGTVSLVLWG
HHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
AWVLSVAIGLIAWGQAVAAKHRLAWSLRSGAVFAGLWSILMLVGAASGGESALQPLAHLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHC
GGSTSPAPAAGGVAYLQAKSVEDVDAHLAQAASRGQWTLIDFYADWCVSCHVIERNVFGD
CCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCEEEEHHHHHHHHEEEEEECCCCCC
PAVASRLARMQVVRPDVTRNDATDQALLKHWGVMGPPTLILVGPDGTERRDLRVVGEIDA
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCCEEEEECCCC
RAFLVRLDKAGS
EEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA