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The map label for this gene is ccmB [H]

Identifier: 94311322

GI number: 94311322

Start: 2598223

End: 2598909

Strand: Direct

Name: ccmB [H]

Synonym: Rmet_2386

Alternate gene names: 94311322

Gene position: 2598223-2598909 (Clockwise)

Preceding gene: 94311321

Following gene: 94311323

Centisome position: 66.14

GC content: 63.17

Gene sequence:

>687_bases
ATGAGCCGGCCCCTCGTTGCCAATCCGGTATTTGTCGTGATGCGCCGGGACTTGAAGCTCGCCTTGCTCCGAAGGTCAGA
CGCGCTGATACCTCTTTGCTTCTTTGTCGTGGTCGTCAGTCTGTTTCCATTGGGTATCGGCCCCGAGCGCGAAATGCTCC
GACGGATCGCTCCGGGCGTCCTGTGGGTATCGGCGTTGCTGGCCAGCATGCTTTCGCTCAATCGCCTGTTCGAGCAGGAT
CACGCCGATGGCACGCTGGAGCAGATGATGCTGTCGCCAGCGCCGTTGGCCATGTTGGTCGTCGGCAAGATCGCGGCGCA
TTGGCTGTTGTCCGGTTTGCCCTTGGCCTTGCTTGCGCCCGCGCTGGCATTGCAGTTCGACCTGCCTGCCTTGTCCCTCT
GGATTTTGACCGCATCGCTCGTTATCGGTACGCCGGTGCTCAGCCTCATCGGCGCCGTCGGCGCGGGGCTGACGCTGGGC
GTACGCGCAGGGGGTGTCCTCGTTGCTGTGCTGGTGCTGCCGCTCTACATCCCGGTGCTGATCTTCGGTGCCGGCGCGGT
CGATGCGTCGATCATCGGTCAGGGAGCGTCGGCCAACCTCTCTTTGCTCGCCGCCGTGTTCGTCTTGGCGGCGTTCTTCA
CGCCATTCGCAGCGAGTGCATCGCTGCGCATCGCACTGGAGTACTGA

Upstream 100 bases:

>100_bases
GTGAACTGATCCATCGGCACCAGTCACGCGGCGGCATGGTCGTTCTGACGAGTCACCAGGAGCTGGCCTTGAAAACTTCT
CAGACCGTCCGGATGGGGGC

Downstream 100 bases:

>100_bases
GGAGCGAAGCGTATGGTCAACTGGTTCAAGTTTTCATCTCCCAAGGCGTTCTACCCACTCGCGGGGAAGCTCGTCCCTTG
GCTCGGCGTGACCGCCGCGG

Product: heme exporter membrane protein/cytochrome c maturation protein B

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CcmB [H]

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MSRPLVANPVFVVMRRDLKLALLRRSDALIPLCFFVVVVSLFPLGIGPEREMLRRIAPGVLWVSALLASMLSLNRLFEQD
HADGTLEQMMLSPAPLAMLVVGKIAAHWLLSGLPLALLAPALALQFDLPALSLWILTASLVIGTPVLSLIGAVGAGLTLG
VRAGGVLVAVLVLPLYIPVLIFGAGAVDASIIGQGASANLSLLAAVFVLAAFFTPFAASASLRIALEY

Sequences:

>Translated_228_residues
MSRPLVANPVFVVMRRDLKLALLRRSDALIPLCFFVVVVSLFPLGIGPEREMLRRIAPGVLWVSALLASMLSLNRLFEQD
HADGTLEQMMLSPAPLAMLVVGKIAAHWLLSGLPLALLAPALALQFDLPALSLWILTASLVIGTPVLSLIGAVGAGLTLG
VRAGGVLVAVLVLPLYIPVLIFGAGAVDASIIGQGASANLSLLAAVFVLAAFFTPFAASASLRIALEY
>Mature_227_residues
SRPLVANPVFVVMRRDLKLALLRRSDALIPLCFFVVVVSLFPLGIGPEREMLRRIAPGVLWVSALLASMLSLNRLFEQDH
ADGTLEQMMLSPAPLAMLVVGKIAAHWLLSGLPLALLAPALALQFDLPALSLWILTASLVIGTPVLSLIGAVGAGLTLGV
RAGGVLVAVLVLPLYIPVLIFGAGAVDASIIGQGASANLSLLAAVFVLAAFFTPFAASASLRIALEY

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG2386

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmB/CycW/HelB family [H]

Homologues:

Organism=Escherichia coli, GI1788528, Length=215, Percent_Identity=44.1860465116279, Blast_Score=148, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003544 [H]

Pfam domain/function: PF03379 CcmB [H]

EC number: NA

Molecular weight: Translated: 23894; Mature: 23763

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRPLVANPVFVVMRRDLKLALLRRSDALIPLCFFVVVVSLFPLGIGPEREMLRRIAPGV
CCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHH
LWVSALLASMLSLNRLFEQDHADGTLEQMMLSPAPLAMLVVGKIAAHWLLSGLPLALLAP
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHH
ALALQFDLPALSLWILTASLVIGTPVLSLIGAVGAGLTLGVRAGGVLVAVLVLPLYIPVL
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
IFGAGAVDASIIGQGASANLSLLAAVFVLAAFFTPFAASASLRIALEY
HHCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEC
>Mature Secondary Structure 
SRPLVANPVFVVMRRDLKLALLRRSDALIPLCFFVVVVSLFPLGIGPEREMLRRIAPGV
CCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHH
LWVSALLASMLSLNRLFEQDHADGTLEQMMLSPAPLAMLVVGKIAAHWLLSGLPLALLAP
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHH
ALALQFDLPALSLWILTASLVIGTPVLSLIGAVGAGLTLGVRAGGVLVAVLVLPLYIPVL
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
IFGAGAVDASIIGQGASANLSLLAAVFVLAAFFTPFAASASLRIALEY
HHCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]